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234 results for

Lactose Breath Hydrogen Test

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221. Low-dose lactose in drugs neither increases breath hydrogen excretion nor causes gastrointestinal symptoms. (Abstract)

Low-dose lactose in drugs neither increases breath hydrogen excretion nor causes gastrointestinal symptoms. Despite the reported tolerance to a low dose of lactose, many lactose malabsorbers follow a rigorous lactose-free diet also avoiding lactose-containing drugs. Up to now, only a few case reports have described the onset of gastrointestinal symptoms in lactose malabsorbers following the ingestion of these drugs. It has been suggested that capsules/tablets contain no more than 400 mg (...) of lactose.To evaluate breath H(2) excretion and intolerance symptoms after ingestion of a capsule containing 400 mg of lactose or placebo through a randomized, cross-over, double-blind, controlled study.Seventy-seven lactose maldigesters with intolerance underwent two H2 breath tests with both 400 mg of lactose and 400 mg of placebo. Gastrointestinal symptoms occurring in the 8 h following the ingestion of different substrates were evaluated by a visual-analogue scale.Ingestion of 400 mg of lactose did

2008 Alimentary pharmacology & therapeutics Controlled trial quality: uncertain

222. Breath hydrogen test and stools characteristics after ingestion of milk and yogurt in malnourished children with chronic diarrhoea and lactase deficiency. (Abstract)

Breath hydrogen test and stools characteristics after ingestion of milk and yogurt in malnourished children with chronic diarrhoea and lactase deficiency. 3669132 1987 11 27 2018 05 31 0142-6338 33 4 1987 08 Journal of tropical pediatrics J. Trop. Pediatr. Breath hydrogen test and stools characteristics after ingestion of milk and yogurt in malnourished children with chronic diarrhoea and lactase deficiency. 177-80 10.1093/tropej/33.4.177 Dewit O O Boudraa G G Touhami M M Desjeux J F JF eng (...) Clinical Trial Comparative Study Journal Article Randomized Controlled Trial England J Trop Pediatr 8010948 0142-6338 IM Animals Breath Tests Child, Preschool Dairy Products Diarrhea, Infantile metabolism Feces analysis Humans Infant Intestinal Absorption Lactose Intolerance metabolism Male Milk Nutrition Disorders metabolism Yogurt 1987 8 1 2000 5 12 9 0 1987 8 1 0 0 ppublish 3669132 10.1093/tropej/33.4.177

1987 Journal of tropical pediatrics Controlled trial quality: uncertain

223. Hydrogen breath test in gastroenteritis. Full Text available with Trip Pro

Hydrogen breath test in gastroenteritis. 7103553 1982 09 24 2018 11 13 1468-2044 57 7 1982 Jul Archives of disease in childhood Arch. Dis. Child. Hydrogen breath test in gastroenteritis. 561-2 Robb T A TA Davidson G P GP eng Letter England Arch Dis Child 0372434 0003-9888 7YNJ3PO35Z Hydrogen AIM IM Breath Tests Gastroenteritis diagnosis Humans Hydrogen analysis Lactose Intolerance diagnosis 1982 7 1 1982 7 1 0 1 1982 7 1 0 0 ppublish 7103553 PMC1627680 Lancet. 1976 Jan 17;1(7951):119-20 54637

1982 Archives of Disease in Childhood

224. Hydrogen breath test in schoolchildren. Full Text available with Trip Pro

Hydrogen breath test in schoolchildren. The frequency of negative hydrogen breath tests due to colonic bacterial flora which are unable to produce hydrogen was determined after oral lactulose challenge in 98 healthy Dutch schoolchildren. There was a negative result in 9.2%. The probability of a false normal lactose breath test (1:77) was calculated from these results together with those from a separate group of children with lactose malabsorption (also determined by hydrogen breath test (...) ). A study of siblings and mothers of subjects with a negative breath test did not show familial clustering of this condition. Faecal incubation tests with various sugars showed an increase in breath hydrogen greater than 100 parts per million in those with a positive breath test while subjects with a negative breath test also had a negative faecal incubation test. The frequency of a false negative hydrogen breath test was higher than previously reported, but this does not affect the superiority

1985 Archives of Disease in Childhood

225. Acidic colonic microclimate--possible reason for false negative hydrogen breath tests. Full Text available with Trip Pro

tests after MgSO4 pretreatment. MgSO4 pretreatment neither resulted in false positive lactose hydrogen breath tests in five lactose tolerant hydrogen producers, nor increased the hydrogen exhalation in five additional hydrogen producing controls after ingestion of lactulose. The results of these studies confirm that hydrogen production from lactulose decreases when the colonic pH is lower (lactulose pretreatment), and increases when colonic pH is higher (MgSO4 pretreatment). In low hydrogen (...) Acidic colonic microclimate--possible reason for false negative hydrogen breath tests. About 5% of normal subjects fail to produce increased hydrogen breath concentration after ingestion of the non-digestible carbohydrate lactulose (low hydrogen producers). The existence of low hydrogen producers limits the diagnostic use of hydrogen (H2) breath tests. We studied the effects of lactulose and of magnesium sulphate (MgSO4) pretreatment on stool-pH and on hydrogen exhalation after oral loading

1988 Gut

226. Inulin is an ideal substrate for a hydrogen breath test to measure the orocaecal transit time. (Abstract)

Inulin is an ideal substrate for a hydrogen breath test to measure the orocaecal transit time. A better substrate is needed for a hydrogen breath test to measure the orocaecal transit time. The currently used substrate, lactulose, accelerates the orocaecal transit time by increasing the osmolality of the gut contents. The recently developed lactose 13C-ureide breath test is reliable, but a hydrogen breath test is preferred, as it allows the simultaneous investigation of the digestion (...) ; interquartile range, 300-383 min) and lactose 13C-ureide (353 min; interquartile range, 285-375 min) (r=0.85; P<0.001). The administration of 5 or 10 g Raftilin HP had no influence on the orocaecal transit time, whereas lactulose significantly shortened the orocaecal transit time. Neither inulin nor lactulose had a significant influence on gastric emptying or protein or lipid assimilation.Raftilin HP is an ideal substrate for a hydrogen breath test to measure the orocaecal transit time.

2003 Alimentary pharmacology & therapeutics Controlled trial quality: uncertain

227. Effect of a single dose of lactase on symptoms and expired hydrogen after lactose challenge in lactose-intolerant subjects. (Abstract)

Effect of a single dose of lactase on symptoms and expired hydrogen after lactose challenge in lactose-intolerant subjects. The effect of a single dose or oral lactase on symptoms, breath hydrogen concentration, and glucose absorption in lactose-intolerant subjects challenged with lactose was studied. Volunteers underwent a lactose challenge test; those whose breath hydrogen concentrations increased 20 ppm or more and who met other criteria were admitted as subjects. After fasting, the subjects (...) were given three chewable lactase tablets (total lactase dose, 9900 FCC units) or placebo tablets in a randomized, double-blind, crossover manner. The subjects also consumed 8 oz of whole milk in which 37.5 g of lactose powder was dissolved (total lactose content, 50 g). The washout period between lactose challenges was at least one week. Breath hydrogen and plasma glucose concentrations were measured before and at intervals after the challenges, and the subjects completed symptom-evaluation

1992 Clinical pharmacy Controlled trial quality: uncertain

228. What is the hydrogen breath test used for? Does it have a use in the diagnosis of lactose intolerance? What is its sensitivity and specificity? Does goat’s milk contain lactose?

What is the hydrogen breath test used for? Does it have a use in the diagnosis of lactose intolerance? What is its sensitivity and specificity? Does goat’s milk contain lactose? What is the hydrogen breath test used for? Does it have a use in the diagnosis of lactose intolerance? What is its sensitivity and specificity? Does goat’s milk contain lactose? - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY (...) test used for? Does it have a use in the diagnosis of lactose intolerance? What is its sensitivity and specificity? Does goat’s milk contain lactose? Gp notebook (1) notes: “The breath hydrogen test may be used to diagnose the malabsorption of specific carbohydrates. Sugars malabsorbed in the small bowel are metabolised by colonic bacteria with the production of hydrogen. The hydrogen diffuses rapidly across the colonic mucosa into the blood and can be measured in the breath. The test is most

2004 TRIP Answers

229. Chronic consumption of fresh but not heated yogurt improves breath-hydrogen status and short-chain fatty acid profiles: a controlled study in healthy men with or without lactose maldigestion. Full Text available with Trip Pro

and Streptococcus thermophilus) on plasma glucose, insulin, triacylglycerols, cholesterol, fatty acids, and short-chain fatty acids.Two groups of 12 healthy men with or without lactose malabsorption were selected with use of a breath-hydrogen test after a 30-g lactose load. Subjects were randomly assigned in a crossover design to 500 g/d of either fresh or heated yogurt for 2 periods of 15 d each, separated by a 15-d washout interval.Chronic consumption of fresh or heated yogurt had no detrimental effects (...) Chronic consumption of fresh but not heated yogurt improves breath-hydrogen status and short-chain fatty acid profiles: a controlled study in healthy men with or without lactose maldigestion. Ingestion of fermented dairy products induces changes in the equilibrium and metabolism of the intestinal microflora and may thus have beneficial effects on the host.We compared the effects of chronic consumption of yogurt with (fresh) or without (heated) live bacterial cultures (Lactobacillus bulgaricus

2000 The American journal of clinical nutrition Controlled trial quality: uncertain

230. Hydrogen breath test for diagnosis of lactose malabsorption: The importance of timing and the number of breath samples Full Text available with Trip Pro

Hydrogen breath test for diagnosis of lactose malabsorption: The importance of timing and the number of breath samples The hydrogen breath test (H(2)BT) is the most widely used procedure in the diagnostic workup of lactose malabsorption and lactose intolerance.To establish whether a simplified two- or three-sample test may reduce time, costs and staff resources without reducing the sensitivity of the procedure.Data from 1,112 patients (292 men, 820 women) with a positive 4 h, nine-sample H(2)BT (...) were retrospectively analyzed. Patients were stratified according to the degree of lactose malabsorption, the occurrence and type of symptoms. Loss of sensitivity in the procedure was evaluated taking into account two-sample tests (0 min and 120 min or 0 min and 210 min) or three-sample tests (0 min, 120 min and 180 min or 0 min, 120 min and 210 min).Using a two-sample test (0 min and 120 min or 0 min and 210 min) the false-negative rate was 33.4% and 22.7%, respectively. With a three-sample test

2006 Canadian Journal of Gastroenterology

231. Correlation between symptoms developed after the oral ingestion of 50g lactose and results of hydrogen breath testing for lactose intolerance. Full Text available with Trip Pro

Correlation between symptoms developed after the oral ingestion of 50g lactose and results of hydrogen breath testing for lactose intolerance. Lactase deficiency is a common condition responsible for various abdominal symptoms. Lactose hydrogen breath test is currently the gold standard in diagnosing lactose intolerance.To assess sensitivity and specificity of symptoms developed after oral lactose challenge.Intensity of nausea, abdominal pain, borborygmi, bloating and diarrhoea was recorded (...) every 15 min up to 3 h after ingestion of 50 g lactose in patients with positive (i.e. breath H2-concentration > or =20 p.p.m. above baseline) and negative lactose hydrogen breath test.Between July 1999 and December 2005, 1127 patients (72% females) underwent lactose hydrogen breath test. A positive result was found in 376 (33%). Sensitivity of individual symptoms ranged from 39% (diarrhoea) to 70% (bloating) while specificity ranged from 69% (bloating) to 90% (diarrhoea). A positive lactose

2008 Alimentary Pharmacology & Therapeutics

232. Breath testing to evaluate lactose intolerance in irritable bowel syndrome correlates with lactulose testing and may not reflect true lactose malabsorption. (Abstract)

lactose breath test and LTT (kappa = 0.29). However, lactose breath test hydrogen levels >166 ppm were universally predictive of abnormal LTT. Finally, a significant correlation was seen between the hydrogen production on lactose and lactulose breath test (r = 0.56, p = 0.01).Lactose breath testing in IBS subjects does not seem to reflect malabsorption; it may be an indicator of abnormal lactulose breath test, suggesting bacterial overgrowth. (...) Breath testing to evaluate lactose intolerance in irritable bowel syndrome correlates with lactulose testing and may not reflect true lactose malabsorption. An increased prevalence of lactose intolerance is seen in irritable bowel syndrome (IBS). Recently, we demonstrated a high prevalence of abnormal lactulose breath test results in IBS suggesting bacterial overgrowth. Because symptoms of lactose intolerance result from bacterial fermentation, the purpose of this study was to determine whether

2003 American Journal of Gastroenterology

233. Effect of fiber on breath hydrogen response and symptoms after oral lactose in lactose malabsorbers. (Abstract)

Effect of fiber on breath hydrogen response and symptoms after oral lactose in lactose malabsorbers. The effect of ingesting cellulose, pectin, and psyllium with orally administered lactose in water or milk was tested in six lactose malabsorbers. Breath hydrogen tests were used to evaluate lactose malabsorption and mouth-to-cecum transit times. Addition of psyllium significantly reduced the breath hydrogen response, and symptoms in each subject; whereas, less diminution of expired hydrogen

1982 The American journal of clinical nutrition Controlled trial quality: uncertain

234. Lactose malabsorption during gastroenteritis, assessed by the hydrogen breath test. Full Text available with Trip Pro

Lactose malabsorption during gastroenteritis, assessed by the hydrogen breath test. Thirty-eight infants and young children with gastroenteritis were investigated for lactose malabsorption. Each of them was given an oral lactose load of either 0.5 g/kg or 2 g/kg after which breath hydrogen excretion was measured, and each was observed to see if he had clinical symptoms of lactose intolerance. Only one patient, given 2 g/kg lactose, had clinical intolerance. His breath hydrogen excretion however (...) was negative. Three of 18 patients given 0.5 g/kg lactose had positive breath hydrogen tests. None of these was symptomatic. Lactose intolerance in gastroenteritis was rare in our study, and the hydrogen breath test was not an appropriate technique for detecting it.

1981 Archives of Disease in Childhood

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