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Labial Fusion

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1. Endoscopic examination of labial fusion in a postmenopausal woman: a case report (PubMed)

Endoscopic examination of labial fusion in a postmenopausal woman: a case report Labial fusion is defined as adhesions of the labia minora or majora. Labial fusion may cause urinary retention. Surgical treatment based on an accurate anatomic assessment may be needed, but the usefulness of endoscopic examination for this disease has not been reported.A 76-year-old Japanese woman undergoing chemoradiation treatment for esophageal cancer was referred to our department for evaluation of high (...) accumulation in the vagina on a positron emission tomography scan. On physical examination, her labia were noted to be extensively fused with a pinhole opening at the midline. Endoscopic examination revealed that her vagina was filled with urine and there were no abnormalities in her urethral meatus and cervix. The adhesions were separated under anesthesia and there has been no recurrence during follow-up.We present a case of a postmenopausal patient with labial fusion who underwent successful surgical

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2018 Journal of medical case reports

2. Labial Fusion

Labial Fusion Labial Fusion Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Labial Fusion Labial Fusion Aka: Labial Fusion , Labia (...) Minora Fusion II. Definition Labial Fusion Labia minora fuses in prepubescent girls, blocking the vaginal introitus III. Pathophysiology Low level irritation of the labia minora Hypoestrogenized labial tissue IV. Signs Labia minora fused, blocking the vaginal introitus Patient still able to urinate despite fusion V. Management Avoid manually separating the fused labia (painful, and typically refuses) Practice good hygiene with daily baths and frequent diaper changes Apply daily, a small amount

2019 FP Notebook

3. Early Diagnosis of Labial Fusion in Women after Allogeneic Hematopoietic Cell Transplant Enables Outpatient Treatment (PubMed)

Early Diagnosis of Labial Fusion in Women after Allogeneic Hematopoietic Cell Transplant Enables Outpatient Treatment The aim of the study was to describe the presentation and successful treatment of labial fusion in women after allogeneic hematopoietic cell transplantation (HCT).During routine posttransplant gynecologic evaluation, labial fusion was identified in 5 female patients. Clinical data were collected regarding underlying disease, transplant regimen, genital symptoms, systemic sites (...) of chronic graft-versus-host disease (cGvHD) and treatment, and follow-up.At presentation, women had a median age of 40 years (range = 35-50) and were 23-month to 8-year post-HCT. Four of the 5 patients with labial fusion had evidence of active cGvHD; 3 patients had severe sclerotic cGvHD, and 1 patient had bronchiolitis obliterans. One had rheumatoid arthritis and had recently stopped taking etanercept, but had no sites of cGvHD. One patient presented with only a pinpoint opening for passage of urine

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2017 Journal of lower genital tract disease

4. Labial fusion: A rare cause of urinary retention in reproductive age woman and review of literature (PubMed)

Labial fusion: A rare cause of urinary retention in reproductive age woman and review of literature Labial fusion usually affects prepubertal girls and postmenopausal women, it may rarely occurs in reproductive years in the absence of predisposing factors such as vulvar infections, dermatitis, trauma, female circumcision and lichen sclerosis. Should be considered in differential diagnosis in the differential diagnosis of urinary retention even if the patient doesn't have history of sexual

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2017 Turkish journal of urology

5. Acute renal failure due to complete labial fusion: A case report (PubMed)

Acute renal failure due to complete labial fusion: A case report Acute renal failure is characterized by rapidly disruption in kidney function and postrenal causes typically result from obstruction of urinary flow. Multiple etiologies were described for acute renal failure, but labial fusion in postmenopausal female is a quite rarely encountered pathology among postrenal causes. Only a few cases have been presented in postmenopausal women presenting with urinary retention. We present a case (...) with acute renal failure due to complete labial fusion in a postmenopausal woman and its treatment.Copyright © 2016. Published by Elsevier Ltd.

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2016 International journal of surgery case reports

6. Do hygienic factors affect labial fusion recurrence? A search for possible related etiologic factors. (PubMed)

Do hygienic factors affect labial fusion recurrence? A search for possible related etiologic factors. The purpose of our study was to define the factors related to recurrence of labial fusion.The data of 110 patients diagnosed with labial fusion were gathered. The data collected and queried included age and body weight of the patient, season of presentation/occurrence, frequency of diaper change, frequency of diaper dermatitis, products used for hygiene, duration of breast milk feeding (...) , infections, presence of allergy, thickness of the adhesion, mother's use of oral contraceptive drugs before pregnancy, mother's use of alcohol/drugs/cigarettes or presence of disease during pregnancy, the number of recurrences, treatment method, presence of labial fusion among maternal sisters or any relatives, and blood estrogen levels.Eighty-one patients (73.6%) with labial fusion were admitted for the first time, whereas 29 patients (26.4%) had been treated previously at least once. The adhesion

2012 Journal of Pediatric Surgery

7. Treatment of Prepubertal Labial Adhesions

of labial adhesions in prepubertal girls. Generally, for medical treatment of labial adhesions, topical estrogen is applied to the adhesion whist applying gentle lateral traction to promote separation of the labia. It is, therefore, plausible that the lateral traction applied to the adhesion site is what ultimately results in the separation of the labial fusion, while the use of estrogen improves healing after mechanical separation. This is a single site, prospective, randomized, double-blinded study (...) provided by Tazim Dowlut-McElroy, Children's Mercy Hospital Kansas City: Vulvar disease, adhesions, topical therapy Labial adhesions prepubertal girls Labial agglutination Labial fusion Additional relevant MeSH terms: Layout table for MeSH terms Tissue Adhesions Cicatrix Fibrosis Pathologic Processes Estradiol Polyestradiol phosphate Estradiol 3-benzoate Estradiol 17 beta-cypionate Estrogens Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Physiological Effects of Drugs Contraceptive

2014 Clinical Trials

8. Labial Adhesions (Diagnosis)

Updated: Dec 13, 2018 Author: Kenneth G Nepple, MD; Chief Editor: Andrea L Zuckerman, MD Share Email Print Feedback Close Sections Sections Labial Adhesions Overview Practice Essentials Labial adhesions (also referred to as labial agglutination) are a common disorder in prepubertal females. They are a fusion of labia minora in the midline, are usually asymptomatic, and typically can be treated conservatively. Labial adhesions must be differentiated from other pediatric vaginal or urethral disorders (...) . Treasure Island, FL: StatPearls; 2018. . Gaudens DA, Moh-Ello N, Fiogbe M, Bandre E, Ossoh BM, Yaokreh JB, et al. [Labial fusion in the paediatric surgery department of Yopougon University hospital (Côte d'Ivoire): 108 cases]. Sante . 2008 Jan-Mar. 18 (1):35-8. . Bacon JL, Romano ME, Quint EH. Clinical Recommendation: Labial Adhesions. J Pediatr Adolesc Gynecol . 2015 Oct. 28 (5):405-9. . Leung AK, Robson WL, Tay-Uyboco J. The incidence of labial fusion in children. J Paediatr Child Health . 1993 Jun

2014 eMedicine Pediatrics

9. Labial Adhesions (Overview)

: Dec 13, 2018 Author: Kenneth G Nepple, MD; Chief Editor: Andrea L Zuckerman, MD Share Email Print Feedback Close Sections Sections Labial Adhesions Overview Practice Essentials Labial adhesions (also referred to as labial agglutination) are a common disorder in prepubertal females. They are a fusion of labia minora in the midline, are usually asymptomatic, and typically can be treated conservatively. Labial adhesions must be differentiated from other pediatric vaginal or urethral disorders (eg (...) : StatPearls; 2018. . Gaudens DA, Moh-Ello N, Fiogbe M, Bandre E, Ossoh BM, Yaokreh JB, et al. [Labial fusion in the paediatric surgery department of Yopougon University hospital (Côte d'Ivoire): 108 cases]. Sante . 2008 Jan-Mar. 18 (1):35-8. . Bacon JL, Romano ME, Quint EH. Clinical Recommendation: Labial Adhesions. J Pediatr Adolesc Gynecol . 2015 Oct. 28 (5):405-9. . Leung AK, Robson WL, Tay-Uyboco J. The incidence of labial fusion in children. J Paediatr Child Health . 1993 Jun. 29 (3):235-6. . Cağlar

2014 eMedicine Pediatrics

10. Labial Adhesions (Treatment)

of the pediatrician, a pediatric gynecologist, or a pediatric urologist. Previous References Gonzalez D, Mendez MD. Labial Adhesions . Treasure Island, FL: StatPearls; 2018. . Gaudens DA, Moh-Ello N, Fiogbe M, Bandre E, Ossoh BM, Yaokreh JB, et al. [Labial fusion in the paediatric surgery department of Yopougon University hospital (Côte d'Ivoire): 108 cases]. Sante . 2008 Jan-Mar. 18 (1):35-8. . Bacon JL, Romano ME, Quint EH. Clinical Recommendation: Labial Adhesions. J Pediatr Adolesc Gynecol . 2015 Oct. 28 (5 (...) ):405-9. . Leung AK, Robson WL, Tay-Uyboco J. The incidence of labial fusion in children. J Paediatr Child Health . 1993 Jun. 29 (3):235-6. . Cağlar MK. Serum estradiol levels in infants with and without labial adhesions: the role of estrogen in the etiology and treatment. Pediatr Dermatol . 2007 Jul-Aug. 24 (4):373-5. . McCann J, Voris J, Simon M. Labial adhesions and posterior fourchette injuries in childhood sexual abuse. Am J Dis Child . 1988 Jun. 142 (6):659-63. . Muram D. Labial adhesions

2014 eMedicine Pediatrics

11. Labial Adhesions (Follow-up)

of the pediatrician, a pediatric gynecologist, or a pediatric urologist. Previous References Gonzalez D, Mendez MD. Labial Adhesions . Treasure Island, FL: StatPearls; 2018. . Gaudens DA, Moh-Ello N, Fiogbe M, Bandre E, Ossoh BM, Yaokreh JB, et al. [Labial fusion in the paediatric surgery department of Yopougon University hospital (Côte d'Ivoire): 108 cases]. Sante . 2008 Jan-Mar. 18 (1):35-8. . Bacon JL, Romano ME, Quint EH. Clinical Recommendation: Labial Adhesions. J Pediatr Adolesc Gynecol . 2015 Oct. 28 (5 (...) ):405-9. . Leung AK, Robson WL, Tay-Uyboco J. The incidence of labial fusion in children. J Paediatr Child Health . 1993 Jun. 29 (3):235-6. . Cağlar MK. Serum estradiol levels in infants with and without labial adhesions: the role of estrogen in the etiology and treatment. Pediatr Dermatol . 2007 Jul-Aug. 24 (4):373-5. . McCann J, Voris J, Simon M. Labial adhesions and posterior fourchette injuries in childhood sexual abuse. Am J Dis Child . 1988 Jun. 142 (6):659-63. . Muram D. Labial adhesions

2014 eMedicine Pediatrics

12. Management of Acute Obstructive Uterovaginal Anomalies

with amenorrhea, dysmenorrhea, pelvic pain, recurrent vaginal discharge, or infertility. The evaluation of a patient with a suspected obstructive reproductive anomaly should include a detailed medical history, physical examination, and imaging. The genital examination is critical to differentiate a patient with an imperforate hymen from a patient with labial adhesions, urogenital sinus, transverse vaginal septum, or distal vaginal atresia. Pelvic ultrasonography is the initial imaging method recommended (...) anomalies. Obstetrician– gynecologists should be aware of obstructive conditions that result from a failure of the müllerian ducts to fuse. Incomplete vertical fusion of the caudal müllerian duct with the sinovaginal bulbs leads to cervical atresia, transverse vaginal septa, or distal vaginal atresia. Incomplete resorption ofuterineorvaginalsepta leadsto rudimentary and obstructed uterine horns or obstructive hemivagina and ipsilateral renal anomaly (also referred to as OHVIRA or Herlyn-Werner

2019 American College of Obstetricians and Gynecologists

13. Diagnosis and Management of Hymenal Variants

.) VOL. 133, NO. 6, JUNE 2019 Committee Opinion Hymenal Variants e3753. Joki-ErkkilaMM,HeinonenPK.Presentingandlong-term clinical implications and fecundity in females with ob- structing vaginal malformations. J Pediatr Adolesc Gyne- col 2003;16:307–12. 4. Schober J, Dulabon L, Martin-Alguacil N, Kow L, Pfaff D. Significance of topical estrogens to labial fusion and vag- inal introital integrity. J Pediatr Adolesc Gynecol 2006;19: 337–9. 5. Ossman AME, El-Masry YI, El-Namoury MM, Sarsik SM (...) with expertise in the management of these conditions. RecommendationsandConclusions The American College of Obstetricians and Gynecologists makes the following recommendations and conclusions: c The presentation and management of clinically significant hymenal variations differs depending on the age of the patient at onset of symptoms and associated complications. c On evaluation, the goal is to differentiate an imperforatehymenfromotherobstructinganatomic etiologies, such as labial adhesions, urogenital

2019 American College of Obstetricians and Gynecologists

15. British Association of Dermatologists' guidelines for the management of lichen sclerosus

of key future research recommendations (FRRs) FRR1 What is the role of topical calcineurin inhibitors in treating people with LS? FRR2 What is the role of topical steroids in preventing malig- nancy in genital LS in female patients? FRR3 What is the course of LS after puberty in female patients? FRR4 What is the optimal surgical management of female patients with fusion over the clitoris? FRR5 Would acitretin in combination with a topical steroid be more effective than monotherapy in treating people (...) . The role of HPV in penile LS-associated SCC has also been debated. Some studies using polymerase chain reaction have documented a negligible frequency of HPV in LS, 90,91 but other studies have suggested a frequency of up to 33%. 92,93 An addi- tional feature that has been linked with penile LS-associated SCC is the occurrence of a prominent lichenoid in?ltrate on long- standing, chronic LS, suggesting disease reactivation. 94 5.6.2 Scarring Introital narrowing Anterior and/or posterior fusion

2018 British Association of Dermatologists

16. Gynecologic Issues in Children and Adolescent Cancer Patients and Survivors

, or compromised fertility (6). Stem Cell Transplant Graft-versus-host disease is a manifestation of hemato- poietic allogenic stem cell transplantation with a high prevalence of 11–48% (13). Vaginal symptoms include pain, itching, burning, dyspareunia, labial fusion, vaginal synechiae, and stenosis. Early identification is the key to preventing long-term sequelae such as vaginal stenosis andhematocolpos;however,thereisfrequentlyadelayto diagnosis. A careful examination by a gynecologist is encouraged

2018 American College of Obstetricians and Gynecologists

18. BSR guideline Management of Adults with Primary Sjögren's Syndrome

dryness (Schirmer’s test ⩽5 mm in 5 min or van Bijsterveld score ⩾4), objective oral dryness (unstimulated salivary flow rate ⩽0.1 ml/min or positive salivary scintigraphy and sialography), positive anti-Ro/La antibodies, labial gland focus score ⩾1 including at least one of the last two objective features. The 2016 ACR–EULAR classification criteria are based on the weighted sum of five items and require a total score ⩾4 to meet the criteria for diagnosis where the presence of anti-Ro antibodies (...) , depend on the classification criteria used, referral bias and access to labial gland biopsy. Need for guideline pSS typically presents in women in their fifth or sixth decade, although up to 10% of cases occur in men and it is also seen in younger people. Studies using the AECG criteria have estimated the prevalence in women in the UK at 0.1–0.4% [ ]. Patients present to primary care physicians, general physicians, ophthalmologists and dental practitioners many of whom lack specialist knowledge

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2017 British Society for Rheumatology

19. Salivary Gland Cancer Treatment (Adult) (PDQ®): Health Professional Version

of this grading system placed more emphasis on features of tumor invasion.[ ] Nonetheless, though tumor grade may be useful, stage appears to be a better indicator of prognosis.[ , ] Cytogenetically, mucoepidermoid carcinoma is characterized by a t(11;19)(q14–21;p12–13) translocation, which is occasionally the sole cytogenetic alteration.[ - ] This translocation creates a novel fusion product, MECT1-MAML2, which disrupts a Notch signaling pathway.[ ] Notch signaling plays a key role in the normal development (...) patients treated at the National Cancer Institute of Milan. Ann Surg Oncol 9 (7): 688-95, 2002. [ ] Neville BW, Damm DD, Weir JC, et al.: Labial salivary gland tumors. Cancer 61 (10): 2113-6, 1988. [ ] Auclair PL, Goode RK, Ellis GL: Mucoepidermoid carcinoma of intraoral salivary glands. Evaluation and application of grading criteria in 143 cases. Cancer 69 (8): 2021-30, 1992. [ ] Brandwein MS, Ivanov K, Wallace DI, et al.: Mucoepidermoid carcinoma: a clinicopathologic study of 80 patients with special

2018 PDQ - NCI's Comprehensive Cancer Database

20. Management Considerations for Pediatric Oral Surgery and Oral Pathology

in the median palatal raphe area 48-52 as a result of trapped epithelial remnants along the line of fusion of the palatal halves. 44,46 Dental lamina cysts, found on the crests of the dental ridges, most commonly are seen bi- laterally in the region of the first primary molars. 50 They result from remnants of the dental lamina. Bohn’s nodules are rem- nants of salivary gland epithelium and usually are found on the buccal and lingual aspects of the ridge, away from the midline. 48,49,51 Epstein’s pearls (...) , the etiology of this condition remains unknown, there appears to be a higher predilection in males towards anomalies of frenum attachments, whether it is ankyloglossia or hypertrophic/restrictive maxillary labial frenum. 68,74,76 Ankyloglossia/restrictive mandibular lingual frenum Ankyloglossia is a developmental anomaly of the tongue characterized by a short, thick lingual frenum resulting in limitation of tongue movement (partial ankyloglossia) or by the tongue appearing to be fused to the floor

2015 American Academy of Pediatric Dentistry

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