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Laser Skin Procedure

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181. Evaluation of the Efficacy and Safety of PiQo4 for Facial Skin Rejuvenation

. Condition or disease Intervention/treatment Phase Skin Rejuvenation Device: PiQo4 laser system Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 20 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Evaluation of the Efficacy and Safety of PiQo4 for Facial Skin Rejuvenation Actual Study Start Date : March 12, 2018 Estimated Primary Completion (...) Date : July 30, 2019 Estimated Study Completion Date : August 30, 2019 Arms and Interventions Go to Arm Intervention/treatment Experimental: Facial skin rejuvenation Facial skin rejuvenation using PiQo4 laser system Device: PiQo4 laser system The PiQo4 laser system Outcome Measures Go to Primary Outcome Measures : Fitzpatrick Elastosis Score (FES) scale [ Time Frame: Baseline, 1 month follow up ] Fine lines/wrinkles and elastosis improvement will be classified by the Fitzpatrick-Goldman Elastosis

2017 Clinical Trials

182. Cosmetic Study of AO+Mist in Improving the Appearance of Skin Afflicted With Keratosis Pilaris

is in good general health Diagnosis of keratosis pilaris involving areas of the body affected bilaterally Subject has Fitzpatrick Skin Type I-VI Willing to refrain from using any treatments, other than the investigational product, including antibiotics, for acne present on the face. Ability to comprehend and comply with procedures Agree to commit to participate in the current protocol Provide written informed consent prior to any study procedure being performed (all subjects should be able to understand (...) the informed consent form and any other documents that subjects are required to read) Exclusion Criteria: Male and female subjects under 18 years or over 65 years of age Female subjects who are pregnant or lactating Subjects who have received laser therapy to the KP affected area in the past 1 year Subjects with a concurrent diagnosis of another skin condition or malignancy Subjects with tan or sunburn over the area affected by KPin the past month Subjects with open, non-healing sores or infections at any

2017 Clinical Trials

183. Infrared and Broadband Light for Skin Aging

moderate on the extensor forearms Exclusion Criteria: 1. Unable to understand and sign informed consent form 2. Unable to comply with study procedures 3. Pregnant or lactating 4. Prior treatment to forearms including topical retinoid, laser treatment, photodynamic treatment, prescription topical agents x 1 month 5. Active skin conditions that precluding treatment including zoster, blistering skin disease, psoriasis, atopic dermatitis, abnormal scarring, skin cancer in the area of study treatment 6 (...) Infrared and Broadband Light for Skin Aging Infrared and Broadband Light for Skin Aging - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Infrared and Broadband Light for Skin Aging The safety and scientific

2017 Clinical Trials

184. Virus-Induced Cancers of the Skin and Mucosa: Are We Dealing with “Smoking Guns” or “Smoke and Mirrors” in the Operating Theatre? (PubMed)

Virus-Induced Cancers of the Skin and Mucosa: Are We Dealing with “Smoking Guns” or “Smoke and Mirrors” in the Operating Theatre? Human papillomavirus (HPV) alone is thought to cause ~610,000 cases of cancer per year, and is the dominant aetiological agent for ano-genital (esp. cervical) and head and neck cancers (esp. oropharyngeal). Merkel cell polyomavirus (MCV) is a more recently discovered virus which causes Merkel cell carcinoma, a rare but highly aggressive skin malignancy.We (...) explored the available published evidence to see if transmission of live HPV or MCV virus in smoke generated by laser or diathermy was feasible, and would pose an infection risk. Long-term infection with such carcinogenic viruses would then pose an increased risk for the development of virus-induced cancers in medical personnel.The morphological structures of both HPV and MCV are very similar, and the size, external capsids and genomic structures show striking similarity. Both viruses have a non

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2017 Dermatology and therapy

185. Oily Skin: A review of Treatment Options (PubMed)

Oily Skin: A review of Treatment Options One of the most common dermatologic concerns is oily skin, and the demand for effective treatment options is ever apparent. This review article addresses numerous topical treatment options such as retinoids, olumacostat glasaretil, and various cosmeceutical agents. several systemic and procedural techniques that incorporate isotretinoin, spironolactone, oral contraceptives, botulinum toxin, photodynamic therapy, and lasers are reviewed as well. Each

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2017 The Journal of clinical and aesthetic dermatology

186. Laser thermal therapy monitoring using complex differential variance in optical coherence tomography (PubMed)

is marked by the transition from high CDV upon heating to a significantly reduced CDV once the tissue is coagulated, in 3 different tissue types ex vivo: skin, retina, and esophagus. The ability to delineate thermal lesions in multiple tissue types at high resolution opens up the possibility of performing microscopic image-guided procedures in a vast array of epithelial applications ranging from dermatology, ophthalmology, to gastroenterology and beyond.© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. (...) Laser thermal therapy monitoring using complex differential variance in optical coherence tomography Conventional thermal therapy monitoring techniques based on temperature are often invasive, limited by point sampling, and are indirect measures of tissue injury, while techniques such as magnetic resonance and ultrasound thermometry are limited by their spatial resolution.  The visualization of the thermal coagulation zone at high spatial resolution is particularly critical to the precise

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2016 Journal of biophotonics

187. Photoaging and the clinical utility of fractional laser (PubMed)

of the fractionated radiation for the treatment of photoaging, by Mainstein, represented a great event. The stimulation of collagen occurred through fractional laser beams, which would reach the selected area while saving islands of sound skin. These islands accelerated the process of cicatrization of the treated tissue and shortened the postprocedure time. Furthermore, the fractionated radiation presented a smaller range of side effects, increasing the safety of the procedure. As mentioned earlier, as fractional (...) lasers incise on the skin, they leave islands of healthy skin that accelerate recovery, while generating necrosis columns. Such necrosis columns remove damaged extracellular matrix material, allowing resettlement of fibroblasts. Such resettled fibroblasts, under the influence of a new tensile strength, restart to produce structures for extracellular matrix, such as collagen, elastin, and proteoglycans, in a more physiological way. Fractional lasers are considered by many dermatologists as the best

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2016 Clinical, cosmetic and investigational dermatology

188. Laser Acupuncture for Postpartum Weight Retention

' body weight, body mass index, and waist circumference will be analyzed with ANOVA between laser acupuncture and control group. Condition or disease Intervention/treatment Phase Postpartum Weight Retention Procedure: laser acupuncture Procedure: sham laser acupuncture Phase 3 Detailed Description: Objective: Gestational weight gain and weight retention at 1 year after delivery are associated with long-term obesity. The investigators aimed to investigate the effect of laser acupuncture therapy (LAT (...) Official Title: Laser Acupuncture Therapy in Patients With Postpartum Weight Retention: A Randomized Controlled Trial Study Start Date : January 2014 Actual Primary Completion Date : December 2015 Actual Study Completion Date : December 2015 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: verum laser acupuncture verum laser acupuncture Procedure: laser acupuncture Subjects were treated at acupoints

2016 Clinical Trials

189. Fusion Guided Focal Laser Ablation of Prostate Cancer

of Health Clinical Center (CC) Study Details Study Description Go to Brief Summary: Background: Prostate cancer is the most common non-skin cancer in U.S. men. Treatments for early or less aggressive disease are limited. Researchers want to test a device that destroys cancerous tissue with laser energy. They want to see if using it with ultrasound is more comfortable than using it with magnetic resonance imaging (MRI). Objectives: To test a cooled laser applicator system to treat prostate cancer lesions (...) Fusion Guided Focal Laser Ablation of Prostate Cancer Fusion Guided Focal Laser Ablation of Prostate Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Fusion Guided Focal Laser Ablation of Prostate

2016 Clinical Trials

190. A Study of a Novel Multi-Wavelength Laser for Tattoo Removal

A Study of a Novel Multi-Wavelength Laser for Tattoo Removal A Study of a Novel Multi-Wavelength Laser for Tattoo Removal - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study of a Novel Multi-Wavelength (...) Laser for Tattoo Removal The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02910505 Recruitment Status : Unknown Verified September 2016 by Cutera Inc.. Recruitment status was: Recruiting First Posted : September 22, 2016 Last Update Posted : January 23, 2018 Sponsor: Cutera Inc. Information provided

2016 Clinical Trials

191. Comparison of Laser Assisted Epidermal to Intradermal Administration of Seasonal Influenza Vaccine

vaccine Device: fractional Er:Yag laser Phase 1 Detailed Description: The skin is an attractive tissue for vaccination due to the impact of the cutaneous micro-environment on the adaptive and non-adaptive immune responses. Conventionally many vaccines are administered subcutaneously. Immune-competent cells however are not resident in the subcutaneous fat tissue, but instead are located in the epidermis and the dermis of the skin. Depending on the targeted skin layer and administration method (...) influenza vaccine influenza vaccine containing 15 µg haemagglutinin of three seasonal influenza virus strains recommended by WHO Other Name: INTANZA Device: fractional Er:Yag laser Fraction laser device to apply micorpores of defined depth and density into skin. Other Name: Pantec P.L.E.A.S.E. Active Comparator: Intradermal application 0,1 ml of Intanza (15 µg, seasonal trivalent influenza vaccine) will be intradermally injected in the deltoid area. Biological: seasonal influenza vaccine influenza

2016 Clinical Trials

192. Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas

physician. Concurrent chemoradiation will begin within 7 days of the LITT procedure. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 45 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Expedited Laser Interstitial Thermal Therapy and Chemoradiation for Patients With Newly Diagnosed High Grade Gliomas Actual Study Start Date : May 18, 2017 Estimated (...) Temozolomide Procedure: LITT MRI-guided laser interstitial thermal therapy uses a gas cooled side-firing (directional) laser and a variety of procedure specific tools to thermally ablate target tissue in-situ. Other Name: Laser interstitial thermal therapy Radiation: Radiation therapy One treatment of 2 Gy will be given daily 5 days per week for a total of 60 Gy over 6 weeks. All portals shall be treated during each treatment session. Doses are specified such that at least 95% of the planning target volume

2016 Clinical Trials

193. Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids

: Intralesional Triamcinolone Acetonide Not Applicable Detailed Description: Intralesional corticosteroids remain the gold standard treatment for keloids. However, more effective therapies are desperately desired. Ablative fractional laser (AFL) treatment facilitates delivery of intralesional steroid more deeply and uniformly into the skin by creating vertical channels. Recent studies have showed that fractional laser assisted steroid therapy can be effective in the treatment of keloids. However the studies (...) Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2016 Clinical Trials

194. Laser-assisted Topical Administration of Etanercept (Enbrel®) in Patients With Mild to Moderate Plaque-type Psoriasis

different plaques of the first 5 patients will be randomized and administered the respective treatments only once. Enrollment will be suspended after the 5th patient has been enrolled to permit the data monitoring committee (DMC) to review of the initial safety data from these first 5 patients to reassess risk. Based on this review, the DMC will make one of three recommendations: to continue the study as planned, to continue the study with adjustments to study procedures, such as changes to laser (...) with the P.L.E.A.S.E.® Professional laser, 0.0625 ml of Etanercept (50 mg/ml) solution for injection in pre-filled syringes will be applied to the microporated surface of the lesion. The treated area will then be covered with OpSiteTM Flexigrid Transparent Dressing for 4 hours. This treatment procedure will be repeated twice weekly for 8 weeks. Drug: Laser microporation + topical application of Etanercept Immediately following microporation of a 5 cm² area of the designated plaque with the P.L.E.A.S.E.®

2016 Clinical Trials

195. TR-987 vs. Placebo Following Fractionated CO2 Laser Resurfacing of the Chest

-ablative laser, light or radio frequency treatment and/or has had a Dermabrasion (deep skin peel) or ablative laser treatments on their chest must have discontinued the drug/treatment and/or have completed the treatment or the procedure at least 3 months prior to entering the study. A subject with a history of keloids or hypertrophic scars A subject that has previously been treated with a systemic retinoid within the past year (e.g., Accutane®, Roche Dermatologics) A female subject who is pregnant (...) without Silon Bandage Not Applicable Detailed Description: This is a double-blind, randomized, placebo-controlled, chest clinical study with a single study site. Forty subjects will receive fractionated CO2 laser resurfacing of the chest. . Immediately following the procedure (Day 0), postoperative gel randomized to the chest (TR-987 or placebo), will be applied with a thickness of 1-2 mm by a non-blinded coordinator, along with a split-chest Silon TSR bandage. Subjects will return for follow up

2016 Clinical Trials

196. Laser Therapy for Pediatric Burn Scars

by their symptomatic presentation (scars are typically raised, red, and stiff). The individuals who will be involved in the diagnosis will be experienced burn care providers and highly familiar with diagnosing hypertrophic burn scars. Exclusion Criteria: 11) Patients with concomitant skin disease (i.e. chronic skin conditions, herpes infection) 2) Patients with a history of keloid scarring 3) Patients who cannot tolerate the intravenous (IV) sedation used to perform laser therapy procedures § 4) Patients who have (...) , The Hospital for Sick Children Study Details Study Description Go to Brief Summary: A new era of outcomes for pediatric burn patients has begun as burn care continues to improve. Unfortunately, complete restoration of burn-injured skin may be limited by the development of hypertrophic scarring. Treatment with ablative fractional carbon dioxide laser therapy is one of the newest forms of scar therapy available. Although laser therapy has only been adopted by burn clinicians within the last several years

2016 Clinical Trials

197. Clinical Study of the CO2RE Laser Device Performance for Vaginal Atrophy Treatments

provided by (Responsible Party): Syneron Medical Study Details Study Description Go to Brief Summary: The CO2RE laser system is a fractional CO2 laser that is FDA approved under a 510(k) K101321 for dermatologic procedures requiring ablation and coagulation of soft tissues, including the skin Eligible subjects will undergo 3 treatments in 4±1 weeks interval on the Vagina (External/Vulva and Internal/Vagina) with the CO2RE device according to study protocol. Subject will return for to 5 follow-up (FU (...) and 1, 3, 6 and 12 months after last (third) treatment (± 2 weeks). Methodology described in protocol to evaluate efficacy of treatments will be carried out at each visit at the clinic. Device: CO2RE The CO2RE system device is intended for dermatological procedures requiring ablation, coagulation and resurfacing of soft tissue, including skin Outcome Measures Go to Primary Outcome Measures : Change from Baseline in Vulvovaginal Symptom Questionnaire [ Time Frame: Baseline, 1 , 2 , 3, 5, 8, and 14

2016 Clinical Trials

198. Split-tattoo Study Comparing the Safety and Efficacy of 670nm Picosecond Laser Versus 755 nm for Tattoo Removal

which might make it unsafe for the subject to participate in this study. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02912507 Locations Layout table for location information United States, Florida Laser Skin Solutions Jacksonville Jacksonville (...) Beach, Florida, United States, 32250 Sponsors and Collaborators Cutera Inc. Investigators Layout table for investigator information Principal Investigator: Jill Lezaic, DO Laser Skin Solutions Jacksonville More Information Go to Layout table for additonal information Responsible Party: Cutera Inc. ClinicalTrials.gov Identifier: Other Study ID Numbers: C-16-EN15 First Posted: September 23, 2016 Last Update Posted: September 25, 2017 Last Verified: September 2017 Individual Participant Data (IPD

2016 Clinical Trials

199. Multi-Wavelength Laser Tattoo Removal Pivotal Study

Multi-Wavelength Laser Tattoo Removal Pivotal Study Multi-Wavelength Laser Tattoo Removal Pivotal Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Multi-Wavelength Laser Tattoo Removal Pivotal Study (...) . Study Details Study Description Go to Brief Summary: Mult-center study to evaluate the safety and efficacy of an investigational version of the Cutera enlighten laser that offers multiple wavelengths for tattoo removal Condition or disease Intervention/treatment Phase Tattoo Removal Device: enLighten Laser Not Applicable Detailed Description: A multi-center prospective, open-label, uncontrolled pivotal study to evaluate the safety and efficacy of an investigational version of the Cutera enlighten

2016 Clinical Trials

200. 785nm Picosecond Laser for Treatment of Benign Pigmented Lesions

, e.g., lack of noticeable skin flaking, skin peeling and skin surface roughness History of immunosuppression/immune deficiency disorders (including HIV infection or AIDS) or currently using immunosuppressive medications Known allergy to lidocaine, tetracaine, Xylocaine or epinephrine Has had a laser procedure, a peel or has used lightening creams in the area to be treated with in the past six months Subjects with pigmented lesions that are considered not acceptable by the study doctor or any (...) 785nm Picosecond Laser for Treatment of Benign Pigmented Lesions 785nm Picosecond Laser for Treatment of Benign Pigmented Lesions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. 785nm Picosecond Laser

2016 Clinical Trials

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