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Laser Skin Procedure

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61. The effect of human umbilical cord blood-derived mesenchymal stem cell media containing serum on recovery after laser treatment: A double-blinded, randomized, split-face controlled study. (Abstract)

The effect of human umbilical cord blood-derived mesenchymal stem cell media containing serum on recovery after laser treatment: A double-blinded, randomized, split-face controlled study. Ablative CO2 fractional laser (AFL) is a common cosmetic procedure to improve skin laxity. However, due to prolonged downtime and the risk of postinflammatory hyperpigmentation, laser-assisted delivery of active ingredients as post-laser treatment has gained interest in past years. Among various active (...) ingredients, human umbilical cord blood-derived mesenchymal stem cells (hUCBMSCs) can be a promising agent promoting skin regeneration.We evaluated the efficacy and safety of a human cord blood cell-conditioned media containing serum and cream on patients who underwent AFL treatment. A randomized, investigator-blinded, prospective, split-face comparison study was conducted.Twenty-three patients who underwent AFL on both cheeks applied a human umbilical cord blood-derived mesenchymal stem cell (hUCBMSC

2019 Journal of cosmetic dermatology Controlled trial quality: uncertain

62. Long-Term Assessment of Perioral Rhytide Correction with Erbium: YAG Laser Resurfacing. (Abstract)

Long-Term Assessment of Perioral Rhytide Correction with Erbium: YAG Laser Resurfacing. Use of nonsurgical skin rejuvenation has grown over the past two decades. This has led to an increase in ablative and nonablative resurfacing devices. Moderate to heavy perioral rhytides require an ablative laser to maximize results. Traditionally, this was performed with carbon dioxide lasers; however, more recently, erbium lasers have been used to target heavy rhytides. The purpose of this study (...) resurfacing is a powerful and safe tool for correcting perioral rhytides. It is effective in isolation or with other facial rejuvenation procedures. Erbium laser resurfacing is a useful adjunct in facial rejuvenation that can deliver exceptional results with few complications when performed within the proper guidelines.Therapeutic, IV.

2019 Plastic and reconstructive surgery

63. Endovascular Laser Treatment and Radiofrequency Ablation for Varicose Veins

for Varicose Veins Outcome Comparators RFA vs. Surgery RFA vs. ELT Postprocedural pain, minor complications RFA Surgery RFA ? ELT Patient preference RFA > Surgery RFA ? ELT Procedure costs RFA < Surgery RFA ~ ELT Budget impact RFA< Surgery RFA ~ ELT Abbreviations: ELT, endovascular laser ablation; QOL, quality of life; RFA, radiofrequency ablation. The outcomes of the evidence-based review on these treatments for VV based on different perspectives are summarized below: RFA First-generation Versus Second (...) Endovascular Laser Treatment and Radiofrequency Ablation for Varicose Veins OHTAC Recommendation: Endovascular Ablation for Varicose Veins Ontario Health Technology Advisory Committee July 2013 2 Background Health Quality Ontario (HQO) reviewed Endovascular Laser Therapy for Varicose Veins in April 2010 (http://www.health.gov.on.ca/english/providers/program/mas/tech/reviews/pdf/rev_EVLT_20100422.pdf) and Endovascular Radiofrequency Ablation for Varicose Veins in February 2011 (http

2013 Health Quality Ontario

64. Nd:YAG Laser for the Treatment of Patients with Hidradenitis Suppurativa

sinus; there is no universally accepted primary treatment for HS. 1 Surgical procedures, which are generally quite successful, are other treatment options for HS, however, they are associated with high morbidity. 2 Though generally used for hair removal, the neodymium:yttrium-aluminium-garnet (Nd:YAG) laser has recently shown promise for the treatment of HS lesions. The possible mechanism of action being follicular ablation and the destruction of inflammatory lesions through photothermolysis. 4 (...) chosen based on Fitzpatrick skin type. (Topical cooling gel used, no anesthetics). Co-treatment: 1% clindamycin gel 1% Clindamycin gel Adverse events, visual improvement of HS, disease severity (based on HS-LASI, but modified); patient satisfaction. Xu, 2011 3 To assess both the clinical and histopathological effects of Nd:YAG laser Hurley stage II disease, no concomitant systemic treatment, no stage III Long-pulsed 1064-nm Nd:YAG – single pulse for treatment area; double No treatment (topical

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

65. Laser hair removal for prevention of pilonidal sinus recurrence

Laser hair removal for prevention of pilonidal sinus recurrence Laser hair removal for prevention of pilonidal sinus recurrence Laser hair removal for prevention of pilonidal sinus recurrence Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Laser hair removal for prevention of pilonidal sinus recurrence. Lansdale: HAYES, Inc.. Healthcare Technology Brief (...) Publication. 2014 Authors' conclusions Pilonidal disease is a pathologic condition characterized by at least 1 abnormal pocket (sinus) or cyst located under the skin and filled with hair and skin debris. It is an acquired condition related to the presence of hair in the natal cleft, caused either by a reaction to loose hair that has penetrated and embedded in the skin or a reaction to a rupture of a hair follicle that may occur with stretching of the deep layers of skin or with the hormone-induced changes

2014 Health Technology Assessment (HTA) Database.

66. Effectiveness of a Nutraceutical During Non-Ablative 1927 nm Fractional Laser on Patients With Facial Hyperpigmentation and Photoaging. (Abstract)

Effectiveness of a Nutraceutical During Non-Ablative 1927 nm Fractional Laser on Patients With Facial Hyperpigmentation and Photoaging.

Background: Fractional lasers have been proven to treat hyperpigmentation and photoaging. Little research has been done on the effects of supplements on healing post-laser resurfacing. A nutraceutical could offer the benefit of faster healing of the skin and fewer side effects.

Objective: Evaluate the effectiveness of a nutraceutical associated (...) with fractional 1927 nm laser in healing time and effectiveness on hyperpigmentation and photoaging.

Methods & Materials: A prospective, randomized, evaluator-blinded, pilot study included Fitzpatrick skin types I-III patients with hyperpigmentation and photoaging randomly assigned to two groups. Group 1 was laser treatment and Group 2 was laser treatment and nutraceutical. Results were compared with objective biometric TEWL (transepidermal water loss), mexameter, corneometer, and cutometer parameters

2018 Journal of drugs in dermatology : JDD Controlled trial quality: uncertain

67. Evaluation of a non-ablative, fractional 1565 nm laser for the improvement of striae distensae albae. Full Text available with Trip Pro

appearance. POSAS patient total score declined from 33.5 points to 17.5 points throughout the study (P < 0.001). From baseline to 6-month FU, patients' life quality improved by 68.0% (DLQI score). Procedures showed no lasting negative side-effects and little to no down time.The use of a fractional non-ablative 1565 nm laser represents a safe approach for the treatment of SD albae. Clinically observed improvements were supported by significant data from objective measurements. The results achieved at 1 (...) Evaluation of a non-ablative, fractional 1565 nm laser for the improvement of striae distensae albae. Striae distensae (SD) represent therapeutically challenging forms of dermal atrophic scarring. In addition to topical ointments, medical needling and various energy-based devices, non-ablative fractional lasers have been suggested for their improvement. However, objective evaluations of their efficacy are widely missing. In this study, we aimed to assess the clinical improvement of SD albae

2018 Journal of the European Academy of Dermatology and Venereology

68. Validation of Laser Doppler Vibrometer (LDV) for Measurement of Arterial Stiffness in Hypertensive Patients

be a substitute for applanation tonometry. A laser Doppler vibrometer (LDV) is an instrument that is used to make non-contact vibration measurements of a surface. The laser beam from the LDV is directed at the surface of interest (in our case the skin covering the artery or the heart), and the vibration amplitude and frequency are extracted from the Doppler shift of the reflected laser beam frequency due to the motion of the surface. Preliminary data suggest that LDV can lead to an improved screening (...) stiffness without contact to the skin thanks to the LDV technique. The objective of this study is to compare the CARDIS LDV prototype with the reference techniques, carotid-femoral and local carotid PWV. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 100 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Other Official Title: Validation of Laser Doppler Vibrometer (LDV

2018 Clinical Trials

69. Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar

treatment areas that are 3 x 3cm with a 1cm wide segment of untreated scar between it. Surrounded by normal tissue For treatment areas surrounded by normal skin, the treatment area must be 33cm2 or greater, contain similar 3x3cm treatment areas, and have intervening segments of 1cm of scar between treatment areas. A border around the scar, is not required here because it is surrounded by normal skin. Exclusion Criteria: Previous laser or reconstructive procedures for the treatment of their HTBS (...) at improving scars by removing tissue without burning and injuring the surrounding tissue as the laser does. To evaluate these treatments (laser, punch biopsies, and no treatment), 3 small areas will be chosen in a study scar area that meets specific criteria to receive . Patients will still be able to receive laser and burn reconstruction procedures in all other areas not involving the study scar area that are clinically indicated. In the study, the scar will be evaluated with photographs, surveys

2018 Clinical Trials

70. Transperineal Laser Ablation for Treatment of Benign Prostatic Obstruction

vaporization. As these techniques enter the prostate via the urethra, are invasive and require general or spinal anaesthesia. Transperineal laser ablation (TPLA) is a minimal invasive procedure, that can be performed under local anaesthesia. Objective: The primary objective of this study is to prove feasibility and safety of TPLA for LUTS due to BPO in healthy men. Secondary objectives: The secondary objectives are to determine functional voiding, erectile outcomes and changes on imaging. Condition (...) this study by the urologist in the outpatient clinic. Information about the study will be provided both orally and in written form. The TPLA procedure is performed with the Echolaser X4 system. The system uses a diode laser source that operates at the 1064nm wavelength. The maximum energy delivered is 10 watts per laser source. The system works with the concept of thermoablation, resulting in coagulative necrosis of tissue. Two to four fibers are introduced in the prostate under untrasound vision

2018 Clinical Trials

71. MonaLisa Touch Laser for the Treatment of Vulvar Lichen Sclerosus

MonaLisa Touch Laser for the Treatment of Vulvar Lichen Sclerosus MonaLisa Touch Laser for the Treatment of Vulvar Lichen Sclerosus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. MonaLisa Touch Laser (...) for Vulvovaginal Disorders Collaborators: Gynecologic Cancer Research Foundation El. En. SpA Information provided by (Responsible Party): Center for Vulvovaginal Disorders Study Details Study Description Go to Brief Summary: Lichen sclerosus (LS) is a skin condition of the external genitals (vulva) of women. LS causes vulvar itching, pain, and burning. In addition, LS causes scarring of the vulva which may cause significant sexual dysfunction or pain. Lastly, 4-6% of women with LS will develop vulvar cancer

2018 Clinical Trials

72. Wave Propagation in Aluminum Honeycomb Plate and Debonding Detection Using Scanning Laser Vibrometer Full Text available with Trip Pro

Wave Propagation in Aluminum Honeycomb Plate and Debonding Detection Using Scanning Laser Vibrometer Both the aerospace and marine industry have widely relied on a honeycomb sandwich structure (HSS) because of its high strength-to-weight ratio. However, the intrinsic nature of an adhesively bonded multi-layer structure increases the risk of debonding when the structure is under strain or exposed to varying temperatures. Such defects are normally concealed under the surface but can significantly (...) compromise the strength and stiffness of a structure. In this paper, the guided wave method is used to detect debondings which are located between the skin and the honeycomb in sandwich plates. The propagation of guided waves in honeycomb plates is investigated via numerical techniques, with emphasis placed on demonstrating the behavior of structure-based wave interactions (SWIs). The SWI technique is effective to distinguish heterogeneous structures from homogeneous structures. The excitation frequency

2018 Sensors (Basel, Switzerland)

73. Fractional laser exposure induces neutrophil infiltration (N1 phenotype) into the tumor and stimulates systemic anti-tumor immune response. Full Text available with Trip Pro

Fractional laser exposure induces neutrophil infiltration (N1 phenotype) into the tumor and stimulates systemic anti-tumor immune response. Ablative fractional photothermolysis (aFP) using a CO2 laser generates multiple small diameter tissue lesions within the irradiation field. aFP is commonly used for a wide variety of dermatological indications, including treatment of photodamaged skin and dyschromia, drug delivery and modification of scars due to acne, surgical procedures and burns (...) . In this study we explore the utility of aFP for treating oncological indications, including induction of local tumor regression and inducing anti-tumor immunity, which is in marked contrast to current indications of aFP.We used a fractional CO2 laser to treat a tumor established by BALB/c colon carcinoma cell line (CT26.CL25), which expressed a tumor antigen, beta-galactosidase (beta-gal). aFP treated tumors grew significantly slower as compared to untreated controls. Complete remission after a single aFP

2017 PLoS ONE

74. Combination Versus Laser Treatment Only

-IV Has at least mild mottled skin tone of the face (score of 2 or more on a 5 point skin tone scale) Has at least 2 areas of the face with significant roughness, dyspigmentation, or fine lines or has all these characteristics in 1 or more areas Willing to refrain from using any other topical products on the face, systemic retinoids, or steroids, facial peels or other facial laser procedures throughout the duration of the study Willing to refrain from any cosmetic procedure including (...) Description Go to Brief Summary: Our objective is to determine the effects of (1) basic skin care regimen + "active" (Lytera 2.0) vs. (2) basic skin care regimen only, both groups combined with laser, on the appearance of skin tone and photo-aging on the face. Condition or disease Intervention/treatment Phase Photoaging Other: Skin Care Regimen plus Lytera 2.0 and Laser Therapy Other: Basic Skin Care Regimen Only and Laser Therapy Not Applicable Study Design Go to Layout table for study information Study

2018 Clinical Trials

75. Laser Therapy for At-Home Treatment of Diabetic Foot Ulcers

Laser Therapy for At-Home Treatment of Diabetic Foot Ulcers Laser Therapy for At-Home Treatment of Diabetic Foot Ulcers - Canada - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Laser Therapy for At-Home (...) Sponsor: Scarborough Rouge Hospital Information provided by (Responsible Party): Rose Raizman, Scarborough Rouge Hospital Study Details Study Description Go to Brief Summary: The global prevalence of diabetes is on the rise and with it increase in prevalence of diabetic foot ulcers (DFU). These recalcitrant wounds are difficult to manage and pose a heavy economic burden. Photobiomodulation (low level laser) is used for acceleration of wound healing. The current study is designed to evaluate

2018 Clinical Trials

76. Laser Therapy for At-Home Treatment of DIabetic Foot Ulcers

Carmel ltd: Photobiomodulation Low-Level Light Therapy Low-Level Laser Therapy Additional relevant MeSH terms: Layout table for MeSH terms Ulcer Diabetic Foot Foot Ulcer Pathologic Processes Diabetic Angiopathies Vascular Diseases Cardiovascular Diseases Leg Ulcer Skin Ulcer Skin Diseases Diabetes Complications Diabetes Mellitus Endocrine System Diseases Diabetic Neuropathies Foot Diseases (...) Laser Therapy for At-Home Treatment of DIabetic Foot Ulcers Laser Therapy for At-Home Treatment of DIabetic Foot Ulcers - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Laser Therapy for At-Home Treatment

2018 Clinical Trials

77. Evaluation of the New Laser PHOTOLASE PLV-585nm for the Treatment of Rosacea

with telangiectasia (visible and permanent dilatation of the small vessels). It frequently affects men and women with fair skin and can have significant psycho-emotional consequences. To counteract the unaesthetic appearance of redness and eliminate telangiectasia, the use of the laser is proposed to the patient. This study is a single center prospective, randomized, controlled split face study to compare 532nm KTP laser versus 585 nm PLV Laser in terms of improvement of the symptoms in the treatment (...) Consent Form Patient able to adhere to the program of visits of the study and the other imperatives of the protocol Patient accepting to have photographs taken on the face Quality of social insurance or social security entitlement Exclusion Criteria: Pregnant and/or breastfeeding woman or childbearing age without effective contraception Alcohol abuse assessed at the discretion of the investigator History of prior laser or light based procedures for any other pathology for the face within 6 months

2018 Clinical Trials

78. Sympathetic ganglionectomy for facial blushing using application of laser speckle flow graph. (Abstract)

Sympathetic ganglionectomy for facial blushing using application of laser speckle flow graph. Endoscopic thoracic sympathectomy at the second rib level is considered effective as a therapeutic treatment for facial blushing. However, 10% to 15% of patients do not benefit from this intervention. No additional procedure has been developed for this disorder. Recently, ganglionectomy using application of laser speckle flow graph has been evaluated for the treatment of compensatory sweating. We (...) report our results of ganglionectomy for facial blushing as a redo surgery.Between August 2012 and April 2017, 8 patients with facial blushing who underwent an initial sympathectomy reported symptom recurrence. Seven patients had undergone transection of the sympathetic trunk at the second rib and 1 patient had undergone transection of the sympathetic trunk at the second and third ribs. These patients were treated using ganglionectomy guided by application of laser speckle flow graph. After temporary

2018 Journal of Thoracic and Cardiovascular Surgery

79. Bimatoprost 0.03% Solution With NB-UVB Versus Their Use With Fractional Carbon Dioxide Laser in Treatment of Generalized Vitiligo

repigmentation) and perilesional active melanocytes (marginal repigmentation). In recent years, fractional carbon dioxide laser has been introduced as an add-on treatment for vitiligo. It represents a new modality for skin resurfacing based on the theory of fractional photothermolysis. The beneficial effect of fractional carbon dioxide laser on vitiligo is the release of cytokines and growth factors that act as mitogens for melanogenesis. It also alters the skin barrier, which results in increased (...) for 3 months + topical bimatoprost 0.03% solution twice daily ( 1 drop for each 2 cm2 ) and the other side will be treated by topical bimatoprost 0.03% twice daily ( 1 drop for each 2 cm2 ) + narrow band ultraviolet rays B sessions twice weekly for 3 months + 10.600-nm fractional carbon dioxide laser sessions twice monthly for 3 months. Patients' Evaluation: The recruited patients will be subjected to: A) Full history taking. B) General clinical examination. C) Dermatological examination of the skin

2018 Clinical Trials

80. Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors

breast tumors less than or equal to 15 mm will be invited to participate. Subjects will receive a screening MRI and if eligible will then have laser ablation, followed by MRI and an excision at 4-6 weeks following the laser procedure. This study will be deemed successful if the lower limit of a 95% confidence interval for the proportion of patients who have complete tumor ablation with one Novilase laser ablation procedure at 4-6 weeks post-procedure is greater than the performance goal. Specifically (...) a MRI and excision. Pathology and MRI will determine rate of complete ablation. Subject is expected to proceed with radiation and/or adjuvant therapy per standard of care. Device: Novilase Laser ablation Image-guided, percutaneous laser ablation of breast tumors Outcome Measures Go to Primary Outcome Measures : Percentage of target tumors completely ablated in one procedure [ Time Frame: 4-6 weeks ] Efficacy: Rate of complete ablation by Novilase laser ablation Frequency of adverse events

2018 Clinical Trials

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