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Laser Skin Procedure

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161. Exploring Laser-Induced Breakdown Spectroscopy as a Potential Tool in Mohs Micrography: A Mini Review (PubMed)

Exploring Laser-Induced Breakdown Spectroscopy as a Potential Tool in Mohs Micrography: A Mini Review Mohs micrographic surgery is the technique of surgically removing skin tumors by gradually excising thin layers and visualizing under a microscope till a tumor-free zone is obtained. During the surgical procedure, visible tumors are surgically removed. During the second stage, if tumor margins are clear with the positive specimen at depth, only depth cavitations need to be done without altering (...) the tumor diameter. Defining the depth during this procedure is a major challenge due to the nonexistence of proper guidelines. Using the laser-induced breakdown spectroscopy (LIBS) technique, depth profiling can be performed precisely, preventing excessive tissue removal and reducing time consumption during the microscopic examination.

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2017 Cureus

162. A Topical Anti-inflammatory Healing Regimen Utilizing Conjugated Linolenic Acid for Use Post-ablative Laser Resurfacing of the Face: A Randomized, Controlled Trial (PubMed)

regeneration. By modulating the early inflammatory milieu and directly affecting skin structure and function, conjugated linolenic acid might therefore shorten downtime following fractionated ablative laser resurfacing of the face. Objective: To evaluate the efficacy and subject satisfaction of a topical regimen containing conjugated linolenic acid derived from pomegranate seed extract in accelerating wound healing and improving skin quality following fractionated ablative laser resurfacing of the face (...) . Materials and Methods: Thirty-four subjects were enrolled and received fractionated CO2 laser resurfacing. Subjects were randomized to use the test healing regimen (n=24) or 1% dimethicone ointment (n=10) post-procedure. The primary endpoint was the degree of erythema, edema, crusting, and exudation evaluated by a blinded clinician at post-treatment Days 1,3,7,10, 14, and 30. Secondary endpoints included a blinded evaluator assessment of the degree of wrinkling and elastosis using the Fitzpatrick

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2017 The Journal of clinical and aesthetic dermatology Controlled trial quality: predicted high

163. Safety and Efficacy Evaluation of Pulsed Dye Laser Treatment, CO<sub>2</sub> Ablative Fractional Resurfacing, and Combined Treatment for Surgical Scar Clearance. (PubMed)

Safety and Efficacy Evaluation of Pulsed Dye Laser Treatment, CO2 Ablative Fractional Resurfacing, and Combined Treatment for Surgical Scar Clearance. Surgical scars are an unwanted sequela following surgical procedures. Several different treatment modalities and approaches are currently being employed to improve the cosmesis of surgical scars with each having varying degrees of success. The objective of this study was to assess the ef cacy and safety pulsed dye laser treatment, CO2 (...) ablative fractional resurfacing, and a combined treatment with these two modalities for the cosmetic improvement of surgical scarring that occurred following the surgical removal of skin cancer from different anatomic areas.Twenty-five patients with surgical scarring most frequently on the face following recent surgical excision of skin cancer with Mohs surgery were included in this multicenter, prospective clinical study. Patients were randomized into 4 treatment arms, namely, pulsed dye laser alone

2017 Journal of drugs in dermatology : JDD Controlled trial quality: uncertain

164. The Effects of Transcutaneous and Intraoral Low-Level Laser Therapy After Extraction of Lower Third Molars: A Randomized Single Blind, Placebo Controlled Dual-Center Study. (PubMed)

The Effects of Transcutaneous and Intraoral Low-Level Laser Therapy After Extraction of Lower Third Molars: A Randomized Single Blind, Placebo Controlled Dual-Center Study. The surgical removal of impacted third molars is one of the most common procedures performed by oral and maxillofacial surgeons. The purpose of this study is to determine whether either transcutaneous or intraoral low-level laser therapy (LLLT) reduces postoperative pain and assists in the healing of mandibular third molar (...) extraction.This randomized, placebo controlled, single-blind, split-mouth design study was conducted on 60 patients with full bony impacted similar position mandibular third molars bilaterally. The patients were divided into two groups of 30 each: transcutaneous LLLT and intraoral LLLT and the other side of each group treated with nonactive laser (60 teeth). The laser treatment consisted of administering laser energy immediately before and after the extraction procedure with gallium aluminum arsenide (GaAlAs

2017 Photomedicine and laser surgery Controlled trial quality: uncertain

165. Effect of Procedural-Related Variables on Melanocyte-Keratinocyte Suspension Transplantation in Nonsegmental Stable Vitiligo: A Clinical and Immunocytochemical Study. (PubMed)

with nonsegmental stable vitiligo. Donor site was either a skin graft in noncultured epidermal cell suspension (NCECS) or hair follicle units in outer root sheath hair follicle suspension (ORSHFS). Recipient site was prepared by either cryoblebbing or CO2 laser resurfacing. Cell counts and viability were recorded in the cell suspensions. Tissue melanocytes and keratinocytes were examined by melan-A and cytokeratin, respectively. Assessment of repigmentation was performed 18 months after the procedure.Thirty (...) Effect of Procedural-Related Variables on Melanocyte-Keratinocyte Suspension Transplantation in Nonsegmental Stable Vitiligo: A Clinical and Immunocytochemical Study. Melanocyte-keratinocyte suspension (M-K susp) is gaining popularity for vitiligo treatment. Few studies have addressed procedure-related variables.To assess the effect of different M-K susp procedure-related variables on the clinical outcome in stable vitiligo.This prospective multicenter comparative study included 40 cases

2017 Dermatologic Surgery

166. Genetics of Skin Cancer (PDQ®): Health Professional Version

Genetics of Skin Cancer (PDQ®): Health Professional Version Genetics of Skin Cancer (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): ; 2002 (...) -. Search term Genetics of Skin Cancer (PDQ®) Health Professional Version PDQ Cancer Genetics Editorial Board . Published online: February 14, 2019. Created: July 29, 2009 . This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the genetics of skin cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care

2016 PDQ - NCI's Comprehensive Cancer Database

167. Skin Cancer Treatment (PDQ®): Health Professional Version

do not become SCCs. These typically red, scaly patches usually arise on areas of chronically sun-exposed skin and are likely to be found on the face and dorsal aspects of the hand. Diagnostic and Staging Evaluation BCC and SCC are usually diagnosed on the basis of routine histopathology obtained from a shave, punch, incisional, or excisional biopsy.[ ] Other tests and procedures may be incorporated into the diagnosis and staging of BCC and SCC of the skin when appropriate and include (...) excision of facial BCCs in a randomized trial of primary BCCs.[ ] Mohs surgery. A surgical procedure to remove skin cancer in several steps. First, a thin layer of cancerous tissue is removed. Then, a second thin layer of tissue is removed and viewed under a microscope to check for cancer cells. More layers are removed one at a time until the tissue viewed under a microscope shows no remaining cancer. This type of surgery is used to remove as little normal tissue as possible and is often used to remove

2016 PDQ - NCI's Comprehensive Cancer Database

168. Skin Cancer Treatment (PDQ®): Patient Version

or liquid carbon dioxide to freeze and destroy abnormal tissue. : A surgical procedure that uses a beam (a narrow beam of intense light) as a knife to make bloodless cuts in tissue or to remove a surface such as a tumor. : Removal of the top layer of skin using a rotating wheel or small particles to rub away skin cells. Simple excision, Mohs micrographic surgery, curettage and electrodesiccation, and cryosurgery are used to treat basal cell carcinoma and squamous cell carcinoma of the skin. Laser (...) or procedures that examine the skin are used to detect (find) and diagnose basal cell carcinoma and squamous cell carcinoma of the skin. The following procedures may be used: and : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patient’s health habits and past illnesses and treatments will also be taken. Skin exam : An exam of the skin for bumps or spots that look in color, size, shape

2016 PDQ - NCI's Comprehensive Cancer Database

169. Immunohistological Evaluation of Skin Responses After Treatment Using a Fractional Ultrapulse Carbon Dioxide Laser on Back Skin. (PubMed)

Immunohistological Evaluation of Skin Responses After Treatment Using a Fractional Ultrapulse Carbon Dioxide Laser on Back Skin. Fractional photothermolysis (FP) lasers have been widely used in treating photo-aged skin, acne scars, and other skin conditions. Although plenty of clinical data have demonstrated the efficacy of the FP laser, only limited histologic studies have been available to observe serial short- to long-term skin responses.Seven healthy Chinese women received one pass (...) of fractional carbon dioxide laser treatment on the left upper back. Biopsies were taken at the baseline and 4 hours, 1 day, 5 days, 1 month, 3 months, 6 months, and 1 year after the procedure for hematoxylin and eosin stains, immunohistochemical evaluation (for heat shock proteins and elastin), and Verhoeff-iron-hematoxylin stains (for collagen and elastic fiber).Remarkably greater expression of heat shock protein (HSP)70 could be observed 4 hours after the procedure, which diminished significantly by 3

2011 Dermatologic Surgery

170. Single Treatment with 100-Microsecond Alexandrite Laser Clears Selected Acquired Melanocytic Nevi in Type IV Asian Facial Skin (PubMed)

Single Treatment with 100-Microsecond Alexandrite Laser Clears Selected Acquired Melanocytic Nevi in Type IV Asian Facial Skin Small common acquired melanocytic nevi (AMNs) are common on Asian facial skin.To show that the 755 nm Alexandrite laser stacked at the 100-μs long-pulsed mode (μsAL) is an effective modality for the removal of selected AMNs.This was a retrospective case series, followed up with a telephone interview.A retrospective analysis of all patients treated between January 2010 (...) and April 2012 with the μsAL laser for small AMNs was conducted. Pre- and post-treatment facial photographs and photographs of the individual lesions were analyzed by two independent dermatological surgeons for degree of clearance and complications. A telephone interview was conducted with the patients to assess their satisfaction with the procedure.A total of 18 patients with 53 lesions were included. 7/18 (38.9%) of patients had 'excellent' results. No patients had 'mild' or 'poor' results. At 4 week

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2013 Journal of cutaneous and aesthetic surgery

171. Efficacy of Long Pulsed 1064nm Laser for Facial Skin Tightening

Efficacy of Long Pulsed 1064nm Laser for Facial Skin Tightening Efficacy of Long Pulsed 1064nm Laser for Facial Skin Tightening - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Efficacy of Long Pulsed 1064nm (...) Laser for Facial Skin Tightening The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01971736 Recruitment Status : Completed First Posted : October 29, 2013 Last Update Posted : October 29, 2013 Sponsor: Phramongkutklao College of Medicine and Hospital Information provided by (Responsible Party

2013 Clinical Trials

172. Facial skin and soft tissue infection caused by Mycobacterium wolinskyi associated with cosmetic procedures. (PubMed)

(200 mg every 8 h), and ciprofloxacin (400 mg every 6 h).We report the first case of facial skin and soft tissue infection with M. wolinskyi after multiple cosmetic procedures of filler injection and laser lipolysis. Increased occurrence of NTM infection in nosocomial settings suggests the importance of appropriate treatment including culturing and rpoB gene sequencing when patients who have undergone cosmetic procedures display symptoms and signs of soft tissue infection indicative of NTM (...) Facial skin and soft tissue infection caused by Mycobacterium wolinskyi associated with cosmetic procedures. Mycobacteirum wolinskyi is a member of the Mycobacterium smegmatis group, which is less frequently found in clinical settings than other nontuberculous mycobacterium (NTM) species. However, its clinical significance has recently increased in opportunistic infections. This case is the first report of facial skin and soft tissue infection by M. wolinskyi complicating cosmetic procedures.A

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2013 BMC Infectious Diseases

173. Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy Volunteers

information Ages Eligible for Study: 55 Years and older (Adult, Older Adult) Sexes Eligible for Study: Female Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Age greater than or equal to 55 years Female All 4 grandparents of European descent Fitzpatrick Skin type 1-3 (fair skin type) Presence of moderate to severe fine wrinkling on arm skin Presence of moderate to severe dyspigmentation on arm skin Normal or overweight body mass index Exclusion Criteria: History of laser treatment or chemical (...) peels to to arm History of topical anti-aging products (includes retinol, tretinoin, tazarotene, azelaic acid, hydroquinone) to skin within 6 weeks of starting study History of surgical procedures to arm skin area including removal of benign or malignant skin cancers in the area of topical study agent application Current skin conditions in the area of arms including seborrheic keratosis, rosacea, eczema that may obscure study assessment History of abnormal scarring Uncontrolled medical problems

2017 Clinical Trials

174. Study to Assess the Cosmetic Changes in the Facial Skin After Use of a Topical Retinoid Product in Participants With Moderate to Severe Photodamage

, rosacea, skin cancer, etc.) Individuals who require electrolysis, waxing, or use depilatories on the face during the study Chemical peel or microdermabrasion within 4 weeks of study start Retin-A®, Retin-A Micro®, Renova®, Avita®,Tazorac®, Avage® or Differin® or other similar prescription drugs within 3 months of study start Cosmetic injections (filler and/or toxins, i.e. Juvederm, Radiesse, Botox, etc.), non-ablative laser or fractional laser resurfacing Accutane® or other oral retinoid, Ablative (...) procedures (i.e. laser, chemical, cosmetic surgeries) within 12 months of study start Participants who have planned surgeries or procedures. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03302559 Locations Layout table for location information United

2017 Clinical Trials

175. Brimonidine gel (Mirvaso): risk of systemic cardiovascular effects; not to be applied to damaged skin

. It is important to avoid application to irritated or damaged skin, including after laser therapy. Published 21 June 2017 From: Therapeutic area: , Advice for healthcare professionals: cases of bradycardia, hypotension (including orthostatic hypotension), and dizziness after application of brimonidine gel have been reported, some of which required hospitalisation some cases were associated with application of brimonidine gel after laser procedures to the skin, which possibly caused increased absorption (...) of the gel warn patients not to apply brimonidine gel to irritated or damaged skin, including after laser therapy to the skin Brimonidine (Mirvaso) is a topical gel indicated for the symptomatic treatment of facial erythema of rosacea in adults. It is an α-2 adrenergic agonist. A routine European review identified post-marketing reports, including a small number of Yellow Cards, consistent with systemic (central) α-2 adrenergic effects, including bradycardia, hypotension (including orthostatic

2017 MHRA Drug Safety Update

176. Blood Congestion Can Be Rescued by Hemodilution in a Random-Pattern Skin Flap. (PubMed)

subjected to a sham procedure. Subsequently, a random-pattern skin flap (1.5 × 6 cm) was elevated on the back of each rat. Physiologic assessments of flap vascularity/viability were performed using laser Doppler spectrophotometry before and after flap elevation.The normovolemic hemodilution group showed anemia (hemoglobin, 9.5 ± 0.8 g/dl) but less flow occlusion and greater flap survival (72.8 ± 8.6 percent) compared with control (57.4 ± 9.6 percent; p < 0.01) and blood transfusion (62.1 ± 6.5 percent (...) Blood Congestion Can Be Rescued by Hemodilution in a Random-Pattern Skin Flap. There is no standard method to ensure survival of random-pattern skin flaps. The authors developed a rat anemia model to observe survival of random-pattern skin flaps after blood transfusion and hemodilution.Anemia was induced by withdrawal of 35 percent blood volume followed by compensation with the same amount of blood (blood transfusion model) or plasma equivalent (normovolemic hemodilution). Control rats were

2017 Plastic and reconstructive surgery

177. Radio Frequency Microneedling for Suprapatellar Skin

procedures (e.g., laser or light treatments) for the treatment of wrinkles, skin resurfacing, or skin rejuvenation in the treatment area within 1 year of study participation. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03507036 Locations Layout table (...) of elastin. Additionally, as humans age, skin tends to appear more dry due to its poor hydration and turgor capacity. The use of minimally invasive aesthetic treatments in reducing signs of aging has been gaining in popularity over surgical treatments in recent years. Several energy types including, laser, radiofrequency, infrared, and ultrasound, have been developed for facial rejuvenation. These treatments induce controlled thermal damage into the dermis and cause collagen contraction

2017 Clinical Trials

178. Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity

contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03228641 Locations Layout table for location information United States, California Laser & Skin Center of Northern CA Sacramento, California, United States, 95816 United States, Massachusetts SkinCare Physicians Chestnut Hill, Massachusetts, United States, 02467 United States, New York Laser & Skin Surgery Center of NY New York, New (...) Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2017 Clinical Trials

179. VBeam Prima for Treatment of Photoaged Facial Skin

of ingesting medications known to induce photosensitivity, or history of seizure disorders due to light. Surgical, light-based therapy or RF procedures in the treatment area within 3 months of treatment or during the study. Any other surgery in the treated area within 3 months of treatment (or more if skin has not healed completely) or during the study. Tattoo or permanent make-up in the treated area. Systemica use of retinoids (i.e. Retin-A®, Accutane®) or antioxidants (i.e. Restylane®, Strivectin® (...) VBeam Prima for Treatment of Photoaged Facial Skin VBeam Prima for Treatment of Photoaged Facial Skin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. VBeam Prima for Treatment of Photoaged Facial Skin

2017 Clinical Trials

180. Efficacy of Micro-excisional Skin Removal by Micro-coring Device in Treatment of Wrinkles and Laxity of Face and Neck

days before treatment or during the study period Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03583918 Locations Layout table for location information United States, California Laser and Skin Surgery Center of Northern California Sacramento (...) , California, United States, 95816 United States, Florida Miami Dermatology and Laser Institute Miami, Florida, United States, 33173 United States, New York Laser and Skin Surgery Center of New York New York, New York, United States, 10016 United States, Tennessee The Practice of Brian S. Biesman, M.D Nashville, Tennessee, United States, 37203 United States, Texas Dr A Jay Burns Cosmetic Surgery Dallas, Texas, United States, 75231 Sponsors and Collaborators Cytrellis Biosystems, Inc. Investigators Layout

2017 Clinical Trials

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