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Labor Induction

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2. Success of trial of labor in women with a history of previous cesarean section for failed labor induction or labor dystocia: a retrospective cohort study. (PubMed)

Success of trial of labor in women with a history of previous cesarean section for failed labor induction or labor dystocia: a retrospective cohort study. The rates of cesarean section (CS) are increasing worldwide leading to an increased risk for maternal and neonatal complications in the subsequent pregnancy and labor. Previous studies have demonstrated that successful trial of labor after cesarean (TOLAC) is associated with the least maternal morbidity, but the risks of unsuccessful TOLAC (...) exceed the risks of scheduled repeat CS. However, prediction of successful TOLAC is difficult, and only limited data on TOLAC in women with previous failed labor induction or labor dystocia exists. Our aim was to evaluate the success of TOLAC in women with a history of failed labor induction or labor dystocia, to compare the delivery outcomes according to stage of labor at time of previous CS, and to assess the risk factors for recurrent failed labor induction or labor dystocia.This retrospective

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2019 BMC Pregnancy and Childbirth

3. Practice Advisory: Clinical guidance for integration of the findings of The ARRIVE Trial: Labor Induction versus Expectant Management in Low-Risk Nulliparous Women

Practice Advisory: Clinical guidance for integration of the findings of The ARRIVE Trial: Labor Induction versus Expectant Management in Low-Risk Nulliparous Women Practice Advisory: Clinical guidance for integration of the findings of The ARRIVE Trial: Labor Induction versus Expectant Management in Low-Risk Nulliparous Women - ACOG Menu ▼ Practice Advisory: Clinical guidance for integration of the findings of The ARRIVE Trial: Labor Induction versus Expectant Management in Low-Risk Nulliparous (...) Women Page Navigation ▼ Share: Practice Advisory: Clinical guidance for integration of the findings of The ARRIVE Trial: Labor Induction versus Expectant Management in Low-Risk Nulliparous Women This Practice Advisory has been endorsed by the Society for Maternal-Fetal Medicine. A randomized controlled trial comparing elective induction of labor at 39 weeks gestation with expectant management among low-risk nulliparous women was published in the on August 8, 2018 (1). The study was a large unmasked

2018 American College of Obstetricians and Gynecologists

4. Factors that affect ultrasound-determined labor progress in women undergoing induction of labor. (PubMed)

Factors that affect ultrasound-determined labor progress in women undergoing induction of labor. The traditional approach to assessing labor progress is by digital vaginal examination, however, it is subjective and imprecise. Recent studies have investigated the role of transperineal ultrasonographic assessment of fetal head descent by measuring angle of progression and head-perineum distance.The objective of this study was to evaluate factors that affected labor progress, defined (...) by the transperineal ultrasonographic parameters, in women achieving vaginal delivery.This was a prospective longitudinal study performed in 315 Chinese women with singleton pregnancy undergoing labor induction at term between December 2016 and December 2017. Paired assessment of cervical dilatation and fetal head station by vaginal examination and transperineal ultrasonographic assessment of fetal head descent (para-sagittal angle of progression and head-perineum distance) were made serially following

2019 American Journal of Obstetrics and Gynecology

5. Labor progress determined by ultrasound is different in women requiring Cesarean delivery from those who experience a vaginal delivery following induction of labor. (PubMed)

Labor progress determined by ultrasound is different in women requiring Cesarean delivery from those who experience a vaginal delivery following induction of labor. The diagnosis of labor dystocia is generally determined by the deviation of labor progress, which is assessed by the use of partogram. Recently, intrapartum transperineal ultrasound for the assessment of fetal head descent has been introduced to assess labor progress in the first stage of labor in a more objective and non-invasive (...) way.The objective of the study was to determine the differences in labor progress by the use of serial transperineal ultrasound assessment of fetal head descent between women having vaginal and Cesarean delivery.This was a prospective longitudinal study performed in 315 women with singleton pregnancy undergoing labor induction at term between December 2016 and December 2017. Paired assessment of cervical dilatation and fetal head station by vaginal examination and transperineal ultrasonographic

2019 American Journal of Obstetrics and Gynecology

6. Vaginal assessment and expedited amniotomy in oral misoprostol labor induction in nulliparas: a randomized trial

Vaginal assessment and expedited amniotomy in oral misoprostol labor induction in nulliparas: a randomized trial Labor is induced in 20-30% of maternities, with an increasing trend of use. Labor induction with oral misoprostol is associated with reduced risk of cesarean deliveries and has a safety and effectiveness profile comparable to those of mechanical methods such as Foley catheter use. Labor induction in nulliparous women continues to be challenging, with the process often quite (...) protracted. The eventual cesarean delivery rate is high, particularly when the cervix is unfavorable and ripening is required. Vaginal examination can cause discomfort and emotional distress particularly to nulliparous women, and plausibly can affect patient satisfaction with the induction and birth process.The aim of this study was to evaluate regular (4-hourly prior to each oral misoprostol dose with amniotomy when feasible) compared with restricted (only if indicated) vaginal assessments during labor

2019 EvidenceUpdates

7. Increased labor induction and women presenting with decreased or altered fetal movements - a population-based survey. (PubMed)

Increased labor induction and women presenting with decreased or altered fetal movements - a population-based survey. Women's awareness of fetal movements is important as perception of decreased fetal movements can be a sign of a compromised fetus. We aimed to study rate of labor induction in relation to number of times women seek care due to decreased or altered fetal movements during their pregnancy compared to women not seeking such care. Further, we investigated the indication (...) of induction.A prospective population-based cohort study including all obstetric clinics in Stockholm, Sweden. Questionnaires were distributed to women who sought care due to decreased or altered fetal movements ≥ 28 week's gestation in 2014, women for whom an examination did not indicate a compromised fetus that required induction of labor or cesarean section when they sought care. Women who gave birth at ≥ 28 weeks' gestation in 2014 in Stockholm comprises the reference group.Labor was induced more often

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2019 PLoS ONE

8. Comparison of outcomes between induction of labor and spontaneous labor for term breech - A systemic review and meta analysis.

Comparison of outcomes between induction of labor and spontaneous labor for term breech - A systemic review and meta analysis. Few studies have assessed the impact of induction of labor on breech presentation. This study aims to summarize the effect of induction of labor of breech presentation on perinatal morbidity.Literature review was done in Medline, Embase, Web of science and Cochrane Library up to 20 October 2017. Randomized control studies, cohort studies, and case control publishing (...) studies comparing induction of labor versus spontaneous labor of singleton live breech birth were included. Perinatal morbidity was calculated by RevMan 5 and presented by pooled odds ratio with 95% confidence intervals.Cesarean section rate and neonatal intensive care unit admission were increased in induction of breech labor as compared with spontaneous breech labor. No significant difference in umbilical cord blood base excess ≤ -12 mmol/L, Apgar 5 min < 7, Apgar 5 min < 4, umbilical cord blood PH 

2018 European journal of obstetrics, gynecology, and reproductive biology

9. Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes

Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03665779 Recruitment

2018 Clinical Trials

10. Contraction of the levator ani muscle during Valsalva maneuver (co-activation) is associated with a longer active second stage of labor in nulliparous women undergoing induction of labor. (PubMed)

Contraction of the levator ani muscle during Valsalva maneuver (co-activation) is associated with a longer active second stage of labor in nulliparous women undergoing induction of labor. The Valsalva maneuver is normally accompanied by relaxation of the levator ani muscle, which stretches around the presenting part, but in some women the maneuver is accompanied by levator ani muscle contraction, which is referred to as levator ani muscle coactivation. The effect of such coactivation on labor (...) outcome in women undergoing induction of labor has not been previously assessed.The aim of the study was to assess the effect of levator ani muscle coactivation on labor outcome, in particular on the duration of the second and active second stage of labor, in nulliparous women undergoing induction of labor.Transperineal ultrasound was used to measure the anteroposterior diameter of the levator hiatus, both at rest and at maximum Valsalva maneuver, in a group of nulliparous women undergoing induction

2018 American Journal of Obstetrics and Gynecology

11. A validated calculator to estimate risk of cesarean after an induction of labor with an unfavorable cervix

A validated calculator to estimate risk of cesarean after an induction of labor with an unfavorable cervix Induction of labor occurs in >20% of pregnancies, which equates to approximately 1 million women undergoing an induction in the United States annually. Regardless of how common inductions are, our ability to predict induction success is limited. Although multiple risk factors for a failed induction have been identified, risk factors alone are not enough to quantify an actual risk (...) cohort of women from the same institution who underwent an induction (n = 364) during the trial period. An external validation was performed utilizing a publicly available database (Consortium for Safe Labor) that includes information for >200,000 deliveries from 19 hospitals across the United States from 2002 through 2008. After applying the same inclusion and exclusion criteria utilized in the derivation cohort, a total of 8466 women remained for analysis. The discriminative power of each model

2018 EvidenceUpdates

12. Induction of labor using one dose vs multiple doses of misoprostol: a randomized controlled trial

Induction of labor using one dose vs multiple doses of misoprostol: a randomized controlled trial Misoprostol is a common agent that is used to ripen the cervix and induce labor, yet there is no clear evidence of the optimal number of doses needed to achieve a higher rate of vaginal delivery.Our primary objective was to compare the rate of vaginal delivery within 24 hours between a 1-dose and a multiple-dose regimen of misoprostol for the induction of labor.A randomized controlled trial (...) was conducted from March 2016 to March 2017 that compared a single dose to up to 4 doses of misoprostol. Randomization was stratified by parity. Women with a singleton pregnancy ≥37 weeks gestation with intact membranes who had been admitted for labor induction with a Bishop score ≤6 were included. Our primary outcome was the rate of vaginal delivery within 24 hours. Secondary outcomes included time to vaginal delivery, cesarean delivery rate, and maternal and neonatal morbidity. Based on a power of 80

2018 EvidenceUpdates

13. Outpatient Foley Catheter for Induction of Labor in Parous Women: A Randomized Controlled Trial

Outpatient Foley Catheter for Induction of Labor in Parous Women: A Randomized Controlled Trial To assess whether outpatient cervical ripening with a transcervical Foley catheter in parous women undergoing elective induction of labor shortens the total duration of time from admission to the labor ward until delivery.We performed an open-label randomized controlled trial at a single academic center in parous women at 39 weeks of gestation or greater with a cervix 3 cm or less dilated, or, if 2-3 (...) transcervical catheter placement and concomitant oxytocin infusion on the labor ward. Women in the outpatient group were instructed to return to the hospital the next day or sooner if labor occurred. Induction of labor was managed per institutional protocol, and once participants were admitted, oxytocin was initiated. The primary outcome was the duration of time from labor ward admission until delivery. Based on a prior study in our institution, a total of 128 women were needed for 80% power to detect a 12

2018 EvidenceUpdates

14. Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. (PubMed)

Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. The perinatal and maternal consequences of induction of labor at 39 weeks among low-risk nulliparous women are uncertain.In this multicenter trial, we randomly assigned low-risk nulliparous women who were at 38 weeks 0 days to 38 weeks 6 days of gestation to labor induction at 39 weeks 0 days to 39 weeks 4 days or to expectant management. The primary outcome was a composite of perinatal death or severe neonatal (...) complications; the principal secondary outcome was cesarean delivery.A total of 3062 women were assigned to labor induction, and 3044 were assigned to expectant management. The primary outcome occurred in 4.3% of neonates in the induction group and in 5.4% in the expectant-management group (relative risk, 0.80; 95% confidence interval [CI], 0.64 to 1.00). The frequency of cesarean delivery was significantly lower in the induction group than in the expectant-management group (18.6% vs. 22.2%; relative risk

2018 NEJM

15. Elective induction of labor at 39 weeks compared to expectant management in multiparous women: a systematic review and meta-analysis of cohort studies

Elective induction of labor at 39 weeks compared to expectant management in multiparous women: a systematic review and meta-analysis of cohort studies Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content (...) ruler software. In case data are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac

2019 PROSPERO

16. Concurrent administration of oxytocin with foley catheter versus misoprostol for induction of labor in singleton full term pregnancies

Concurrent administration of oxytocin with foley catheter versus misoprostol for induction of labor in singleton full term pregnancies Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration (...) software. In case data are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac ischemia

2019 PROSPERO

17. Stepwise Labor Induction Following Failure of Prostaglandin Vaginal Insert for Labor Induction

Stepwise Labor Induction Following Failure of Prostaglandin Vaginal Insert for Labor Induction Stepwise Labor Induction Following Failure of Prostaglandin Vaginal Insert for Labor Induction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Stepwise Labor Induction Following Failure of Prostaglandin Vaginal Insert for Labor Induction The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02684305 Recruitment Status : Unknown Verified March 2016 by Tel-Aviv Sourasky Medical Center. Recruitment status

2016 Clinical Trials

18. In labor or in limbo? The experiences of women undergoing induction of labor in hospital: Findings of a qualitative study. (PubMed)

In labor or in limbo? The experiences of women undergoing induction of labor in hospital: Findings of a qualitative study. Induction of labor currently accounts for around 25% of all births in high-resource countries, yet despite much research into medical aspects, little is known about how women experience this process. This study aimed to explore in depth the induction experience of primiparous women.A qualitative study was undertaken, using a sample of 21 first-time mothers from a maternity (...) unit in the south of England. Semi-structured interviews were conducted in women's homes between 3 and 6 weeks postnatally. Data were recorded, transcribed, and analyzed thematically.Women awaiting induction on the prenatal ward appeared to occupy a liminal state between pregnancy and labor. Differences were noted between women's and midwives' notions of what constituted "being in labor" and the ward lacked the flexibility to provide individualized care for women in early labor. Unexpected delays

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2017 Birth

19. Labor after cesarean delivery managed without induction or augmentation of labor. (PubMed)

Labor after cesarean delivery managed without induction or augmentation of labor. This study aimed to describe the perinatal outcomes of women opting for vaginal birth after cesarean delivery (VBAC) managed without induction or augmentation of labor.This was a retrospective cohort study of candidates for VBAC at a tertiary center in Japan from April 2003 to March 2012. Women with singleton gestations and one prior low-transverse cesarean delivery who intended VBAC at 36 weeks of gestation were (...) identified as candidates for VBAC and included in the study. Participants were managed without induction or augmentation of labor. Maternal characteristics and perinatal outcomes were obtained from medical records. Factors associated with successful VBAC were analyzed with a multivariable logistic regression model.Of 333 candidates for VBAC, 242 (72.7%) had vaginal birth, 49 (14.7%) had repeat cesarean delivery with spontaneous labor, and 42 (12.6%) had repeat cesarean delivery without spontaneous labor

2017 Birth

20. Identification of first stage labor arrest by electromyography in term nulliparous women after induction of labor. (PubMed)

Identification of first stage labor arrest by electromyography in term nulliparous women after induction of labor. Worldwide induction and cesarean delivery rates have increased rapidly, with consequences for subsequent pregnancies. The majority of intrapartum cesarean deliveries are performed for failure to progress, typically in nulliparous women at term. Current uterine registration techniques fail to identify inefficient contractions leading to first-stage labor arrest. An alternative (...) technique, uterine electromyography has been shown to identify inefficient contractions leading to first-stage arrest of labor in nulliparous women with spontaneous onset of labor at term. The objective of this study was to determine whether this finding can be reproduced in induction of labor.Uterine activity was measured in 141 nulliparous women with singleton term pregnancies and a fetus in cephalic position during induced labor. Electrical activity of the myometrium during contractions

2017 Acta Obstetricia et Gynecologica Scandinavica

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