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Laryngeal Neoplasm

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1. Comparative efficacy of six therapies for Hypopharyngeal and laryngeal neoplasms: a network meta-analysis. (PubMed)

Comparative efficacy of six therapies for Hypopharyngeal and laryngeal neoplasms: a network meta-analysis. Hypopharyngeal and laryngeal neoplasms are both fatal and hard to catch in early stages. Yet which treatment is the most efficacious one still remain unanswered. This network meta-analysis (NMA) was conducted to investigate effectiveness of six therapies being utilized in clinical practice nowadays.PubMed and Embase were retrieved to synthesize data. Direct and indirect evidence

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2019 BMC Cancer

2. Laryngeal Neoplasm

Laryngeal Neoplasm Laryngeal Neoplasm Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Laryngeal Neoplasm Laryngeal Neoplasm Aka (...) : Laryngeal Neoplasm , Laryngeal Tumor , Vocal Cord Cancer , Squamous Cell Carcinoma of the Larynx , Laryngeal Cancer , Laryngeal Squamous Cell Carcinoma From Related Chapters II. Epidemiology highest in middle age and over 60 years old (especially smokers) Men more commonly affected III. Pathophysiology (90% of malignant ) IV. Risk Factors abuse Elderly Chronic Disease V. Symptoms Chronic (longer than 2 weeks) (especially unilateral) Odynophagia VI. Signs: Laryngeal Exam Early Findings Small, white s

2018 FP Notebook

3. Transoral robotic surgery (TORS) for head and neck cancer of unknown primary, oropharyngeal cancer and supraglottic laryngeal cancer

learning curves and volume-outcome studies. The Medline, Medline in process, and Embase databases were searched. All results were limited to English language. Concepts used in all searches included: head and neck cancer/tumour/neoplasm/carcinoma, oropharyngeal cancer, supraglottic laryngeal cancer, transoral robotic surgery (TORS), da Vinci robotic assisted surgery. A full list of resources searched and terms used are available on request. Introduction The most common sites of cancers in the head (...) Transoral robotic surgery (TORS) for head and neck cancer of unknown primary, oropharyngeal cancer and supraglottic laryngeal cancer 74 1 Health technology description What is an evidence note? Evidence notes are rapid reviews of published secondary clinical and cost-effectiveness evidence on health technologies under consideration by decision makers within NHSScotland. They are intended to provide information quickly to support time-sensitive decisions. Information is available to the topic

2018 Evidence Notes from Healthcare Improvement Scotland

4. Laryngeal granuloma occurring after surgery for laryngeal cancer treated by surgical removal and immediate post-operative radiotherapy: A case report. (PubMed)

Laryngeal granuloma occurring after surgery for laryngeal cancer treated by surgical removal and immediate post-operative radiotherapy: A case report. Laryngeal granulomas are benign lesion that rarely occurs after surgery of laryngeal cancer. Until now there has not been standard treatment for it.The patient was diagnosed with laryngeal neoplasm one and half a month ago. Endoscopic low-temperature plasma knife in the radical excision of left vocal cord was performed under the general (...) anesthesia. Postoperative histopathological examination confirmed left vocal cord tumor was highly differentiated invasive squamous cell carcinoma (SCC). Then the patient suffered unexplained intermittent dyspnea which persisted nearly 1 month after the surgery. Laryngoscope examination showed granulation formation on the glottis.The patient was diagnosed with laryngeal granuloma 1 month after the surgery of laryngeal cancer.The patient received resection of the laryngeal mass, and pathological

2019 Medicine

5. Irreversible Electroporation(IRE) For Unresectable Laryngeal Neoplasms

Irreversible Electroporation(IRE) For Unresectable Laryngeal Neoplasms Irreversible Electroporation(IRE) For Unresectable Laryngeal Neoplasms - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Irreversible (...) Electroporation(IRE) For Unresectable Laryngeal Neoplasms (IRE) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT02430675 Recruitment Status : Recruiting First Posted : April 30, 2015 Last Update Posted : March 29, 2016 See Sponsor

2015 Clinical Trials

6. Prades J-M et al. Randomized phase III trial comparing induction chemotherapy followed by radiotherapy to concomitant chemoradiotherapy for laryngeal preservation in T3Mo pyriform sinus carcinoma. Acta Oto-Laryngol 2010; 130: 150-155. (PubMed)

Prades J-M et al. Randomized phase III trial comparing induction chemotherapy followed by radiotherapy to concomitant chemoradiotherapy for laryngeal preservation in T3Mo pyriform sinus carcinoma. Acta Oto-Laryngol 2010; 130: 150-155. 29532718 2019 02 08 2019 02 15 1651-2251 138 3 2018 Mar Acta oto-laryngologica Acta Otolaryngol. Prades J-M et al. Randomized phase III trial comparing induction chemotherapy followed by radiotherapy to concomitant chemoradiotherapy for laryngeal preservation (...) in T3Mo pyriform sinus carcinoma. Acta Oto-Laryngol 2010; 130: 150-155. 310-316 10.1080/00016489.2018.1438160 Anniko Matti M eng Classical Article Historical Article Journal Article England Acta Otolaryngol 0370354 0001-6489 IM Chemoradiotherapy history Clinical Trials, Phase III as Topic history History, 21st Century Humans Hypopharyngeal Neoplasms drug therapy history radiotherapy Induction Chemotherapy history Neoplasm Staging history Otolaryngology history Pyriform Sinus Randomized Controlled

2019 Acta oto-laryngologica

7. Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve During Thyroidectomy with Adhesive Skin Electrodes. (PubMed)

Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve During Thyroidectomy with Adhesive Skin Electrodes. Alternative methods to overcome limitations of electromyogram (EMG) tube applied for intraoperative neuromonitoring (IONM) of recurrent laryngeal nerve (RLN) during thyroidectomy have been introduced. In this study, we evaluated the feasibility of adhesive skin electrodes for IONM of RLN in patients who underwent thyroidectomy.A total of 39 nerves at risk were prospectively enrolled (...) in this study. Twenty-five patients with papillary thyroid carcinoma, 3 patients with follicular neoplasm, and 2 patients with Graves' disease underwent thyroidectomy. All patients were intubated with EMG tube, and two disposable pre-gelled surface electrodes were attached to skin at both upper margins of thyroid cartilage. We followed the standard procedure of IONM, and the latency (msec) and amplitude (μV) of each signal were recorded prospectively.Intraoperative neuromonitoring using skin adhesive

2019 World Journal of Surgery

8. Oropharyngeal, hypopharyngeal and laryngeal cancer: diagnosis, treatment and follow-up

by the Executive Board (see http://kce.fgov.be/content/the-board). ? Only the KCE is responsible for errors or omissions that could persist. The policy recommendations are also under the full responsibility of the KCE. Publication date: Domain: MeSH: NLM Classification: Language: Format: Legal depot: 13 November 2015 Good Clinical Practice (GCP) Head and Neck Neoplasms; Laryngeal Neoplasms; Pharyngeal Neoplasms; Practice Guideline WE 707 English Adobe® PDF™ (A4) D/2015/10.273/ 104 Copyright: KCE reports (...) Oropharyngeal, hypopharyngeal and laryngeal cancer: diagnosis, treatment and follow-up 2015 www.kce.fgov.be KCE REPORT 256Cs SUMMARY OROPHARYNGEAL, HYPOPHARYNGEAL AND LARYNGEAL CANCER: DIAGNOSIS, TREATMENT AND FOLLOW-UP 2015 www.kce.fgov.be KCE REPORT 256Cs GOOD CLINICAL PRACTICE SUMMARY OROPHARYNGEAL, HYPOPHARYNGEAL AND LARYNGEAL CANCER: DIAGNOSIS, TREATMENT AND FOLLOW-UP VINCENT GRÉGOIRE, ROOS LEROY, PAULINE HEUS, LOTTY HOOFT, FLEUR T. VAN DE WETERING, RENÉ SPIJKER, ROB J.P.M. SCHOLTEN, JOHAN

2015 Belgian Health Care Knowledge Centre

9. Transoral robotic surgery for the treatment of laryngeal chondrosarcoma: A case report. (PubMed)

paraglottic space, with resultant narrowing of the laryngeal airway.The patient underwent awake tracheostomy and transoral robotic subtotal resection of the mass using the Da Vinci surgical system (Intuitive Surgical Inc., Sunnyvale, CA, USA). The vocal folds, ventricular mucosa, and arytenoid cartilage were grossly preserved. Final pathology revealed a low-grade cartilaginous neoplasm consistent with low-grade chondrosarcoma.Chondrosarcoma of the larynx is a rare entity that accounts for roughly 1 (...) % of laryngeal neoplasms. Recent trends in otolaryngology literature and practice suggest that low-grade chondrosarcomas can be effectively treated with organ-preserving, conservative surgery. Transoral robotic surgery offers numerous advantages over both open and endoscopic approaches. To our knowledge, this is the first report in the literature describing the successful use of transoral robotic surgery for the resection of a laryngeal chondrosarcoma.Copyright © 2018 Elsevier Inc. All rights reserved.

2018 American Journal of Otolaryngology

10. Single nucleotide polymorphism rs11614913 associated with CC genotype in miR-196a2 is overrepresented in laryngeal squamous cell carcinoma, but not salivary gland tumors in Polish population (PubMed)

Single nucleotide polymorphism rs11614913 associated with CC genotype in miR-196a2 is overrepresented in laryngeal squamous cell carcinoma, but not salivary gland tumors in Polish population The miRNA-196a2 has shown significance in the development of various neoplasms, including head and neck squamous cell carcinoma (HNSCC). The oncogenic functionality of this miRNA is mediated via its potential to target annexin A1 mRNA, a tumor suppressor gene involved in inhibition of the NF-κB pathway (...) . Interestingly, recent data indicate a susceptibility for aforementioned neoplasms in patients with the CC genotype vs the CT and TT genotypes of the rs11614913 SNP located within the DNA sequence of the miR-196a2 that results in elevated expression of the gene. To further investigate this phenomenon, we genotyped this SNP in 40 patients with laryngeal squamous cell carcinoma (LSCC), the most common tumor of the head and neck region and 60 patients with salivary gland tumors (SGT) that show a yet unexplained

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2018 Journal of applied genetics

11. Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma

: Undecided Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by GengLong Liu, First Affiliated Hospital, Sun Yat-Sen University: salvage surgery recurrent laryngeal carcinoma experience Additional relevant MeSH terms: Layout table for MeSH terms Carcinoma Laryngeal Neoplasms Neoplasms, Glandular and Epithelial Neoplasms by Histologic Type Neoplasms Otorhinolaryngologic Neoplasms Head and Neck Neoplasms (...) Neoplasms by Site Laryngeal Diseases Respiratory Tract Diseases Respiratory Tract Neoplasms Otorhinolaryngologic Diseases

2018 Clinical Trials

12. A Multicenter, Randomized, Case-control Study of Unilateral vs Bilateral Neck Dissection for cN0 Supraglottic Laryngeal Cancer

Intervention/treatment Phase Laryngeal Neoplasms Malignant Neoplasm of Supraglottis Primary Neck Dislocation Procedure: Unilateral Neck Dissection Procedure: Bilateral Neck Dissection Not Applicable Detailed Description: Some retrospective analysises showed the low local recurrence rate of patients who accepted unilateral neck dissection with cN0 supraglottic laryngeal carcinoma. The aim of this study is to see if unilateral dissection can get similar regional control as bilateral dissection. 308 patients (...) -regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Wang Xiaolei, Cancer Institute and Hospital, Chinese Academy of Medical Sciences: clinically negative neck regional control rate Additional relevant MeSH terms: Layout table for MeSH terms Neoplasms Laryngeal Neoplasms Otorhinolaryngologic Neoplasms Head and Neck Neoplasms Neoplasms by Site Laryngeal Diseases Respiratory Tract Diseases Respiratory Tract Neoplasms Otorhinolaryngologic Diseases

2018 Clinical Trials

13. Nomograms to Precisely Predict Conditional Risk of Recurrence for Patients With Laryngeal Cancer

Numbers: Laryngeal carcinoma First Posted: July 23, 2018 Last Update Posted: July 23, 2018 Last Verified: July 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Keywords provided by GengLong Liu, First Affiliated Hospital, Sun Yat-Sen University: risk of recurrence Nomograms Laryngeal cancer Additional relevant MeSH terms: Layout table for MeSH terms Recurrence Laryngeal Neoplasms (...) Disease Attributes Pathologic Processes Otorhinolaryngologic Neoplasms Head and Neck Neoplasms Neoplasms by Site Neoplasms Laryngeal Diseases Respiratory Tract Diseases Respiratory Tract Neoplasms Otorhinolaryngologic Diseases

2018 Clinical Trials

14. Lidocaine Reduces Muscle Tremor is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring

: September 18, 2018 Last Verified: September 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Wounds and Injuries Thyroid Diseases Thyroid Neoplasms Laryngeal Nerve Injuries Recurrent Laryngeal Nerve Injuries Accessory Nerve Injuries Tremor Endocrine System Diseases Endocrine Gland Neoplasms Neoplasms by Site Neoplasms Head and Neck Neoplasms Laryngeal (...) Lidocaine Reduces Muscle Tremor is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring Lidocaine Reduces Muscle Tremor is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2018 Clinical Trials

15. Laryngeal chondrosarcoma, case report and literature review (PubMed)

Laryngeal chondrosarcoma, case report and literature review Chondrosarcoma constitutes 0.2% of all malignant tumors of the larynx. Many surgeons treat it with total laryngectomy due to the limited experience with this neoplasm because its rarity, and although several conservative approaches have been proposed, the data of these techniques are limited and based on retrospective series.A 52-year-old male with a transglottic submucosal tumor and glottic stenosis in fiberoptic examination showed (...) by tomography a laryngeal tumor that infiltrates vocal cords, glottis, cricoid and thyroid cartilage of 3 × 2.7 × 4 cm. Patient was submitted to total laryngectomy with selective bilateral neck dissection because obstructive tumor. Pathology reported a cricoid cartilage tumor consistent with grade 2 chondrosarcoma.Biopsy by laryngoscopy is considered the standard procedure for the diagnosis of laryngeal tumors, however the need for general anesthesia and the difficulty in intubation in some patients

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2018 International journal of surgery case reports

16. Nomograms to Precisely Predict Conditional Risk of Survival for Patients With Laryngeal Cancer

Update Posted: November 27, 2018 Last Verified: November 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by GengLong Liu, First Affiliated Hospital, Sun Yat-Sen University: Survival Nomograms Laryngeal cancer Additional relevant MeSH terms: Layout table for MeSH terms Laryngeal Neoplasms Otorhinolaryngologic (...) Neoplasms Head and Neck Neoplasms Neoplasms by Site Neoplasms Laryngeal Diseases Respiratory Tract Diseases Respiratory Tract Neoplasms Otorhinolaryngologic Diseases

2018 Clinical Trials

17. Intralesional Cidofovir for Treatment of Acyclovir-Resistant Laryngeal Herpes Manifesting as Supraglottic Mass. (PubMed)

Intralesional Cidofovir for Treatment of Acyclovir-Resistant Laryngeal Herpes Manifesting as Supraglottic Mass. Laryngopharyngeal herpes simplex virus infection is rare and presents typically in the supraglottis. Findings on presentation can range from small mucosal lesions to fungating obstructive masses mimicking neoplasm. Laryngopharyngeal herpes is a medically treated disease.Identify potential treatment in cases that are refractory to antiviral medications.Individual case with treatment (...) adapted from other case report.We report a case of bulky, obstructive supraglottic and glottic herpes virus laryngitis that presented with dysphonia, dysphagia, and airway complaints resistant to acyclovir analogues that was treated effectively with intralesional cidofovir injection.Our promising initial response suggests a potential novel treatment for this unusual condition.

2018 Rhinology and Laryngology

18. Vocal-cord vs. Complete Laryngeal Radiotherapy for Early Glottic Cancer

Product Not Approved or Cleared by U.S. FDA: No Pediatric Postmarket Surveillance of a Device Product: No Product Manufactured in and Exported from the U.S.: No Additional relevant MeSH terms: Layout table for MeSH terms Laryngeal Neoplasms Otorhinolaryngologic Neoplasms Head and Neck Neoplasms Neoplasms by Site Neoplasms Laryngeal Diseases Respiratory Tract Diseases Respiratory Tract Neoplasms Otorhinolaryngologic Diseases (...) Vocal-cord vs. Complete Laryngeal Radiotherapy for Early Glottic Cancer Vocal-cord vs. Complete Laryngeal Radiotherapy for Early Glottic Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Vocal-cord vs

2018 Clinical Trials

19. Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve During Thyroid Surgery

Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve During Thyroid Surgery Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve During Thyroid Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve During Thyroid Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2018 Clinical Trials

20. Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review. (PubMed)

that dyspnea was significantly relieved.The case report shows the imaging features of cricoid cartilage invasion, including F-FDG PET/CT, 18F-sodium fluoride positron emission tomography-computed tomography (F-NaF PET-CT), and 3D PET-CT. Precise understanding of the invasion scope, accurately staging of laryngeal carcinoma, and choosing of the most suitable surgical scheme are the factors that lead to the optimal treatment of laryngeal neoplasms. (...) Elevated 18F-NaF uptake in cricoid cartilage in a patient with laryngeal carcinoma: A case report and literature review. Laryngeal cancer is aggressive tumor that arises from the tissues of the larynx. Although any bone can be affected, involvement of cricoid cartilage was reported very rarely, and there has been no report of 18F-sodium fluoride positron emission tomography-computed tomography (F-NaF PET-CT) and 3D PET-CT for the evaluation of cricoid cartilage invasion.A 54-year-old male

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2017 Medicine

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