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41. VivaScope 1500 and 3000 imaging systems for detecting skin cancer lesions

squamous cell carcinoma. VivaScope 1500 and 3000 imaging systems for detecting skin cancer lesions (DG19) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 6 of 552 2 The technologies The technologies 2.1 The VivaScope 1500 and 3000 imaging systems (MAVIG) are non-invasive, high resolution, reflectance laser confocal microscope systems that are designed to help assess potentially malignant skin lesions. They aim (...) to provide quasi-histological resolution (a highly magnified image) of skin cells that is reportedly comparable to microscopic examination of a skin specimen. The VivaScope imaging systems are designed to be used with dermoscopy to help diagnose potentially malignant skin lesions, to delineate tumour margins for excision or to monitor healing after treatment. 2.2 The 2 CE-marked VivaScope imaging systems were identified during scoping as relevant to this assessment. No other commercially available laser

2015 National Institute for Health and Clinical Excellence - Diagnostics Guidance

42. Ionic Hydrogel Monotherapy and in Combination with Antiviral-Antibiotic Prophylaxis, in the Post-procedure Management of Fractional Laser-Treated Patients Full Text available with Trip Pro

Ionic Hydrogel Monotherapy and in Combination with Antiviral-Antibiotic Prophylaxis, in the Post-procedure Management of Fractional Laser-Treated Patients Objective: The pre- and postoperative care for fractionated laser resurfacing is still controversial, especially in regard to the use of antibiotics to prevent bacterial infection and potential consequences. Recently, an ionic hydrogel has shown to be useful in the postoperative treatment of minor burns. The aim of this study is to evaluate (...) the use of this hydrogel after fractional laser treatments targeting photoaging and chronoaging damage to skin. Design: A randomized prospective study. Setting: one plastic surgeon private practice. Participant: Fifty patients with chronoaging and photoaging cosmetic issues were enrolled in two different post-treatment regimens: ionic hydrogel alone and ionic hydrogel in combination with antibiotics. Measurements: Patients were evaluated for healing time, complications, and postoperative pain

2016 The Journal of clinical and aesthetic dermatology

43. Laser Skin Procedure

Laser Skin Procedure Laser Skin Procedure Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Laser Skin Procedure Laser Skin Procedure (...) Aka: Laser Skin Procedure , CO2 Laser II. Indications s scars and wrinkles Scars Stretch marks Warts Vascular lesions Port wine stain Telangiectasia Pigmented lesions Cafe-au-lait Senile III. Advantages High cure rate IV. Disadvantages Slow healing Risk of painful scars Special equipment and Training Very Expensive! V. Precautions Use tight fitting mask and smoke evacuation equipment Prevents laryngeal Human papilloma virus Images: Related links to external sites (from Bing) These images

2015 FP Notebook

44. Combination therapy in skin of color including injectables, laser, and light devices. Full Text available with Trip Pro

Combination therapy in skin of color including injectables, laser, and light devices. With the rapid increase in patients seeking cosmetic treatments, the variation in responses of lightly pigmented skin versus darkly pigmented skin has become increasingly apparent. Despite extensive treatment options in patients with skin of color, there is a paucity of well-designed studies performed on this patient population. The lack of research is concerning, as it is well documented that patients (...) with darker skin types are at an increased risk of adverse events when treated with many of the available modalities used in cosmetic procedures. Fortunately, by combining a variety of treatments, these risks may be abrogated, and combination treatments may be a promising regimen for a wide variety of cosmetic complaints. An overview and evaluation of the research of combination therapy in skin of color is presented.©2016 Frontline Medical Communications.

2016 Seminars in Cutaneous Medicine and Surgery

45. Efficiency of Carbon Dioxide Fractional Laser in Skin Resurfacing Full Text available with Trip Pro

Efficiency of Carbon Dioxide Fractional Laser in Skin Resurfacing The aim of the study was to confirm the efficiency and safety of the fractional CO2 laser in skin renewal and to check the possibility of having a synergistic effect in patients who besides carbon dioxide laser are treated with PRP (platelet-rich plasma) too.The first group (Examined Group 1 or EG1) included 107 patients treated with fractional CO2 laser (Lutronic eCO2) as mono-therapy. The second group (Control Group or CG (...) ) covered 100 patients treated with neither laser nor plasma in the same period but subjected to local therapy with drugs or other physio-procedures under the existing protocols for treatment of certain diseases. The third group (Examined Group 2 or EG2) treated 25 patients with combined therapy of CO2 laser and PRP in the treatment of facial rejuvenation or treatment of acne scars.Patient's satisfaction, in general, is significantly greater in both examined groups (EG1 and EG2) (p < 0.001

2016 Open access Macedonian journal of medical sciences Controlled trial quality: uncertain

46. Quantitative monitoring of laser-treated engineered skin using optical coherence tomography Full Text available with Trip Pro

Quantitative monitoring of laser-treated engineered skin using optical coherence tomography Nowadays, laser therapy is a common method for treating various dermatological troubles such as acne and wrinkles because of its efficient and immediate skin enhancement. Although laser treatment has become a routine procedure in medical and cosmetic fields, the prevention of side-effects, such as hyperpigmentation, redness and burning, still remains a critical issue that needs to be addressed. In order (...) to reduce the side-effects while attaining efficient therapeutic outcomes, it is essential to understand the light-skin interaction through evaluation of physiological changes before and after laser therapy. In this study, we introduce a quantitative tissue monitoring method based on optical coherence tomography (OCT) for the evaluation of tissue regeneration after laser irradiation. To create a skin injury model, we applied a fractional CO2 laser on a customized engineered skin model, which

2016 Biomedical optics express

47. Comparative study of wound healing in rat skin following incision with a novel picosecond infrared laser (PIRL) and different surgical modalities Full Text available with Trip Pro

Comparative study of wound healing in rat skin following incision with a novel picosecond infrared laser (PIRL) and different surgical modalities As a result of wound healing the original tissue is replaced by dysfunctional scar tissue. Reduced tissue damage during surgical procedures beneficially affects the size of the resulting scar and overall healing time. Thus the choice of a particular surgical instrument can have a significant influence on the postoperative wound healing. To overcome (...) these problems of wound healing we applied a novel picosecond infrared laser (PIRL) system to surgical incisions. Previous studies indicated that negligible thermal, acoustic, or ionization stress effects to the surrounding tissue results in a superior wound healing.Using the PIRL system as a surgical scalpel, we performed a prospective wound healing study on rat skin and assessed its final impact on scar formation compared to the electrosurgical device and cold steel. As for the incisions, 6 full-thickness

2016 Lasers in surgery and medicine

48. Study of a Novel Laser for Skin Rejuvenation

treatment to the target area within 6 months of study participation, such as laser or light-based procedures or surgery. Prior injection of botulinum toxin, collagen, hyaluronic acid filler or other dermal filler within 6 months of study participation. History of malignant tumors in the target area. Skin abnormalities in the target area, e.g., cuts, scrapes, wounds, large moles. Pregnant and/or breastfeeding. Having an infection, dermatitis or a rash in the treatment area. Significant concurrent illness (...) Study of a Novel Laser for Skin Rejuvenation Study of a Novel Laser for Skin Rejuvenation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of a Novel Laser for Skin Rejuvenation The safety

2016 Clinical Trials

49. Comparison of the Efficacy of Micro-holes vs. Laser-assisted Dermabrasion, for Repigmenting in Vitiligo Skin

Comparison of the Efficacy of Micro-holes vs. Laser-assisted Dermabrasion, for Repigmenting in Vitiligo Skin Comparison of the Efficacy of Micro-holes vs. Laser-assisted Dermabrasion, for Repigmenting in Vitiligo Skin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Comparison of the Efficacy of Micro-holes vs. Laser-assisted Dermabrasion, for Repigmenting in Vitiligo Skin (Dermabrasion) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02660320 Recruitment Status : Active, not recruiting First Posted

2016 Clinical Trials

50. Histological Study to Evaluate Skin Changes After PicoWay® 1064 nm and 532nm Picosecond Fractional Laser Treatment

, skin peeling and skin surface roughness. A laser procedure, a peel or has used lightening creams that was performed in the area to be treated with the past six months History of immunosuppression/immune deficiency disorders (including HIV infection or AIDS) or currently using immunosuppressive medications Known allergy to lidocaine, tetracaine, Xylocaine or epinephrine Subjects with pigmented lesions that are considered not acceptable by the study investigator or any condition (...) Histological Study to Evaluate Skin Changes After PicoWay® 1064 nm and 532nm Picosecond Fractional Laser Treatment Histological Study to Evaluate Skin Changes After PicoWay® 1064 nm and 532nm Picosecond Fractional Laser Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2016 Clinical Trials

51. Prospective comparison of recipient site preparation with fractional carbon dioxide (CO<sub>2</sub> ) laser versus dermabrasion and recipient site dressing composition in Melanocyte- Keratinocyte Transplantation Procedure (MKTP) in vitiligo: A preliminary (Abstract)

Prospective comparison of recipient site preparation with fractional carbon dioxide (CO2 ) laser versus dermabrasion and recipient site dressing composition in Melanocyte- Keratinocyte Transplantation Procedure (MKTP) in vitiligo: A preliminary 26409069 2017 03 06 2017 08 17 1365-2133 174 4 2016 Apr The British journal of dermatology Br. J. Dermatol. Prospective comparison of recipient-site preparation with fractional carbon dioxide laser vs. dermabrasion and recipient-site dressing (...) Study Evaluation Studies Letter 2016 01 24 England Br J Dermatol 0004041 0007-0963 IM Adult Aged Bandages Dermabrasion methods Female Humans Keratinocytes transplantation Laser Therapy methods Lasers, Gas Male Melanocytes transplantation Middle Aged Skin Pigmentation Skin Transplantation methods Treatment Outcome Vitiligo therapy Wound Closure Techniques Young Adult 2015 9 27 6 0 2015 9 27 6 0 2017 3 7 6 0 ppublish 26409069 10.1111/bjd.14204

2015 British Journal of Dermatology

52. Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy

the symptoms of VVA. The EdgeTM CO2 Laser and general fractional handpiece is approved by the FDA for ablative skin resurfacing (for example, treating fine lines and wrinkles, acne and surgical scars, skin pigmentation and discoloration, sun damage, pre-cancerous as well as benign lesions and uneven skin texture). The fractional handpiece used in this study for the treatment of VVA is experimental and has not been approved by the FDA for vaginal dryness associated with menopause. Study Design Go to Layout (...) Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2017 Clinical Trials

53. A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin

A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian Skin The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02385994 Recruitment Status : Completed First Posted : March 11, 2015 Last Update Posted : January 31

2015 Clinical Trials

54. Comparative Efficacy and Patient Preference of Topical Anaesthetics in Dermatological Laser Treatments and Skin Microneedling. Full Text available with Trip Pro

Comparative Efficacy and Patient Preference of Topical Anaesthetics in Dermatological Laser Treatments and Skin Microneedling. Topical anaesthetics are effective for patients undergoing superficial dermatological and laser procedures. Our objective was to compare the efficacy and patient preference of three commonly used topical anaesthetics: (2.5% lidocaine/2.5% prilocaine cream (EMLA(®)), 4% tetracaine gel (Ametop™) and 4% liposomal lidocaine gel (LMX4(®))) in patients undergoing laser (...) procedures and skin microneedling.This was a prospective, double-blind study of patients undergoing laser and skin microneedling procedures at a laser unit in a tertiary referral dermatology centre.All 29 patients had three topical anaesthetics applied under occlusion for 1 hour prior to the procedure, at different treatment sites within the same anatomical zone. A self-assessment numerical pain rating scale was given to each patient to rate the pain during the procedure and each patient was asked

2015 Journal of cutaneous and aesthetic surgery Controlled trial quality: uncertain

55. Confocal Microscopy To Noninvasively Detect Skin Cancer: An Emerging Technology To Avoid Unnecessary Skin Biopsy

determine if a lesion is malignant or benign. A skin biopsy is a simple procedure performed by a physician and takes only a few minutes. In general, it is quick and easy for the physician. From the patient’s standpoint, however, undergoing a skin biopsy can be an unpleasant experience. A biopsy can be painful and leaves behind an unwanted scar. The results of the biopsy can take up to weeks, keeping the patient in a seemingly endless state of worrying, especially when melanoma is suspected. Additional (...) -frequency ultrasound, and magnetic resonance imaging. Confocal microscopy is the first imaging modality to offer single-cell resolution of the skin in vivo [4]. Confocal microscopy uses a focused laser beam to illuminate a specific point within the skin and measures the reflection of light from that point. Multiple points are scanned across an area parallel to the skin surface to construct a grayscale image. Various depths can also be imaged to form optical sections. Images can be produced with lateral

2013 Clinical Correlations

56. Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure

reconstruction with deep inferior epigastric artery perforator flap. A greater understanding of the procedure's impact on the perfusion of the abdominal skin can be valuable in predicting areas susceptible to necrosis. Methods: Microcirculatory changes were monitored in the abdominal skin of 20 consecutive patients undergoing breast reconstruction with a deep inferior epigastric artery perforator flap. Quantitative mapping was performed with laser Doppler perfusion imaging at seven set intervals (...) Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2015 Clinical Trials

57. Fractional CO2 laser treatment of vulvovaginal atrophy

. Fractional CO 2 laser treatment of VVA: October 2016 2 Technology, Company and Licensing Register ID WP251 Technology name Fractional CO 2 laser Patient indication For the treatment of vulvovaginal atrophy Description of the technology Fractional CO 2 laser technology consists of a non-surgical, laser-based treatment primarily for post-menopausal or post-partum vulvovaginal atrophy (VVA). 1 The procedure utilises a class four CO 2 laser, operating at 10,600 nm. The laser pulses for approximately one (...) millisecond, and is optically split to provide a fractionalised series of small ~200 micron dots. At the point of contact on the surrounding vaginal walls, the laser dot ablates a small area of tissue, and heats the tissue surrounding and deep to the ablation zone. 1, 2 Microablative fractional CO 2 lasers are currently used in dermatologic and plastic surgery skin applications to stimulate tissue remodelling. The process involves interaction between certain heat shock proteins, which induce a local

2016 COAG Health Council - Horizon Scanning Technology Briefs

58. Genetics of Skin Cancer (PDQ®): Health Professional Version

Genetics of Skin Cancer (PDQ®): Health Professional Version Genetics of Skin Cancer (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): ; 2002 (...) -. Search term Genetics of Skin Cancer (PDQ®) Health Professional Version PDQ Cancer Genetics Editorial Board . Published online: January 3, 2020. Created: July 29, 2009 . This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the genetics of skin cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care

2018 PDQ - NCI's Comprehensive Cancer Database

59. Skin Cancer Treatment (PDQ®): Patient Version

or procedures that examine the skin are used to detect (find) and diagnose basal cell carcinoma and squamous cell carcinoma of the skin. The following procedures may be used: and : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patient’s health habits and past illnesses and treatments will also be taken. Skin exam : An exam of the skin for bumps or spots that look in color, size, shape (...) . The following tests and procedures may be used in the staging process for squamous cell carcinoma of the skin: (CAT scan) : A procedure that makes a series of detailed pictures of areas inside the body, such as the head, neck, and chest, taken from different angles. The pictures are made by a computer linked to an machine. A may be into a or swallowed to help the or show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography. : An x-ray

2018 PDQ - NCI's Comprehensive Cancer Database

60. Optical biopsy of penile cancer with in vivo confocal laser endomicroscopy. (Abstract)

healthy controls. Confocal laser endomicroscopy using a 2.6-mm fiber-optic probe was performed at 1 or 2 procedures on all subjects, for 13 imaging procedures. Fluorescein was administered intravenously approximately 3 minutes prior to imaging for contrast. Video sequences from in vivo (n = 12) and ex vivo (n = 6) imaging were obtained of normal glans, suspicious lesions, and surgical margins. Images were processed, annotated, characterized, and correlated with standard hematoxylin and eosin (...) histopathology.No adverse events related to imaging were reported. Distinguishing features of benign and malignant penile tissue could be identified by confocal laser endomicroscopy. Normal skin had cells of uniform size and shape, with distinct cytoplasmic membranes consistent with squamous epithelium. Malignant lesions were characterized by disorganized, crowded cells of various size and shape, lack of distinct cytoplasmic membranes, and hazy, moth-eaten appearance. The transition from normal to abnormal

2019 Urologic oncology

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