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Late Pregnancy Bleeding

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2. Late Pregnancy Bleeding

Late Pregnancy Bleeding Late Pregnancy Bleeding Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Late Pregnancy Bleeding Late Pregnancy (...) Bleeding Aka: Late Pregnancy Bleeding , Second Trimester Bleeding , Third Trimester Bleeding , Vaginal Bleeding Late in Pregnancy From Related Chapters II. Epidemiology Late Pregnancy Bleeding complicates 4% of pregnancies III. Causes Major causes of bleeding (20%) Painless bleeding after 18-20 weeks gestation (30%) Painful bleeding Other causes or other genital tract infection Bloody show (may indicated ) Cervical polyp Cervical Vaginal IV. History Bleeding characteristics Amount of blood (pads per

2018 FP Notebook

3. Anticonvulsants and the risk of perinatal bleeding complications: A pregnancy cohort study

Anticonvulsants and the risk of perinatal bleeding complications: A pregnancy cohort study To examine the risk of postpartum hemorrhage (PPH) and neonatal bleeding complications associated with late-pregnancy exposure to anticonvulsant drugs (ACDs) that induce cytochrome P450 enzymes (ACDi) and alter the metabolism of vitamin K compared to other ACDs.We used a population-based cohort study stemming from a nationwide sample of publicly insured pregnant women with a liveborn infant from the 2000 (...) to 2010 Medicaid Analytic eXtract. ACDi (carbamazepine, phenobarbital, phenytoin, oxcarbazepine, topiramate) were compared to other ACDs dispensed during the last month of pregnancy. Relative risks (RRs) and 95% confidence intervals (CIs) of PPH and neonatal bleeding complications were estimated using generalized linear models with fine stratification on the propensity score to control for indication and other potential confounders.Among 11,572 women with an ACD prescription overlapping delivery, 2.6

2018 EvidenceUpdates

4. Tranexamic Acid in Pregnancies With Vaginal Bleeding

Model: Single Group Assignment Intervention Model Description: Tranexamic acid was prescribed for women with abnormal vaginal bleeding in the first trimester less than 20 weeks gestation (threatened and recurrent miscarriage) and Antepartum hemorrhage (abruption , placenta previa, and unknown causes for vaginal bleeding) Masking: None (Open Label) Primary Purpose: Treatment Official Title: Tranexamic Acid in Pregnancies With Early and Late Onset Vaginal Bleeding:One Arm Clinical Trial Actual Study (...) Tranexamic Acid in Pregnancies With Vaginal Bleeding Tranexamic Acid in Pregnancies With Vaginal Bleeding - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Tranexamic Acid in Pregnancies With Vaginal Bleeding

2018 Clinical Trials

5. Intra-abdominal Rupture of a Live Cervical Pregnancy with Placenta Accreta but Without Vaginal Bleeding (PubMed)

Intra-abdominal Rupture of a Live Cervical Pregnancy with Placenta Accreta but Without Vaginal Bleeding We describe an unusual ruptured ectopic pregnancy. The unique features of the case include abdominal pain without vaginal bleeding; cervical implantation and a placenta accreta; and the late presentation at 16 weeks of gestation without prior symptoms. Both the initial point-of-care ultrasound and the formal ultrasound were interpreted as showing an intrauterine pregnancy. The clinical (...) presentation was misleading; the correct diagnosis was made by magnetic resonance imaging. We show the ultrasonic images. We discuss cervical ectopic pregnancies, their diagnosis and management. The woman survived but required emergency hysterectomy and many units of blood.

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2018 Clinical Practice and Cases in Emergency Medicine

6. Fetal Growth Patterns in Pregnancies With First-Trimester Bleeding. (PubMed)

to 39 weeks of gestation. Mean birth weight at term was 88 g smaller, confirming differences in calculated fetal weight, and SGA neonates were delivered to 148 (8.5%), 9 (5.7%), and 33 (15.7%) women in the no bleeding, 1 day, and more than 1 day of bleeding groups, respectively.More than 1 day of first-trimester vaginal bleeding was associated with smaller estimated fetal weight late in pregnancy driven by smaller abdominal circumference. The magnitude of decrease in birth weight was small, albeit (...) Fetal Growth Patterns in Pregnancies With First-Trimester Bleeding. To assess the relationship between first-trimester vaginal bleeding and fetal growth patterns.We conducted a secondary analysis of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Fetal Growth Studies-Singletons, a prospective cohort study of low-risk, nonobese women with healthy lifestyles. Duration of bleeding was self-reported at enrollment (10 0/7 to 13 6/7 weeks of gestation

2018 Obstetrics and Gynecology

7. Cohort study: Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern

Cohort study: Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Article Text Aetiology Cohort study

2014 Evidence-Based Medicine (Requires free registration)

8. Expulsions and adverse events following immediate and later insertion of a levonorgestrel-releasing intrauterine system after medical termination of late first and second trimester pregnancy: A randomised controlled trial. (PubMed)

Expulsions and adverse events following immediate and later insertion of a levonorgestrel-releasing intrauterine system after medical termination of late first and second trimester pregnancy: A randomised controlled trial. To compare expulsions and adverse events (AEs) between immediate and delayed insertion of a levonorgestrel-releasing intrauterine system (LNG-IUS) following medical termination of pregnancy (MTOP).Randomised controlled trial.Helsinki University Hospital, Finland, January 2013 (...) -December 2014.Cohorts of 102 (gestational age 64-84 days, late first trimester) and 57 (gestational age 85-140 days, second trimester) women requesting MTOP and LNG-IUS contraception.LNG-IUS insertion occurred immediately (same day) or 2-4 weeks following MTOP. Follow-up visits were at 2-4 weeks, 3 months, and 1 year.LNG-IUS expulsion by 3 months and 1 year. AEs and bleeding profiles within 3 months.Following late first-trimester MTOP the LNG-IUS expulsion rates by 3 months were 14 (27.5

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2017 BJOG

9. Gynaecological and Obstetric Management of Women With Inherited Bleeding Disorders

menorrhagia is consistently reported to be 10% to 20% and is even higher in adolescents presenting with menorrhagia. Options Diagnostic tools and specific medical and, where appropriate, surgical alternatives to management are reviewed and evidence-based recommendations presented. Evidence A MEDLINE search of the English literature between January 1975 and November 2003 was performed using the following key words: menorrhagia, uterine bleeding, pregnancy, von Willebrand, congenital bleeding disorder (...) for her first and subsequent menstrual periods (III-C). 7. In adolescents presenting with menorrhagia, an inherited bleeding disorder should be excluded (III-B). When possible, investigation should be undertaken before oral contraceptive therapy is instituted, as the hormonally induced increase in factor VIII and vWF may mask the diagnosis (II-B). 8. Pregnancy in women with inherited bleeding disorders may require a multidisciplinary approach. A copy of their recommendations should be given

2018 Society of Obstetricians and Gynaecologists of Canada

10. Recommendations for the clinical interpretation of genetic variants and presentation of results to patients with inherited bleeding disorders

Recommendations for the clinical interpretation of genetic variants and presentation of results to patients with inherited bleeding disorders 116 | wileyonlinelibrary.com/journal/hae Haemophilia. 2019;25:116–126. © 2019 John Wiley & Sons Ltd 1 | INTRODUC TION Genetic diagnosis for patients with haemophilia has been a routine part of clinical practice in the United Kingdom for two decades. For patients with other inherited bleeding disorders, testing has previ- ously been variably implemented (...) because of reduced availability. This has changed in the last few years with the incorporation of next-generation sequencing (NGS) technology into clinical care for patients with bleeding disorders. Currently, genetic diagnosis can be offered to all patients in the United Kingdom with a bleeding disor- der for which the genetic basis is known. Even in those disorders that are suspected to be inherited but for which the genes responsible have not yet been identified, testing has been offered through

2019 United Kingdom Haemophilia Centre Doctors' Organisation

11. Ectopic pregnancy and miscarriage: diagnosis and initial management

and miscarriage: diagnosis and initial management (NG126) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 3 of 33This guideline replaces CG154. This guideline is the basis of QS69. Ov Overview erview This guideline covers diagnosing and managing ectopic pregnancy and miscarriage in women with complications, such as pain and bleeding, in early pregnancy (that is, up to 13 completed weeks of pregnancy). It aims to improve how (...) for an ultrasound scan Ectopic pregnancy and miscarriage: diagnosis and initial management (NG126) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 5 of 33what to expect during the course of her care (including expectant management), such as the potential length and extent of pain and/or bleeding, and possible side effects. This information should be tailored to the care she receives information about post-operative care

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

12. Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy

Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03008421 Recruitment Status : Not yet recruiting First Posted

2016 Clinical Trials

13. A case report of an asymptomatic late term abdominal pregnancy with a live birth at 41 weeks of gestation (PubMed)

A case report of an asymptomatic late term abdominal pregnancy with a live birth at 41 weeks of gestation Despite advances in diagnostic imaging and focused antenatal care, cases of undiagnosed abdominal pregnancies at term are still reported in obstetric practice. It is atypical and very rare for a patient to be asymptomatic late in pregnancy and for the pregnancy to result in a live birth with no evidence of intrauterine growth restriction despite the unfavourable implantation site (...) . This late term asymptomatic presentation despite routine antenatal care demonstrates a diagnostic challenge.We report a case of a 26 year old Primigravida with an asymptomatic and undiagnosed abdominal pregnancy carried beyond 41 weeks of gestation espite routine antenatal care and serial ultrasound reports. She presented for a routine antenatal care visit at 41 weeks of gestation. Induction of labour was initiated due to the late term gestation but was unsuccessful. At this point the fetus developed

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2016 BMC research notes

14. Laparoscopic cerclage for cervical incompetence to prevent late miscarriage or preterm birth

delivery. The condition is usually diagnosed after 1 or more late second trimester pregnancy losses or early third trimester delivery, and after other causes have been excluded. Current treatments 2.2 Cervical incompetence is traditionally treated by transvaginal cervical cerclage. This involves placing a strong suture or tape around the cervix, via the vagina, and tightening it to keep the cervix closed. The procedure is typically done at the end of the first trimester or the beginning of the second (...) trimester. The suture or tape is then usually removed at around 37 weeks of gestation to allow delivery. 2.3 Cervical cerclage using a transabdominal approach may be needed if transvaginal cerclage is technically difficult or has proved ineffective. With this approach, caesarean section is necessary to deliver the baby. The procedure 2.4 Laparoscopic cervical cerclage can be done during pregnancy or in women who Laparoscopic cerclage for cervical incompetence to prevent late miscarriage or preterm birth

2019 National Institute for Health and Clinical Excellence - Interventional Procedures

15. Overview of pregnancy complications

be complete, partial, or marginal, and may resolve as pregnancy progresses. Symptomatic placenta praevia typically presents as second or third trimester painless vaginal bleeding. Sakornbut E, Leeman L, Fontaine P. Late pregnancy bleeding. Am Fam Physician. 2007;75:1199-1206. http://www.aafp.org/afp/2007/0415/p1199.html http://www.ncbi.nlm.nih.gov/pubmed/17477103?tool=bestpractice.com Magann EF, Cummings JE, Niederhauser A, et al. Antepartum bleeding of unknown origin in the second half of pregnancy (...) :1115-1120. http://www.ncbi.nlm.nih.gov/pubmed/11846708?tool=bestpractice.com uterine scarring (e.g., due to prior caesarean section), Sakornbut E, Leeman L, Fontaine P. Late pregnancy bleeding. Am Fam Physician. 2007;75:1199-1206. http://www.aafp.org/afp/2007/0415/p1199.html http://www.ncbi.nlm.nih.gov/pubmed/17477103?tool=bestpractice.com multiple miscarriages, Kashanian M, Akbarian AR, Baradaran H, et al. Pregnancy outcome following a previous spontaneous abortion (miscarriage). Gynecol Obstet

2018 BMJ Best Practice

16. Overview of pregnancy complications

be complete, partial, or marginal, and may resolve as pregnancy progresses. Symptomatic placenta praevia typically presents as second or third trimester painless vaginal bleeding. Sakornbut E, Leeman L, Fontaine P. Late pregnancy bleeding. Am Fam Physician. 2007;75:1199-1206. http://www.aafp.org/afp/2007/0415/p1199.html http://www.ncbi.nlm.nih.gov/pubmed/17477103?tool=bestpractice.com Magann EF, Cummings JE, Niederhauser A, et al. Antepartum bleeding of unknown origin in the second half of pregnancy (...) :1115-1120. http://www.ncbi.nlm.nih.gov/pubmed/11846708?tool=bestpractice.com uterine scarring (e.g., due to prior caesarean section), Sakornbut E, Leeman L, Fontaine P. Late pregnancy bleeding. Am Fam Physician. 2007;75:1199-1206. http://www.aafp.org/afp/2007/0415/p1199.html http://www.ncbi.nlm.nih.gov/pubmed/17477103?tool=bestpractice.com multiple miscarriages, Kashanian M, Akbarian AR, Baradaran H, et al. Pregnancy outcome following a previous spontaneous abortion (miscarriage). Gynecol Obstet

2018 BMJ Best Practice

17. Management of Cardiovascular Diseases during Pregnancy

record a mean age between 28.8–31.2 years. The mild increase in maternal age does not justify an increase in CVD during pregnancy because of maternal age. However, pregnancies in the late reproductive years (or between ages of 40–50 years) are more frequently associated with an increasing prevalence of cardiovascular risk factors, especially diabetes, hypertension, and obesity. Additionally, an increasing number of women with congenital heart disease reach childbearing age. In western countries (...) Management of Cardiovascular Diseases during Pregnancy We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy | European Heart Journal | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter search input Article Navigation Close

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2018 European Society of Cardiology

18. Syphilis in pregnancy

primary, secondary and early latent stages). Consider the possibility of infectious syphilis if duration is unknown and there are no symptoms and/or no evidence of adequate treatment. Syphilis requiring treatment in pregnancy In this guideline, syphilis requiring treatment in pregnancy is used to mean infectious syphilis that is treated during the current pregnancy OR syphilis of unknown duration or late latent syphilis that is untreated, has been inadequately treated, or where there is no history (...) of adequate treatment and therefore requires treatment during this pregnancy. Late or limited antenatal care First presentation for antenatal care occurs in the third trimester, or the recommended antenatal testing and assessment is incomplete. Health care providers May include (but not limited to) neonatologist, paediatrician, social worker, Aboriginal and Torres Strait Islander health worker, infectious disease specialist, sexual health clinicians, public health unit personnel, general practitioner

2019 Queensland Health

19. Maternal, pregnancy and neonatal outcomes following IVF pregnancies

and/or cardiovascular parameters of children born after ART different than those born after naturally conceived pregnancies? Studies evaluating metabolic parameters of ART children have suggested that in late childhood, more peripheral body deposits are present compared to naturally conceived children. 78 Children with rapid weight MATERNAL, PREGNANCY AND NEONATAL OUTCOMES FOLLOWING IVF: A RAPID REVIEW | SAX INSTITUTE 18 gain in early childhood also had a higher chance of developing higher blood pressure. Overall (...) Maternal, pregnancy and neonatal outcomes following IVF pregnancies An Evidence Check rapid review brokered by the Sax Institute for NSW Kids and Families. June 2015. Maternal, pregnancy and neonatal outcomes following IVF pregnancies An Evidence Check rapid review brokered by the Sax Institute for NSW Kids and Families. June 2015. This report was prepared by: Christos A Venetis, Georgina M Chambers June 2015 © Sax Institute 2015 This work is copyright. It may be reproduced in whole or in part

2015 Sax Institute Evidence Check

20. Guidelines on autopsy practice: Fetal autopsy (2nd trimester fetal loss and termination of pregnancy for congenital anomaly)

losses (and if post-mortem examination had been carried out), malformation and growth restriction and other complications. · History of current pregnancy, including: estimated delivery date antenatal infection screen, including HIV abnormal findings from ultrasound or other antenatal investigations (copies of reports are helpful) hypertension/bleeding/pyrexia/membrane rupture events leading up to delivery for late miscarriages, live born or stillborn. [Level of evidence: GPP] 7 The autopsy procedure (...) that changes or significantly adds to the clinical diagnosis in nearly half of cases. 5,6 The autopsy is also a valuable audit of clinical care and may facilitate learning from adverse events. This guideline has been created to assist the pathologist undertaking autopsies in cases of second trimester (late) miscarriage, second trimester intrauterine death (missed miscarriage) and termination of pregnancy for fetal abnormality. It provides practical technical advice on performing the autopsy, guidance

2017 Royal College of Pathologists

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