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212 results for

Lemierre Syndrome

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181. Lemierre syndrome in a 5-month-old male infant: Case report and review of the pediatric literature. (PubMed)

Lemierre syndrome in a 5-month-old male infant: Case report and review of the pediatric literature. To report, to the best of our knowledge, the youngest patient with Lemierre syndrome.Descriptive case report with review of the pediatric literature.Pediatric intensive care unit in a tertiary referral hospital.Systemic review of the literature, including PubMed (English-only journals) and major textbooks.We report a 5-month-old boy who presented with fever and a perforated left-sided otitis (...) media. He developed left-sided complicated otitis media with retroauricular fluid collection, mastoiditis, and temporomandibular joint effusion. The clinical picture was complicated by a left internal jugular vein and left lateral sinus thrombosis. Fusobacterium necrophorum grew in the pus culture.Low molecular weight heparin.No immunodeficiency and no thrombophilia were identified as predisposing conditions for Lemierre syndrome. Surgical drainage, early and adequate antibiotic treatment

2008 Pediatric Critical Care Medicine

182. Infection by Panton Valentine leukocidin-producing Staphylococcus aureus clinically mimicking Lemierre's syndrome. (Full text)

Infection by Panton Valentine leukocidin-producing Staphylococcus aureus clinically mimicking Lemierre's syndrome. Lemierre's syndrome is an oropharyngeal infection which leads to severe septic thrombophlebitis of the internal jugular vein and metastatic abscesses of the lungs and other organs. It is usually caused by Fusobacterium necrophorum, a Gram-negative obligate anaerobe. An unusual case of Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus infection masquerading (...) as Lemierre's syndrome is reported here. A 32-year-old fit and otherwise healthy male presented on Christmas morning with a boil on his left cheek for 2 days and generalized rash for 3 h. His general condition began to worsen, he developed facial swelling and loss of vision in the left eye and was transferred to the intensive care unit. His treatment was taken over by team of specialists and further investigations revealed thrombophlebitis of the left internal jugular vein and cavernous sinus thrombosis

2008 Journal of Medical Microbiology PubMed

183. Closed traumatic head injury: dural sinus and internal jugular vein thrombosis. (PubMed)

causes (eg, Lemierre's syndrome). A case of thrombosis of the transverse sinus, sigmoid sinus and internal jugular vein associated with a closed head injury as the result of a motorcycle accident is presented.

2008 Emergency Medicine Journal

184. Lemierre's syndrome: what are the roles for anticoagulation and long-term antibiotic therapy? (PubMed)

Lemierre's syndrome: what are the roles for anticoagulation and long-term antibiotic therapy? We wanted to describe what Lemierre's syndrome is and what risk factors may be involved, and to understand the roles, if any, of antibiotics and anticoagulants in the treatment of this syndrome.We performed a review of the pertinent literature regarding Lemierre's syndrome, as well as a review of otology, obstetrics and gynecology, and internal medicine literature looking at both anticoagulation (...) and long-term antibiotic treatment for septic thrombosis.The vast majority of patients with Lemierre's syndrome are successfully treated nonsurgically with antibiotics and, often, anticoagulation as well. Surgical intervention is reserved for those cases with persistent showering of septic emboli or continued propagation of the thrombosis. Although anticoagulation is commonly used in other specialties for similar septic thromboses, its role in Lemierre's syndrome is unclear at the present.Because

2008 Rhinology and Laryngology

185. Lemierre's syndrome with fourth nerve palsy. (PubMed)

Lemierre's syndrome with fourth nerve palsy. Lemierre's syndrome is characterized by acute oropharyngeal infection with secondary internal jugular vein thrombophlebitis and subsequent metastatic infections. The anaerobe Fusobacterium necrophorum is the usual etiologic agent, although other microorganisms, including Streptococcus, Staphylococcus, Enterococcus, Bacteroides, and Lactobacilli, may be present alone or in combination with F. necrophorum. Common sites of metastatic infection include (...) the lungs and joints. Thromboembolic complications, such as septic pulmonary embolism, persistent jugular vein occlusion, hepatic abscesses, and nephropathy, may occur. We report a case of Lemierre's syndrome in a 3-year-old Caucasian boy who subsequently presented with manifestations of a fourth (trochlear) nerve palsy.

2008 JAAPOS - Journal of the American Association for Pediatric Ophthalmology and Strabismus

186. Sore Throat

normal behaviour or functioning. Advantages and disadvantages have been discussed, including the possibility of spontaneous resolution. Children have sleep apnoea with daytime drowsiness and failure to thrive. Complications [ ] Suppurative complications . . . Cervical adenitis. . (rare). Lemierre's syndrome (rare - acute septicaemia and jugular vein thrombosis secondary to infection with Fusobacterium spp.). Nonsuppurative complications (rare in developed countries but still quite prevalent

2008 Mentor

187. Tonsillitis (Acute and Chronic)

dehydration. Peritonsillar abscess or cellulitis, parapharyngeal abscess, retropharyngeal abscess, or Lemierre's syndrome (as there is a risk of airway compromise or rupture of the abscess). Signs of marked systemic illness or sepsis. A suspected rare cause such as Kawasaki disease, diphtheria, or yersinial pharyngitis. Use clinical judgement to determine whether hospital admission is necessary in vulnerable people (eg, infants, very old people, and those who are immunosuppressed or immunocompromised

2008 Mentor

188. Rigors

a fit or convulsion. There is a wide range of conditions that can be associated with rigors, such as: Cardiac . . Lemierre's syndrome. . Pulmonary . . Genitourinary . . . . Obstetric Over half of women in labour experience shaking rigors. Epidurals and fever seem to be associated with the rigors. Rheumatological . . Infectious diseases . . . . (miliary). . Louse-borne relapsing fever (endemic in Ethiopia). GI . . . Medication reactions (usually intravenous) . Gentamicin. Vancomycin. Interleukin II

2008 Mentor

189. Septic pulmonary embolism: presenting features and clinical course of 14 patients. (PubMed)

) and included five women. Presenting symptoms included fever (93%), dyspnea (36%), pleuritic chest pain (29%), cough (14%), and hemoptysis (7%). The median duration of symptoms before diagnosis was 18 days (range, 5 to 180 days). A potential source or underlying condition that predisposed to SPE was identified in all 14 patients and included Lemierre syndrome (4 patients), central venous catheter infection (3 patients), prosthetic cardiac valve (2 patients), and pacemaker infection (2 patients). Two

2005 Chest

190. Prevotella bivia necrobacillosis following infectious mononucleosis. (PubMed)

Prevotella bivia necrobacillosis following infectious mononucleosis. A case of Lemierre's syndrome is reported. Although Fusobacterium species are commonly associated with this presentation, Prevotella bivia was the causative micro-organism identified in this case. The finding that disseminated anaerobic sepsis followed primary EBV infection led to the construction of a hypothetical model of infection.

2006 Journal of Infection

191. "My back is killing me". (Full text)

"My back is killing me". This is a case of a rare cause of back pain that presented to several clinicians before the diagnosis became obvious and the correct management was initiated. Lemierre's syndrome was confirmed at post mortem examination. We conclude that thoracic back pain should not be assumed to have a simple mechanical cause and that efforts should be made to discover the underlying aetiology.

2005 Emergency Medicine Journal PubMed

192. The changing pattern of Fusobacterium infections in humans: recent experience with Fusobacterium bacteraemia. (Full text)

patient presented with a classic Lemierre's syndrome. These results suggest an opportunistic pattern of modern fusobacterium infections.

2006 Clinical Microbiology and Infection PubMed

193. Lemierre's--the sinister sore throat. (PubMed)

Lemierre's--the sinister sore throat. Lemierre's syndrome is a rare and sometimes life threatening condition that requires prompt management. A case is reported of a previously healthy young male with Lemierre's syndrome. He developed internal jugular vein and cavernous sinus thrombosis, metastatic abscesses in the temporal lobe and lungs, temporal lobe venous infarction and severe thrombocytopaenia. Discussed are aspects of clinical presentation, diagnosis and management issues.

2007 Journal of Laryngology & Otology

194. Lemierre syndrome: two cases and a review. (PubMed)

Lemierre syndrome: two cases and a review. Lemierre syndrome is usually caused by an acute oropharyngeal infection in previously healthy young adults, resulting in thrombophlebitis of the internal jugular vein, leading to metastatic septic embolization and bacteraemia. The usual organism is Fusobacterium necrophorum. Lemierre syndrome, not so long ago labeled as the "forgotten disease," is on the rise. Today with increasing antibiotic-resistant organisms, and decreasing awareness (...) of the syndrome, subsequent re-emergence of this "forgotten disease" is becoming more common in clinical settings. Lemierre syndrome has significant morbidity. Cranial nerve complications associated with the condition have been increasingly diagnosed in the last few years. Looking back at literature on Lemierre syndrome, there have been review articles in medical and microbiology journals but rarely in otolaryngology journals. By presenting our cases we demonstrate the diverse presentations and severity

2007 Laryngoscope

195. Respiratory failure and hypercoagulability in a toddler with Lemierre's syndrome. (Full text)

Respiratory failure and hypercoagulability in a toddler with Lemierre's syndrome. A 3.5-year-old healthy boy with 4 days of fever was referred to the emergency department for respiratory distress. The physical examination was remarkable for stupor, tachycardia, tachypnea, and dyspnea. Initial blood tests showed pancytopenia. He rapidly developed torticollis. Computerized tomography of the neck revealed a thrombus in the internal jugular vein. A presumptive diagnosis of Lemierre's syndrome (...) was made and he was started on antibiotics and anticoagulation. He subsequently developed adult respiratory distress syndrome and required high frequency oscillatory ventilation for 9 days. Blood cultures were positive for Fusobacterium necrophorum. Screening for hypercoagulability revealed 2 known risk factors: a mutation in the prothrombin gene and elevated lipoprotein a.

2005 Pediatrics PubMed

196. Increased diagnosis of Lemierre syndrome and other Fusobacterium necrophorum infections at a Children's Hospital. (PubMed)

Increased diagnosis of Lemierre syndrome and other Fusobacterium necrophorum infections at a Children's Hospital. To assess the apparent increase in the diagnosis of Lemierre syndrome (LS) and other Fusobacterium necrophorum infections at a large children's hospital. Infections with F necrophorum ranged from peritonsillar abscess to potentially fatal LS. LS is an oropharyngeal infection characterized by septic thrombophlebitis of head and neck veins, complicated by dissemination of septic

2003 Pediatrics

197. Lemierre's syndrome: an unusual manifestation of spinal infection. (Full text)

Lemierre's syndrome: an unusual manifestation of spinal infection. We report a case of Lemierre's syndrome complicated by an epidural abscess. This manifestation of Lemierre's syndrome has not been described previously.

2006 The Journal of Bone and Joint Surgery British Volume PubMed

198. Fusobacterium necrophorum as the cause of recurrent sore throat: comparison of isolates from persistent sore throat syndrome and Lemierre's disease. (PubMed)

Fusobacterium necrophorum as the cause of recurrent sore throat: comparison of isolates from persistent sore throat syndrome and Lemierre's disease. Fusobacterium necrophorum is a well established cause of Lemierre's disease (LD); a syndrome characterised by severe sore throat, septicaemia, multiple abscesses and jugular vein thrombosis. There is no published data concerning the role of F. necrophorum in recurrent sore throats. As the result of an index case of persistent sore throat (...) attributable to this organism being diagnosed in our laboratory, a subsequent case controlled study (not yet published) isolated F. necrophorum from 21% (P=0.0001) of cases of persistent, recurrent and chronic sore throats. The object of this study was to compare isolates of F. necrophorum from cases of systemic disease with isolates from cases of persistent sore throat syndrome (PSTS) to ascertain whether strains of similar type were responsible for both throat and systemic disease or whether different

2005 Journal of Infection

199. A case of the otogenic variant of Lemierre's syndrome with atypical sequelae and a review of pediatric literature. (PubMed)

A case of the otogenic variant of Lemierre's syndrome with atypical sequelae and a review of pediatric literature. We report a case of an 8-year-old girl who presented with the clinical picture of Lemierre's syndrome (LS) secondary to bilateral mastoiditis. She developed unilateral sensorineural hearing loss (SNHL) along with internal jugular vein (IJV) thrombosis, septic arthritis of her ankle and cervical fasciitis. Combined antimicrobial, anticoagulant and surgical treatment helped reverse (...) all the effects of the sequelae, including nearly all the hearing loss. This is a unique case of this uncommon variant of the syndrome and with an uncommonly reported complication. The literature indicates that pediatric cases are a minority and enforces that successful management rests on awareness of the condition, vigil and promptness of communication of a multidisciplinary pediatric team.

2005 International Journal of Pediatric Otorhinolaryngology

200. Lemierre's syndrome presenting with peritonsillar abscess and VIth cranial nerve palsy. (PubMed)

Lemierre's syndrome presenting with peritonsillar abscess and VIth cranial nerve palsy. Lemierre's syndrome is characterized by acute oropharyngeal infection complicated by internal jugular venous thrombosis secondary to septic thrombophlebitis, and metastatic abscesses. We report a case of Lemierre's syndrome in an 18-year-old Caucasian woman presenting with a peritonsillar abscess and ipsilateral VIth cranial nerve palsy.

2006 Journal of Laryngology & Otology

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