How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

3,471 results for

Laser Skin Procedure

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

141. Fractional CO2 Laser Therapy for Survivors of Breast Malignancies

. Condition or disease Intervention/treatment Phase Breast Carcinoma Cancer Survivor Cervical Carcinoma Dyspareunia Vaginal Dryness Procedure: Laser Therapy Other: Questionnaire Administration Not Applicable Detailed Description: PRIMARY OBJECTIVES: I. To demonstrate the feasibility of fractionated CO2 laser treatments in patients with breast cancer with vaginal atrophy by determining treatment completion rates and tolerability of treatment. II. To demonstrate the efficacy of fractionated CO2 laser (...) Therapy for Survivors of Breast Malignancies Actual Study Start Date : November 15, 2017 Estimated Primary Completion Date : January 29, 2021 Estimated Study Completion Date : January 29, 2021 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Treatment (fractional CO2 laser therapy) Patients undergo fractional CO2 laser therapy every 4-6 weeks for 3 treatments. Procedure: Laser Therapy

2017 Clinical Trials

142. Evaluation of Safety of Low Level Laser Device Treatment in Chronic Wounds

will be used to treat the experimental group. Along with the active LLLT, generally accepted standard wound care procedures will be used during the clinical trial by a qualified study nurse or doctor. These procedures will include wound cleaning and drying before irradiation with the laser device (sham or active). Each ulcer will be also assessed and debrided if needed. After irradiation, each ulcer will be dressed with saline gauze dressing and offloaded. Sham Comparator: Control group The control group (...) Volunteers: No Criteria Inclusion Criteria: Provide signed and dated Informed Consent Form Willing to comply with all study procedures and be available for the duration of the study Male or female, aged 18 to 90 Having a DFU of at least 3 months duration that had not improved after prior standard wound treatments HbA1c of <11.0 Size of wounds: 1-10 cm2 Having DFU of grades 2 or 3 according to Wagner's classification Exclusion Criteria: Immeasurable wounds or wounds that are unsuited to this laser

2017 Clinical Trials

143. The Effect of Fractional Co2 Laser Either With Tacrolimus, Calcipotriol or NB-UVB in Stable Generalized Vitiligo

for skin resurfacing based on the theory of fractional photothermolysis introduced by Manstein et al (2004). These lasers were shown to be efficient in treating facial photo aging changes as well as scars, and have an improved safety and recovery profile compared with traditional CO2 laser resurfacing. Fractionated lasers do not ablate the entire epidermis and thereafter leave intact skin between coagulated necrotic columns. This characteristic facilitates the skin healing process (Bogdan et al., 2010 (...) The Effect of Fractional Co2 Laser Either With Tacrolimus, Calcipotriol or NB-UVB in Stable Generalized Vitiligo The Effect of Fractional Co2 Laser Either With Tacrolimus, Calcipotriol or NB-UVB in Stable Generalized Vitiligo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2017 Clinical Trials

144. Fractional Carbon Dioxide Laser,Topical Corticosteroid and Narrow Band Ultraviolet B in Treatment of Stable Vitiligo

in order to perform the procedures. Fractional carbon dioxide lasers, originally developed for tissue rejuvenation and scar remodeling. Recently, it has been used in the treatment of vitiligo. The newly developed fractional carbon dioxide laser does not ablate the entire epidermis, leaving intact skin between coagulated necrotic columns. It decreases risk of potential side effects and minimizes duration of sick leave. Several mechanisms may contribute to explain the improvement of Vitiligo after (...) . it is the most common depigmentation disorder, affecting approximately 0.5 to 2.0 percent of the population and has no predilection for gender or race . Condition or disease Intervention/treatment Phase Vitiligo Procedure: fractional carbon dioxide(CO2) laser Drug: Topical corticosteroid Radiation: Ultraviolet B narrow band Not Applicable Detailed Description: Vitiligo is primarily a clinical diagnosis without the need for diagnostic tools. It classified into three types: segmental vitiligo , nonsegmental

2017 Clinical Trials

145. Femtosecond Laser-assisted Corneal Debridement for Herpes Simplex Keratitis

, 2018 See Sponsor: Chunxiao Wang Information provided by (Responsible Party): Chunxiao Wang, Sun Yat-sen University Study Details Study Description Go to Brief Summary: The purpose of the study is to learn if adding femtosecond laser-assisted corneal debridement to a standard therapy of oral ganciclovir can help shorten the healing time of herpes simplex epithelial keratitis (HSK). Condition or disease Intervention/treatment Phase Herpes Simplex Keratitis Procedure: FLDEB Drug: Ganciclovir (GCV (...) : December 30, 2018 Estimated Study Completion Date : December 30, 2019 Resource links provided by the National Library of Medicine related topics: related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: FLDEB combined with GCV orally Femtosecond laser-assisted cornea debridement (FLDEB) combined with ganciclovir (GCV) orally. Procedure: FLDEB The eye will be anesthetized, and femtosecond laser technology will be used to remove epithelial tissue (diameter: 8mm

2017 Clinical Trials

146. Randomized Clinical Trial Evaluating the Use of the Laser-Assisted Immunotherapy (LIT/inCVAX) in Advanced Breast Cancer

Randomized Clinical Trial Evaluating the Use of the Laser-Assisted Immunotherapy (LIT/inCVAX) in Advanced Breast Cancer Randomized Clinical Trial Evaluating the Use of the Laser-Assisted Immunotherapy (LIT/inCVAX) in Advanced Breast Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Randomized Clinical Trial Evaluating the Use of the Laser-Assisted Immunotherapy (LIT/inCVAX) in Advanced Breast Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03202446 Recruitment Status : Terminated First

2017 Clinical Trials

147. Laser Acupuncture for Dry Eye

Study Description Go to Brief Summary: Subjects with dry eye are enrolled at two ophthalmic centers and randomly assigned to a laser acupuncture group and control group under conventional treatment with artificial tears. The effects of laser acupuncture therapy for patients with dry eye are investigated. Condition or disease Intervention/treatment Phase Dry Eye Procedure: Laser acupuncture Procedure: Sham laser acupuncture Not Applicable Detailed Description: Objective: Dry eye is a common (...) : July 31, 2019 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Laser acupuncture The subjects are treated at acupoints including BL2, TE23, ST2, LI4, ST36, and GB37 using laser acupuncture during 3 sessions per week for 12 weeks. Procedure: Laser acupuncture Subjects were treated 3 times per week for 12 weeks with the LaserPen (GaAlAs laser diode, 810 nm, 150 mW, pulsed waves), which delivered 0.375 J

2017 Clinical Trials

148. Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation

Gingival Hyperpigmentaion Drug: Ascorbic Acid 500 MG Device: diode laser Phase 4 Detailed Description: Cosmetic dentistry is usually centered on aesthetic restorative procedures but it may also involve the appearance of the gingiva, especially when it is located in the anterior labial region. Oral pigmentation may be physiological or pathological in nature. Better esthetics results of depigmentation were achieved with diode laser than conventional scalpel and with rotary abrasion, also diode laser (...) 17, 2017 Last Update Posted: August 22, 2017 Last Verified: August 2017 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Dalia Yosri, Ain Shams University: ascorbic acid diode laser gingival hyperpigmentation Additional relevant MeSH terms: Layout table for MeSH terms Hyperpigmentation Pigmentation Disorders Skin Diseases Ascorbic Acid Antioxidants Molecular Mechanisms of Pharmacological

2017 Clinical Trials

149. The Combination Therapy of Fractional Laser and PRP Compared With Nanofat Grafting and PRP Synergy in Treating Striae Gravidarum.

, microdermabrasion, platelet-rich plasma injection(PRP), etc. To some extent, these treatments can improve striae gravidarum. In this clinical trial, the investigators are going to treat striae gravidarum by using two different kinds of combination therapies. One is fractional laser and PRP injection synergy, and the other one is treated by nanofat grafting with PRP injection. Condition or disease Intervention/treatment Phase Treatments of Striae Gravidarum Device: Fractional CO2 Laser Procedure: Nanofat (...) grafting Procedure: Platelet-rich plasma (PRP) Injection Phase 3 Detailed Description: The investigators will pick out two areas of most severe striae gravidarum on a participant's abdomen. One of the areas will be treated by fractional laser once every three months for 2 times combined with PRP injection once a month for 6 times. Another area will be treated by nanofat grafting once every three months for 2 times and PRP therapy once a month for 6 times. The participants were asked to come back 1、3、6

2017 Clinical Trials

150. Pilot Study of the Ablative Fractional CO2 Laser in Hypertrophic Scars in Adult Burn Patients

Date : February 2015 Actual Primary Completion Date : May 2016 Actual Study Completion Date : December 2016 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Laser treated HSc scar Co2 laser treatment Procedure: Laser treatment CORE fractional CO2 laser treatment No Intervention: Control scar Standard care Outcome Measures Go to Primary Outcome Measures : Skin Characteristics changes (...) . Condition or disease Intervention/treatment Phase Burns Procedure: Laser treatment Not Applicable Detailed Description: Prior to treatment initiation, two independent scars sites will be selected and an anatomically- on each individual. At the selected treatment site the scar will be treated with the CORE fractional CO2 laser Participants will receive 3 treatment sessions scheduled 4 weeks apart. The scar sites will be evaluated at baseline, immediately before the 3rd treatment and 12 weeks after

2017 Clinical Trials

151. Pilot Study of Multi-wavelength Laser for Tattoo Removal

Pilot Study of Multi-wavelength Laser for Tattoo Removal Pilot Study of Multi-wavelength Laser for Tattoo Removal - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pilot Study of Multi-wavelength Laser (...) provided by (Responsible Party): Cutera Inc. Study Details Study Description Go to Brief Summary: To evaluate the safety and efficacy of an investigational version of the Cutera enLighten laser that offers muliple wavelengths for tattoo removal. Condition or disease Intervention/treatment Phase Tattoo Removal Device: Cutera enLighten laser Not Applicable Detailed Description: Currently, the enLighten laser offers two wavelengths: 532nm KTP and 1064nm Nd:YAG. The version of the laser under investigation

2017 Clinical Trials

152. Hybrid Fractional Laser for Symptoms of Genitourinary Syndrome of Menopause

) and 1470 nm diode lasers are cleared by the Food and Drug Administration (FDA) for ablation, vaporization, coagulation of soft tissue and for skin resurfacing. Fractional delivery of laser is a well-established method that stimulates tissue remodeling in the dermis while leaving the surrounding tissue intact in order to decrease healing time. The layers of skin and vaginal mucosal tissue exhibit similarities that suggest the clinical results seen with skin resurfacing may be translated to the vaginal (...) Hybrid Fractional Laser for Symptoms of Genitourinary Syndrome of Menopause Hybrid Fractional Laser for Symptoms of Genitourinary Syndrome of Menopause - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Hybrid

2017 Clinical Trials

153. Efficacy of 595 nm Pulsed-dye Laser in Treatment of Discoid Lupus Erythematosus

point Dose not undergo any procedure or laser treatment within 4 weeks before entered the study Dose not received any localised therapy of DLE eg. topical corticosteriod/immunomodulator within 4 weeks before entered the study Dose not receive the topical chemical peeling within 4 weeks before entered the study Has already received at least 1 systemic standard treatment for DLE and continue until the rest of the study Can follow the study's protocol Exclusion Criteria: Pregnancy or lactation History (...) Efficacy of 595 nm Pulsed-dye Laser in Treatment of Discoid Lupus Erythematosus Efficacy of 595 nm Pulsed-dye Laser in Treatment of Discoid Lupus Erythematosus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2017 Clinical Trials

154. Efficacy of Laser Debridement on Pain and Bacterial Load in Chronic Wounds

distress in patients with chronic wounds, in efforts to expedite the wound healing process. Condition or disease Intervention/treatment Phase Wound Open Chronic Venous Hypertension (Idiopathic) With Ulcer Diabetic Foot Ulcer Device: Erbium:Yttrium-Aluminum-Garnet (Er:YAG) Laser Debridement Procedure: Scalpel/Curette Debridement Not Applicable Detailed Description: Chronic wounds are a debilitating affliction, affecting a substantial portion of the population worldwide and incurring staggering (...) , lasers have been successfully utilized in many fields of medicine. Lasers for wound debridement began in the 1970s, with the successful report of a continuous-beam carbon dioxide (CO2) laser used for skin graft preparation of infected decubitus ulcers (11). Laser debridement is based on the controlled vaporization of the superficial layers of the wound bed. This results in the removal of the tissue containing unwanted microbial and necrotic particles. The laser type and the number of passes performed

2017 Clinical Trials

155. Comparison of the Effect of Vaseline and Bepanthen® "Wund- Und Heilsalbe" on the Wound Healing Following Laser Therapy

of a laser treatment are strongly determined by an appropriate treatment with special skin care products of the laser-treated skin. Cooling measures prevent the swelling of the treated skin area, if applied directly after the procedure. A soothing and wound-healing-promoting care applied subsequently for seven days, can support and also speed up the healing process. The Lumenis® Company is the manufacturer of CO2 laser systems and recommends the application of the Okklusiv ointment Vaseline® (...) First Posted : March 30, 2017 Last Update Posted : May 30, 2018 Sponsor: RWTH Aachen University Information provided by (Responsible Party): RWTH Aachen University Study Details Study Description Go to Brief Summary: In the field of dermatology the healing process and therefore the success of a laser treatment are strongly determined by an appropriate postoperative treatment of the laser-treated skin. The manufacturer of CO2 laser systems recommends the application of Vaseline postoperatively

2017 Clinical Trials

156. Hybrid Fractional Laser Treatment for Symptoms of Urinary Incontinence

are cleared by the Food and Drug Administration (FDA) for ablation, vaporization, coagulation of soft tissue and for skin resurfacing. Fractional delivery of laser is a well-established method that stimulates tissue remodeling in the dermis while leaving the surrounding tissue intact in order to decrease healing time. The layers of skin and vaginal mucosal tissue exhibit similarities that suggest the clinical results seen with skin resurfacing may be translated to the vaginal tissue. Improved vaginal (...) Hybrid Fractional Laser Treatment for Symptoms of Urinary Incontinence Hybrid Fractional Laser Treatment for Symptoms of Urinary Incontinence - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Hybrid

2017 Clinical Trials

157. Static and dynamic modes of 810 nm diode laser hair removal compared: A clinical and histological study (PubMed)

the static and dynamic laser depilation modes, nor in the severity of the pain experienced during the procedure. Histologically, degenerative changes in the hair follicles were noted immediately after laser treatment. At one month, cystic formation was seen in the hair follicles showing a strong tendency towards apoptotic cell death.With the diode laser system and at the parameters used in the present study, high depilation efficacy was seen with no significant difference between the static and dynamic (...) Static and dynamic modes of 810 nm diode laser hair removal compared: A clinical and histological study Laser hair removal has recently become a major indication. Diode lasers have become commercially available offering two modes of application: a stamping or static mode, and a dynamic mode whereby the handpiece is continuously moved across the target tissue. The present study was designed to compare the efficacy of these two approaches clinically and histologically.Twenty-five subjects

Full Text available with Trip Pro

2017 Laser therapy

158. A Case of Facial Partial Unilateral Lentiginosis Treated with Low-Fluence 1,064 nm Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser (PubMed)

A Case of Facial Partial Unilateral Lentiginosis Treated with Low-Fluence 1,064 nm Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal skin. Although treatment is not necessary, many patients with facial PUL seek medical help for cosmetic reasons. There is no established standard treatment for PUL. Conventional lasers may cause postinflammatory (...) proposed. If appropriate measures are taken to monitor patient response during and after the procedure, low-fluence 1,064-nm QS Nd:YAG laser may achieve good cosmetic results in the treatment of PUL with a very safe and effective profile.

Full Text available with Trip Pro

2017 Case reports in dermatology

159. Prostaglandin E1 Increases Microcirculation in Random Pattern Flaps on Rats Measured with Laser Doppler Perfusion Imaging (PubMed)

Prostaglandin E1 Increases Microcirculation in Random Pattern Flaps on Rats Measured with Laser Doppler Perfusion Imaging Reconstructive procedures with pedicled and free flaps are associated with a risk of ischemia. Prostaglandin E1 (PGE1) is a hormone-like substance with known antiischemic and tissue-protective effects. The aim of this study was to evaluate the effect of PGE1 on the microcirculation in random pattern skin flaps on rats.Twenty-four rats were divided into 2 groups (...) : an intervention group given PGE1 for 6 hours and a control group given saline. The flap (2 × 10 cm) was created on the back of the rats, and the microcirculation was monitored with laser Doppler perfusion imaging in 5 different zones (1, proximal; 5, distal) before surgery and after 60, 180, and 360 minutes postoperatively.Before surgery, there was no difference in the perfusion in any zones between the intervention group and the control group. The mean perfusion values in zone 1 in the intervention group

Full Text available with Trip Pro

2017 Plastic and Reconstructive Surgery Global Open

160. Stimulation Effect of Low Level Laser Therapy on Sciatic Nerve Regeneration in Rat (PubMed)

right side sciatic nerve was investigated. Twelve adult male Wistar rats underwent surgery in aseptic conditions under general anesthesia to induce a lesion to their right side sciatic nerve according to standard protocol. Before suturing the location, only the experimental group was treated by laser. The damaged nerve was directly irradiated with (2 J, 100 mW, 40 seconds). The irradiation procedure was terminated in 21 days with little improvement (4 J, 200 mW, 40 seconds) across the skin surface (...) Stimulation Effect of Low Level Laser Therapy on Sciatic Nerve Regeneration in Rat Introduction: Recent studies showed that low-level laser therapy (LLLT) accelerates the regeneration process of injured peripheral nerve tissue. The objective of this study was investigate the effect of LLLT (780 nm) on regeneration of injured right sciatic nerve of male Wistar rat. Methods: In this research work, the effect of LLLT (780 nm) on the regeneration process and reconstruction of injured peripheral

Full Text available with Trip Pro

2017 Journal of lasers in medical sciences

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>