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Laser Skin Procedure

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3361. Topical 5-ALA-PDT With Blu-U Therapy Versus Topical 5-ALA With Pulse Dye Laser In Treating Recalcitrant Acne Vulgaris

pressure on lesions.Skin will be exposed to DUSA Blu-U light (417nm). Experimental: 2 5-ALA Application and exposure using Candela V-beam Pulse Dye Laser to 1/2 of face. Drug: 5-ALA with Candela V-beam Pulse Dye Laser 20% 5-ALA Levulan Kerastick will be crushed and prepared for application after shaking for at least 3 minutes. Topical 5-ALA will be applied liberally on skin with extra pressure on lesions.Skin will be exposed to Candela V-beam Pulsed Dye Laser (595 nm). Outcome Measures Go to Primary (...) Topical 5-ALA-PDT With Blu-U Therapy Versus Topical 5-ALA With Pulse Dye Laser In Treating Recalcitrant Acne Vulgaris Topical 5-ALA-PDT With Blu-U Therapy Versus Topical 5-ALA With Pulse Dye Laser In Treating Recalcitrant Acne Vulgaris - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2008 Clinical Trials

3362. Efficacy Study of GLYC-101 to Evaluate Outcomes After Post-laser Ablation

volunteer subjects undergoing retro-auricular Carbon Dioxide Laser Skin Resurfacing (CO2 LSR). The study will observe the effects of the topical agent over the course of 1 month following the treatment. as a preparation for study GLYC-101-1b (Double-blind, randomized, placebo-controlled Phase 2 Pilot Study to investigate the safety and efficacy of 1.0 % topically applied GLYC 101 compared to placebo, in patients undergoing Carbon Dioxide Laser Skin Resurfacing). Study Design Go to Layout table for study (...) Dioxide Laser Skin Resurfacing. Study Start Date : March 2008 Actual Primary Completion Date : April 2008 Actual Study Completion Date : August 2008 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: 1 GLYC-101 Active Retro-auricular Site (1 per participant) Drug: GLYC-101 gel (1.0 %) Administration on Day 1, 3 and 5 post laser ablation. Placebo Comparator: 2 Comparator Placebo Retro-auricular Site (1 per

2008 Clinical Trials

3363. NdYag Laser for Acne Keloidalis Nuchae

Party): Iltefat Hamzavi, Henry Ford Health System Study Details Study Description Go to Brief Summary: Acne Keloidalis Nuchae (AKN) is a long standing hair follicle disease with bumps and scars on the skin of the back of the head and neck. The purpose of this new study is to determine how well a hair removal laser (NdYag Laser) works in treating AKN. Condition or disease Intervention/treatment Phase Acne Keloidalis Nuchae NdYag Laser AKN Acne Keloidalis AK Dermatitis Papillaris Capillitii (...) NdYag Laser for Acne Keloidalis Nuchae NdYag Laser for Acne Keloidalis Nuchae - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. NdYag Laser for Acne Keloidalis Nuchae The safety and scientific validity

2008 Clinical Trials

3364. Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation

by: Glycotex, Inc. Study Details Study Description Go to Brief Summary: The primary objectives of this study are to evaluate safety and efficacy of topically applied Glucoprime gel (GLYC-101, 0.1% and GLYC-101, 1.0%) in promoting wound healing in cosmetic surgery patients undergoing Carbon Dioxide Laser Skin Resurfacing (CO2 LSR) of the lower eyelids. The study will observe the effects of the topical agent over the course of 1 month following the initial treatment. Condition or disease Intervention (...) the Safety and Efficacy of 0.1% and 1.0% Topically Applied GLYC-101, Compared to Placebo, in Patients Undergoing Carbon Dioxide Laser Skin Resurfacing of the Lower Eyelids. Study Start Date : October 2008 Actual Primary Completion Date : January 2010 Actual Study Completion Date : January 2010 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: 1 GLYC-101 Gel, 0.1% on one eyelid and Placebo Gel on the other

2008 Clinical Trials

3365. Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator Veins

and the satisfaction of the patient. Patient symptom assessment - CEAP Class, best=0 (no visible or palpable signs of venous disease) & worst=6 (Skin changes in conjunction with active ulceration), VDS, best=0 (asymptomatic) & worst=3 (unable to carry out usual activities even with compression and/or limb elevation) and VCSS, best=0 (absent) & worst=3 (severe). Patient satisfaction - modified Odom's criteria, best=excellent (I am very satisfied with the results of my laser treatment) & worst=poor (I am (...) Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator Veins Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator Veins - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2007 Clinical Trials

3366. Combined Alexandrite and Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks

of California, Irvine Collaborator: Beckman Laser Institute University of California Irvine Information provided by (Responsible Party): Beckman Laser Institute and Medical Center, University of California, Irvine Study Details Study Description Go to Brief Summary: Port wine stain is a congenital, progressive vascular malformation of skin involving post-capillary venules that occurs in an estimated 4 children per 1,000 live births. Approximately 1,200,000 individuals in the United States and twenty-six (...) macules, but lesions tend to darken progressively to purple, and by middle age, often become raised as a result of the development of vascular nodules. Hypertrophy of underlying soft tissue further disfigures the facial features of many patients. Condition or disease Intervention/treatment Phase Port Wine Stain Procedure: laser treatment of port wine stain birthmarks Phase 1 Detailed Description: The researcher can use alexandrite and pulsed dye lasers pulses combined delivery to improve port wine

2007 Clinical Trials

3367. Combined Photodynamic and Pulsed Dye Laser Treatment of Port Wine Stains

laser (PDL) therapy (PDT + PDL). The standard treatment for PWS is PDL alone. This lightens some PWS but many lesions are not completely removed. PDT uses a medication and light together to cause injury to a target. The medication is given and then light is directed at the desired area of treatment to achieve an effect. PDT has been used to treat some skin conditions including pre-cancers and skin cancers. Using PDT or PDT immediately followed by PDL therapy may improve PWS lightening. At this time (...) , both PDT and PDT + PDL therapy for treatment of PWS is investigational. The type and amount of medication and light which may be used to treat PWS is not known, and is likely to be different than those used for other PDT treatments. Condition or disease Intervention/treatment Phase Port Wine Stains Drug: Combined Photodynamic & Pulsed Dye Laser Treatment Not Applicable Detailed Description: Procedures will be performed at the Surgery Laser Clinic at the Beckman Laser Institute at the University

2007 Clinical Trials

3368. American Breast Laser Ablation Therapy Evaluation

. fibroadenomas, papillomas, etc). Data captured will assess the potential advantages and disadvantages of the procedure as compared with lumpectomy. Tumor characteristics, equipment used, complications, patient satisfaction and cosmesis ratings will also be tracked. Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 200 participants Observational Model: Case-Only Time Perspective: Prospective Official Title: American Breast Laser Ablation Therapy (...) American Breast Laser Ablation Therapy Evaluation American Breast Laser Ablation Therapy Evaluation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. American Breast Laser Ablation Therapy Evaluation (ABLATE

2008 Clinical Trials

3369. Correlation of MR Thermal Imaging to Actual Size of Ablation During Laser Ablation Therapy

Cancer Center Collaborator: BioTex, Inc. Information provided by (Responsible Party): M.D. Anderson Cancer Center Study Details Study Description Go to Brief Summary: The goal of this clinical research study is to learn how well magnetic resonance thermal imaging (MRTI) can check the amount of tumor being destroyed using a therapy called laser ablation (a procedure that uses lasers to create heat that is designed to destroy cancer cells). Condition or disease Intervention/treatment Phase Advanced (...) Cancer Bone Metastases Procedure: Laser Ablation Procedure: Magnetic Resonance Thermal Imaging Phase 4 Detailed Description: Laser ablation is designed to destroy tumor tissue with the use of fiber optics that are placed directly into the tumor to deliver laser light energy into the tissue. In this study, tumor destruction will be checked using MRTI. MRTI is very similar to other MRI techniques, but instead of providing imaging data, MRTI will provide temperature data for cancerous areas in the body

2008 Clinical Trials

3370. Treatment of Surgical Scars With Fractional Photothemolysis Versus Pulse Dye Laser

of the erythematous and telangiectasia component of surgical scars. Comparison of the outcome of the half of the surgical scar treated with Fraxel SR laser versus the outcome of the contralateral half of the surgical scar which will be treated with the V-Beam Pulse Dye Laser. Condition or disease Intervention/treatment Phase Post Surgical Scars Procedure: Laser treatment Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 12 (...) Comparator: Fraxel Fraxel laser treatment Procedure: Laser treatment Fraxel and pulsed dye laser Other Names: -Fraxel SR Laser (Reliant Technologies, Inc.) -V-Beam Pulse Dye laser (Candela Corporation) Active Comparator: PDL Pulsed dye laser treatment Procedure: Laser treatment Fraxel and pulsed dye laser Other Names: -Fraxel SR Laser (Reliant Technologies, Inc.) -V-Beam Pulse Dye laser (Candela Corporation) Outcome Measures Go to Primary Outcome Measures : Overall cosmetic appearance, relative

2008 Clinical Trials

3371. Safety and Efficacy of Different Intervals of Pulsed Dye Laser Sessions on Improvement of Surgical Scars

on improvement of surgical scars. Condition or disease Intervention/treatment Phase Scar Procedure: pulsed dye laser therapy Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 0 participants Allocation: Randomized Intervention Model: Factorial Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Prevention Official Title: The Effect of Different Intervals of 595-nm Pulsed Dye Laser (...) Sessions on Improvement of Surgical Scars: A Double Blind Randomised Clinical Trial Study Start Date : July 2007 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: A pulsed dye laser and dynamic cooling device at 3 weeks intervals Procedure: pulsed dye laser therapy Treatment will begin on the day of suture removal. Each scar will be divided into 3 equal parts. One part will be randomly allocated

2007 Clinical Trials

3372. Safety and Efficacy of Different Onset Times of Treatment With Pulsed Dye Laser on Improvement of Surgical Scars

laser on improvement of surgical scars. Condition or disease Intervention/treatment Phase Scar Procedure: pulsed dye laser therapy Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 15 participants Allocation: Randomized Intervention Model: Factorial Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Prevention Official Title: The Effect of Different Onset Times of Treatment (...) With 595-nm Pulsed Dye Laser on Improvement of Surgical Scars: A Double Blind Randomised Clinical Trial Study Start Date : January 2008 Actual Primary Completion Date : December 2008 Actual Study Completion Date : January 2009 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: A pulsed dye laser and dynamic cooling device on the day of suture removal Procedure: pulsed dye laser therapy Each scar

2007 Clinical Trials

3373. Multiphoton Laser Scanning Microscopy in Cutaneous Optical Pathology

Intervention/treatment Optical Biopsy Cutaneous Pathology Dermatopathology Behavioral: Multiphoton laser image in cutaneous pathology Detailed Description: For skin diseases, the most convincing method for diagnosis to date is surgical biopsy. However, a skin biopsy is an invasive procedure which carries the risk of tissue damage, wound infection and scar formation. To solve the inconvenience from surgical biopsy, multiphoton laser scanning microscopy is a developing, non-invasive method for observing (...) the cutaneous anatomy and pathology. Multiphoton laser scanning microscopy is good in tissue penetration and resolution with less tissue damage. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy. A good correlation in multiphoton image may serve as optical biopsy for cutaneous pathology and spare the invasive procedure of skin biopsy. Study Design Go to Layout table for study information Study Type : Observational

2007 Clinical Trials

3374. Study of Light Treatment and Laser Treatment for Melasma

Description Go to Brief Summary: The purpose of this study is to determine the efficacy of light treatment and laser treatment for melasma. These treatment options have not been thoroughly explored in the treatment of melasma. By studying the effect of different treatments, a better treatment plan may be developed for people with melasma. Condition or disease Intervention/treatment Phase Melasma Procedure: Light Treatment Procedure: Laser Treatment Not Applicable Detailed Description: The objective (...) : Single (Outcomes Assessor) Primary Purpose: Treatment Official Title: A Randomized, Rater-blinded, Split-face Comparison of the Efficacy of Intense Pulse Light vs. Q-switched Nd:Yag Laser for the Treatment of Melasma. Study Start Date : April 2007 Actual Primary Completion Date : September 2009 Actual Study Completion Date : September 2009 Arms and Interventions Go to Arm Intervention/treatment Experimental: 1 Light therapy Procedure: Light Treatment Light treatment applied to half of the face

2007 Clinical Trials

3375. Acupuncture and Laser Acupoint Treatment on Hypertension

provided by: Logan College of Chiropractic Study Details Study Description Go to Brief Summary: To determine the effect of acupuncture and laser acupuncture point treatment on hypertensive subjects. Condition or disease Intervention/treatment Phase Hypertension Device: Laser acupoint treatment Procedure: Acupuncture Phase 1 Detailed Description: The specific aims of the study are to test the effectiveness of acupuncture and laser acupoint on hypertension. The hypothesis is: the stimulation of a pattern (...) on Hypertension Study Start Date : February 2008 Estimated Primary Completion Date : January 2009 Estimated Study Completion Date : June 2009 Resource links provided by the National Library of Medicine related topics: related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Acupuncture Procedure: Acupuncture Needle acupuncture on ST36 and LI11. Experimental: Laser Acupoint Device: Laser acupoint treatment Laser Other Name: Laser Outcome Measures Go to Primary Outcome Measures

2007 Clinical Trials

3376. Treatment of Cutaneous Lupus Erythematosus (CLE) With the 595 nm Flashlamp Pulsed Dye Laser

of Pennsylvania Information provided by: University of Pennsylvania Study Details Study Description Go to Brief Summary: The purpose of using the 595 nm Vbeam Perfecta™ flashlamp-excited, pulsed dye laser in this study is to help improve study patients' skin disease. Cutaneous lupus erythematosus (CLE) often presents with disfiguring vascular lesions which are frequently difficult to treat with the available therapeutic measures, such as photoprotection, topical steroids, and antimalarials. Laser therapy (...) provides an alternative treatment option for CLE patients. Although there has been documented experience with laser treatment in CLE patients, no study comparing treated lesions to the natural course of the disease has been conducted. Condition or disease Intervention/treatment Phase Cutaneous Lupus Erythematosus Procedure: laser treatment (Candela Vbeam Perfecta™) Phase 2 Detailed Description: The Candela Vbeam PerfectaTM is an FDA approved 595nm Flashlamp Pulsed Dye Laser (PDL) that is being used

2007 Clinical Trials

3377. Enhanced Safety Aesthetic Laser System

vascular lesions or/and Facial rhytides Exclusion Criteria: Age below 18 or above 75 year old. Use of photosensitive medications Photosensitive diseases Active infection of any type and active infection or or a history of Herpes Simplex in the treated site Exposure to sun or artificial tanning during the last 3–4 weeks For treatment of facial rhytides- surgical or nonsurgical facial procedure (i.e., laser skin resurfacing, dermabrasion, phenol peel, nonablative laser, or temporary/permanent filler (e.g (...) : The purpose of this study is to determine whether a new laser system provides better safety and efficacy than existing lasers in popular cosmetic procedures such as hair removal, treatment of cosmetically disturbing vascular lesions and rhytides. Condition or disease Intervention/treatment Phase Hirsutism Hypertrichosis Telangiectases Rhytides Device: Peterio Not Applicable Detailed Description: Cosmetic lasers are a well-established, popular modality for removal of unwanted hair, treatment of all types

2007 Clinical Trials

3378. Study on the Effect of NdYag Laser for the Treatment of Hidradenitis Suppurativa

. Evaluate the histopathologic changes of YAG therapy on affected skin Second phase of study: Prospective, controlled clinical and histologic study of patients with Hurley Stage II HS disease. 19 patients of skin types II to VI with Hurley Stage II hidradenitis suppurativa lesions of the axilla and groin. This is a different set of patients than those treated in the first phase of the study above. This study primarily focuses on and further characterizes the histologic changes after laser treatment (...) . Condition or disease Intervention/treatment Phase Hidradenitis Suppurativa Procedure: Long-pulsed Nd:YAG laser 1064 nm Not Applicable Detailed Description: Background: Hidradenitis suppurativa (HS) is a chronic suppurative recurrent disease of the apocrine glands. Histological studies suggest that it is a disease of the follicles with apocrine involvement as a secondary event. There is limited efficacy of medical treatments and high morbidity for surgical treatment. Limited data are available

2007 Clinical Trials

3379. Study of Acid Peel and Laser for the Treatment of Melasma

Details Study Description Go to Brief Summary: The objective of this study is to evaluate laser treatment and acid peel for the treatment of melasma. Condition or disease Intervention/treatment Phase Melasma Procedure: Laser Treatment Procedure: Acid Peel Not Applicable Detailed Description: The purpose of this study is to evaluate the safety and efficacy of laser treatment and acid peel for the treatment of melasma. Study Design Go to Layout table for study information Study Type : Interventional (...) Intervention/treatment Experimental: 1 Laser Treatment Procedure: Laser Treatment Laser treatment to half of the face at each study visit Experimental: 2 Acid peel Procedure: Acid Peel Acid peel to half of the face at each study visit Outcome Measures Go to Primary Outcome Measures : MASI [ Time Frame: 20 weeks ] Secondary Outcome Measures : Safety [ Time Frame: 20 weeks ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important

2007 Clinical Trials

3380. Study of the Effects of the Pulsed-dye Laser at 585nm and 595nm to Treat Post-operative Scars on Suture-removal Day

, 2007 Last Update Posted : June 28, 2016 Sponsor: University of Miami Information provided by (Responsible Party): Keyvan Nouri, University of Miami Study Details Study Description Go to Brief Summary: The purpose of this study is to compare the effects of the pulsed-dye laser (PDL) at two different wavelengths, 585nm and 595nm, in the treatment of post-surgical scars starting on suture-removal day. Condition or disease Intervention/treatment Phase Cicatrix Scars Procedure: PDL 450 microseconds (...) Procedure: PDL 1.5 milliseconds Not Applicable Detailed Description: Many treatment modalities have been used for the treatment of scars such as dermabrasion, cryotherapy, intralesional corticosteroids, surgical scar revision, and lasers, among others. Previous studies have shown that treatment of scars with the pulsed dye laser (PDL) alone or in combination with other modalities (e.g. corticosteroids, 5-Fluoruracil, silicone sheets) improves the vascularity, pliability, color, and height

2007 Clinical Trials

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