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Laser Skin Procedure

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41. Laser Treatments in Early Wound Healing Improve Scar Appearance: -A Randomized Split-Wound Trial with Non-ablative Fractional Laser Exposures versus Untreated Controls. (PubMed)

Laser Treatments in Early Wound Healing Improve Scar Appearance: -A Randomized Split-Wound Trial with Non-ablative Fractional Laser Exposures versus Untreated Controls. In recent years, various lasers have increasingly been applied during wound healing to minimize scar formation. However, no consensus regarding treatment procedures exists.To assess scar formation clinically after three nonablative fractional laser (NAFL) exposures, targeting the inflammation, proliferation and remodelling wound (...) healing phases in patients vs. untreated controls.A randomized controlled trial was performed using a split-wound design to assess excisional wound halves treated with 1540-nm NAFL vs. no laser treatment. Three NAFL exposures were provided: immediately before surgery, at suture removal and 6 weeks after surgery. NAFL exposures were applied using two handpieces, sequentially distributing energy deeply and more superficially in the skin (40-50 mJ per microbeam). Evaluated at 3 months of follow-up

2018 British Journal of Dermatology Controlled trial quality: predicted high

42. Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin

Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin Comparative Effectiveness Review Number 199 Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin Evidence Summary Introduction Skin cancers, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common malignancies in the United States. 1 BCC and SCC, the 2 most common skin cancers, are collectively referred to as keratinocyte carcinomas. Over 5.4 million of these lesions are diagnosed (...) in 3.3 million people in the United States annually, 2, 3 and the global burden of disease from keratinocyte carcinomas is estimated at 12.9 disability- adjusted life years per 100,000 persons. 4 Generally keratinocyte carcinomas are not aggressive and do not metastasize or kill as often as melanoma, which is the third most common skin cancer. 5 However, SCC can metastasize and is estimated to kill between 3900 and 8800 people in the United States each year. 6 A more common problem is that BCC

2017 Effective Health Care Program (AHRQ)

43. Fractional CO2 laser treatment of vulvovaginal atrophy

. Fractional CO 2 laser treatment of VVA: October 2016 2 Technology, Company and Licensing Register ID WP251 Technology name Fractional CO 2 laser Patient indication For the treatment of vulvovaginal atrophy Description of the technology Fractional CO 2 laser technology consists of a non-surgical, laser-based treatment primarily for post-menopausal or post-partum vulvovaginal atrophy (VVA). 1 The procedure utilises a class four CO 2 laser, operating at 10,600 nm. The laser pulses for approximately one (...) millisecond, and is optically split to provide a fractionalised series of small ~200 micron dots. At the point of contact on the surrounding vaginal walls, the laser dot ablates a small area of tissue, and heats the tissue surrounding and deep to the ablation zone. 1, 2 Microablative fractional CO 2 lasers are currently used in dermatologic and plastic surgery skin applications to stimulate tissue remodelling. The process involves interaction between certain heat shock proteins, which induce a local

2016 COAG Health Council - Horizon Scanning Technology Briefs

44. Laser treatment is the preferred treatment for troublesome varicose veins

was more effective than foam treatment or surgery. Laser involved fewest complications six weeks after the procedure and may be the most cost effective option in the long term. Foam was the most cost effective option at six months and enabled the most rapid recovery but was less effective than laser or surgery. The NIHR funded CLASS trial results are in line with current NICE guidance to offer minimally invasive treatments in preference to surgery. A change in practice towards these treatments could (...) of the UK population have visible varicose veins, and in 2009/10 nearly 36,000 procedures were carried out by the NHS to treat varicose veins. Surgery to remove damaged sections of varicose veins is the longest-established treatment, but is costly and involves one to three weeks recovery. This study compared the effectiveness and quality of life improvements of two less invasive operations, foam and laser therapy, with surgery. What did this study do? The CLASS trial was carried out at 11 UK hospitals

2018 NIHR Dissemination Centre

45. Laser treatment is the preferred treatment for troublesome varicose veins

was more effective than foam treatment or surgery. Laser involved fewest complications six weeks after the procedure and may be the most cost effective option in the long term. Foam was the most cost effective option at six months and enabled the most rapid recovery but was less effective than laser or surgery. The NIHR funded CLASS trial results are in line with current NICE guidance to offer minimally invasive treatments in preference to surgery. A change in practice towards these treatments could (...) of the UK population have visible varicose veins, and in 2009/10 nearly 36,000 procedures were carried out by the NHS to treat varicose veins. Surgery to remove damaged sections of varicose veins is the longest-established treatment, but is costly and involves one to three weeks recovery. This study compared the effectiveness and quality of life improvements of two less invasive operations, foam and laser therapy, with surgery. What did this study do? The CLASS trial was carried out at 11 UK hospitals

2018 NIHR Dissemination Centre

46. Relationship of Skin Related SNP to Topical Skin Care Product

Retin-A®, Retin-A Micro®, Renova®, Avita®, Tazorac®, or Differin® within 2 weeks prior to the start of the study. Use of oral retinoids within 6 months of the study start. Subjects must not have had mid-depth or superficial chemical peel or other anti-aging procedures on the face (laser, intense pulsed light, injectable fillers microdermabrasion, etc.) within 2 months of the study start. Known allergies or sensitivities to test material ingredients or any topical skin care product (i.e., alpha (...) Relationship of Skin Related SNP to Topical Skin Care Product Relationship of Skin Related SNP to Topical Skin Care Product - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Relationship of Skin Related SNP

2018 Clinical Trials

47. Dynamic Optical Coherence Tomography(D-OCT) Aging Study: A Preliminary Evaluation of Structural Differences Between Young and Aged Skin, Cellulite and Atrophic Acne Scars in Female Caucasian Subjects With Fitzpatrick Skin Types I-III Utilizing Non-invasiv

. For standardization, this procedure will be performed with SkinMedica Facial Cleanser (to remove makeup and cleanse the face and thigh (if applicable)) for all the participants. Other Name: SkinMedica® Facial Cleanser Group B - Aged skin (55 - 75 years old) Assessments will be made after facial cleansing on areas being imaged utilizing VivoSight Dynamic Optical Coherence Tomography (D-OCT). Post-study D-OCT images will be processed with VivoSight software. Assessments of participant's overall photodamage (...) hepatitis, immune deficiency, or autoimmune. Individuals who have a pre-existing or dormant dermatologic condition (e.g. history of severe psoriasis, atopic dermatitis, rosacea, skin cancer, etc.) Individuals who have routinely used any of the following topical products, prescription products, or had any of the listed treatments/procedures within the listed time frame prior to study entry or will use during study: Any product that the investigator deems that could affect the study objectives

2018 Clinical Trials

48. Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy

the symptoms of VVA. The EdgeTM CO2 Laser and general fractional handpiece is approved by the FDA for ablative skin resurfacing (for example, treating fine lines and wrinkles, acne and surgical scars, skin pigmentation and discoloration, sun damage, pre-cancerous as well as benign lesions and uneven skin texture). The fractional handpiece used in this study for the treatment of VVA is experimental and has not been approved by the FDA for vaginal dryness associated with menopause. Study Design Go to Layout (...) Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2017 Clinical Trials

49. Laser Skin Procedure

Laser Skin Procedure Laser Skin Procedure Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Laser Skin Procedure Laser Skin Procedure (...) Aka: Laser Skin Procedure , CO2 Laser II. Indications s scars and wrinkles Scars Stretch marks Warts Vascular lesions Port wine stain Telangiectasia Pigmented lesions Cafe-au-lait Senile III. Advantages High cure rate IV. Disadvantages Slow healing Risk of painful scars Special equipment and Training Very Expensive! V. Precautions Use tight fitting mask and smoke evacuation equipment Prevents laryngeal Human papilloma virus Images: Related links to external sites (from Bing) These images

2015 FP Notebook

50. SimpliCT laser-guided needle placement in interventional radiology

SimpliCT laser-guided needle placement in interventional radiology SimpliCT laser-guided needle placement in SimpliCT laser-guided needle placement in interv interventional r entional radiology adiology Medtech innovation briefing Published: 7 March 2017 nice.org.uk/guidance/mib98 pathways Summary Summary The technology technology described in this briefing is SimpliCT. It is a laser device used to guide non- vascular puncture procedures in which CT or cone-beam CT imaging is used. The inno (...) observational studies; 2 prospective, non-comparative observational studies; and 1 case report. The studies include a total of 151 patients having interventional radiology, of whom 100 had a SimpliCT-guided procedure. These studies do not report any clinical- effectiveness outcomes. Comparative evidence shows that fluoroscopy time using cone-beam CT is reduced in non-vascular interventional procedures with SimpliCT laser guidance. However, comparative overall procedure time varies according to the clinical

2017 National Institute for Health and Clinical Excellence - Advice

51. Prospective comparison of recipient site preparation with fractional carbon dioxide (CO<sub>2</sub> ) laser versus dermabrasion and recipient site dressing composition in Melanocyte- Keratinocyte Transplantation Procedure (MKTP) in vitiligo: A preliminary (PubMed)

Prospective comparison of recipient site preparation with fractional carbon dioxide (CO2 ) laser versus dermabrasion and recipient site dressing composition in Melanocyte- Keratinocyte Transplantation Procedure (MKTP) in vitiligo: A preliminary 26409069 2017 03 06 2017 08 17 1365-2133 174 4 2016 Apr The British journal of dermatology Br. J. Dermatol. Prospective comparison of recipient-site preparation with fractional carbon dioxide laser vs. dermabrasion and recipient-site dressing (...) Study Evaluation Studies Letter 2016 01 24 England Br J Dermatol 0004041 0007-0963 IM Adult Aged Bandages Dermabrasion methods Female Humans Keratinocytes transplantation Laser Therapy methods Lasers, Gas Male Melanocytes transplantation Middle Aged Skin Pigmentation Skin Transplantation methods Treatment Outcome Vitiligo therapy Wound Closure Techniques Young Adult 2015 9 27 6 0 2015 9 27 6 0 2017 3 7 6 0 ppublish 26409069 10.1111/bjd.14204

2015 British Journal of Dermatology

52. Confocal Microscopy To Noninvasively Detect Skin Cancer: An Emerging Technology To Avoid Unnecessary Skin Biopsy

determine if a lesion is malignant or benign. A skin biopsy is a simple procedure performed by a physician and takes only a few minutes. In general, it is quick and easy for the physician. From the patient’s standpoint, however, undergoing a skin biopsy can be an unpleasant experience. A biopsy can be painful and leaves behind an unwanted scar. The results of the biopsy can take up to weeks, keeping the patient in a seemingly endless state of worrying, especially when melanoma is suspected. Additional (...) -frequency ultrasound, and magnetic resonance imaging. Confocal microscopy is the first imaging modality to offer single-cell resolution of the skin in vivo [4]. Confocal microscopy uses a focused laser beam to illuminate a specific point within the skin and measures the reflection of light from that point. Multiple points are scanned across an area parallel to the skin surface to construct a grayscale image. Various depths can also be imaged to form optical sections. Images can be produced with lateral

2013 Clinical Correlations

53. A systematic review into the methodologies used to document the impact of er: YAG laser on the skin and mucosa as well as its effects

A systematic review into the methodologies used to document the impact of er: YAG laser on the skin and mucosa as well as its effects Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne (...) and abstract, followed by full-text screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6

2018 PROSPERO

54. A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin

A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02385994 Recruitment Status : Completed First Posted : March 11, 2015 Last Update Posted : January 31

2015 Clinical Trials

55. Comparative Efficacy and Patient Preference of Topical Anaesthetics in Dermatological Laser Treatments and Skin Microneedling. (PubMed)

Comparative Efficacy and Patient Preference of Topical Anaesthetics in Dermatological Laser Treatments and Skin Microneedling. Topical anaesthetics are effective for patients undergoing superficial dermatological and laser procedures. Our objective was to compare the efficacy and patient preference of three commonly used topical anaesthetics: (2.5% lidocaine/2.5% prilocaine cream (EMLA(®)), 4% tetracaine gel (Ametop™) and 4% liposomal lidocaine gel (LMX4(®))) in patients undergoing laser (...) procedures and skin microneedling.This was a prospective, double-blind study of patients undergoing laser and skin microneedling procedures at a laser unit in a tertiary referral dermatology centre.All 29 patients had three topical anaesthetics applied under occlusion for 1 hour prior to the procedure, at different treatment sites within the same anatomical zone. A self-assessment numerical pain rating scale was given to each patient to rate the pain during the procedure and each patient was asked

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2015 Journal of cutaneous and aesthetic surgery Controlled trial quality: uncertain

56. Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure

reconstruction with deep inferior epigastric artery perforator flap. A greater understanding of the procedure's impact on the perfusion of the abdominal skin can be valuable in predicting areas susceptible to necrosis. Methods: Microcirculatory changes were monitored in the abdominal skin of 20 consecutive patients undergoing breast reconstruction with a deep inferior epigastric artery perforator flap. Quantitative mapping was performed with laser Doppler perfusion imaging at seven set intervals (...) Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2015 Clinical Trials

57. Long-Term Assessment of Perioral Rhytide Correction with Erbium: YAG Laser Resurfacing. (PubMed)

Long-Term Assessment of Perioral Rhytide Correction with Erbium: YAG Laser Resurfacing. Use of nonsurgical skin rejuvenation has grown over the past two decades. This has led to an increase in ablative and nonablative resurfacing devices. Moderate to heavy perioral rhytides require an ablative laser to maximize results. Traditionally, this was performed with carbon dioxide lasers; however, more recently, erbium lasers have been used to target heavy rhytides. The purpose of this study (...) resurfacing is a powerful and safe tool for correcting perioral rhytides. It is effective in isolation or with other facial rejuvenation procedures. Erbium laser resurfacing is a useful adjunct in facial rejuvenation that can deliver exceptional results with few complications when performed within the proper guidelines.Therapeutic, IV.

2019 Plastic and reconstructive surgery

58. Optical biopsy of penile cancer with in vivo confocal laser endomicroscopy. (PubMed)

healthy controls. Confocal laser endomicroscopy using a 2.6-mm fiber-optic probe was performed at 1 or 2 procedures on all subjects, for 13 imaging procedures. Fluorescein was administered intravenously approximately 3 minutes prior to imaging for contrast. Video sequences from in vivo (n = 12) and ex vivo (n = 6) imaging were obtained of normal glans, suspicious lesions, and surgical margins. Images were processed, annotated, characterized, and correlated with standard hematoxylin and eosin (...) histopathology.No adverse events related to imaging were reported. Distinguishing features of benign and malignant penile tissue could be identified by confocal laser endomicroscopy. Normal skin had cells of uniform size and shape, with distinct cytoplasmic membranes consistent with squamous epithelium. Malignant lesions were characterized by disorganized, crowded cells of various size and shape, lack of distinct cytoplasmic membranes, and hazy, moth-eaten appearance. The transition from normal to abnormal

2019 Urologic oncology

59. A systematic review of outcome reporting in laser treatments for dermatological diseases. (PubMed)

A systematic review of outcome reporting in laser treatments for dermatological diseases. The standardization of outcome reporting is crucial for interpretation and comparison of studies related to laser treatment of skin disorders. In collaboration with the Cochrane Skin-Core Outcome Set Initiative (CS-COUSIN), a procedure has been proposed to find consensus on the most important generic outcome domains (what to measure) for implementation in the international Laser TrEAtment in Dermatology (...) (LEAD) registry. As the first step in the development of a generic outcome set for the LEAD registry, we undertook a systematic review to identify outcomes, outcome measurement instruments, methods and definitions reported in recently published literature of laser treatments for skin disorders. A systematic search was conducted and generated a total of 707 papers. We assessed 150 studies including all types of studies involving laser treatments for the skin. Two researchers independently extracted

2019 Journal of the European Academy of Dermatology and Venereology

60. The effect of human umbilical cord blood-derived mesenchymal stem cell media containing serum on recovery after laser treatment: A double-blinded, randomized, split-face controlled study. (PubMed)

The effect of human umbilical cord blood-derived mesenchymal stem cell media containing serum on recovery after laser treatment: A double-blinded, randomized, split-face controlled study. Ablative CO2 fractional laser (AFL) is a common cosmetic procedure to improve skin laxity. However, due to prolonged downtime and the risk of postinflammatory hyperpigmentation, laser-assisted delivery of active ingredients as post-laser treatment has gained interest in past years. Among various active (...) ingredients, human umbilical cord blood-derived mesenchymal stem cells (hUCBMSCs) can be a promising agent promoting skin regeneration.We evaluated the efficacy and safety of a human cord blood cell-conditioned media containing serum and cream on patients who underwent AFL treatment. A randomized, investigator-blinded, prospective, split-face comparison study was conducted.Twenty-three patients who underwent AFL on both cheeks applied a human umbilical cord blood-derived mesenchymal stem cell (hUCBMSC

2019 Journal of cosmetic dermatology Controlled trial quality: uncertain

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