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Laser Skin Procedure

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121. Platelet Rich Plasma, Complex Decongestive Physiotherapy and Low Level Laser in Treatment of Lower Extremity Lymphoedema

. This will be activated by the addition of platelet agonists such as thrombin, calcium gluconate or calcium chloride. Injections should be administered subcutaneously for 2-3 weeks, 3-4 times for inguinal, popliteal region and ankle for a total of 12 weeks. Also, all patients in this groups have received Complex Decongestive Physiotherapy (Manual lymph drainage (MLD), skin care, compression therapy and active therapeutic exercise). Experimental: Complex Decongestive Physiotherapy Procedure: Low Level Laser Low (...) for the inguinal region and the legs free in the abdomen.Also, all patients in this groups have received Complex Decongestive Physiotherapy (Manual lymph drainage (MLD), skin care, compression therapy and active therapeutic exercise). Experimental: Low Level Laser Procedure: Complex Decongestive Physiotherapy Complex Decongestive Physiotherapy (CDP) consists of four basic components and two phases. Four basic components; Manual lymph drainage (MLD), skin care, compression therapy and therapeutic exercise

2017 Clinical Trials

122. Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1

Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1 Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1 - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1 The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03090971 Recruitment Status : Completed First Posted : March 27, 2017 Last

2017 Clinical Trials

123. Administration of Low-level Laser on Muscles of Mastication Following the Induction of Initial Fatigue

: Active laser Three points on the masseter muscle (upper, middle and lower portions) and one point on the anterior temporal on each side of the face will be irradiated with a wavelength of 780 nm, radiant exposure of 134 J/cm2, power of 50 mW and irradiance of 1.675 W/cm2 for 80 seconds per point, resulting in an energy of 4 J per point and total energy of 32 J per volunteer.20,21 Point application will be performed with a conventional tip in contact with the skin (beam spot: 0.04 cm2). Radiation (...) : Active laser Three points on the masseter muscle (upper, middle and lower portions) and one point on the anterior temporal on each side of the face will be irradiated with a wavelength of 780 nm, radiant exposure of 134 J/cm2, power of 50 mW and irradiance of 1.675 W/cm2 for 80 seconds per point, resulting in an energy of 4 J per point and total energy of 32 J per volunteer.20,21 Point application will be performed with a conventional tip in contact with the skin (beam spot: 0.04 cm2). Sham

2017 Clinical Trials

124. Early Carbon Dioxide Laser Therapy for Alleviation of Incisional Scar Burden

at preventing scar formation after surgery.CO2 laser therapy is currently being used by dermatologists and plastic surgeons to help with scarring after acne and to rejuvenate the face; its benefits are now being explored by medical professionals in dermatology and cosmetic surgery to prevent scarring after surgery. Condition or disease Intervention/treatment Phase Skin Scarring Other: CO2 Laser Administration Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (...) breast reduction. Thus, for this study, only female patients will be considered (see below). Any patient enrolled in this study who shows evidence of delayed wound healing, dehiscence, or post operative infection at the first post operative visit will be excluded Patients with darker skin (Fitzpatrick IV and above), which is a well-known contraindication to laser therapy Pregnant patients Patients who have had prior breast surgery Patients who have had prior chest/breast irradiation Patients

2017 Clinical Trials

125. Fraxel Laser for Alopecia

of this procedure. Condition or disease Intervention/treatment Phase Alopecia Device: Fractional erbium-glass 1550 nm laser Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 20 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: A Pilot Study on 1550 nm Fractional Erbium-glass Laser for Alopecia Treatment Estimated Study Start Date : April 1, 2019 (...) Fraxel Laser for Alopecia Fraxel Laser for Alopecia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Fraxel Laser for Alopecia The safety and scientific validity of this study is the responsibility

2017 Clinical Trials

126. Opportunities for laser-assisted drug delivery in the treatment of cutaneous disorders. (PubMed)

Opportunities for laser-assisted drug delivery in the treatment of cutaneous disorders. Fractional laser-assisted drug delivery (LADD) is increasingly finding its way into clinical practice as a new means to enhance topical drug uptake and improve treatment of cutaneous disorders. To date, LADD has been used for a wide range of conditions, including photodamaged skin, neoplastic lesions, scars, cutaneous infections, and vitiligo as well as for topical anesthetic and aesthetic procedures (...) . Substantiated by randomized controlled clinical trials, strong evidence is available for LADD's usefulness for photodynamic therapy (PDT), for which improved efficacy using laser-assisted photosensitizer treatment is established for actinic keratosis compared with conventional PDT. Over time, the modality has undergone increasing refinement and offers the potential advantages of reduced treatment durations, shortened incubation times, and the replacement of cumbersome, patient-dependent treatment regimens

2017 Seminars in Cutaneous Medicine and Surgery

127. Advanced film-forming gel formula vs spring thermal water and white petrolatum as primary dressings after full face ablative fractional CO2 laser resurfacing: A comparative split-face pilot study. (PubMed)

-blinded, prospective observational study was to assess the efficacy and acceptability of two primary wound dressings immediately after a full-face fractional CO2 laser resurfacing procedure.The assessments of an innovative film-forming dressing called Stratacel (SC) vs spring thermal water + Vaseline (V+) were conducted after a standardized, single-pass, full-face ablative fractional CO2 laser skin resurfacing procedure. Clinical parameters, such as haemoglobin - HB; surface temperature - ST; micro (...) Advanced film-forming gel formula vs spring thermal water and white petrolatum as primary dressings after full face ablative fractional CO2 laser resurfacing: A comparative split-face pilot study. Aesthetically pleasing results and fast, uneventful recovery are highly desirable after rejuvenating ablative laser procedures. Wound dressings following ablative laser procedures should ideally improve and optimize the wound healing environment.The purpose of this comparative split-face, single

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2017 Journal of the European Academy of Dermatology and Venereology

128. A retrospective review of light- and laser-based management of hidradenitis suppurativa. (PubMed)

A retrospective review of light- and laser-based management of hidradenitis suppurativa. Hidradenitis suppurativa (HS) is a chronic skin disease that is difficult to manage and often refractory to medical management. Light and laser therapies have been utilized in the field of dermatology to treat a variety of skin conditions, but more recently were studied in the management of HS. Usually performed as outpatient procedures with a low risk of complications, they offer several advantages (...) to traditional cold knife surgical procedures. We reviewed the various light- and laser-based treatments studied in HS and compared their efficacy. Outcome measures were not standardized, which made comparison difficult. Studies performed were few in number and often limited by small patient samples. Larger, randomized controlled trials that compare these treatment modalities to medical and surgical management are needed. Despite their limitations, light- and laser-based therapies are promising treatment

2017 Seminars in Cutaneous Medicine and Surgery

129. Picosecond Laser Treatment for Tattoos and Benign Cutaneous Pigmented Lesions (Secondary publication) (PubMed)

lesions with less induction of post-inflammatory hyperpigmentation in the PIH-susceptible Asian skin, and dermal melanocytosis also respond very well to ps-laser treatment. Illustrative clinical examples from the author's experience are given.Current ps-lasers could be a revolutionary advance for laser tattoo removal but may be less effective for some specific aesthetic indications such as melasma and other cosmetic procedures. Manufacturers must make an effort to reduce the current comparatively long (...) Picosecond Laser Treatment for Tattoos and Benign Cutaneous Pigmented Lesions (Secondary publication) The selective removal of tattoos and benign cutaneous pigmented lesions with laser energy evolved rapidly with the development of the nanosecond-domain Q-switched laser (ns-laser). Recently, however, a series of picosecond-domain lasers (ps-lasers) with pulsewidths less than 1 ns has become commercially available, enabling more efficient and faster removal of pigmented lesions in the field

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2017 Laser therapy

130. Non-invasive Glucose Measurement Using Laser Technology

Non-invasive Glucose Measurement Using Laser Technology Non-invasive Glucose Measurement Using Laser Technology - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Non-invasive Glucose Measurement Using Laser (...) by (Responsible Party): Uzma Z Khan, University of Missouri-Columbia Study Details Study Description Go to Brief Summary: This study is to evaluate the capability of Raman spectroscopy as a non-invasive method for monitoring concentrations of glucose by illuminating a small spot on the skin, collecting and analyzing the return light. The glucose measurements obtained by Raman Spectroscopy are correlated with those obtained using YSI glucose analyzer and ACCUCHECK instruments. Condition or disease Intervention

2017 Clinical Trials

131. Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)

is an investigational (experimental) drug that works by helping participants' immune system work correctly to detect and fight cancer cells. Pembrolizumab is experimental because it is not approved by the Food and Drug Administration (FDA), for this use, though it is approved to treat other cancers. Condition or disease Intervention/treatment Phase Glioblastoma, Adult Drug: Pembrolizumab at 7 days prior Drug: Pembrolizumab at 14 days post Drug: Pembrolizumab at 35 days post Procedure: Laser Interstitial (...) : Pembrolizumab injections 7 days before surgery Patients will have intravenous pembrolizumab 7 days before surgery with Laser Interstitial Thermotherapy Drug: Pembrolizumab at 7 days prior Pembrolizumab injections 7 days before surgery Other Name: Pembrolizumab Procedure: Laser Interstitial Thermotherapy surgical procedure to heat hard to reach tumors with a laser beam Other Name: LITT Experimental: Pembrolizumab injections 14 days after surgery Patients will have intravenous pembrolizumab 14 days after

2017 Clinical Trials

132. Fractional Laser Assisted Delivery of Anesthetics IIIb

) Penetration of local anesthetics could be enhanced by pretreatment of the skin with ablative fractional lasers (AFXL) which locally disrupts the stratum corneum by creating an array of microscopic ablation channels. (Sklar, Burnett et al. 2014) In a previous pilot study, conducted at our institute, we demonstrated that effective anesthesia could be achieved within ten minutes after application of a topical anesthetic on skin pretreated with AFXL at painless settings. (Meesters, Bakker et al. 2015) However (...) will be given at unanesthetized skin. Subjects will be asked to indicate pain on a visual analogue scale (VAS) from 0-10 (0: no pain; 10: worst imaginable pain) directly after each pain stimulus Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 15 participants Allocation: Randomized Intervention Model: Factorial Assignment Masking: Single (Participant) Primary Purpose: Treatment Official Title: Parameters in Fractional Laser Assisted

2017 Clinical Trials

133. Efficacy of a Topical Anesthetic Containing Lidocaine and Prilocaine in Treatment With CO2 Fractional Laser

treatment is routinely used by plastic surgery and dermatology for treatment with aesthetic purposes of skin imperfections. It's a procedure until certain painful point, which as a rule is performed without prior use of topical anesthetic. The test product is believed to produce a clinically significant reduction of pain when compared to placebo, during the application of CO2 laser on the forehead for the aesthetic treatment of the face. Condition or disease Intervention/treatment Phase Lidocaine (...) in the forehead. In addition to efficacy, safety and tolerability of the product have been studied. The product under investigation is a topical formulation containing lidocaine 25 mg/g and prilocaine 25mg/g which in previous studies performed in the same institution with healthy subjects in adulthood showed faster onset than other formulations. In these previous studies, the product was well tolerated, and there were no signs of a skin reaction or adverse events of a systemic nature. The CO2 fractional laser

2017 Clinical Trials

134. Randomized CO2 vs Sham Laser Treatment of Provoked Vestibulodynia

is common. Fractional carbon-dioxide (CO2) laser is a technology widely used in dermatology for the treatment of various skin conditions. It has also been found to be an effective and safe treatment modality for symptoms of the genitourinary syndrome of menopause. A recent pilot study explored the use of fractional CO2 laser for the treatment of vestibulodynia in 37 subjects, 67.6% of which reported that their symptoms were "improved" or "very improved" after 3 fractional CO2 laser sessions. In addition (...) Treatment Fractional CO2 laser will be applied to the entire vestibule, anteriorly to the fourchette, and laterally to the labia majora. This takes approximately 5 minutes to complete. A treatment cycle will consist of three laser sessions separated by 6 weeks +/- 1 week. The procedures will take place in the outpatient clinic. EMLA cream will be applied to the introitus for 20 minutes and wiped clean and dried prior to each laser session. Subjects will be advised to avoid intercourse for at least 3

2017 Clinical Trials

135. Treatment of Atrofic Striae With Percutaneous Collagen Induction Therapy Versus Fractional Nonablative Laser

1340nm laser Device: Microneedling Not Applicable Detailed Description: Twenty patients will be treated at the dermatologic clinic of the Hospital de Clínicas de Porto Alegre (HCPA). Each patient will be treated with laser and microneedle at the same time, being applied a therapeutic procedure in each part of the abdomen (divided lengthwise and in equal parts). Each part of the abdomen will be randomized for the treatment of laser or microneedling with the help of the Excel 2013 program (...) . The investigator responsible for procedures and patients are the only ones with unblinded assessment in relation to the side of each treatment. There will be 5 sessions with monthly intervals of the proposed treatments. The ND-yap 1340-nm laser will be used, and in the other segment of the abdomen, the dermaroller 2.5 mm was applied. Photographic records of patients will be performed at pre-treatment and 1 month after the third and fifth sessions. The questionnaires will be applied to assess the quality

2017 Clinical Trials

136. Evaluation of Cutera Excel Vâ„¢ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment

attachment as assessed by frequency and severity (0=none, 1=mild, 2=moderate or 3=severe) of device adverse events as reported up to the 12 week follow-up visit. Measurement #3 of skin quality [ Time Frame: 2 to 4 weeks after third treatment and12 weeks post-final treatment ] Efficacy of the Cutera excel V laser with Green Genesis to diffuse facial redness and/or improve dyschromia (pigment) as compared to the Standard-of-Care (SOC) procedure using Excel V, as assessed by the study investigator at 2-4 (...) weeks after the 3rd laser treatment visit and at the 12 week follow-up visit, using Skin Quality Rating Scale (1-10): for Radiance, Smoothness, Pigmentation, Erythema and Pore size. Measurement #4 of wrinkles [ Time Frame: 2 to 4 weeks after third treatment and12 weeks post-final treatment ] Efficacy of the Cutera excel V laser with the Micro-Lens Array to treat fine lines and skin texture, as compared to the Standard-of-Care (SOC) procedure using Excel V, as assessed by the study investigator at 2

2017 Clinical Trials

137. Effect of LASER Photobiomodulation Therapy on Chronic Pain and Opioid Weaning

Study Completion Date : March 2019 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment ABAB Treatment, either LASER (arm A) or LOW LEVEL LASER (arm B) will be provided 3 (not less than 2) days a week for three weeks at which time crossover into the alternate arm occurs (BABA to ABAB or ABAB to BABA). ABAB initial period is active treatment - LASER. Active Treatment: LASER light is delivered to the skin and deeper tissues (...) affected by pain using either a wand or glass roller ball. Ten to 25 Watts of LASER energy is delivered to the painful regions for 8 to 16 minutes depending on the size of the area treated and other factors such as skin pigmentation. Device: LightForce EXPi LASER photobiomodulation therapy of 15-25 watts of coherent infrared light to affected area for 10 minutes using wand-type probe. Other Names: LASER photobiomodulation therapy LASER therapy BABA Treatment, either LASER (arm A) or LOW LEVEL LASER

2017 Clinical Trials

138. enLighten Laser With MLA Handpiece for Treatment of Moderate and Severe Acne Scars

handpiece attachment for the improvement of skin quality as assessed by the investigator and/or blinded evaluators 12-weeks-post final study treatment. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 42 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Other Official Title: Open-label, Prospective, Multicenter Study to Evaluate the Cutera enLighten™ Laser and a Micro-Lens Array (...) for Study: 18 Years to 65 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Subject must be able to read, understand and sign the Informed Consent Form. Female or Male, 18 to 65 years of age (inclusive). Fitzpatrick Skin Type I - VI (Appendix 6). Subject desires treatment for acne scars and wishes to undergo laser treatments for improvement. Subject has bilateral moderate to severe signs of facial acne scarring. Must be willing to have

2017 Clinical Trials

139. Fractional CO2 Laser Therapy for Survivors of Breast Malignancies

. Condition or disease Intervention/treatment Phase Breast Carcinoma Cancer Survivor Cervical Carcinoma Dyspareunia Vaginal Dryness Procedure: Laser Therapy Other: Questionnaire Administration Not Applicable Detailed Description: PRIMARY OBJECTIVES: I. To demonstrate the feasibility of fractionated CO2 laser treatments in patients with breast cancer with vaginal atrophy by determining treatment completion rates and tolerability of treatment. II. To demonstrate the efficacy of fractionated CO2 laser (...) Therapy for Survivors of Breast Malignancies Actual Study Start Date : November 15, 2017 Estimated Primary Completion Date : January 29, 2021 Estimated Study Completion Date : January 29, 2021 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Treatment (fractional CO2 laser therapy) Patients undergo fractional CO2 laser therapy every 4-6 weeks for 3 treatments. Procedure: Laser Therapy

2017 Clinical Trials

140. Evaluation of Safety of Low Level Laser Device Treatment in Chronic Wounds

will be used to treat the experimental group. Along with the active LLLT, generally accepted standard wound care procedures will be used during the clinical trial by a qualified study nurse or doctor. These procedures will include wound cleaning and drying before irradiation with the laser device (sham or active). Each ulcer will be also assessed and debrided if needed. After irradiation, each ulcer will be dressed with saline gauze dressing and offloaded. Sham Comparator: Control group The control group (...) Volunteers: No Criteria Inclusion Criteria: Provide signed and dated Informed Consent Form Willing to comply with all study procedures and be available for the duration of the study Male or female, aged 18 to 90 Having a DFU of at least 3 months duration that had not improved after prior standard wound treatments HbA1c of <11.0 Size of wounds: 1-10 cm2 Having DFU of grades 2 or 3 according to Wagner's classification Exclusion Criteria: Immeasurable wounds or wounds that are unsuited to this laser

2017 Clinical Trials

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