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1. An approach to the assessment of uncertainty of measurement for cellular pathology laboratories

An approach to the assessment of uncertainty of measurement for cellular pathology laboratories PUBS 110515 1 V3 Final ISO 15189:2012 – An approach to the assessment of uncertainty of measurement for cellular pathology laboratories May 2015 Unique document number G146 Document name ISO 15189:2012 – An approach to the assessment of uncertainty of measurement for cellular pathology laboratories Version number 1 Produced by Professor Tim Helliwell, consultant histopathologist; Dr Tom Giles (...) , to provide laboratories with an approach to the assessment of the uncertainty of measurement, an area of quality assurance with which they may be unfamiliar. The document has been discussed with the United Kingdom Accreditation Service (UKAS) assessment team so that we move towards a shared understanding of the most appropriate ways to meet this aspect of the ISO 15189 standard. The document was discussed and agreed at the April 2015 meeting of the SAC for Cellular Pathology and at the meeting

2015 Royal College of Pathologists

2. Laboratory and Pathology Links

Laboratory and Pathology Links Laboratory and Pathology Links Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Laboratory and Pathology (...) Links Laboratory and Pathology Links Aka: Laboratory and Pathology Links II. Resources Internet Pathology Laboratory for Medical Education Tests NIH NCBI Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Laboratory and Pathology Links." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in General About FPnotebook.com is a rapid access, point

2018 FP Notebook

3. SCAI Multi-Society Position Statement on Occupational Health Hazards of the Catheterization Laboratory

to radiation during interventional procedures may be at increased risk to develop these same illnesses. , 1.3 Orthopedic injuries: Collateral damage of working in the fluoroscopic laboratory There is now overwhelming evidence demonstrating that working in the interventional laboratory is associated with an increased incidence of orthopedic illnesses, particularly those related to the cervical and lumbar spine. These orthopedic injuries have been linked to the cumulative effects of bearing the weight (...) laboratory standards: process, protocols, equipment, personnel, and safety . Heart Rhythm . 2014 ; 11 ( 8 ):e9‐e51. 50 Fiorilli PN , Kobayashi T , Giri J , Hirshfeld JW Jr . Strategies for radiation exposure‐sparing in fluoroscopically guided invasive cardiovascular procedures . Catheter Cardiovasc Interv . 2019 ; 93 : 1 ‐ 10 . Online Version of Record before inclusion in an issue Additional links About Wiley Online Library Help & Support Opportunities Connect with Wiley Copyright © 1999-2019 . All

2020 Society for Cardiovascular Angiography and Interventions

4. Laboratory diagnosis of G6PD deficiency Full Text available with Trip Pro

Laboratory diagnosis of G6PD deficiency Laboratory diagnosis of G6PD deficiency. A British Society for Haematology Guideline - Roper - - British Journal of Haematology - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term Guideline Free Access Laboratory diagnosis of G6PD deficiency. A British Society for Haematology Guideline Department of Haematology, Imperial College Healthcare NHS Trust, London (...) NEQAS Haematology, Watford General Hospital, Watford, UK BSH Task Force Representative, London, UK Corresponding Author E-mail address: Correspondence : BSH Administrator, British Society for Haematology, 100 White Lion Street, London, N1 9PF, UK. E‐mail: First published: 28 January 2020 Give access Share full text access Please review our and check box below to share full-text version of article. I have read and accept the Wiley Online Library Terms and Conditions of Use. Shareable Link Use

2020 British Committee for Standards in Haematology

5. Covid-19: RCPath guidance for remote digital pathology

with a lower specification display may represent a higher risk than reporting using the departmental digital pathology system and display. Further guidance on home reporting and recommended minimum specifications can be found in appendix B, which includes a link to access to a point of use QA tool for pathology. The tool tests colour accuracy, not diagnostic accuracy, and may be a useful indicator of the suitability of a particular screen for digital pathology diagnostics, but more work is needed (...) to establish this. Image: A Point of Use QA for pathology (POUQA) [5] See appendix B for the link. The image above is for illustrative purposes only – the live link should be used to test displays 6 4.1.2. Human interface devices and software Pathologists should be aware that the software and “human computer interaction devices” (i.e. mouse/ trackball) used remotely may be different from the software used on site, and this may present a challenge in navigating digital slides (e.g. screening a whole slide

2020 Royal College of Pathologists

6. Laboratory Studies Into the Pathology of Leukaemia

Laboratory Studies Into the Pathology of Leukaemia Laboratory Studies Into the Pathology of Leukaemia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Laboratory Studies Into the Pathology of Leukaemia (...) by (Responsible Party): Royal Marsden NHS Foundation Trust Study Details Study Description Go to Brief Summary: Ongoing laboratory work into the pathology of Leukaemia: Condition or disease Intervention/treatment Leukemia Procedure: Bone Marrow Aspirate Detailed Description: The investigators will test AML samples sent to the diagnostic laboratory from participants with newly diagnosed or relapsed/refractory AML. Samples will be sent from district general hospitals and teaching hospitals. Results

2017 Clinical Trials

7. Handbook on tuberculosis laboratory diagnostic methods in the European Union

Handbook on tuberculosis laboratory diagnostic methods in the European Union TECHNICAL REPORT www.ecdc.europa.eu Handbook on tuberculosis laboratory diagnostic methods in the European Union Updated 2018ECDC TECHNICAL REPORT Handbook on tuberculosis laboratory diagnostic methods in the European Union Updated 2018 ii This report of the European Centre for Disease Prevention and Control (ECDC) was coordinated by Csaba Ködmön with support from Marieke J. van der Werf, Francis Drobniewski (...) and Vladyslav Nikolayevskyy. This report was sent for consultation to the members of the ERLTB-Net network (see Appendix 1 for list of contributors). The first version of this ECDC technical report, previously published as ‘Mastering the basics of TB control: Development of a handbook on TB diagnostic methods’ (Stockholm 2011), concerned the development of the handbook that was included as an annex. This report was revised and renamed ‘Handbook on TB laboratory diagnostic methods in the European Union

2018 European Centre for Disease Prevention and Control - Technical Guidance

8. National minimum retesting intervals in pathology: A final report detailing consensus recommendations for minimum retesting intervals for use in pathology

-exposure to blood borne viruses 54 8 Cellular pathology recommendations 56 8.1 General aspects of laboratory practice (cellular pathology) 56 8.2 Exfoliative and fine needle aspiration cytology 56 8.3 Histopathology 56 9 Contributors 58 CEff 161215 4 V7 Final 1 Introduction There is currently a drive in pathology to harmonise processes and remove unnecessary waste, thereby saving money. In addition, any intervention that acts to reduce waste and avoid unnecessary phlebotomy/booking appointment (...) for the patient can only be seen as contributing to the optimisation of patient care. At a time when many laboratories and providers are implementing electronic requesting of laboratory tests, which allows the requestor and the laboratory to manage what is requested, there needs to be a solution to support this process based on the best available evidence. Similar initiatives have been reported including the work of the Pathology Harmony Group and the recent proposal to standardise test profiles. 1,2 How

2016 Royal College of Pathologists

9. Laboratory and Pathology Books

Books Laboratory and Pathology Books Aka: Laboratory and Pathology Books , Laboratory and Pathology Resources II. Resources: Primary Care Library Recommendations Williamson (2014) Wallach's Interpretation Diagnostic Tests III. Resources: Medical Student Library Recommendations Kumar (2014) Robbins and Cotran Pathology 4th ed., Saunders IV. Resources: Lab Coat Resource Recommendations Bakerman (2002) Bakerman's ABC's of Interpretive Laboratory Data, ILD inc Images: Related links to external sites (...) Laboratory and Pathology Books Laboratory and Pathology Books Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Laboratory and Pathology

2018 FP Notebook

10. Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients

Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients LABORATORY MEDICINE PRACTICE GUIDELINES EDITED BY LORALIE J. LANGMAN AND PAUL J. JANNETTO Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Co-Sponsored byLABORATORY MEDICINE PRACTICE GUIDELINES Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Loralie J. Langman Committee Chair Department of Laboratory Medicine and Pathology Mayo Clinic (...) Rochester, MN Paul J. Jannetto Committee Vice Chair Department of Laboratory Medicine and Pathology Mayo Clinic Rochester, MN Nancy Bratanow Midwest Comprehensive Pain Care Wauwatosa, WI COMMITTEE MEMBERS EDITED BY LORALIE J. LANGMAN AND PAUL J. JANNETTO William A. Clark Department of Pathology Johns Hopkins University School of Medicine Baltimore, MD Robin J. Hamill-Ruth Department of Anesthesiology University of Virginia Health System Charlottesville, VA Catherine A. Hammett-Stabler Department

2018 American Academy of Pain Medicine

11. Standards and guidelines for clinical genetics laboratories - cytogenetics

information that becomes available after that date. It also would be prudent to consider whether intellectual property interests may restrict the performance of certain tests and other procedures. 1 Department of Pathology, Stanford University School of Medicine, Stanford Health Care, Stanford, California, USA; 2 Cytogenetics and Molecular Pathology, Legacy Laboratory Sciences, Legacy Health, Portland, Oregon, USA; 3 Genetics Department, Kaiser Permanente, San Francisco, California, USA; 4 Department (...) of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA; 5 Department of Obstetrics and Gynecology, University of Utah, Intermountain Healthcare University of Utah, Salt Lake City, Utah, USA; 6 Ancestry DNA, Lehi, Utah, USA; 7 Clinical Cytogenetics Laboratory, Laboratory Corporation of America, Research Triangle Park, North Carolina, USA; 8 Cytogenomics, GeneDx, Gaithersburg, Maryland, USA. Correspondence: Athena M. Cherry (acherry@stanfordhealthcare.org) The Board of Directors

2018 American College of Medical Genetics and Genomics

12. Principles and guidance for interpretive external quality assessment schemes in laboratory medicine

to devise guidance that covers such diverse activity. Those schemes are invited to regard those aspects of their work that relate to the performance of individual pathologists as being within the remit of this guidance and to consult with the Steering Committee to discuss whether and how College oversight of their work can be delivered. The current updating of the principles and guidance for interpretive EQA schemes in laboratory medicine incorporates the recommendations in the Pathology Quality (...) to the scheme organiser. The key linking codes to participants’ names may be held by one person, usually a 1 As originally described at http://webarchive.nationalarchives.gov.uk/20130107105354/http://www.dh.gov.uk/en/Publicationsandstatistics/Pub lications/PublicationsPolicyAndGuidance/DH_4068403 and subsequently updated – see https://en.wikipedia.org/wiki/Caldicott_Report 2 This superficially counterintuitive conclusion is easily justified. In a difficult cellular pathology case, failing Prof 131017 7 V1

2017 Royal College of Pathologists

13. A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology Full Text available with Trip Pro

and the American Society for Microbiology J Michael Miller Microbiology Technical Services, LLC, Dunwoody, Georgia Correspondence: J. M. Miller, Microbiology Technical Services, LLC, PO Box 88212, Dunwoody, GA 30338 ( ). Search for other works by this author on: Matthew J Binnicker Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota Search for other works by this author on: Sheldon Campbell Yale University School of Medicine, New Haven (...) , Connecticut Search for other works by this author on: Karen C Carroll Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland Search for other works by this author on: Kimberle C Chapin Department of Pathology, Rhode Island Hospital, Providence Search for other works by this author on: Peter H Gilligan Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill Search for other works by this author on: Mark D Gonzalez Department of Pathology

2018 Infectious Diseases Society of America

14. Burosumab (Crysvita) - X-linked hypophosphataemia/hypophosphatemia

Burosumab (Crysvita) - X-linked hypophosphataemia/hypophosphatemia 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact 14 December 2017 EMA/148319/2018 Committee for Medicinal Products for Human Use (CHMP) Assessment report Crysvita International non-proprietary name: burosumab Procedure No. EMEA/H/C/004275/0000 Note Assessment (...) Results 76 2.5.3. Planned paediatric study 80 2.5.4. Main studies in adults 80 2.5.5. Discussion on clinical efficacy 82 2.5.6. Conclusions on clinical efficacy 84 2.6. Clinical safety 85 Adverse events 87 Serious adverse events and deaths 93 Adverse events of specific interest 94 Laboratory findings 100 Safety in special populations 105 Immunological events 105 Safety related to drug-drug interactions and other interactions 106 Discontinuation due to AES 106 2.6.1. Discussion on clinical safety 106

2018 European Medicines Agency - EPARs

15. Standards for integrated reporting in cellular pathology

investigations into cellular pathology reports to maximise diagnostic value and maintain a clear, auditable link between these data and the primary tissue sample. We recognise that data may be available from diverse professions or several laboratories and will vary considerably in complexity; any changes in clinical practice should therefore be proportionate to the specific clinical context. The aim of this document is to: ? review developments in integrated reporting, including those in other health systems (...) for a modern molecular and cellular pathology service. Technical and programming solutions should therefore be regarded as a priority for LIMS development teams, including scope for integrating an individual patient’s sequential and other linked specimens. 5.4 In the absence of a comprehensive LIMS solution to integration, laboratory staff should consider how they may develop an interim solution using coordinated rather than integrated reporting. As a minimum, reports might indicate that the results

2017 Royal College of Pathologists

16. Standards for integrated reporting in cellular pathology

investigations into cellular pathology reports to maximise diagnostic value and maintain a clear, auditable link between these data and the primary tissue sample. We recognise that data may be available from diverse professions or several laboratories and will vary considerably in complexity; any changes in clinical practice should therefore be proportionate to the specific clinical context. The aim of this document is to: ? review developments in integrated reporting, including those in other health systems (...) for a modern molecular and cellular pathology service. Technical and programming solutions should therefore be regarded as a priority for LIMS development teams, including scope for integrating an individual patient’s sequential and other linked specimens. 5.4 In the absence of a comprehensive LIMS solution to integration, laboratory staff should consider how they may develop an interim solution using coordinated rather than integrated reporting. As a minimum, reports might indicate that the results

2017 Royal College of Pathologists

17. Initiatives to Optimize the Utilization of Laboratory Tests

to sustained change management for behaviour and practices. (Jim Slater, Chief Executive Officer, Diagnostic Services of Manitoba Inc., Winnipeg, MB: personal communication, Aug 2014). Nova Scotia The Nova Scotia Diagnostic Imaging, Pathology & Laboratory Medicine (DIPLM) Initiative is a joint partnership between the province's district health authorities and the Department of Health and Wellness. The DIPLM Initiative is intended to be "an integrated provincial approach to planning services to enhance (...) the Department of Pathology and Laboratory Medicine in 2010 to monitor and evaluate utilization initiatives. 45 Utilization measures within the department include, but are not limited to, reviewing test ordering patterns with physicians, reviewing test utilization guidelines and algorithms, evaluating requests for new tests to be added to the testing menu, and auditing individual physician test ordering patterns. Ontario Health Quality Ontario's Appropriateness Initiative, 46 overseen by a working group

2015 Canadian Agency for Drugs and Technologies in Health - Environmental Scanning

18. Laboratory and Pathology Links

Laboratory and Pathology Links Laboratory and Pathology Links Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Laboratory and Pathology (...) Links Laboratory and Pathology Links Aka: Laboratory and Pathology Links II. Resources Internet Pathology Laboratory for Medical Education Tests NIH NCBI Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Laboratory and Pathology Links." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in General About FPnotebook.com is a rapid access, point

2015 FP Notebook

19. EPIDEMIC OF PATHOLOGIC MYOPIA: What Can Laboratory Studies and Epidemiology Tell Us? (Abstract)

EPIDEMIC OF PATHOLOGIC MYOPIA: What Can Laboratory Studies and Epidemiology Tell Us? To systematically review epidemiologic and laboratory studies on the etiology of high myopia and its links to pathologic myopia.Regular Medline searches have been performed for the past 20 years, using "myopia" as the basic search term. The abstracts of all articles have been scrutinized for relevance, and where necessary, translations of articles in languages other than English were obtained.Systematic review (...) shows that there is an epidemic of myopia and high myopia in young adults in East and Southeast Asia, with similar but smaller trends in other parts of the world. This suggests an impending epidemic of pathologic myopia. High myopia in young adults in East and Southeast Asia is now predominantly associated with environmental factors, rather than genetic background. Recent clinical trials show that the onset of myopia can be reduced by increasing the time children spend outdoors, and methods to slow

2016 Retina

20. Canadian Multicenter Project on Standardization of Programmed Death-Ligand 1 Immunohistochemistry 22C3 Laboratory-Developed Tests for Pembrolizumab Therapy in NSCLC. Full Text available with Trip Pro

Canadian Multicenter Project on Standardization of Programmed Death-Ligand 1 Immunohistochemistry 22C3 Laboratory-Developed Tests for Pembrolizumab Therapy in NSCLC. The programmed death-ligand 1 (PD-L1) immunohistochemistry (IHC) assay is used to select patients for first or second-line pembrolizumab monotherapy in NSCLC. The PD-L1 IHC 22C3 pharmDx assay requires an Autostainer Link 48 instrument. Laboratories without this stainer have the option to develop a highly accurate 22C3 IHC (...) laboratory-developed test (LDT) on other instruments. The Canadian 22C3 IHC LDT validation project was initiated to harmonize the quality of PD-L1 22C3 IHC LDT protocols across 20 Canadian pathology laboratories.Centrally optimized 22C3 LDT protocols were distributed to participating laboratories. The LDT results were assessed against results using reference PD-L1 IHC 22C3 pharmDx. Analytical sensitivity and specificity were assessed using cell lines with varying PD-L1 expression levels (phase 1) and IHC

2020 Journal of Thoracic Oncology

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