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Knee Exam

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13241. A Four-Week Study Comparing Acetaminophen Extended Release and Rofecoxib in the Treatment of Osteoarthritis of the Knee

A Four-Week Study Comparing Acetaminophen Extended Release and Rofecoxib in the Treatment of Osteoarthritis of the Knee A Four-Week Study Comparing Acetaminophen Extended Release and Rofecoxib in the Treatment of Osteoarthritis of the Knee - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. A Four-Week Study Comparing Acetaminophen Extended Release and Rofecoxib in the Treatment of Osteoarthritis of the Knee The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00568295 Recruitment Status : Completed First

2007 Clinical Trials

13242. A Placebo-Controlled Study of Collagen Hydrolysate in Subjects With Knee Osteoarthritis (OA)

on the affirmative response to the question "During the past 6 months, have you had any pain in the knee more than half the days of the month ?" WOMAC pain subscale score ≥ 1 tibiofemoral or patellofemoral osteoarthritis on anteroposterior weight-bearing semi-flexed or lateral knee radiographs with at least one osteophyte and no significant joint-space-narrowing clinical examination confirming knee pain or discomfort referable to the knee joint prepared to refrain from use of glucosamine, chondroitin, sAME (...) A Placebo-Controlled Study of Collagen Hydrolysate in Subjects With Knee Osteoarthritis (OA) A Placebo-Controlled Study of Collagen Hydrolysate in Subjects With Knee Osteoarthritis (OA) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2007 Clinical Trials

13243. Measuring Gait And Self-Reported Pain In Patients With Osteoarthritis Of The Knee Using Placebo/Oxycodone/Celecoxib.

will be allowed into the study. The index knee should be defined as the more painful knee Predominantly patellofemoral knee osteoarthritis in the index knee as assessed by clinical examination Subject who are unable to discontinue all formulations of prior analgesics other than acetaminophen during the Washout Period of the study, or who are anticipated to be unable to discontinue rescue medication for 24 hours prior to the respective visits. (Low dose aspirin may be taken for cardiac prophylaxis Excessive (...) Measuring Gait And Self-Reported Pain In Patients With Osteoarthritis Of The Knee Using Placebo/Oxycodone/Celecoxib. Measuring Gait And Self-Reported Pain In Patients With Osteoarthritis Of The Knee Using Placebo/Oxycodone/Celecoxib. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2007 Clinical Trials

13244. Proof-of Concept Study of Topical 3%-Diclofenac-Nano-Emulsion Cream for Knee OA Pain

Proof-of Concept Study of Topical 3%-Diclofenac-Nano-Emulsion Cream for Knee OA Pain Proof-of Concept Study of Topical 3%-Diclofenac-Nano-Emulsion Cream for Knee OA Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Proof-of Concept Study of Topical 3%-Diclofenac-Nano-Emulsion Cream for Knee OA Pain The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00484120 Recruitment Status : Completed First Posted : June 8, 2007 Last Update Posted : August 2, 2011 Sponsor: Pharmos Information provided by: Pharmos

2007 Clinical Trials

13245. Pre-operative Rehabilitation Exercise Program for Total Knee Arthroplasty

/treatment Phase Osteoarthritis Rheumatoid Arthritis Behavioral: Exercise Not Applicable Detailed Description: Patients with lower levels of function prior to total knee arthroplasty (TKA) attain lower functional endpoints after surgery. Therapeutic exercise improves function in patients with arthritis of the knee, yet little evidence has examined the impact of pre-operative exercise for TKA. Single blinded randomized clinical trial comparing a pre-operative home exercise program to pre-operative usual (...) Pre-operative Rehabilitation Exercise Program for Total Knee Arthroplasty Pre-operative Rehabilitation Exercise Program for Total Knee Arthroplasty - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pre

2007 Clinical Trials

13246. The efficacy and tolerability of glucosamine sulfate in the treatment of knee osteoarthritis: A randomized, double-blind, placebo-controlled trial. Full Text available with Trip Pro

The efficacy and tolerability of glucosamine sulfate in the treatment of knee osteoarthritis: A randomized, double-blind, placebo-controlled trial. Osteoarthritis (OA) is the most common form of arthritis and is often associated with disability and impaired quality of life.The aim of the study was to assess the efficacy and tolerability of glucosamine sulfate (GS) in the treatment of knee OA.Consecutive outpatients affected by primary monolateral or bilateral knee OA were enrolled (...) in this double-blind, double-dummy, prospective, randomized, placebo-controlled trial. One group received GS 1500 mg QD for 12 weeks, and the other group received placebo QD for 12 weeks. The treatment period was followed by a 12-week treatment-free observation phase. Each patient was examined at baseline and at weeks 4, 8, 12, 16, 20, and 24. The primary efficacy criteria were pain at rest and during movement, assessed on a visual analog scale (VAS) of 0 to 100 mm. The secondary criteria included

2009 Current therapeutic research, clinical and experimental Controlled trial quality: predicted high

13247. Evaluation of the effectiveness and tolerability of controlled-release diclofenac-potassium versus immediate-release diclofenac-potassium in the treatment of knee osteoarthritis. Full Text available with Trip Pro

Evaluation of the effectiveness and tolerability of controlled-release diclofenac-potassium versus immediate-release diclofenac-potassium in the treatment of knee osteoarthritis. Abstract.A controlled-release (CR) form of diclofenac-potassium has been developed, which delivers 100 mg over the course of 24 hours. This formulation is administered QD and provides steady plasmatic levels of the drug.The aim of this study was to compare the effectiveness and tolerability of CR diclofenac-potassium (...) versus the immediate-release (IR) formulation, when used for treatment of pain in patients with knee osteoarthritis.This prospective, randomized, double-blind, comparative, multi-center, parallel-group study was conducted in male and female patients who had been previously diagnosed with knee osteoarthritis. Inclusion criteria included knee joint pain and ≥3 of the following: age >50 years, morning rigidity lasting <30 minutes, crackling in the joint, pain with applied pressure to the bones, bone

2007 Current therapeutic research, clinical and experimental Controlled trial quality: uncertain

13248. Does transcutaneous electrical nerve stimulation improve the physical performance of people with knee osteoarthritis? (Abstract)

Does transcutaneous electrical nerve stimulation improve the physical performance of people with knee osteoarthritis? : According to a recent metaanalysis study, there is strong evidence to support the view that transcutaneous electrical nerve stimulation (TENS) is an effective treatment for managing osteoarthritis (OA) knee pain. However, there is limited evidence showing its effectiveness in improving physical function. This study examined whether TENS alone can improve physical function (...) in terms of range of knee motion and the Timed-Up-and-Go Test.: Subjects were randomly allocated into 2 groups receiving TENS at 100 Hz or a placebo TENS. Outcome measures included: 1) visual analog scale for measuring the intensity of the present pain, 2) Timed-Up-and-Go Test, and 3) range of knee motion (ROM). Repeated-measures analysis of variance and Pearson correlation were used for data analyses.: By day 10, TENS produced a significantly greater increase in maximum knee ROM than the placebo group

2006 Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases Controlled trial quality: uncertain

13249. Prehabilitation before knee arthroplasty increases postsurgical function: a case study. (Abstract)

Prehabilitation before knee arthroplasty increases postsurgical function: a case study. Conditioning the body to undergo physical stress such as joint arthroplasty has been termed prehabilitation. This case study examined the effect of a 4-week prehabilitation intervention on functional outcomes after total knee arthroplasty (TKA). Two female subjects completed baseline strength and functional assessments before TKA. Subjects were randomized to either a 4-week prehabilitation intervention (ES (...) on functional task performance and knee proprioception before surgery. After surgery, the ES continued to exhibit higher levels of functioning and less pain compared with the CS. Prehabilitation before TKA may contribute to improved recovery after surgery.

2007 Journal of strength and conditioning research / National Strength & Conditioning Association

13250. A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery

or physical exam (positive lachmann and pivot shift tests) resulting in giving way episodes (acute or chronic) unresponsive to non-operative management and therefore requiring primary ACL reconstruction. - Arthroscopic: Concomitant meniscal resection. Exclusion Criteria: - Clinical: Previous surgery on either knee (not including a diagnostic arthroscopy arthroscopy or simple partial meniscectomy,) Concomitant lower extremity fracture, Ipsilateral collateral ligament injury within past 3 months, Time from (...) A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2006 Clinical Trials

13251. Effects of Shoes Insoles on Symptoms and Disease Progression in Knee Osteoarthritis

will be confirmed by radiographic and clinical examination People with medial tibiofemoral joint OA fulfilling American College of Rheumatology classification criteria and reporting average knee pain on walking >3 on an 11-point scale varus knee malalignment on standing anteroposterior lower limb x-ray. Exclusion Criteria: advanced radiographic knee OA (Kellgren and Lawrence stage 4 knee surgery or intra-articular corticosteroid injection within 6 months current or past (within 4 weeks) oral corticosteroid use (...) Effects of Shoes Insoles on Symptoms and Disease Progression in Knee Osteoarthritis Effects of Shoes Insoles on Symptoms and Disease Progression in Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2006 Clinical Trials

13252. Osteopuncture for Osteoarthritis-Associated Knee Pain & Disability

for Study: 65 Years and older (Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Radiographic evidence of knee OA on a standing AP X-ray Bilateral knee pain for at least 3 months with pain of at least moderate intensity every day or almost every day Exclusion Criteria: Non-ambulatory, or severely impaired mobility (i.e., require the use of a walker) Folstein Mini-Mental State Examination score of less than 24 Severe visual or hearing impairment Knee (...) Osteopuncture for Osteoarthritis-Associated Knee Pain & Disability Osteopuncture for Osteoarthritis-Associated Knee Pain & Disability - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Osteopuncture

2006 Clinical Trials

13253. Using Ultrasonography to Predict Clinical Response to Intraarticular Corticosteroids in Knee Osteoarthritis

is that local corticosteroids do no act to relieve pain by reducing synovitis. These putative mechanisms have yet to be elucidated. Perhaps a more plausible explanation is that current methods of assessing local inflammation in OA are inadequate. Recent studies involving ultrasonography (US) demonstrate that US is a valid and reproducible tool for the detection of synovitis in the knee. It has been shown to be more sensitive than clinical examination and is relatively inexpensive and noninvasive. Study (...) Using Ultrasonography to Predict Clinical Response to Intraarticular Corticosteroids in Knee Osteoarthritis Using Ultrasonography to Predict Clinical Response to Intraarticular Corticosteroids in Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2006 Clinical Trials

13254. A Study of the Efficacy and Safety of EUFLEXXAâ„¢ for Treatment of Painful Osteoarthritis of the Knee

a walk of 50 feet in length between the baseline (week 0) and week 26 scores. Scores are measured on a visual analog scale of 100 millimeters; a score of 0 millimeters meaning no pain was observed; a score of 100 millimeters meaning extreme pain was observed. Shifts From Extension Study Baseline (Week 26) in Range of Motion Findings at Week 52 [ Time Frame: weeks 26 and 52 ] Number of participants in various categories of target knee joint examination findings from baseline (week 26 pre-injection (...) ) to week 52. Range of motion indicates the flexibility of the knee, and is measured by the number of degrees between when the knee is hyper-extended and when the knee is flexed. Shifts From Extension Study Baseline (Week 26) in Ratings of Knee Tenderness at Week 52 [ Time Frame: weeks 26 and 52 ] Number of participants in various categories of target knee joint examination findings from baseline (week 26 pre-injection) to week 52. Tenderness of the knee was subjectively rated by participants as none

2006 Clinical Trials

13255. Gait Evaluation of Experienced Below Knee Amputees

Gait Evaluation of Experienced Below Knee Amputees Gait Evaluation of Experienced Below Knee Amputees - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Gait Evaluation of Experienced Below Knee Amputees (...) with an experience of over 3 months of prosthesis use at home, without any known difficulty using the prosthesis and without stump pathology, using no assistive devices, will be examined in a 3 D computerized gait laboratory. Kinematic and kinetic parameters of gait will be obtained. Condition or disease Amputations, Traumatic Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 9 participants Time Perspective: Prospective Official Title: Gait Evaluation

2006 Clinical Trials

13256. Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery

Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery (TREK) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00331838 Recruitment Status : Completed First Posted : May 31, 2006 Last Update Posted : January 15

2006 Clinical Trials

13257. Ketoprofen in Transfersome Compared to Oral Celecoxib and Placebo for Pain Associated With Osteoarthritis of the Knee

within 3 months prior to screening Signs of any clinically important inflammation of the index knee including redness, warmth and or a large bulging effusion with the loss of normal contour Crystalline-induced synovitis in the index knee History, physical examination or radiographic suggestive of acute inflammatory arthritis, rheumatoid arthritis, psoriatic arthritis, septic arthritis, gout, pseudogout, fibromyalgia, lupus erythematosus, or other types of inflammatory arthritis of the index knee (...) Ketoprofen in Transfersome Compared to Oral Celecoxib and Placebo for Pain Associated With Osteoarthritis of the Knee Ketoprofen in Transfersome Compared to Oral Celecoxib and Placebo for Pain Associated With Osteoarthritis of the Knee - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2006 Clinical Trials

13258. Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis

Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00352625 Recruitment Status : Completed First Posted : July

2006 Clinical Trials

13259. Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis

medical care for painful knee osteoarthritis alignment based on AP standing radiographs of neutral to 10º of valgus no prior surgery on the ipsilateral knee no history of major trauma to either knee or either hip no history of congenital hip dysplasia No history of inflammatory synovitis or crystalline arthropathy No history of systemic rheumatic disease cruciate and collateral ligament stability, defined by clinical examination meniscus intact (MRI grade II degenerative signal acceptable) Noyes (...) effusion with a ballotable patella on baseline clinical exam Inability to safely perform MR imaging Active systemic infection Active malignancy (except non-melanomatous skin cancer) Allergies to HA or chicken products Clinical symptoms of an acute meniscal tear (locking, new acute mechanical symptoms etc…) A recent injury to the knee Radiographic evidence of Grade III or IV Kellgren and Lawrence OA Chondrocalcinosis on radiographs Unwilling to discontinue or avoid glucosamine chondroitin sulfate

2006 Clinical Trials

13260. Educational Intervention for Knee Pain

dichotomized for analysis. Responses "definitely" and "probably willing" were combined and compared to "unsure", "probably not willing", and "definitely not willing" combined. Secondary Outcome Measures : To Examine and Compare the Effectiveness of the Proposed Intervention Strategies to Increase AA Patient Likelihood of Receiving Knee Replacement Within 12 Months of the Intervention. [ Time Frame: 12 months ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing (...) Educational Intervention for Knee Pain Educational Intervention for Knee Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Educational Intervention for Knee Pain The safety and scientific validity

2006 Clinical Trials

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