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Lemierre Syndrome

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21. Severe Sepsis Associated with Lemierre's Syndrome: A Rare but Life-Threatening Disease Full Text available with Trip Pro

Severe Sepsis Associated with Lemierre's Syndrome: A Rare but Life-Threatening Disease Background. The incidence of Lemierre's syndrome has increased in the past decade. This posttonsillitis complication may be life threatening. Case Presentation. A 19-year-old patient was admitted to Surgical Intensive Care Unit of a French University Hospital for high fever, low blood pressure, and haemoptysis following a sore throat episode. Blood analysis revealed a thrombopenia, an acute renal failure (...) , and an elevated lactate serum. Fusobacterium necrophorum was found in blood cultures. Computed tomography of the neck and lungs confirmed the diagnosis of Lemierre's syndrome: pleural effusions, bilateral lung infiltrates, and an internal jugular vein thrombosis. Fluid administration and antibiotic treatment were quickly initiated. Patient left the unit four days after his admission without any organ dysfunction. Conclusion. Lemierre's syndrome may lead to multiorgan dysfunction and should be rapidly

2016 Case reports in critical care

22. Thoughts on a 23-year-old athlete dying from the Lemierre Syndrome

the antibiotics. The Danish data suggest that in the 15-25 age group 1/70,000 will develop the Lemierre Syndrome. Even when patients survive the infection is likely equivalent to endocarditis (or perhaps even worse). We must develop a better strategy for adolescent sore throats. Reading about another death or even another patient who spends a month in the hospital including a week in the ICU for a disease that we might be able to prevent is tragic. She died and everyone around here is suffering her loss. We (...) Thoughts on a 23-year-old athlete dying from the Lemierre Syndrome db's Medical Rants » Blog Archive » Thoughts on a 23-year-old athlete dying from the Lemierre Syndrome Internal medicine, American health care, and especially medical education 2 Posted by rcentor | Posted on 03-11-2018 Category : Every time I read such a story my heart breaks, a small piece each time. More physicians have become aware of the Lemierre syndrome. We must also educate patients and families that sore throats

2018 db's Medical Rants blog

23. Lemierre's Syndrome Associated with Mechanical Ventilation and Profound Deafness Full Text available with Trip Pro

Lemierre's Syndrome Associated with Mechanical Ventilation and Profound Deafness Lemierre's syndrome is a rare disorder that is characterized by anaerobic organisms inducing a thrombophlebitis of the internal jugular vein (IJV) following a course of oropharyngeal infection. It often occurs in young and healthy patients. Clinicians continuously misinterpret early symptoms until infection disseminates systematically and life-threatening sepsis transpires. We report the case of a 58-year-old (...) female developing Lemierre's syndrome accompanied by invasive ventilation support and a profound deafness requiring the implementation of a cochlear implant. This is one of two reported cases of Lemierre's syndrome associated with mechanical ventilation support and the only case associated with a cochlear implant.

2017 Case reports in infectious diseases

24. Lemierre Syndrome After Tonsillectomy Full Text available with Trip Pro

Lemierre Syndrome After Tonsillectomy 29070428 2018 11 20 2018 11 20 1866-0452 114 40 2017 Oct 06 Deutsches Arzteblatt international Dtsch Arztebl Int Lemierre Syndrome After Tonsillectomy. 679 10.3238/arztebl.2017.0679 arztebl.2017.0679 Quast Daniel R DR Lotz Tanja A TA Breuer Thomas G K TGK eng Case Reports Journal Article Germany Dtsch Arztebl Int 101475967 1866-0452 0 Anti-Bacterial Agents IM Adolescent Anti-Bacterial Agents therapeutic use Female Fusobacterium necrophorum isolation (...) & purification Humans Lemierre Syndrome diagnosis drug therapy etiology Respiratory Distress Syndrome, Adult Tonsillectomy adverse effects 2017 10 27 6 0 2017 10 27 6 0 2018 11 21 6 0 ppublish 29070428 arztebl.2017.0679 10.3238/arztebl.2017.0679 PMC5963584

2017 Deutsches Ärzteblatt international

25. Human Infection with Fusobacterium necrophorum without Jugular Venous Thrombosis: A Varied Presentation of Lemierre's Syndrome Full Text available with Trip Pro

Human Infection with Fusobacterium necrophorum without Jugular Venous Thrombosis: A Varied Presentation of Lemierre's Syndrome Lemierre's syndrome is also known as postangina septicemia, which is commonly caused by Fusobacterium necrophorum also known as Necrobacillus and also by other microorganisms like Staphylococcus, Streptococcus, Peptostreptococcus, and Bacteroides. Though the disease starts as an upper respiratory tract infection, it may spread and cause thrombophlebitis of the internal (...) jugular vein. It may present itself through cranial nerve palsy or sepsis involving distant organs like the lungs or bones. It is also known as forgotten disease because of its rarity. Fusobacterium necrophorum usually causes infection in animals and rarely affects humans. We hereby present a case of Necrobacillus infection which did not cause any thrombophlebitis but resulted in severe pneumonia and acute kidney injury, leading to respiratory failure and requiring mechanical ventilation.

2017 Case reports in infectious diseases

26. Lemierre syndrome: a diagnostic dilemma in paediatric patients Full Text available with Trip Pro

Lemierre syndrome: a diagnostic dilemma in paediatric patients Lemierre's syndrome is a rare disease of the head and neck, characterized by an initial infection, usually within the oropharynx, which can develop into a septic thrombophlebitis. It can involve the jugular vein, facial veins and respiratory tract. A 7-year-old child attended our institution with a 1-week history of fever and cough. Initial imaging demonstrated a large left sided empyema with multiple cavitating lung lesions (...) and persisting pneumothoraces secondary to the development of a bronchopleural fistula. There was no clinical improvement, despite an initial course of antibiotics. A contrast enhanced computed tomography (CT) of the head and neck revealed left mastoiditis, multiple cerebral abscesses and thrombus within the left internal jugular vein. Antibiotic therapy was modified. The empyema was surgically drained and bronchopleural fistula repaired. This case illustrates an atypical presentation of Lemierre's syndrome

2017 Journal of surgical case reports

27. Lemierre's syndrome: forgotten, but not absent Full Text available with Trip Pro

Lemierre's syndrome: forgotten, but not absent Lemierre's syndrome is rare, with no known reported cases in the Caribbean thus far. We highlight a case of a young woman who presented with diabetic ketoacidosis precipitated by oral pharyngeal sepsis, whose condition rapidly deteriorated within 24 hours requiring ventilation and administration of antibiotics. Her sepsis was accompanied by internal jugular vein thrombosis in keeping with a diagnosis of Lemierre's syndrome, which was treated (...) aggressively with antibiotics, intensive care and mechanical ventilatory support in the intensive care unit. She made a full recovery. Though this is the first reported case in the Caribbean of this 'forgotten disease', it must not be forgotten because prognosis and outcome are markedly improved with prompt and aggressive treatment.© BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

2017 BMJ case reports

28. Brugada syndrome in a 4-year-old child with Lemierre syndrome—A case report Full Text available with Trip Pro

Brugada syndrome in a 4-year-old child with Lemierre syndrome—A case report Brugada syndrome is a rare arrhythmogenic disease with characteristic electrocardiogram (ECG) findings. Fever represents an important triggering factor. We report the case of a 4-year-old Saudi boy who was diagnosed with Lemierre syndrome and subsequently developed Brugada syndrome.

2017 Journal of the Saudi Heart Association

29. Lemierre's Syndrome with Cavernous Sinus Thrombosis Full Text available with Trip Pro

Lemierre's Syndrome with Cavernous Sinus Thrombosis 28381765 2018 11 13 1349-7235 56 7 2017 Internal medicine (Tokyo, Japan) Intern. Med. Lemierre's Syndrome with Cavernous Sinus Thrombosis. 887-888 10.2169/internalmedicine.56.7878 Kobayashi Koichi K Department of Clinical Research, National Hospital Organization Tokyo National Hospital, Japan. Matsui Hirotoshi H eng Journal Article 2017 04 01 Japan Intern Med 9204241 0918-2918 2017 4 7 6 0 2017 4 7 6 0 2017 4 7 6 1 ppublish 28381765 10.2169

2017 Internal Medicine

30. Septic thrombophlebitis of the internal jugular vein, a case of Lemierre's syndrome Full Text available with Trip Pro

Septic thrombophlebitis of the internal jugular vein, a case of Lemierre's syndrome An 18-year-old gentleman with a history of recurrent tonsillitis presented to the emergency room complaining of worsening sore throat. He was found to have a peritonisillar abscess, and imaging revealed a non-occlusive left internal jugular vein thrombosis. Lemierre's syndrome is a rare, potentially fatal condition characterized by internal jugular vein thrombosis with septicemia following an acute oropharyngeal (...) infection. While anticoagulation is the mainstay of treatment of deep venous thromboembolism (DVT) and pulmonary embolism (PE), the use of therapy is controversial in septic thrombophlebitis. This is counterintuitive since a common reported complication is pulmonary emboli. Early in the course of thrombophlebitis, while the thrombus is firmly attached, antibiotics may be all that is necessary to treat the condition.

2017 Intractable & rare diseases research

31. Lemierre's Syndrome Variant with External Jugular Vein Thrombosis Full Text available with Trip Pro

Lemierre's Syndrome Variant with External Jugular Vein Thrombosis 28502952 2018 11 13 1349-7235 56 10 2017 Internal medicine (Tokyo, Japan) Intern. Med. Lemierre's Syndrome Variant with External Jugular Vein Thrombosis. 1271-1272 10.2169/internalmedicine.56.8179 Takiguchi Junji J Department of Respiratory Medicine, Kobe Rosai Hospital, Japan. Sakamoto Hirokazu H Department of Respiratory Medicine, Kobe Rosai Hospital, Japan. Inoue Nobutaka N Department of Cardiovascular Medicine, Kobe Rosai (...) Hospital, Japan. eng Journal Article 2017 05 15 Japan Intern Med 9204241 0918-2918 Lemierre syndrome external jugular vein group C streptococcus 2017 5 16 6 0 2017 5 16 6 0 2017 5 16 6 1 ppublish 28502952 10.2169/internalmedicine.56.8179 PMC5491832 Lancet Infect Dis. 2012 Oct;12(10):808-15 22633566

2017 Internal Medicine

32. Lemierre's Syndrome Presenting as Multifocal Pyomyositis in a Young Child. (Abstract)

Lemierre's Syndrome Presenting as Multifocal Pyomyositis in a Young Child. Lemierre's syndrome is more common in young adults and the majority of patients present with pharyngitis. Multifocal pyomyositis is very rare in this setting and in young children. We present here a case of multifocal pyomyositis caused by Fusobacterium spp. in a young child. Fusobacterium should be considered in the differential diagnosis of multifocal pyomyositis of unclear etiology.

2017 Pediatric Infectious Dsease Journal

33. The long shadow of lemierre's syndrome. (Abstract)

The long shadow of lemierre's syndrome. Lemierre's syndrome is a rare and feared complication of pharyngitis, occurring most commonly in adolescents and young adults. It is typically defined by the constellation of septic internal jugular vein thrombophlebitis, pulmonary and other septic emboli, and sterilesite infection by Fusobacterium necrophorum. The rarity and severity of Lemierre's syndrome has made it an attractive subject for case reports but there is a paucity of evidence to inform (...) areas of persistent uncertainty. In recent years, heightened attention and controversy has focused upon speculation that a purported rise in the incidence of Lemierre's syndrome is due to reduced antibiotic prescribing for respiratory tract infections, that F. necrophorum is an under-appreciated cause of acute tonsillopharyngitis and that testing and targeted treatment would prevent cases of Lemierre's syndrome.© 2017 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

2017 Journal of Infection

34. Lemierre Syndrome Associated with Ipsilateral Recurrent Laryngeal Nerve Palsy: A Case Report and Review Full Text available with Trip Pro

Lemierre Syndrome Associated with Ipsilateral Recurrent Laryngeal Nerve Palsy: A Case Report and Review Lemierre syndrome (LS) is a rare life-threatening disease that is often caused by an acute oropharyngeal infection with a secondary thrombophlebitis of the internal jugular vein. LS rarely manifests as cranial nerve palsy. To the best of our knowledge, this is the second case report of LS associated with recurrent laryngeal nerve palsy. A 66-year-old female presented to a dental clinic

2016 NMC Case Report Journal

35. Fusobacterium necrophorum Pharyngitis Complicated by Lemierre's Syndrome Full Text available with Trip Pro

Fusobacterium necrophorum Pharyngitis Complicated by Lemierre's Syndrome We report the case of an 18-year-old woman who was referred to our outpatient clinic because of a 2-week history of sore throat, high fever, and neck tenderness unresponsive to a 7-day amoxicillin/clavulanic acid course. Infectious mononucleosis was initially suspected, but an extremely high value of procalcitonin and clinical deterioration suggested a bacterial sepsis, prompting the patient admission to our internal (...) medicine ward. Blood cultures were positive for Fusobacterium necrophorum. CT scan detected a parapharyngeal abscess, a right internal jugular vein thrombosis, and multiple bilateral lung abscesses, suggesting the diagnosis of Lemierre's syndrome. The patient was treated with a 2-week course of metronidazole and meropenem with a gradual clinical recovery. She was thereafter discharged home with metronidazole and amoxicillin/clavulanic acid for 14 days and a 3-month course of enoxaparin, experiencing

2016 Case reports in medicine

36. Methicillin-Resistant Staphylococcus aureus as a Cause of Lemierre's Syndrome. (Abstract)

Methicillin-Resistant Staphylococcus aureus as a Cause of Lemierre's Syndrome. Lemierre's syndrome (LS) or jugular vein suppurative thrombophlebitis is well described in literature. The organisms most often responsible are Fusobacterium necrophorum or anaerobic flora. We present a case of LS with an atypical microbiologic cause, methicillin-resistant Staphylococcus aureus. We also present retrospective review of all LS cases from our institution and identified 2 additional children with LS

2016 Pediatric Infectious Dsease Journal

37. Efficacy of non-vitamin K antagonist oral anticoagulants for Lemierre syndrome. (Abstract)

Efficacy of non-vitamin K antagonist oral anticoagulants for Lemierre syndrome. 27079502 2017 02 20 2017 08 17 1532-8171 34 10 2016 Oct The American journal of emergency medicine Am J Emerg Med Efficacy of non-vitamin K antagonist oral anticoagulants for Lemierre syndrome. 2059.e3-2059.e5 S0735-6757(16)00244-8 10.1016/j.ajem.2016.03.040 Kubota Masayuki M Hitachi General Hospital, Emergency and Critical Care Medicine Department, 2-1-1, Zyonan-cho, Hitachi-shi, Ibaraki, Japan, 3170077. Electronic (...) -49-6 Heparin NDU3J18APO edoxaban S4TF6I2330 Sulbactam IM Administration, Oral Ampicillin therapeutic use Anti-Bacterial Agents therapeutic use Anticoagulants therapeutic use Bacteremia complications drug therapy Factor Xa Inhibitors therapeutic use Female Heparin therapeutic use Humans Lemierre Syndrome complications drug therapy Middle Aged Pyridines therapeutic use Streptococcal Infections complications drug therapy Streptococcus pyogenes Sulbactam therapeutic use Thiazoles therapeutic use 2016

2016 American Journal of Emergency Medicine

38. Lemierre Syndrome of the Femoral Vein, Related to Fusobacterium necrophorum Abscess of Vastus Lateralis. (Abstract)

Lemierre Syndrome of the Femoral Vein, Related to Fusobacterium necrophorum Abscess of Vastus Lateralis. Lemierre syndrome is an uncommon, potentially lethal disorder combining acute oropharyngeal infection caused by Fusobacterium necrophorum, with jugular vein suppurative thrombosis, complicated by anaerobic sepsis with secondary multiple metastatic abscesses. Optimal treatment outcome with reduced or absence of sequelae can be achieved with early diagnosis.We present a clinical case (...) of Fusobacterium necrophorum abscess complicated with femoral vein thrombosis, called atypical localization of Lemierre syndrome. This uncommon disease was diagnosed on the basis of clinical, biological, and imaging tests, with a favorable outcome, after a well-orientated antibiotic and surgical course of therapy. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Since its first description in 1936, Lemierre syndrome has been reported in locations other than its initial oropharyngeal site. Because optimal

2016 Journal of Emergency Medicine

39. Pediatric Disseminated Lemierre Syndrome in 2 Infants: Not Too Young for an Ancient Disease. (Abstract)

Pediatric Disseminated Lemierre Syndrome in 2 Infants: Not Too Young for an Ancient Disease. The Lemierre syndrome is characterized by an oropharyngeal infection, thrombosis of the internal jugular vein, and multiple septic metastases. Fusobacterium necrophorum is a common cause of it. The incidence is 0.6 to 2.3 cases per million with a mortality rate of 4% to 18%. Its fast evolution and the possibility of severe complications require a high index of suspicion for its diagnosis. We present 2 (...) infants with Lemierre syndrome. The younger case, a 6-month-old infant, was fully recovered. In the other side, and despite an aggressive therapy, an 18-month-old infant developed cerebral palsy. We also provide a short literature review with a focus on clinical presentation and differential diagnosis in order to initiate an early and adequate therapy.

2015 Pediatric Emergency Care

40. Bacterial sinusitis and its frightening complications: subdural empyema and Lemierre syndrome Full Text available with Trip Pro

Bacterial sinusitis and its frightening complications: subdural empyema and Lemierre syndrome The symptoms of a previously healthy 14-year-old female with an initial history of tooth pain and swelling of the left maxillary evolved to a progressive headache and altered neurological findings characterized by auditory hallucinations, sleep disturbances, and aggressiveness. She was brought to the emergency department after 21 days of the initial symptoms. An initial computed tomography (CT) scan

2015 Autopsy & Case Reports

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