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21. Fragility of epidermis: acne and post-procedure lesional skin. Full Text available with Trip Pro

in restoration of fragile skin caused by the acne topical retinoid treatment adapalene 0.1% gel, by reducing transepidermal water loss and improving skin hydration, as well as reducing the side-effects such as skin irritation that are frequently associated with topical retinoids. Additionally, dermo-cosmetic products were found to accelerate wound closure following skin damage in a laser ablation model and reduced the duration of post-procedural side-effects such as itching and burning.© 2017 European (...) Fragility of epidermis: acne and post-procedure lesional skin. 'Fragile skin', or skin with lower resistance to aggressors, can be broadly classified into four causal categories: constitutional (age-dependent or associated with specific vulnerable locations on the body, e.g. eyelids), pathological (related to disease), circumstantial (related to environmental or internal factors, e.g. stress) and iatrogenic (caused by medical interventions or treatments). In this supplement, we focus

2017 Journal of the European Academy of Dermatology and Venereology Controlled trial quality: uncertain

22. Interventions for ulceration and other skin changes caused by nerve damage in leprosy. (Abstract)

existing ulcers, one of them also evaluated prevention of new ulcers. One study aimed to prevent skin changes, such as cracking and fissures. Investigated interventions included: laser therapy, light-emitting diode (LED), zinc tape, intralesional pentoxifylline, pulsed magnetic fields, wax therapy, ketanserin, human amniotic membrane gel, phenytoin, plaster shoes, and footwear.We are uncertain about the following key results, as the certainty of evidence is very low. All time points were measured from (...) Interventions for ulceration and other skin changes caused by nerve damage in leprosy. At the end of 2016, 145 countries reported to the World Health Organization (WHO) over 173,000 new cases of leprosy worldwide. In the past 20 years, over 16 million people have been treated for leprosy globally. The condition's main complications are injuries and ulceration caused by sensory loss from nerve damage. In this review we explored interventions to prevent or treat secondary damage to the skin

2019 Cochrane

23. Ablative fractional laser resurfacing for burn scar treatment

of efficacy and safety data across burn and non-burn scars if that would help interpret these results. MSAC advised that any resubmission would need to be considered by ESC. 3. Summary of consideration and rationale for MSAC’s advice MSAC noted that laser scar treatment works on the basis of remodelling skin by creating microscopic photo-thermal injury (thermolysis) to specific target scarred skin areas. Most patients receive a series of three to six CO 2 AFL procedures, at a minimum treatment interval (...) ) listing of carbon dioxide ablative fractional laser (CO 2 AFL) resurfacing for burn scar treatment was received from Burns Unit of Concord Repatriation General Hospital (CRGH) by the Department of Health. Laser scar treatment works on the basis of remodelling skin by creating microscopic photo- thermal injury (‘thermolysis’) to specific target scarred skin areas. Skin remodelling from thermolysis following laser treatment shares the same features as wound repair and skin morphogenesis. 2. MSAC’s

2018 Medical Services Advisory Committee

24. Endoscopic Epidural Laser Decompression Versus Transforaminal Epiduroscopic Laser Annuloplasty for Lumbar Disc Herniation: A Prospective, Randomized Trial (Abstract)

Endoscopic Epidural Laser Decompression Versus Transforaminal Epiduroscopic Laser Annuloplasty for Lumbar Disc Herniation: A Prospective, Randomized Trial Lumbar radicular pain often results from lumbar disc herniation, spinal stenosis, or degenerative spondylolisthesis. Minimally invasive disc decompression procedures, such as nucleo-annuloplasty or epiduroscopic neural decompression by laser, have been devised to treat such pain.The short-term outcomes of disc decompression by endoscopic (...) epidural laser decompression (EELD) or transforaminal epiduroscopic laser annuloplasty (TELA) were compared in patients with lumbar radicular pain due to disc herniation.A randomized, prospective trial.The Department of Anesthesiology and Pain Medicine at Spine Health Wooridul Hospital in Daegu, Korea.A total of 97 patients were enrolled in this study; 48 patients underwent EELD and 49 underwent TELA. The pain relief was evaluated at baseline and at 1, 3, and 6 months post-procedure via the numeric

2018 EvidenceUpdates

25. Adult and Pediatric Antibiotic Prophylaxis during Vascular and IR Procedures: A Society of Interventional Radiology Practice Parameter Update Endorsed by the Cardiovascular and Interventional Radological Society of Europe and the Canadian Association for

to oropharyngeal ?ora, which can potentially seed the skin entry site. This procedure carries a peristomal infection rate of approximately 30% (156). Prophylactic antibiotic therapy is therefore recommended for all patients undergoing this procedure with antimicrobial agents targeting skin and oropharyngeal bacteria, eg, cefazolin followed by oral/enteric cephalexin (156). (New data reviewed, recommendations updated.) Liver Tumor Ablation In 2015, Bhatia et al (157) described a very low incidence of hepatic ab (...) bacterial seeding, and a one-time dose of cefazolin covering skin?ora is reasonable. (New data reviewed, no changes to recommendations.) Other Tumor Ablation Thereremainsno consensusasto theuse ofantibioticprophylaxisforlung, adrenal, bone, or other solid-tumor ablation. Given that the thermal injury incurred during these procedures could create a hospitable environment for bacterialinfection,asingledoseofprophylacticantibioticagentstargetedto skin ?ora is recommended by some authors (165,166). For lung

2019 Society of Interventional Radiology

26. A systematic review into the methodologies used to document the impact of er: YAG laser on the skin and mucosa as well as its effects

A systematic review into the methodologies used to document the impact of er: YAG laser on the skin and mucosa as well as its effects Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne (...) and abstract, followed by full-text screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title-abstract screening: 1. Not an original full research paper (e.g. review, editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6

2018 PROSPERO

27. Skin Cosmetic Procedure

Procedure Aka: Skin Cosmetic Procedure , Aesthetic Procedure , Skin Plastic Surgery , Aesthetic Surgery II. Procedures: Office based Skin injections ( ) Laser Phorejuvenation Exfoliation Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Skin Cosmetic Procedure." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Esthetic Surgery (C0162472) Concepts (...) Skin Cosmetic Procedure Skin Cosmetic Procedure Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Skin Cosmetic Procedure Skin Cosmetic

2018 FP Notebook

28. Comparison of efficacy and safety of a novel 755-nm diode laser with conventional 755-nm alexandrite laser in reduction of axillary hairs. (Abstract)

in none of skin biophysical parameters. 755 nm diode laser is suitable for hair removal procedures and it is as effective and safe as the 755 nm alexandrite laser in skin types III-IV. (...) Comparison of efficacy and safety of a novel 755-nm diode laser with conventional 755-nm alexandrite laser in reduction of axillary hairs. The aim of this study was to compare the efficacy and safety of a novel diode system emitting 755 nm wavelength with conventional 755 nm alexandrite laser in skin types III and IV. It was a randomized, right-left comparison, assessor-blind, clinical study. Sixteen female volunteers age 29.52 ± 9.52 were randomly assigned to receive six treatment sessions

2019 Lasers in medical science Controlled trial quality: uncertain

29. Corneal Inlay Damage After Cosmetic Laser Treatment of the Eyelid With Long-Pulsed Nd:YAG Laser. (Abstract)

of the lamellar pocket of the inlay. He underwent explant of the inlay and debridement 48 hours later because of deteriorating VA and increasing corneal haze.Application of long-pulsed Nd:YAG laser at 1064 nm to the middle one-third of both upper eyelids and the periorbital region in a man with a corneal inlay implant. Corneal shields were not worn during the procedure. The peak penetration depth of this laser system is approximately 4 mm. The mean (SD) thickness of the upper eyelid in Asian eyes is 1.127 (...) Nd:YAG laser treatment to the periorbital skin and eyelids. Furthermore, these findings suggest that laser treatment to the eyelids should be avoided and that protective eyewear or corneal shields are recommended during cosmetic facial laser treatment in all patients.

2019 JAMA ophthalmology

30. The effect of repeated laser stimuli to ink-marked skin on skin temperature—recommendations for a safe experimental protocol in humans Full Text available with Trip Pro

The effect of repeated laser stimuli to ink-marked skin on skin temperature—recommendations for a safe experimental protocol in humans Background. Nd:YAP laser is widely used to investigate the nociceptive and pain systems, generating perpetual and laser-evoked neurophysiological responses. A major procedural concern for the use of Nd:YAP laser stimuli in experimental research is the risk of skin damage. The absorption of Nd:YAP laser stimuli is greater in darker skin, or in pale skin (...) over marked skin, but found nothing. Methods. We designed an experimental protocol to define safe parameters for the use of Nd:YAP laser stimuli over skin that has been marked with black dots, and used thermal imaging to assess the safety of the procedure at the forearm and the back. Results. Using thermal imaging and repeated laser stimulation to ink-marked skin, we demonstrated that skin temperature did not increase progressively across the course of the experiment, and that the small change

2016 PeerJ

31. Carbon dioxide (CO2) laser ablation versus other surgical treatment of condylomata acuminata

, including cryotherapy, laser therapy, and excisional procedures. The first line of defense against CA typically involves patient-administered topical treatment; however, the comparative effectiveness of such treatments has not been established, with some evidence suggesting that surgical techniques may be more effective in clearance rates than topical treatment. Description of Technology: This health technology assessment focuses on carbon dioxide (CO2) laser treatment compared with other surgical (...) ; can be used for clusters or multiple lesions on different areas of the skin; and that the laser ablates as it cuts, reducing blood loss. Patient Population: CO2 laser treatment can be used for all patients (including children and pregnant women). However, the studies analyzed for this health technology assessment were limited to adult populations. Clinical Alternatives: Alternative surgical treatments to CO2 laser for CA include electrocautery, cryotherapy, and surgical excision. Noninvasive

2017 Health Technology Assessment (HTA) Database.

32. Policy on the Use of Lasers for Pediatric Dental Patients

Policy on the Use of Lasers for Pediatric Dental Patients AMERICAN ACADEMY OF PEDIATRIC DENTISTRY ORAL HEALTH POLICIES 95 Purpose The American Academy of Pediatric Dentistry (AAPD) recognizes the judicious use of lasers as a beneficial instrument in providing dental restorative and soft tissue procedures for infants, children, and adolescents, including those with spe- cial health care needs. This policy is intended to inform and educate dental professionals on the fundamentals, types (...) and/or abstract and relevance to pediatric dental care. Expert and/or consensus opinion by experienced researchers and clinicians also was considered. Background Medicine began integrating lasers in the mid 1970s for soft tissue procedures. Oral and maxillofacial surgeons incorpo- rated the carbon dioxide (CO 2 ) laser into practice for removal of oral lesions in the 1980s. 1,2 The first laser specifically for dental use was a neodymium-yttrium-aluminum-garnet (Nd:YAG) laser, developed in 1987 and approved

2017 American Academy of Pediatric Dentistry

33. Laser lipolysis: skin tightening in lipoplasty using a diode laser. (Abstract)

who underwent laser lipolysis to correct contour deformities. Laser lipolysis was performed with a diode laser operating at two wavelengths (924 and 975 nm) controlled independently, and using three different tip lengths, allowing treatment of small, medium, and large areas of adipose tissue. The procedure was performed under local anesthesia in a surgical setting. To calculate the optimal cumulative energy, a total energy dose of 5 kJ/10 × 10-cm skin area was used as a safety parameter to prevent (...) Laser lipolysis: skin tightening in lipoplasty using a diode laser. New devices have been developed for surgical repair of deformities caused by localized fat deposits associated with skin laxity. The use of these devices requires the adoption of safety parameters. The aim of this study was to investigate skin tightening by laser lipolysis, using a dual-wavelength diode laser.This prospective, cross-sectional study was conducted between June of 2008 and July of 2010 with 41 consecutive patients

2015 Plastic and reconstructive surgery

34. Endoscopic Epidural Laser Decompression Versus Transforaminal Epiduroscopic Laser Annuloplasty for Lumbar Disc Herniation: A Prospective, Randomized Trial. (Abstract)

Endoscopic Epidural Laser Decompression Versus Transforaminal Epiduroscopic Laser Annuloplasty for Lumbar Disc Herniation: A Prospective, Randomized Trial. Lumbar radicular pain often results from lumbar disc herniation, spinal stenosis, or degenerative spondylolisthesis. Minimally invasive disc decompression procedures, such as nucleo-annuloplasty or epiduroscopic neural decompression by laser, have been devised to treat such pain.The short-term outcomes of disc decompression by endoscopic (...) epidural laser decompression (EELD) or transforaminal epiduroscopic laser annuloplasty (TELA) were compared in patients with lumbar radicular pain due to disc herniation.A randomized, prospective trial.The Department of Anesthesiology and Pain Medicine at Spine Health Wooridul Hospital in Daegu, Korea.A total of 97 patients were enrolled in this study; 48 patients underwent EELD and 49 underwent TELA. The pain relief was evaluated at baseline and at 1, 3, and 6 months post-procedure via the numeric

2018 Pain physician Controlled trial quality: uncertain

35. Treatment of burn scars in Fitzpatrick phototype III patients with a combination of pulsed dye laser and non-ablative fractional resurfacing 1550 nm erbium:glass/1927 nm thulium laser devices Full Text available with Trip Pro

erbium:glass stimulates collagen remodelling and the 1927 nm thulium targets epidermal processes, particularly hyperpigmentation. This combination addresses scar thickness, texture and colour with a low side effect profile and is particularly advantageous in patients at higher risk of post-procedure hyperpigmentation.Our cases suggest the combination of 595nm PDL plus NAFL 1550 nm erbium:glass/1927 nm thulium device is effective and well-tolerated for burn scar treatment in skin of colour. (...) Treatment of burn scars in Fitzpatrick phototype III patients with a combination of pulsed dye laser and non-ablative fractional resurfacing 1550 nm erbium:glass/1927 nm thulium laser devices Burn scars cause cosmetic disfigurement and psychosocial distress. We present two Fitzpatrick phototype (FP) III patients with burn scars successfully treated with combination pulsed dye laser (PDL) and non-ablative fractional lasers (NAFL).A 30-year-old, FP III woman with a history of a second-degree burn

2018 Scars, Burns & Healing

36. Laser Treatments in Early Wound Healing Improve Scar Appearance: -A Randomized Split-Wound Trial with Non-ablative Fractional Laser Exposures versus Untreated Controls. Full Text available with Trip Pro

Laser Treatments in Early Wound Healing Improve Scar Appearance: -A Randomized Split-Wound Trial with Non-ablative Fractional Laser Exposures versus Untreated Controls. In recent years, various lasers have increasingly been applied during wound healing to minimize scar formation. However, no consensus regarding treatment procedures exists.To assess scar formation clinically after three nonablative fractional laser (NAFL) exposures, targeting the inflammation, proliferation and remodelling wound (...) healing phases in patients vs. untreated controls.A randomized controlled trial was performed using a split-wound design to assess excisional wound halves treated with 1540-nm NAFL vs. no laser treatment. Three NAFL exposures were provided: immediately before surgery, at suture removal and 6 weeks after surgery. NAFL exposures were applied using two handpieces, sequentially distributing energy deeply and more superficially in the skin (40-50 mJ per microbeam). Evaluated at 3 months of follow-up

2018 British Journal of Dermatology Controlled trial quality: predicted high

37. Brimonidine gel (Mirvaso): risk of systemic cardiovascular effects; not to be applied to damaged skin

. It is important to avoid application to irritated or damaged skin, including after laser therapy. Published 21 June 2017 From: Therapeutic area: , Advice for healthcare professionals: cases of bradycardia, hypotension (including orthostatic hypotension), and dizziness after application of brimonidine gel have been reported, some of which required hospitalisation some cases were associated with application of brimonidine gel after laser procedures to the skin, which possibly caused increased absorption (...) of the gel warn patients not to apply brimonidine gel to irritated or damaged skin, including after laser therapy to the skin Brimonidine (Mirvaso) is a topical gel indicated for the symptomatic treatment of facial erythema of rosacea in adults. It is an α-2 adrenergic agonist. A routine European review identified post-marketing reports, including a small number of Yellow Cards, consistent with systemic (central) α-2 adrenergic effects, including bradycardia, hypotension (including orthostatic

2017 MHRA Drug Safety Update

38. Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin

Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin Comparative Effectiveness Review Number 199 Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin Evidence Summary Introduction Skin cancers, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common malignancies in the United States. 1 BCC and SCC, the 2 most common skin cancers, are collectively referred to as keratinocyte carcinomas. Over 5.4 million of these lesions are diagnosed (...) in 3.3 million people in the United States annually, 2, 3 and the global burden of disease from keratinocyte carcinomas is estimated at 12.9 disability- adjusted life years per 100,000 persons. 4 Generally keratinocyte carcinomas are not aggressive and do not metastasize or kill as often as melanoma, which is the third most common skin cancer. 5 However, SCC can metastasize and is estimated to kill between 3900 and 8800 people in the United States each year. 6 A more common problem is that BCC

2017 Effective Health Care Program (AHRQ)

39. Relationship of Skin Related SNP to Topical Skin Care Product

Retin-A®, Retin-A Micro®, Renova®, Avita®, Tazorac®, or Differin® within 2 weeks prior to the start of the study. Use of oral retinoids within 6 months of the study start. Subjects must not have had mid-depth or superficial chemical peel or other anti-aging procedures on the face (laser, intense pulsed light, injectable fillers microdermabrasion, etc.) within 2 months of the study start. Known allergies or sensitivities to test material ingredients or any topical skin care product (i.e., alpha (...) Relationship of Skin Related SNP to Topical Skin Care Product Relationship of Skin Related SNP to Topical Skin Care Product - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Relationship of Skin Related SNP

2018 Clinical Trials

40. Dynamic Optical Coherence Tomography(D-OCT) Aging Study: A Preliminary Evaluation of Structural Differences Between Young and Aged Skin, Cellulite and Atrophic Acne Scars in Female Caucasian Subjects With Fitzpatrick Skin Types I-III Utilizing Non-invasiv

. For standardization, this procedure will be performed with SkinMedica Facial Cleanser (to remove makeup and cleanse the face and thigh (if applicable)) for all the participants. Other Name: SkinMedica® Facial Cleanser Group B - Aged skin (55 - 75 years old) Assessments will be made after facial cleansing on areas being imaged utilizing VivoSight Dynamic Optical Coherence Tomography (D-OCT). Post-study D-OCT images will be processed with VivoSight software. Assessments of participant's overall photodamage (...) hepatitis, immune deficiency, or autoimmune. Individuals who have a pre-existing or dormant dermatologic condition (e.g. history of severe psoriasis, atopic dermatitis, rosacea, skin cancer, etc.) Individuals who have routinely used any of the following topical products, prescription products, or had any of the listed treatments/procedures within the listed time frame prior to study entry or will use during study: Any product that the investigator deems that could affect the study objectives

2018 Clinical Trials

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