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Lemierre Syndrome

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41. Lemierre's syndrome - an unusual complication of otitis externa in a young, healthy female. (Abstract)

Lemierre's syndrome - an unusual complication of otitis externa in a young, healthy female. Lemierre's syndrome, which affects previously healthy, young adults, is a rare complication secondary to infections in the head and neck that result in septic thrombophlebitis of the internal jugular vein.This paper reports a case of a young, healthy female with malignant otitis externa, which resulted in the development of Lemierre's syndrome. A review of the relevant literature was also carried out (...) . This involved a search of the Medline database using multiple search terms including 'Lemierre', 'septic thrombophlebitis', 'otitis externa', 'internal jugular vein thrombosis' and 'management'.The patient presented with fever, left-sided otalgia, otorrhoea, neck swelling and pain. She was subsequently diagnosed with Lemierre's syndrome and managed accordingly.Lemierre's syndrome is a potentially fatal complication associated with significant morbidity. A high index of suspicion is required for prompt

2014 Journal of Laryngology & Otology

42. A Case of Lemierre Syndrome Secondary to Otitis Media and Mastoiditis Full Text available with Trip Pro

A Case of Lemierre Syndrome Secondary to Otitis Media and Mastoiditis Lemierre's syndrome is a rare clinical condition that generally develops secondary to oropharyngeal infection caused by Fusobacterium necrophorum, which is an anaerobic bacteria. A 62-year-old patient with diabetes mellitus presented with internal jugular vein and sigmoid sinus-transverse sinus thrombophlebitis, accompanying otitis media and mastoiditis that developed after an upper airway infection. Interestingly, there were (...) air bubbles in both the internal jugular vein and transverse sinus. Vancomycin and meropenem were started and a right radical mastoidectomy was performed. The patient's clinical picture completely resolved in 14 days. High mortality and morbidity may be prevented with a prompt diagnosis of Lemierre's syndrome.

2014 Case Reports in Emergency Medicine

43. Lemierre syndrome: More than "the forgotten disease". Full Text available with Trip Pro

Lemierre syndrome: More than "the forgotten disease". A 54-year-old woman presented with fever, spasmodic torticollis, ptosis, and chemosis in her left eye. CT venous angiography revealed cavernous sinus thrombosis (CST) and left internal jugular vein thrombosis (IJVT) (figure, A), cervical MRI detected a retropharyngeal abscess and epidural empyema (figure, B and C), and chest X-ray showed multiple pulmonary opacities (figure, D). The clinical/radiologic picture, due to anaerobic septicemia (...) , was consistent with Lemierre syndrome (LS), the so-called "forgotten disease."(1) Extensive neuroimaging studies are mandatory to detect an abscess in the neck of patients with CST and IJVT for early diagnosis and treatment. LS is still relevant today.

2013 Neurology

44. A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology Full Text available with Trip Pro

and collecting specimens for analysis for a disease process. It is very easy to access critical information about a specific body site just by consulting the table of contents. Within each chapter, there is a table describing the specimen needs regarding a variety of etiologic agents that one may suspect as causing the illness. The test methods in the tables are listed in priority order according to the recommendations of the authors and reviewers. When room temperature is specified for a certain time period (...) A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious

2018 Infectious Diseases Society of America

45. The Changing Face of an Old Disease: Case Report of Nonclassical Lemierre's Syndrome Caused by a Panton-Valentine Leucocidin-Positive Methicillin-Susceptible Staphylococcus aureus Isolate Full Text available with Trip Pro

The Changing Face of an Old Disease: Case Report of Nonclassical Lemierre's Syndrome Caused by a Panton-Valentine Leucocidin-Positive Methicillin-Susceptible Staphylococcus aureus Isolate 22760040 2013 01 03 2018 12 01 1098-660X 50 9 2012 Sep Journal of clinical microbiology J. Clin. Microbiol. The changing face of an old disease: case report of nonclassical Lemierre's syndrome caused by a Panton-Valentine leucocidin-positive methicillin-susceptible Staphylococcus aureus isolate. 3144-5 10.1128 (...) /JCM.00939-12 Molloy Aoife A Towersey Gareth G Shackleton David D Aali Adnan A Ash Steven S eng Letter Comment 2012 07 03 United States J Clin Microbiol 7505564 0095-1137 IM J Clin Microbiol. 2011 May;49(5):2063-6 21430106 Female Humans Lemierre Syndrome complications diagnosis Methicillin-Resistant Staphylococcus aureus isolation & purification Staphylococcal Infections complications diagnosis 2012 7 5 6 0 2012 7 5 6 0 2013 1 4 6 0 ppublish 22760040 JCM.00939-12 10.1128/JCM.00939-12 PMC3421801

2012 Journal of clinical microbiology

46. Thromboembolic and bleeding complications in patients with Lemierre syndrome: an individual patient-level meta-analysis

Thromboembolic and bleeding complications in patients with Lemierre syndrome: an individual patient-level meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence (...) is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome, the choice of effect measure, how subgroup variables are stratified etc. In order to assess the robustness of the findings of the meta-analysis, the analyses

2016 PROSPERO

47. Lemierre's syndrome presenting to the ED: rapidly fatal sepsis caused by methicillin-susceptible Staphylococcus aureus Staphylococcus protein A type t044. (Abstract)

Lemierre's syndrome presenting to the ED: rapidly fatal sepsis caused by methicillin-susceptible Staphylococcus aureus Staphylococcus protein A type t044. We describe the case of a fatal septic illness in a previously healthy young man caused by community-acquired methicillin-susceptible Staphylococcus aureus of Staphylococcus protein A (spa) type t044. The patient developed a devastating Lemierre-like syndrome with extensive thrombosis of inferior vena cava and iliac veins with multiple (...) metastatic septic emboli of the lungs. He presented to the emergency department with rapidly progressing sepsis followed by multiple organ dysfunction syndrome. Recognition of such virulent community-acquired strains is of great importance because they could prove to be emerging pathogens for life-threatening diseases.

2013 American Journal of Emergency Medicine

48. A 10-month-old with Lemierre syndrome complicated by purulent pericarditis. (Abstract)

A 10-month-old with Lemierre syndrome complicated by purulent pericarditis. Lemierre syndrome is a potentially life-threatening septic thrombophlebitis associated with a neck infection. We present a case of a 10-month-old female infant with Lemierre syndrome complicated by thrombotic strokes and purulent pericarditis. A healthy 10-month-old female infant presented to the pediatric emergency department of our tertiary care center complaining of 5 days of fever to 105°F and 1 day of neck (...) stiffness and decreased oral intake. In the pediatric emergency department, she developed septic shock, requiring vasopressor support, endotracheal intubation, and broad-spectrum antibiotics. A computed tomographic scan demonstrated a neck abscess associated with a right internal jugular thrombus and septic emboli to her lungs and brain. This constellation was consistent with Lemierre syndrome. Further studies demonstrated the thrombus extended into her left ventricular outflow tract. She was emergently

2013 American Journal of Emergency Medicine

49. Lemierre’s syndrome

in the ill adolescent with a history of sore throat, fever and neck pain. Lemierre’s syndrome is characterized by: A recent oropharyngeal infection Internal jugular venous thrombosis Isolation of anaerobic pathogens (classically Fusobacterium necrophorum ) Usual first clinical presentation of Lemierre syndrome via Karkos et al. Laryngoscope The classic cause is Fusobacterium necrophorum , a gram-negative anaerobe that is part of the normal oral, GI and female GU flora. There is a slight fame to male (...) . Check with your microbiology/Infectious Disease local experts first – but a sample initial regimen for the patient with suspected Lemierre’s could include IV penicillin and metronidazole or monotherapy with clindamycin for 2–6 weeks. Again, and I can’t drive this home enough, if you are suspicious about Lemierre’s please OBTAIN AN ANAEROBIC BLOOD CULTURE! Take Home Points Lemierre’s syndrome is caused by septic thromboembolic from the jugular veins The classic cause is Fusobacterium necrophorum

2016 PEM Blog

50. Lemierre Syndrome

Lemierre Syndrome Lemierre Syndrome Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Lemierre Syndrome Lemierre Syndrome Aka: Lemierre (...) empiric treatment Avoid s s s VII. References Edson (2011) Internal Medicine, Mayo Conference, Kauai Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Lemierre Syndrome." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Throat Disease About FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency

2015 FP Notebook

51. Lemierre's syndrome: Diagnosis in the emergency department. (Abstract)

Lemierre's syndrome: Diagnosis in the emergency department. A 15-year-old boy presented with signs of sepsis and a history of sore throat, fevers and shortness of breath. Full examination revealed an erythematous oropharynx and mild tonsillar swelling. He rapidly deteriorated requiring admission to intensive care. Blood cultures grew Fusobacterium necrophorum and an ultrasound scan performed for left neck tenderness confirmed internal jugular vein thrombosis. He was diagnosed with Lemierre's (...) syndrome. This condition results from pharyngitis or tonsillitis with bacterial spread to the lateral pharyngeal space. Internal jugular vein thrombosis ensues with septic emboli and metastatic infections that most frequently involve the lungs. Although increasing in incidence, diagnosis is often delayed. We discuss why and describe its clinical presentation, investigations of choice and treatment strategies.© 2012 The Authors. EMA © 2012 Australasian College for Emergency Medicine and Australasian

2012 Emergency medicine Australasia

52. Lemierre Syndrome Secondary to Community-acquired Methicillin-resistant Staphylococcus Aureus Infection Associated with Cavernous Sinus Thromboses. Full Text available with Trip Pro

Lemierre Syndrome Secondary to Community-acquired Methicillin-resistant Staphylococcus Aureus Infection Associated with Cavernous Sinus Thromboses. Lemierre Syndrome (LS) is a highly aggressive rare disease process with a predilection for young, healthy adolescents. Often beginning with a primary cervicofacial infection, LS rapidly progresses to thrombophlebitis of the cerebral vasculature, metastatic infection, and septicemia. Untreated LS can be rapidly fatal. Thrombus within the cerebral (...) vasculature can have devastating neurological effects. Advances in antibacterial therapy have resulted in a global decline in the incidence of LS, and clinicians may not consider LS early in the disease process. Although the mortality of LS has declined, the morbidity associated with the disease has increased, particularly the neurological sequelae.This report will provide readers with a better understanding of the etiology, clinical presentation, evaluation methods, and appropriate treatment of LS.We

2012 Journal of Emergency Medicine

53. Mycoplasma pneumoniae preceding Lemierre's syndrome due to Fusobacterium nucleatum complicated by acute Epstein-Barr virus (EBV) infectious mononucleosis in an immunocompetent host. (Abstract)

Mycoplasma pneumoniae preceding Lemierre's syndrome due to Fusobacterium nucleatum complicated by acute Epstein-Barr virus (EBV) infectious mononucleosis in an immunocompetent host. We report an unusual case of Lemierre's syndrome due to a rare species of Fusobacterium, that is, Fusobacterium nucleatum preceded by Mycoplasma pneumoniae pharyngitis and followed later by Epstein-Barr virus infectious mononucleosis.Copyright © 2013 Elsevier Inc. All rights reserved.

2012 Heart & Lung

54. CRACKCast E176 – Pediatric Musculoskeletal Disorders

(high resolution, high contrast) …including specific view of areas with bruising and tenderness! [4] List 4 conditions with similar presentation to as child abuse (shownotes) osteogenesis imperfecta osteopenia of prematurity scurvy copper deficiency Menkes disease disuse osteopenia (nonambulatory or minimally ambulatory children) chronic disease (kidney and liver) [5] List causes of pathologic fractures in children. bone tumors, rickets, McCune-Albright syndrome, juvenile osteoporosis, chronic renal (...) or pelvis fractures, overuse injuries Infection : septic arthritis, osteomyelitis, myositis, Lyme disease Inflammation : transient synovitis, juvenile rheumatoid arthritis, rheumatic fever Neoplasm : leukaemia, osteogenic/Ewing’s sarcoma, metastatic disease Haematologic disorders : haemophilia, sickle cell disease Miscellaneous : Legg-Calvé-Parthes disease, slipped capital femoral epiphysis [11] Provide a differential diagnosis of limp in the toddler, school-aged child and adolescent. Toddler School

2018 CandiEM

55. Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention Full Text available with Trip Pro

English-language articles and used the following Medical Subject Headings terms: “acute bronchitis,” “respiratory tract infection,” “pharyngitis,” “rhinosinusitis,” and “the common cold”. The focus of the article was limited to healthy adults without chronic lung disease (such as cystic fibrosis, bronchiectasis, and chronic obstructive pulmonary disease) or immunocompromising conditions (congenital or acquired immunodeficiencies, HIV infection, chronic renal failure, nephrotic syndrome, leukemia (...) that Fusobacterium necrophorum is implicated in approximately 10% to 20% of endemic pharyngitis cases in adolescents ( , ). It has also been implicated as a cause of Lemierre syndrome ( ), which is a rare and life-threatening condition. The role of F necrophorum in pharyngitis and subsequent development of Lemierre syndrome warrant further study. Routine testing for F necrophorum is not recommended, but clinicians should remain vigilant and suspect Lemierre syndrome in adolescent and young adult patients

2016 American College of Physicians

56. Acute parotitis due to MRSA causing Lemierre’s syndrome Full Text available with Trip Pro

Acute parotitis due to MRSA causing Lemierre’s syndrome We report a case of septic thrombophlebitis of the right internal jugular vein linked with right-sided acute parotitis caused by methicillin-resistant Staphylococcus aureus (MRSA) in a patient who had recently undergone a pylorus-preserving pancreaticoduodenectomy. Our case is unique because acute parotitis is a less-recognized cause of Lemierre's syndrome, never previously linked with MRSA infection in this context. We review (...) the literature on diagnosis and management of Lemierre's syndrome caused by acute parotitis. Prompt diagnosis and aggressive antibiotics ensured a favourable outcome.

2018 Oxford Medical Case Reports

57. Lemierre’s syndrome following perianal abscess: A case report Full Text available with Trip Pro

Lemierre’s syndrome following perianal abscess: A case report Lemierre's syndrome (LS) is a rare and life-threatening condition characterized by suppurative thrombophlebitis of the internal jugular vein (IJV), and a history of head and neck (H&N) sepsis. LS is usually caused by Fusobacterium necrophorum, which is part of the normal flora in the oro-pharynx, and the digestive and urogenital tracts. We here report the first case of LS following perianal sepsis.A 60-year-old man with a painful (...) surgery, urology, or obstetrics and gynaecology might also rarely encounter the disease. We present a case of LS complicating a perianal abscess that was successfully treated with good outcome.Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

2018 International journal of surgery case reports

58. Lemierre’s Syndrome Full Text available with Trip Pro

Lemierre’s Syndrome Lemierre's syndrome is a rare, life-threatening condition, which may be fatal if not properly treated. This disease refers to thrombophlebitis of the internal jugular vein, which is the result of bacterial sore throat infection (usually in the form of pharyngitis) that extends into the parapharyngeal space. However, it can result from other infective foci in the ear, nose, parotid glands, and paranasal sinuses. The bacteria typically responsible is Fusobacterium (...) necrophorum. Here, we describe a case of Lemierre's syndrome that occurred in a 20-year-old female who presented with neurological deficits following a two-week history of upper respiratory tract infection. Our case displayed typical findings of this rare condition with a review of the previous literature and also to emphasize the importance of high index of suspicion to reduce the mortality of this disease.

2018 Oman medical journal

59. Chromobacterium violaceum infection in chronic granulomatous disease: a case report and review of the literature Full Text available with Trip Pro

Chromobacterium violaceum infection in chronic granulomatous disease: a case report and review of the literature Introduction.Chromobacterium violaceum is an opportunistic human pathogen, associated with significant mortality, and has been reported in patients with chronic granulomatous disease (CGD), a genetic condition causing impaired phagocytosis. Case presentation. A 28-year-old man with a history of CGD presented with fever, pharyngitis, cervical lymphadenopathy and internal jugular vein (...) thrombosis, following travel to the rural Solomon Islands. C. violaceum was recovered from his blood. The patient recovered after treatment with meropenem and trimethoprim/sulfamethoxazole. Conclusion. To the best of our knowledge, this is the first case report of internal jugular vein thrombophlebitis (Lemierre's syndrome) caused by C. violaceum in a patient with CGD. A review of the literature demonstrated that the diagnosis of C. violaceum preceded the diagnosis of CGD in the majority of cases

2017 JMM Case Reports

60. Pulmonary embolism and internal jugular vein thrombosis as evocative clues of Lemierre’s syndrome: A case report and review of the literature Full Text available with Trip Pro

Pulmonary embolism and internal jugular vein thrombosis as evocative clues of Lemierre’s syndrome: A case report and review of the literature Lemierre's syndrome (LS) is an uncommon condition with oropharyngeal infections, internal jugular vein thrombosis, and systemic metastatic septic embolization as the main features. Fusobacterium species, a group of strictly anaerobic Gram negative rod shaped bacteria, are advocated to be the main pathogen involved. We report a case of LS complicated (...) by pulmonary embolism and pulmonary septic emboli that mimicked a neoplastic lung condition. A Medline search revealed 173 case reports of LS associated with internal jugular vein thrombosis that documented the type of microorganism. Data confirmed high prevalence in young males with Gram negative infections (83.2%). Pulmonary embolism was reported in 8.7% of cases mainly described in subjects with Gram positive infections (OR = 9.786; 95%CI: 2.577-37.168, P = 0.001), independently of age and gender. Only

2017 World journal of clinical cases

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