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Lactation for Infant with Cleft Lip or Palate

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1. The Use of Pre-Surgical Nasoalveolar Molding (PNAM) in Unilateral Cleft Lip and Palate Patients Reduces Width of Alveolar Cleft

The Use of Pre-Surgical Nasoalveolar Molding (PNAM) in Unilateral Cleft Lip and Palate Patients Reduces Width of Alveolar Cleft UTCAT3327, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title The Use of Pre-Surgical Nasoalveolar Molding (PNAM) in Unilateral Cleft Lip and Palate Patients Reduces Width of Alveolar Cleft Clinical Question In patients with unilateral cleft lip and palate, does the use of pre-surgical (...) nasoalveolar molding (PNAM) therapy reduce the width of the alveolar cleft? Clinical Bottom Line The use of pre-surgical nasoalveolar molding in unilateral cleft lip and palate patients reduces the alveolar cleft width. This is supported by a randomized controlled trial including 120 patients (60 controls) and a case control study with 30 patients. All patients studied were previously diagnosed with unilateral cleft lip and palate and were shown to have a significant reduction in intersegmental distances

2018 UTHSCSA Dental School CAT Library

3. Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients. (PubMed)

Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients. Cleft lip and palate is one of the most common birth defects and can cause difficulties with feeding, speech and hearing, as well as psychosocial problems. Treatment of orofacial clefts is prolonged; it typically commences after birth and lasts until the child reaches adulthood or even into adulthood. Residual deformities, functional disturbances, or both, are frequently seen in adults (...) National Institutes of Health Trials Registry (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform were searched for ongoing trials. No restrictions were placed on the language or date of publication when searching the electronic databases.We included randomised controlled trials (RCTs) comparing maxillary distraction osteogenesis to conventional Le Fort I osteotomy for the correction of cleft lip and palate maxillary hypoplasia in non-syndromic cleft

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2018 Cochrane

4. Cleft lip and palate

Cleft lip and palate Cleft lip and palate - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Cleft lip and palate Last reviewed: February 2019 Last updated: January 2018 Summary Oro-facial clefts are among the most common birth defects. Cleft lip with or without cleft palate is approximately twice as common as isolated cleft palate. The majority of cleft lip deformities are associated with a varying degree of nasal (...) deformity. Oro-facial clefts can occur in isolation or as a component of an identifiable syndrome. The aetiology of cleft lip and palate involves a variety of genetic and environmental factors that result in variable expressions of oro-facial clefting. Comprehensive care involves a multi-disciplinary cleft team with specialists from fields such as facial plastic surgery, genetics, nursing, speech-language pathology, orthodontics, dentistry, oral surgery, audiology, and paediatrics. Definition An oro

2018 BMJ Best Practice

5. Guidelines for Breastfeeding Infants with Cleft Lip, Cleft Palate, or Cleft Lip and Palate

Guidelines for Breastfeeding Infants with Cleft Lip, Cleft Palate, or Cleft Lip and Palate ABM Protocol ABM Clinical Protocol #17: Guidelines for Breastfeeding Infants with Cleft Lip, Cleft Palate, or Cleft Lip and Palate, Revised 2013 Sheena Reilly, 1,2 Julie Reid, 1,3 Jemma Skeat, 2 Petrea Cahir, 1 Christina Mei, 2 Maya Bunik, 4 and the Academy of Breastfeeding Medicine A central goal of the Academy of Breastfeeding Medicine is the development of clinical protocols for managing common medical (...) problems that may impact breastfeeding success. These protocols serve only as guidelines for the care of breast- feeding mothers and infants and do not delineate an exclusive course of treatment or serve as standards of medical care. Variations in treatment may be appropriate according to the needs of an individual patient. De?nitions W hen a cleft lip(CL) occurs, thelipisnotcontiguous, and when a cleft palate (CP) occurs, there is communi- cation between the oral and nasal cavities. 1 Clefts can range

2013 Academy of Breastfeeding Medicine

6. Dentists Treating Cleft Lip and/or Palate Patients Will Need to Consider Anatomical Variations when Delivering Local Anesthetic

Dentists Treating Cleft Lip and/or Palate Patients Will Need to Consider Anatomical Variations when Delivering Local Anesthetic UTCAT3331, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Dentists Treating Cleft Lip and/or Palate Patients Will Need to Consider Anatomical Variations when Delivering Local Anesthetic Clinical Question In cleft lip and palate patients, will altered anesthetic techniques be more effective (...) than standard techniques in achieving adequate pain control? Clinical Bottom Line Low evidence to support minor alterations needed that include first anesthetize away from cleft and then at cleft margins. But similarities include the use of topical anesthetic and the guidance for slow injection. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Trindade-Suedam/2012 2 patients with cleft palate and lip

2018 UTHSCSA Dental School CAT Library

7. Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients. (PubMed)

Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients. Cleft lip and palate is one of the most common birth defects and can cause difficulties with feeding, speech and hearing, as well as psychosocial problems. Treatment of orofacial clefts is prolonged; it typically commences after birth and lasts until the child reaches adulthood or even into adulthood. Residual deformities, functional disturbances, or both, are frequently seen in adults (...) February 2016). There were no restrictions regarding language or date of publication in the electronic searches. We performed handsearching of six speciality journals and we checked the reference lists of all trials identified for further studies.We included randomised controlled trials (RCTs) comparing maxillary distraction osteogenesis to conventional Le Fort I osteotomy for the correction of cleft lip and palate maxillary hypoplasia in non-syndromic cleft patients aged 15 years or older.Two review

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2016 Cochrane

8. The Difference in Cervical Vertebral Skeletal Maturation between Cleft Lip/Palate and Non-Cleft Lip/Palate Orthodontic Patients (PubMed)

The Difference in Cervical Vertebral Skeletal Maturation between Cleft Lip/Palate and Non-Cleft Lip/Palate Orthodontic Patients The aim was to evaluate differences in the cervical vertebral skeletal maturity of unilateral cleft lip and palate (UCLP) and non-cleft lip/palate (non-CLP) Saudi male orthodontic patients.This cross-sectional multicenter study took place at the dental school, King Saud University and King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, between (...) was significantly earlier in the non-cleft participants in comparison with the UCLP participants (p = 0.009).There is delayed skeletal maturity among the UCLP Saudi male population in comparison with their non-CLP age-matched peers.

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2018 BioMed research international

9. A Comparative Study of Oral Microbiota in Infants with Complete Cleft Lip and Palate or Cleft Soft Palate (PubMed)

A Comparative Study of Oral Microbiota in Infants with Complete Cleft Lip and Palate or Cleft Soft Palate Few reports have been published on the early microbiota in infants with various types of cleft palate. We assessed the formation of the oral microbiota in infants with complete cleft lip and palate (CLP n = 30) or cleft soft palate (CSP n = 25) in the neonatal period (T1 time) and again in the gum pad stage (T2 time). Culture swabs from the tongue, palate, and/or cleft margin at T1 and T2 (...) . aureus MSSA, Staphylococcus epidermidis, and members of the Enterobacteriaceae family were noted in CLP infants compared to the CSP. S. mitis and Streptococcus sanguinis appeared with the greatest frequency on the tongue, whereas Streptococcus salivarius was predominant on the palate. The development of the microbiota in CLP subjects was characterised by a significant increase in the prevalence of pathogenic bacteria.

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2017 BioMed research international

10. Usefulness of Airway Scope for intubation of infants with cleft lip and palate-comparison with Macintosh laryngoscope: a randomized controlled trial. (PubMed)

Usefulness of Airway Scope for intubation of infants with cleft lip and palate-comparison with Macintosh laryngoscope: a randomized controlled trial. Airway Scope (AWS) with its plastic blade does not require a head-tilt or separate laryngoscopy to guide intubations. Therefore, we hypothesized that its use would reduce the intubation time (IT) and the frequency of airway complication events when compared with the use of Macintosh Laryngoscope (ML) for infants with cleft lip and palate (CLP (...) related to extensive clefts. Airway complications were detected in ML group.AWS could be useful for intubation of infants with CLP; it required IT similar to that required using ML, with a lower rate of airway complications.UMIN-CTR Registration number UMIN000024763 . Registered 8 November 2016.

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2019 BMC Anesthesiology

11. Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate. (PubMed)

Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate. Secondary alveolar bone grafting has been widely used to reconstruct alveolar cleft. However, there is still some controversy.To compare the effectiveness and safety of different secondary bone grafting methods.The final electronic and handsearches were carried out on 11 February 2011, and included the Cochrane Oral Health Group's Trials Register, Cochrane Central Register of Controlled Trials (...) , MEDLINE, EMBASE, Chinese Biomedical Literature Database and WHO International Clinical Trials Registry Platform. All the Chinese professional journals in the oral and dental field were handsearched and conference proceedings consulted. There was no language or time restriction.Only randomized clinical trials were selected. Patients with the diagnosis of cleft lip and alveolar process only, unilateral cleft lip and palate and bilateral cleft lip and palate involving the alveolar process and greater

2011 Cochrane

12. The role of speech therapy for improving the speech of children with cleft lip and/or cleft palate: a systematic review and meta-analysis

The role of speech therapy for improving the speech of children with cleft lip and/or cleft palate: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO

13. Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only (PubMed)

Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is among the most common human birth defects with multifactorial etiology. Here, we present results from a genome-wide imputation study of nsCL/P in which, after adding replication cohort data, four novel risk loci for nsCL/P are identified (at chromosomal regions 2p21, 14q22 (...) % contributed to by the 24 risk loci known to date. For each of these, we identify credible SNPs using a Bayesian refinement approach, with two loci harbouring only one probable causal variant. Finally, we demonstrate that there is no polygenic component of nsCL/P detectable that is shared with nonsyndromic cleft palate only (nsCPO). Our data suggest that, while common variants are strongly contributing to risk for nsCL/P, they do not seem to be involved in nsCPO which might be more often caused by rare

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2017 Human molecular genetics

14. Lactation for Infant with Cleft Lip or Palate

Lactation for Infant with Cleft Lip or Palate Lactation for Infant with Cleft Lip or Palate Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer (...) Administration 4 Lactation for Infant with Cleft Lip or Palate Lactation for Infant with Cleft Lip or Palate Aka: Lactation for Infant with Cleft Lip or Palate , Breast Feeding for Infant with Cleft Lip , Breast Feeding for Infant with Cleft Palate From Related Chapters II. Benefits: Breast Feeding is very advantageous in this group Lower infection risk before and after repair Strengthens facial muscles and eases repair III. Management: Suggestions Consider Palatal obturator plate Plastic dental appliance

2018 FP Notebook

15. Non-Syndromic Patients With Cleft Lip And/Or Palate (CLP) Tend To Have Higher Caries Prevalence Than Non-CLP Patients

Non-Syndromic Patients With Cleft Lip And/Or Palate (CLP) Tend To Have Higher Caries Prevalence Than Non-CLP Patients UTCAT2989, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Non-Syndromic Patients With Cleft Lip And/Or Palate (CLP) Tend To Have Higher Caries Prevalence Than Non-CLP Patients Clinical Question In patients with non-syndromic cleft lip/cleft palate, is there greater predisposition to caries than in non (...) -CL/P patients? Clinical Bottom Line Non-syndromic patients with cleft lip and/or palate tend to have higher caries prevalence than non-CLP patients. This is supported by a meta-analysis of several cross-sectional trials in which the decayed, missing, and filled (DMF) index was significantly higher for CLP patients than non-CLP patients. This would suggest that dentists should factor in CLP while determining caries risk status for patients. Best Evidence (you may view more info by clicking

2016 UTHSCSA Dental School CAT Library

16. Investigation of candidate genes of non-syndromic cleft lip with or without cleft palate, using both case-control and family-based association studies. (PubMed)

Investigation of candidate genes of non-syndromic cleft lip with or without cleft palate, using both case-control and family-based association studies. Non-syndromic cleft of the lip and/or palate (NSCL/P) is one of the most common polygenic diseases. In this study, both case-control and family-based association study were used to confirm whether the Single Nucleotide Polymorphisms (SNPs) were associated with NSCL/P.A total of 37 nuclear families and 189 controls were recruited, whose blood DNA

2019 Medicine

17. Influence of timing of delayed hard palate closure on articulation skills in 3-year-old Danish children with unilateral cleft lip and palate. (PubMed)

Influence of timing of delayed hard palate closure on articulation skills in 3-year-old Danish children with unilateral cleft lip and palate. Differing results regarding articulation skills in young children with cleft palate (CP) have been reported and often interpreted as a consequence of different surgical protocols.To assess the influence of different timing of hard palate closure in a two-stage procedure on articulation skills in 3-year-olds born with unilateral cleft lip and palate (UCLP (...) participants had the lip and soft palate closed around 4 months of age. Audio and video recordings of a naming test were available from 113 children (32 girls and 81 boys) and were transcribed phonetically. Recordings were obtained prior to hard palate closure in the LHPC group. The main outcome measures were percentage consonants correct adjusted (PCC-A) and consonant errors from blinded assessments. Results from 36 Danish-speaking children without CP obtained previously by Willadsen in 2012 were used

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2019 International Journal of Language & Communication Disorders

18. Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. (PubMed)

Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. Nonsyndromic orofacial clefts (OFCs) are a heterogeneous group of common craniofacial birth defects with complex etiologies that include genetic and environmental risk factors. OFCs are commonly categorized as cleft lip with or without cleft palate (CL/P) and cleft palate alone (CP), which have historically been

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2018 Human Genetics

19. Cleft lip and palate: maxillary distraction osteogenesis or orthognathic surgery for hypoplastic maxilla?

Cleft lip and palate: maxillary distraction osteogenesis or orthognathic surgery for hypoplastic maxilla? Cleft lip and palate: maxillary distraction osteogenesis or orthognathic surgery for hypoplastic maxilla? - National Elf Service Search National Elf Service Search National Elf Service » » » » Cleft lip and palate: maxillary distraction osteogenesis or orthognathic surgery for hypoplastic maxilla? Sep 14 2018 Posted by Cleft lip and palate (CLP) is a common birth defect. The prevalence (...) for the treatment of hypoplastic maxilla in people with cleft lip and palate. Methods Searches were conducted in the Cochrane Oral Health’s Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, LILACS BIREME Virtual Health Library (Latin American and Caribbean Health Science Information database), the US National Institutes of Health Trials Registry (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform

2018 The Dental Elf

20. Epidemiology and clinical profile of individuals with cleft lip and palate utilising specialised academic treatment centres in South Africa. (PubMed)

Epidemiology and clinical profile of individuals with cleft lip and palate utilising specialised academic treatment centres in South Africa. The study was conducted to determine the epidemiology and clinical profile of individuals with cleft lip and/or palate (CLP) utilizing specialized academic treatment centres in South Africa's public health sector.The Human Research Ethics Committee of the University of the Witwatersrand in Johannesburg provided ethical approval for the study. We conducted (...) per 1000 live births, with provincial variation of 0.1/1000 to 1.2/1000. The distribution of clefts was: 35.3% cleft palate; 34.6% cleft lip and palate; 19.0% cleft lip and other cleft anomalies at 2%. Of the total number of CLP, 47.5% were male and 52.5% female, and this difference was statistically significant (p<0.001). The majority of clefts occurred on the left for males (35.5%) and palate for females (43.4%), with a male predominance of unilateral cleft lip and palate (53.3%).The study

2019 PLoS ONE

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