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Knee Exam

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1061. Smoking and osteoarthritis: is there an association? The Clearwater Osteoarthritis Study. (PubMed)

Smoking and osteoarthritis: is there an association? The Clearwater Osteoarthritis Study. To evaluate the association between cigarette smoking and the subsequent development of osteoarthritis (OA) at four separate sites: knee, hand, foot and cervical spine.This cohort study examined 2505 men and women aged 40 years and older participating in the longitudinal Clearwater Osteoarthritis Study (1988-current). Biennial physical exams, including serial radiographs, as well as historical information (...) , were collected. The Lawrence and Kellgren ordinal scale was used to determine radiological evidence of the study outcome, OA. Self-reported history of smoking behavior was used to determine the study exposure. Smoking was classified using four approaches: (1) ever/never, (2) former/never, (3) current/never, and (4) dose.Among the individuals at study entry, radiologically confirmed incident OA was detected during the follow-up period at four sites: knee (32%), hand (49%), foot (28%), and cervical

2003 Osteoarthritis and Cartilage

1062. Waiting times at CHUM 1: diagnostic imaging, hip and knee replacements,cardiac surgery, cancer care and sight restoration

general (DG) which manifested a growing interest in the real wait times experienced by patients who required diagnostic procedures or therapeutic acts in the 5 priority areas determined by the Federal and Quebecois governments (diagnostic imaging, hip and knee replacements, cancer care, sight restoration and cardiac surgery). Authors' conclusions We reached our goal to learn the real wait times experiences by patients waiting for care or diagnostic exams at the CHUM. Thus, we noted that emergency (...) and urgent cases in the categories considered in this report have access to care very rapidly within required delays. However, access to care services is occasionally compromised for elective cases. Hereafter, we summarize our principal conclusions : Long wait times exist for hip and knee replacements (arthroplasties) and knee arthroscopy Waiting for diagnostic examinations at the departments of nuclear medicine and radiology is also long Cardiac exams are generally delivered on time according

2007 Health Technology Assessment (HTA) Database.

1063. NIH Consensus Development Conference on Total Knee Replacement

NIH Consensus Development Conference on Total Knee Replacement NIH Consensus Statement on Total Knee Replacement NIH Consensus and State-of-the-Science Statements Volume 20, Number 1 December 8–10, 2003 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of the Director About the NIH Consensus Development Program NIH Consensus Development and State-of-the-Science Conferences are convened to evaluate the available scientific evidence on a given biomedical or public (...) bibliographic reference to this consensus statement, it is recommended that the following format be used, with or without source abbreviations, but without authorship attribution: NIH Consensus Statement on Total Knee Replacement. NIH Consens State Sci Statements. 2003 Dec 8–10; 20(1) 1–32. Publications Ordering Information NIH Consensus Statements, State-of-the-Science Statements, and Technol­ ogy Assessment Statements and related materials are available by writing to the NIH Consensus Development Program

2003 NIH Consensus Statements

1064. Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis

, with Pittsburgh Sleep Quality Index > 5 [36]. Exclusion Criteria: Patients with diagnosis of obstructive sleep apnea (OSA). OR, Patients with dense hemiplegia secondary to cerebrovascular accident. OR, NYHA Class III - patients with heart failure condition limited by minimal activity. OR, Severe COPD with shortness of breath at minimal exertion. OR, Peripheral vascular disease with severe claudication. OR, Dementia with Mini Mental Status Exam score of 20 or less. OR, Patients who received knee intra (...) Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Acupuncture for Pain

2008 Clinical Trials

1065. Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis

effusion with a ballotable patella on baseline clinical exam Inability to safely perform MR imaging Active systemic infection Active malignancy (except non-melanomatous skin cancer) Allergies to HA or chicken products Clinical symptoms of an acute meniscal tear (locking, new acute mechanical symptoms etc…) A recent injury to the knee Radiographic evidence of Grade III or IV Kellgren and Lawrence OA Chondrocalcinosis on radiographs Unwilling to discontinue or avoid glucosamine chondroitin sulfate (...) Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2006 Clinical Trials

1066. Vitamin D to Slow Progression of Knee Osteoarthritis

at 2,000 International Units (IU) a day or placebo. Each participant will be in the study for about 2 years. During that time, there will be 9 scheduled study visits (screening, Months 0, 2, 4, 8, 12, 16, 20, and 24) and interim safety visits as needed. Measurements of vital signs, a knee exam, blood and urine collection, pill counts, and completion of questionnaires will occur at all visits. Participants' physical function will be assessed at study entry and Months 0, 12, and 24. MRI, bone density (...) Vitamin D to Slow Progression of Knee Osteoarthritis Vitamin D to Slow Progression of Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Vitamin D to Slow Progression of Knee Osteoarthritis

2006 Clinical Trials

1067. Intensive Diet and Exercise for Improving Knee Osteoarthritis in Obese and Overweight Older Adults

of significant dietary restriction, exercise, and a combination of both in reducing knee inflammation and compressive forces in obese and overweight adults with knee OA. The study will also examine how diet and exercise affect everyday function and pain levels, as well as the extent of weight loss necessary for slowing OA disease progression. This study will last 18 months. Four, 2-hour screening visits will include various questionnaires, physical exams, physical performance tests, x-rays, and blood (...) Intensive Diet and Exercise for Improving Knee Osteoarthritis in Obese and Overweight Older Adults Intensive Diet and Exercise for Improving Knee Osteoarthritis in Obese and Overweight Older Adults - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2006 Clinical Trials

1068. Review for the generalist: evaluation of anterior knee pain. (Full text)

Review for the generalist: evaluation of anterior knee pain. Anterior knee pain is common in children and adolescents. Evaluation and management is challenging and requires a thorough history and physical exam, and understanding of the pediatric skeleton. This article will review common causes of chronic anterior knee pain in the pediatric population with a focus on patellofemoral pain.

2007 Pediatric Rheumatology

1069. A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery

or physical exam (positive lachmann and pivot shift tests) resulting in giving way episodes (acute or chronic) unresponsive to non-operative management and therefore requiring primary ACL reconstruction. - Arthroscopic: Concomitant meniscal resection. Exclusion Criteria: - Clinical: Previous surgery on either knee (not including a diagnostic arthroscopy arthroscopy or simple partial meniscectomy,) Concomitant lower extremity fracture, Ipsilateral collateral ligament injury within past 3 months, Time from (...) A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2006 Clinical Trials

1070. Temporary Prosthesis in Traumatic Below-knee Amputation

Temporary Prosthesis in Traumatic Below-knee Amputation Temporary Prosthesis in Traumatic Below-knee Amputation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Temporary Prosthesis in Traumatic Below-knee (...) exam). Gait analysis. Variables: Preinjury morbidity and socioeconomical status. Injury severity (RTS, ISS). Prehospital and hospital analgesia. Postoperative infection. Amputation stump quality (clinical rating). Sampling: Given test power =0.8, significance level =0.05, sequential analysis of results, an estimate of 15 patients will be included in each study group. The sample may be modified due to sequential analysis (see below). Intervention: A mobile rural workshop takes molds and adapt

2005 Clinical Trials

1071. Flavocoxid, A Plant-Derived Therapy, for the Treatment of Knee Osteoarthritis

Flavocoxid, A Plant-Derived Therapy, for the Treatment of Knee Osteoarthritis Flavocoxid, A Plant-Derived Therapy, for the Treatment of Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Flavocoxid, A Plant-Derived Therapy, for the Treatment of Knee Osteoarthritis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00294125 Recruitment Status : Completed First Posted : February 20, 2006 Last Update Posted : April 22, 2013 Sponsor: University of Alabama at Birmingham Collaborators: National

2006 Clinical Trials

1072. Defining the Best Approach to Block the Pain After Knee Surgery

range of bending [ Time Frame: measured before surgery, and at days 7, 60, 90 ] thigh circumference 20 cm above the knee [ Time Frame: measured before surgery and at days 7, 60, 90 ] neurological exam of femorocutaneous, femoral and obturator nerves [ Time Frame: evaluated once spinal anesthesia has worn off, post-surgery, before anesthesia ] level of activity; measured using questionnaire [ Time Frame: at 7-10 days and at 2 and 3 months ] need for rescue analgesia [ Time Frame: in recovery room (...) Defining the Best Approach to Block the Pain After Knee Surgery Defining the Best Approach to Block the Pain After Knee Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Defining the Best Approach

2006 Clinical Trials

1073. Tanezumab in Osteoarthritis of the Knee

Tanezumab in Osteoarthritis of the Knee Tanezumab in Osteoarthritis of the Knee - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Tanezumab in Osteoarthritis of the Knee The safety and scientific validity (...) of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00733902 Recruitment Status : Completed First Posted : August 13, 2008 Last Update Posted : January 7, 2011 Sponsor: Pfizer Information provided by: Pfizer Study Details Study Description Go to Brief Summary: Test the efficacy and safety of 3 doses in Osteoarthritis of the knee in patients

2008 Clinical Trials

1074. Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery

Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00633438 Recruitment Status : Completed First Posted : March 12, 2008 Last Update

2008 Clinical Trials

1075. Knee Articular Cartilage Debridement in Conjunction With Partial Meniscectomy

or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 60 Years (Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria:Screening Age between 18 and 60 years BMI <35 Meniscal tear (medial or lateral) diagnosed by H+P exam and/or imaging in the index knee (...) No severe joint space narrowing (IKDC Classification) seen on weight-bearing AP X-ray in the index knee No avascular necrosis in the index knee as evidenced by preop MRI obtained within 6 months prior to randomization No Varus (>10 degrees) or Valgus (>15 degrees)knee deformities as seen by AP X-ray in the index knee Minimal or no abnormality of contralateral knee as shown by clinical exam and/or imaging Candidate for unilateral arthroscopic treatment of the knee Visual Analog Scale (VAS) pain score

2008 Clinical Trials

1076. Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip

: Weeks 2, 4, 8, 12, 24,32, 40, 48 and 56 ] Time to discontinuation [ Time Frame: All weeks ] Radiographic assessment of index joint (knee or hip) [ Time Frame: Screening period and Week 56 ] Safety (laboratories for chemistry, hematology urinalysis, ECGs, physical exams, vital signs, neurologic exams, serum anti-drug antibody assessments [ Time Frame: All weeks ] Pregnancy tests (where applicable) [ Time Frame: Weeks 8, 16, 24, 32, 40, 48 and 56 ] Work Productivity and Activity Impairment (...) Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer

2008 Clinical Trials

1077. Diagnosis of Infected Total Knee: Findings of a Multicenter Database. (Full text)

Diagnosis of Infected Total Knee: Findings of a Multicenter Database. Although total knee arthroplasty (TKA) is an effective and successful procedure, the outcome is occasionally compromised by complications including periprosthetic joint infection (PJI). Accurate and early diagnosis is the first step in effectively managing patients with PJI. At the present time, diagnosis remains dependent on clinical judgment and reliance on standard clinical tests including serologic tests, analysis (...) the current status of diagnosis of the infected TKA utilizing commonly available tests. Intraoperative cultures should not be used as a gold standard for PJI owing to high percentages of false-negative and false-positive cases. When combined with clinical judgment, total white cell count and percentage of neutrophils in the synovial fluid more accurately reflects PJI and when combined with hematologic exams safely excludes or confirms infection.Level II, prognostic study. See Guidelines for Authors

2008 Clinical Orthopaedics and Related Research

1078. A new non-invasive method to assess synovitis severity in relation to symptoms and cartilage volume loss in knee osteoarthritis patients using MRI. (Full text)

, using a 1.5T and a knee coil. For the synovial membrane, the MRI exam included two axial sequences: a T2-weighted (synovial fluid) and a gradient echo (GRE) (synovial membrane). Synovial membrane thickness was measured on four regions of interest (ROI): medial and lateral recesses, and medial and lateral suprapatellar bursa, with each graded/scored from 0 to 3, for a maximum of 12. A validation study was performed on a cohort of 27 knee OA patients having MRI at baseline. A subset of 14 patients had (...) A new non-invasive method to assess synovitis severity in relation to symptoms and cartilage volume loss in knee osteoarthritis patients using MRI. Synovitis in knee osteoarthritis (OA) patients is a significant risk factor for disease progression. This study aimed at developing a magnetic resonance imaging (MRI) scoring system allowing reliable and sensitive assessment of synovitis severity in knee OA patients without the use of a contrast agent.Imaging was performed without contrast agent

2008 Osteoarthritis and Cartilage

1079. Flexion and extension gap balancing in revision total knee arthroplasty. (Full text)

femoral augments, and then balanced the flexion gap using different sized femoral components. We retrospectively analyzed 45 patients who had revision total knee replacement with an average of 4 years followup. These patients had a mean flexion of 105 degrees and none had signs of instability in flexion or extension or on clinical exam. Despite the complex nature of revision knee arthroplasty, cases utilizing an algorithm to balance the extension and flexion gaps, with increased implant constraint (...) Flexion and extension gap balancing in revision total knee arthroplasty. Revision total knee arthroplasty presents a unique set of problems when attempting to balance flexion and extension gaps. Loss of soft tissue support and established deformity can make balancing difficult. One needs to balance the flexion and extension gap heights as well as medial and lateral symmetry, which may not always be attainable. We used a set of stepwise techniques to reestablish the joint line in extension using

2006 Clinical Orthopaedics and Related Research

1080. A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee. (Full text)

A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee. To examine the relationship between structural changes of trabecular bone and cartilage, in patients with varying degrees of osteoarthritis (OA) over 2 years, using magnetic resonance imaging.High-resolution, axial images were acquired for assessing trabecular bone structure, using a 3-D fast gradient-echo sequence. High-resolution, fat-suppressed, sagittal (...) (2) increased significantly (P<0.05) between the baseline and follow-up exams for all cartilage compartments except the lateral tibia. A positive relationship was established between cartilage changes and localized bone changes closest to the joint line, while a negative relationship was established between cartilage changes and global bone changes farthest from the joint line.This study quantifies the changes in bone and cartilage structural parameters over time, and demonstrates a longitudinal

2004 Osteoarthritis and Cartilage

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