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Extensive Bilateral LemierreSyndrome due to Methicillin-Resistant Staphylococcus epidermidis in a Patient with Lung Adenocarcinoma Lemierresyndrome (LS) is a septic thrombophlebitis of the internal jugular vein (IJV) following an oropharyngeal infection. LS is commonly caused by normal anaerobic flora and treated with appropriate antibiotics and anticoagulation therapy. Although the incidence of disease is very rare, 15% cases of LS are fatal even in the antibiotic era because of disseminated
Lemierresyndrome: More than "the forgotten disease". A 54-year-old woman presented with fever, spasmodic torticollis, ptosis, and chemosis in her left eye. CT venous angiography revealed cavernous sinus thrombosis (CST) and left internal jugular vein thrombosis (IJVT) (figure, A), cervical MRI detected a retropharyngeal abscess and epidural empyema (figure, B and C), and chest X-ray showed multiple pulmonary opacities (figure, D). The clinical/radiologic picture, due to anaerobic septicemia (...) , was consistent with Lemierresyndrome (LS), the so-called "forgotten disease."(1) Extensive neuroimaging studies are mandatory to detect an abscess in the neck of patients with CST and IJVT for early diagnosis and treatment. LS is still relevant today.
A Case of LemierreSyndrome Secondary to Otitis Media and Mastoiditis Lemierre'ssyndrome is a rare clinical condition that generally develops secondary to oropharyngeal infection caused by Fusobacterium necrophorum, which is an anaerobic bacteria. A 62-year-old patient with diabetes mellitus presented with internal jugular vein and sigmoid sinus-transverse sinus thrombophlebitis, accompanying otitis media and mastoiditis that developed after an upper airway infection. Interestingly, there were (...) air bubbles in both the internal jugular vein and transverse sinus. Vancomycin and meropenem were started and a right radical mastoidectomy was performed. The patient's clinical picture completely resolved in 14 days. High mortality and morbidity may be prevented with a prompt diagnosis of Lemierre'ssyndrome.
Lemierre'ssyndrome after evacuation of the uterus: a case report Even minor surgical interventions can have serious complications. Lemierre'ssyndrome is rare and to our best knowledge never before described after gynecological surgery; however, it should be considered in case of rapidly developing respiratory problems after even simple surgical procedures.
Extensive thoracolumbosacral vertebral osteomyelitis after Lemierresyndrome. To present a unique case of multilevel vertebral osteomyelitis after Lemierre syndrome.A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierresyndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging (...) revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine.Although the blood cultures obtained at the initial admission for Lemierresyndrome revealed Fusobacterium species and Streptococcus milleri, the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence
Septic thrombosis of the internal jugular vein: Lemierre'ssyndrome revisited. Study of the clinical evolution of a primary ear, nose, and throat infection complicated by septic thrombophlebitis of the internal jugular vein.Retrospective case-control study.From 1998 to 2010, 23 patients at our institution were diagnosed with a septic thrombosis of the internal jugular vein. Diagnostics included microbiologic analysis and imaging such as computed tomography, magnetic resonance imaging (...) , and ultrasound. Therapy included broad-spectrum antibiotics, surgery of the primary infectious lesion, and postoperative anticoagulation. The patients were retrospectively analyzed.The primary infection sites were found in the middle ear (11), oropharynx (8), sinus (3), and oral cavity (1). Fourteen patients needed intensive care unit treatment for a mean duration of 6 days. Seven patients were intubated, and two developed severe acute respiratory distress syndrome. An oropharynx primary infection site
Lemierre'ssyndrome - an unusual complication of otitis externa in a young, healthy female. Lemierre'ssyndrome, which affects previously healthy, young adults, is a rare complication secondary to infections in the head and neck that result in septic thrombophlebitis of the internal jugular vein.This paper reports a case of a young, healthy female with malignant otitis externa, which resulted in the development of Lemierre'ssyndrome. A review of the relevant literature was also carried out (...) . This involved a search of the Medline database using multiple search terms including 'Lemierre', 'septic thrombophlebitis', 'otitis externa', 'internal jugular vein thrombosis' and 'management'.The patient presented with fever, left-sided otalgia, otorrhoea, neck swelling and pain. She was subsequently diagnosed with Lemierre'ssyndrome and managed accordingly.Lemierre's syndrome is a potentially fatal complication associated with significant morbidity. A high index of suspicion is required for prompt
Thromboembolic and bleeding complications in patients with Lemierresyndrome: an individual patient-level meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence (...) is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome, the choice of effect measure, how subgroup variables are stratified etc. In order to assess the robustness of the findings of the meta-analysis, the analyses
Lemierre'ssyndrome presenting to the ED: rapidly fatal sepsis caused by methicillin-susceptible Staphylococcus aureus Staphylococcus protein A type t044. We describe the case of a fatal septic illness in a previously healthy young man caused by community-acquired methicillin-susceptible Staphylococcus aureus of Staphylococcus protein A (spa) type t044. The patient developed a devastating Lemierre-like syndrome with extensive thrombosis of inferior vena cava and iliac veins with multiple (...) metastatic septic emboli of the lungs. He presented to the emergency department with rapidly progressing sepsis followed by multiple organ dysfunction syndrome. Recognition of such virulent community-acquired strains is of great importance because they could prove to be emerging pathogens for life-threatening diseases.
A 10-month-old with Lemierresyndrome complicated by purulent pericarditis. Lemierresyndrome is a potentially life-threatening septic thrombophlebitis associated with a neck infection. We present a case of a 10-month-old female infant with Lemierresyndrome complicated by thrombotic strokes and purulent pericarditis. A healthy 10-month-old female infant presented to the pediatric emergency department of our tertiary care center complaining of 5 days of fever to 105°F and 1 day of neck (...) stiffness and decreased oral intake. In the pediatric emergency department, she developed septic shock, requiring vasopressor support, endotracheal intubation, and broad-spectrum antibiotics. A computed tomographic scan demonstrated a neck abscess associated with a right internal jugular thrombus and septic emboli to her lungs and brain. This constellation was consistent with Lemierresyndrome. Further studies demonstrated the thrombus extended into her left ventricular outflow tract. She was emergently
in the ill adolescent with a history of sore throat, fever and neck pain. Lemierre’ssyndrome is characterized by: A recent oropharyngeal infection Internal jugular venous thrombosis Isolation of anaerobic pathogens (classically Fusobacterium necrophorum ) Usual first clinical presentation of Lemierresyndrome via Karkos et al. Laryngoscope The classic cause is Fusobacterium necrophorum , a gram-negative anaerobe that is part of the normal oral, GI and female GU flora. There is a slight fame to male (...) . Check with your microbiology/Infectious Disease local experts first – but a sample initial regimen for the patient with suspected Lemierre’s could include IV penicillin and metronidazole or monotherapy with clindamycin for 2–6 weeks. Again, and I can’t drive this home enough, if you are suspicious about Lemierre’s please OBTAIN AN ANAEROBIC BLOOD CULTURE! Take Home Points Lemierre’ssyndrome is caused by septic thromboembolic from the jugular veins The classic cause is Fusobacterium necrophorum
(high resolution, high contrast) …including specific view of areas with bruising and tenderness!  List 4 conditions with similar presentation to as child abuse (shownotes) osteogenesis imperfecta osteopenia of prematurity scurvy copper deficiency Menkes disease disuse osteopenia (nonambulatory or minimally ambulatory children) chronic disease (kidney and liver)  List causes of pathologic fractures in children. bone tumors, rickets, McCune-Albright syndrome, juvenile osteoporosis, chronic renal (...) or pelvis fractures, overuse injuries Infection : septic arthritis, osteomyelitis, myositis, Lyme disease Inflammation : transient synovitis, juvenile rheumatoid arthritis, rheumatic fever Neoplasm : leukaemia, osteogenic/Ewing’s sarcoma, metastatic disease Haematologic disorders : haemophilia, sickle cell disease Miscellaneous : Legg-Calvé-Parthes disease, slipped capital femoral epiphysis  Provide a differential diagnosis of limp in the toddler, school-aged child and adolescent. Toddler School
LemierreSyndromeLemierreSyndrome Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 LemierreSyndromeLemierreSyndrome Aka: Lemierre (...) empiric treatment Avoid s s s VII. References Edson (2011) Internal Medicine, Mayo Conference, Kauai Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "LemierreSyndrome." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Throat Disease About FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency
English-language articles and used the following Medical Subject Headings terms: “acute bronchitis,” “respiratory tract infection,” “pharyngitis,” “rhinosinusitis,” and “the common cold”. The focus of the article was limited to healthy adults without chronic lung disease (such as cystic fibrosis, bronchiectasis, and chronic obstructive pulmonary disease) or immunocompromising conditions (congenital or acquired immunodeficiencies, HIV infection, chronic renal failure, nephrotic syndrome, leukemia (...) that Fusobacterium necrophorum is implicated in approximately 10% to 20% of endemic pharyngitis cases in adolescents ( , ). It has also been implicated as a cause of Lemierresyndrome ( ), which is a rare and life-threatening condition. The role of F necrophorum in pharyngitis and subsequent development of Lemierresyndrome warrant further study. Routine testing for F necrophorum is not recommended, but clinicians should remain vigilant and suspect Lemierresyndrome in adolescent and young adult patients
The Changing Face of an Old Disease: Case Report of Nonclassical Lemierre'sSyndrome Caused by a Panton-Valentine Leucocidin-Positive Methicillin-Susceptible Staphylococcus aureus Isolate 22760040 2013 01 03 2018 12 01 1098-660X 50 9 2012 Sep Journal of clinical microbiology J. Clin. Microbiol. The changing face of an old disease: case report of nonclassical Lemierre'ssyndrome caused by a Panton-Valentine leucocidin-positive methicillin-susceptible Staphylococcus aureus isolate. 3144-5 10.1128 (...) /JCM.00939-12 Molloy Aoife A Towersey Gareth G Shackleton David D Aali Adnan A Ash Steven S eng Letter Comment 2012 07 03 United States J Clin Microbiol 7505564 0095-1137 IM J Clin Microbiol. 2011 May;49(5):2063-6 21430106 Female Humans LemierreSyndrome complications diagnosis Methicillin-Resistant Staphylococcus aureus isolation & purification Staphylococcal Infections complications diagnosis 2012 7 5 6 0 2012 7 5 6 0 2013 1 4 6 0 ppublish 22760040 JCM.00939-12 10.1128/JCM.00939-12 PMC3421801
LemierreSyndrome Secondary to Community-acquired Methicillin-resistant Staphylococcus Aureus Infection Associated with Cavernous Sinus Thromboses. LemierreSyndrome (LS) is a highly aggressive rare disease process with a predilection for young, healthy adolescents. Often beginning with a primary cervicofacial infection, LS rapidly progresses to thrombophlebitis of the cerebral vasculature, metastatic infection, and septicemia. Untreated LS can be rapidly fatal. Thrombus within the cerebral (...) vasculature can have devastating neurological effects. Advances in antibacterial therapy have resulted in a global decline in the incidence of LS, and clinicians may not consider LS early in the disease process. Although the mortality of LS has declined, the morbidity associated with the disease has increased, particularly the neurological sequelae.This report will provide readers with a better understanding of the etiology, clinical presentation, evaluation methods, and appropriate treatment of LS.We
Acute parotitis due to MRSA causing Lemierreâ€™s syndrome We report a case of septic thrombophlebitis of the right internal jugular vein linked with right-sided acute parotitis caused by methicillin-resistant Staphylococcus aureus (MRSA) in a patient who had recently undergone a pylorus-preserving pancreaticoduodenectomy. Our case is unique because acute parotitis is a less-recognized cause of Lemierre'ssyndrome, never previously linked with MRSA infection in this context. We review (...) the literature on diagnosis and management of Lemierre'ssyndrome caused by acute parotitis. Prompt diagnosis and aggressive antibiotics ensured a favourable outcome.