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Lemierre Syndrome

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41. Extensive Bilateral Lemierre Syndrome due to Methicillin-Resistant Staphylococcus epidermidis in a Patient with Lung Adenocarcinoma Full Text available with Trip Pro

Extensive Bilateral Lemierre Syndrome due to Methicillin-Resistant Staphylococcus epidermidis in a Patient with Lung Adenocarcinoma Lemierre syndrome (LS) is a septic thrombophlebitis of the internal jugular vein (IJV) following an oropharyngeal infection. LS is commonly caused by normal anaerobic flora and treated with appropriate antibiotics and anticoagulation therapy. Although the incidence of disease is very rare, 15% cases of LS are fatal even in the antibiotic era because of disseminated

2015 Tuberculosis and respiratory diseases

42. Lemierre syndrome: More than "the forgotten disease". Full Text available with Trip Pro

Lemierre syndrome: More than "the forgotten disease". A 54-year-old woman presented with fever, spasmodic torticollis, ptosis, and chemosis in her left eye. CT venous angiography revealed cavernous sinus thrombosis (CST) and left internal jugular vein thrombosis (IJVT) (figure, A), cervical MRI detected a retropharyngeal abscess and epidural empyema (figure, B and C), and chest X-ray showed multiple pulmonary opacities (figure, D). The clinical/radiologic picture, due to anaerobic septicemia (...) , was consistent with Lemierre syndrome (LS), the so-called "forgotten disease."(1) Extensive neuroimaging studies are mandatory to detect an abscess in the neck of patients with CST and IJVT for early diagnosis and treatment. LS is still relevant today.

2013 Neurology

43. A Case of Lemierre Syndrome Secondary to Otitis Media and Mastoiditis Full Text available with Trip Pro

A Case of Lemierre Syndrome Secondary to Otitis Media and Mastoiditis Lemierre's syndrome is a rare clinical condition that generally develops secondary to oropharyngeal infection caused by Fusobacterium necrophorum, which is an anaerobic bacteria. A 62-year-old patient with diabetes mellitus presented with internal jugular vein and sigmoid sinus-transverse sinus thrombophlebitis, accompanying otitis media and mastoiditis that developed after an upper airway infection. Interestingly, there were (...) air bubbles in both the internal jugular vein and transverse sinus. Vancomycin and meropenem were started and a right radical mastoidectomy was performed. The patient's clinical picture completely resolved in 14 days. High mortality and morbidity may be prevented with a prompt diagnosis of Lemierre's syndrome.

2014 Case Reports in Emergency Medicine

44. Lemierre's syndrome after evacuation of the uterus: a case report Full Text available with Trip Pro

Lemierre's syndrome after evacuation of the uterus: a case report Even minor surgical interventions can have serious complications. Lemierre's syndrome is rare and to our best knowledge never before described after gynecological surgery; however, it should be considered in case of rapidly developing respiratory problems after even simple surgical procedures.

2014 Clinical Case Reports

45. Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre syndrome. Full Text available with Trip Pro

Extensive thoracolumbosacral vertebral osteomyelitis after Lemierre syndrome. To present a unique case of multilevel vertebral osteomyelitis after Lemierre syndrome.A previously healthy 27-year-old man presented in the Emergency Department in septic shock because of Lemierre syndrome for which he was subsequently treated with intravenous benzylpenicillin for 2 months. Two and a half months later, the patient was readmitted with severe back pain without neurological deficits or fever. Imaging (...) revealed an extensive vertebral osteomyelitis of the complete thoracic, lumbar and sacral spine.Although the blood cultures obtained at the initial admission for Lemierre syndrome revealed Fusobacterium species and Streptococcus milleri, the cultures from the spinal biopsies remained negative. Histology of the spinal biopsies showed a purulent sclerosing osteomyelitis. The patient was successfully treated with intravenous piperacillin and tazobactam. Despite persisting back pain, no recurrence

2014 European Spine Journal

46. Septic thrombosis of the internal jugular vein: Lemierre's syndrome revisited. Full Text available with Trip Pro

Septic thrombosis of the internal jugular vein: Lemierre's syndrome revisited. Study of the clinical evolution of a primary ear, nose, and throat infection complicated by septic thrombophlebitis of the internal jugular vein.Retrospective case-control study.From 1998 to 2010, 23 patients at our institution were diagnosed with a septic thrombosis of the internal jugular vein. Diagnostics included microbiologic analysis and imaging such as computed tomography, magnetic resonance imaging (...) , and ultrasound. Therapy included broad-spectrum antibiotics, surgery of the primary infectious lesion, and postoperative anticoagulation. The patients were retrospectively analyzed.The primary infection sites were found in the middle ear (11), oropharynx (8), sinus (3), and oral cavity (1). Fourteen patients needed intensive care unit treatment for a mean duration of 6 days. Seven patients were intubated, and two developed severe acute respiratory distress syndrome. An oropharynx primary infection site

2014 Laryngoscope

47. Lemierre's syndrome - an unusual complication of otitis externa in a young, healthy female. (Abstract)

Lemierre's syndrome - an unusual complication of otitis externa in a young, healthy female. Lemierre's syndrome, which affects previously healthy, young adults, is a rare complication secondary to infections in the head and neck that result in septic thrombophlebitis of the internal jugular vein.This paper reports a case of a young, healthy female with malignant otitis externa, which resulted in the development of Lemierre's syndrome. A review of the relevant literature was also carried out (...) . This involved a search of the Medline database using multiple search terms including 'Lemierre', 'septic thrombophlebitis', 'otitis externa', 'internal jugular vein thrombosis' and 'management'.The patient presented with fever, left-sided otalgia, otorrhoea, neck swelling and pain. She was subsequently diagnosed with Lemierre's syndrome and managed accordingly.Lemierre's syndrome is a potentially fatal complication associated with significant morbidity. A high index of suspicion is required for prompt

2014 Journal of Laryngology & Otology

48. Thromboembolic and bleeding complications in patients with Lemierre syndrome: an individual patient-level meta-analysis

Thromboembolic and bleeding complications in patients with Lemierre syndrome: an individual patient-level meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence (...) is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome, the choice of effect measure, how subgroup variables are stratified etc. In order to assess the robustness of the findings of the meta-analysis, the analyses

2016 PROSPERO

49. A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology Full Text available with Trip Pro

and collecting specimens for analysis for a disease process. It is very easy to access critical information about a specific body site just by consulting the table of contents. Within each chapter, there is a table describing the specimen needs regarding a variety of etiologic agents that one may suspect as causing the illness. The test methods in the tables are listed in priority order according to the recommendations of the authors and reviewers. When room temperature is specified for a certain time period (...) A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious

2018 Infectious Diseases Society of America

50. Lemierre's syndrome presenting to the ED: rapidly fatal sepsis caused by methicillin-susceptible Staphylococcus aureus Staphylococcus protein A type t044. (Abstract)

Lemierre's syndrome presenting to the ED: rapidly fatal sepsis caused by methicillin-susceptible Staphylococcus aureus Staphylococcus protein A type t044. We describe the case of a fatal septic illness in a previously healthy young man caused by community-acquired methicillin-susceptible Staphylococcus aureus of Staphylococcus protein A (spa) type t044. The patient developed a devastating Lemierre-like syndrome with extensive thrombosis of inferior vena cava and iliac veins with multiple (...) metastatic septic emboli of the lungs. He presented to the emergency department with rapidly progressing sepsis followed by multiple organ dysfunction syndrome. Recognition of such virulent community-acquired strains is of great importance because they could prove to be emerging pathogens for life-threatening diseases.

2013 American Journal of Emergency Medicine

51. A 10-month-old with Lemierre syndrome complicated by purulent pericarditis. (Abstract)

A 10-month-old with Lemierre syndrome complicated by purulent pericarditis. Lemierre syndrome is a potentially life-threatening septic thrombophlebitis associated with a neck infection. We present a case of a 10-month-old female infant with Lemierre syndrome complicated by thrombotic strokes and purulent pericarditis. A healthy 10-month-old female infant presented to the pediatric emergency department of our tertiary care center complaining of 5 days of fever to 105°F and 1 day of neck (...) stiffness and decreased oral intake. In the pediatric emergency department, she developed septic shock, requiring vasopressor support, endotracheal intubation, and broad-spectrum antibiotics. A computed tomographic scan demonstrated a neck abscess associated with a right internal jugular thrombus and septic emboli to her lungs and brain. This constellation was consistent with Lemierre syndrome. Further studies demonstrated the thrombus extended into her left ventricular outflow tract. She was emergently

2013 American Journal of Emergency Medicine

52. Lemierre’s syndrome

in the ill adolescent with a history of sore throat, fever and neck pain. Lemierre’s syndrome is characterized by: A recent oropharyngeal infection Internal jugular venous thrombosis Isolation of anaerobic pathogens (classically Fusobacterium necrophorum ) Usual first clinical presentation of Lemierre syndrome via Karkos et al. Laryngoscope The classic cause is Fusobacterium necrophorum , a gram-negative anaerobe that is part of the normal oral, GI and female GU flora. There is a slight fame to male (...) . Check with your microbiology/Infectious Disease local experts first – but a sample initial regimen for the patient with suspected Lemierre’s could include IV penicillin and metronidazole or monotherapy with clindamycin for 2–6 weeks. Again, and I can’t drive this home enough, if you are suspicious about Lemierre’s please OBTAIN AN ANAEROBIC BLOOD CULTURE! Take Home Points Lemierre’s syndrome is caused by septic thromboembolic from the jugular veins The classic cause is Fusobacterium necrophorum

2016 PEM Blog

53. CRACKCast E176 – Pediatric Musculoskeletal Disorders

(high resolution, high contrast) …including specific view of areas with bruising and tenderness! [4] List 4 conditions with similar presentation to as child abuse (shownotes) osteogenesis imperfecta osteopenia of prematurity scurvy copper deficiency Menkes disease disuse osteopenia (nonambulatory or minimally ambulatory children) chronic disease (kidney and liver) [5] List causes of pathologic fractures in children. bone tumors, rickets, McCune-Albright syndrome, juvenile osteoporosis, chronic renal (...) or pelvis fractures, overuse injuries Infection : septic arthritis, osteomyelitis, myositis, Lyme disease Inflammation : transient synovitis, juvenile rheumatoid arthritis, rheumatic fever Neoplasm : leukaemia, osteogenic/Ewing’s sarcoma, metastatic disease Haematologic disorders : haemophilia, sickle cell disease Miscellaneous : Legg-Calvé-Parthes disease, slipped capital femoral epiphysis [11] Provide a differential diagnosis of limp in the toddler, school-aged child and adolescent. Toddler School

2018 CandiEM

54. Lemierre Syndrome

Lemierre Syndrome Lemierre Syndrome Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Lemierre Syndrome Lemierre Syndrome Aka: Lemierre (...) empiric treatment Avoid s s s VII. References Edson (2011) Internal Medicine, Mayo Conference, Kauai Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Lemierre Syndrome." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Throat Disease About FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency

2015 FP Notebook

55. Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention Full Text available with Trip Pro

English-language articles and used the following Medical Subject Headings terms: “acute bronchitis,” “respiratory tract infection,” “pharyngitis,” “rhinosinusitis,” and “the common cold”. The focus of the article was limited to healthy adults without chronic lung disease (such as cystic fibrosis, bronchiectasis, and chronic obstructive pulmonary disease) or immunocompromising conditions (congenital or acquired immunodeficiencies, HIV infection, chronic renal failure, nephrotic syndrome, leukemia (...) that Fusobacterium necrophorum is implicated in approximately 10% to 20% of endemic pharyngitis cases in adolescents ( , ). It has also been implicated as a cause of Lemierre syndrome ( ), which is a rare and life-threatening condition. The role of F necrophorum in pharyngitis and subsequent development of Lemierre syndrome warrant further study. Routine testing for F necrophorum is not recommended, but clinicians should remain vigilant and suspect Lemierre syndrome in adolescent and young adult patients

2016 American College of Physicians

56. The Changing Face of an Old Disease: Case Report of Nonclassical Lemierre's Syndrome Caused by a Panton-Valentine Leucocidin-Positive Methicillin-Susceptible Staphylococcus aureus Isolate Full Text available with Trip Pro

The Changing Face of an Old Disease: Case Report of Nonclassical Lemierre's Syndrome Caused by a Panton-Valentine Leucocidin-Positive Methicillin-Susceptible Staphylococcus aureus Isolate 22760040 2013 01 03 2018 12 01 1098-660X 50 9 2012 Sep Journal of clinical microbiology J. Clin. Microbiol. The changing face of an old disease: case report of nonclassical Lemierre's syndrome caused by a Panton-Valentine leucocidin-positive methicillin-susceptible Staphylococcus aureus isolate. 3144-5 10.1128 (...) /JCM.00939-12 Molloy Aoife A Towersey Gareth G Shackleton David D Aali Adnan A Ash Steven S eng Letter Comment 2012 07 03 United States J Clin Microbiol 7505564 0095-1137 IM J Clin Microbiol. 2011 May;49(5):2063-6 21430106 Female Humans Lemierre Syndrome complications diagnosis Methicillin-Resistant Staphylococcus aureus isolation & purification Staphylococcal Infections complications diagnosis 2012 7 5 6 0 2012 7 5 6 0 2013 1 4 6 0 ppublish 22760040 JCM.00939-12 10.1128/JCM.00939-12 PMC3421801

2012 Journal of clinical microbiology

57. Lemierre's syndrome: Diagnosis in the emergency department. (Abstract)

Lemierre's syndrome: Diagnosis in the emergency department. A 15-year-old boy presented with signs of sepsis and a history of sore throat, fevers and shortness of breath. Full examination revealed an erythematous oropharynx and mild tonsillar swelling. He rapidly deteriorated requiring admission to intensive care. Blood cultures grew Fusobacterium necrophorum and an ultrasound scan performed for left neck tenderness confirmed internal jugular vein thrombosis. He was diagnosed with Lemierre's (...) syndrome. This condition results from pharyngitis or tonsillitis with bacterial spread to the lateral pharyngeal space. Internal jugular vein thrombosis ensues with septic emboli and metastatic infections that most frequently involve the lungs. Although increasing in incidence, diagnosis is often delayed. We discuss why and describe its clinical presentation, investigations of choice and treatment strategies.© 2012 The Authors. EMA © 2012 Australasian College for Emergency Medicine and Australasian

2012 Emergency medicine Australasia

58. Lemierre Syndrome Secondary to Community-acquired Methicillin-resistant Staphylococcus Aureus Infection Associated with Cavernous Sinus Thromboses. Full Text available with Trip Pro

Lemierre Syndrome Secondary to Community-acquired Methicillin-resistant Staphylococcus Aureus Infection Associated with Cavernous Sinus Thromboses. Lemierre Syndrome (LS) is a highly aggressive rare disease process with a predilection for young, healthy adolescents. Often beginning with a primary cervicofacial infection, LS rapidly progresses to thrombophlebitis of the cerebral vasculature, metastatic infection, and septicemia. Untreated LS can be rapidly fatal. Thrombus within the cerebral (...) vasculature can have devastating neurological effects. Advances in antibacterial therapy have resulted in a global decline in the incidence of LS, and clinicians may not consider LS early in the disease process. Although the mortality of LS has declined, the morbidity associated with the disease has increased, particularly the neurological sequelae.This report will provide readers with a better understanding of the etiology, clinical presentation, evaluation methods, and appropriate treatment of LS.We

2012 Journal of Emergency Medicine

59. Mycoplasma pneumoniae preceding Lemierre's syndrome due to Fusobacterium nucleatum complicated by acute Epstein-Barr virus (EBV) infectious mononucleosis in an immunocompetent host. (Abstract)

Mycoplasma pneumoniae preceding Lemierre's syndrome due to Fusobacterium nucleatum complicated by acute Epstein-Barr virus (EBV) infectious mononucleosis in an immunocompetent host. We report an unusual case of Lemierre's syndrome due to a rare species of Fusobacterium, that is, Fusobacterium nucleatum preceded by Mycoplasma pneumoniae pharyngitis and followed later by Epstein-Barr virus infectious mononucleosis.Copyright © 2013 Elsevier Inc. All rights reserved.

2012 Heart & Lung

60. Acute parotitis due to MRSA causing Lemierre’s syndrome Full Text available with Trip Pro

Acute parotitis due to MRSA causing Lemierre’s syndrome We report a case of septic thrombophlebitis of the right internal jugular vein linked with right-sided acute parotitis caused by methicillin-resistant Staphylococcus aureus (MRSA) in a patient who had recently undergone a pylorus-preserving pancreaticoduodenectomy. Our case is unique because acute parotitis is a less-recognized cause of Lemierre's syndrome, never previously linked with MRSA infection in this context. We review (...) the literature on diagnosis and management of Lemierre's syndrome caused by acute parotitis. Prompt diagnosis and aggressive antibiotics ensured a favourable outcome.

2018 Oxford Medical Case Reports

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