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Knee Exam

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1001. Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery

Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00633438 Recruitment Status : Completed First Posted : March 12, 2008 Last Update

2008 Clinical Trials

1002. COLOMBES Project:Constitution of a Population-based Cohort of Obese Subjects With Longitudinal Long-term Follow-up

Measures : Rate of follow-up at annual visit [ Time Frame: annual ] Secondary Outcome Measures : Assessment of knee arthrosis (pain and radiological exam), at inclusion and after loss-weight (comparison after one and two years of follow-up of patients that did or did not undergo bariatric surgery). [ Time Frame: one and two years of follow-up ] Biospecimen Retention: Samples With DNA plasma, serum, DNA, RNA, cell blood, for persons undergoing bariatric surgery (specific consentment): samples of liver (...) ) with annual follow-up for 10 years. It aims to improve the physiopathological, epidemiological and prognostic knowledge of obesity and its consequences. Clinical data, biological material, exams and questionaires will be collected and stored, allowing the realisation of research works, initiated by research teams from our hospital or from other settings. Condition or disease Obesity Detailed Description: The objective of this observational study is the follow-up of a cohort of 500 adult persons

2008 Clinical Trials

1003. Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica

, patients and clinicians will have access to a simple, inexpensive therapy that can be prescribed by primary care physicians without delay. This study will determine the effectiveness of the oral steroid prednisone in decreasing pain and improving function in people with sciatica. Participants in this study will attend a screening visit at which they will answer questions about their health to determine eligibility, undergo a neurologic exam, and have a plain lower spine x-ray. An MRI of the lower spine (...) City, or Roseville site Complains of low back pain and functionally incapacitating leg pain extending below the knee with a nerve root distribution Score of at least 20 on the modified Oswestry Disability Index Appears, in the opinion of the study physician, to be very likely to have a herniated lumbar disc MRI study confirms a herniated disc consistent with the signs and symptoms Exclusion Criteria: Onset of sciatica symptoms occurred more than 3 months before study entry Cauda equina syndrome

2008 Clinical Trials

1004. The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome

to quality of life and daytime functioning. Recent surveys indicate that RLS occurs in 10% to 15% of the North American population. A common associated feature of RLS is Periodic Limb Movements during Sleep (PLMS). These are repetitive movements that typically occur as flexions of the foot, knee, and hip at intervals of 5 to 90 seconds. Most commonly, the interval is 20 to 40 seconds. The movements are present during non-rapid-eye-movement (REM) sleep and are less common during REM sleep. Population (...) evidence of substance dependence or abuse as defined by DSM-IV criteria; Regular consumption of large amounts of xanthine-containing substances (i.e. more than 5 cups of coffee or equivalent amounts of xanthine-containing substances per day); Self report of the usual consumption of more than 14 units of alcohol per week; Secondary causes of RLS which will be ruled out by physical exam, medical history and clinical chemistries, including serum ferritin; Use of any investigational drug within 30 days

2008 Clinical Trials

1005. A 72-week Randomized Clinical Trial Comparing the Safety and Efficacy of Three Initial Antiretroviral Regimens -GPO-VIR S (d4T/3TC/NVP) for 24 Weeks Followed by GPO-VIR Z (AZT/3TC/NVP) vs GPO-VIR Z vs TDF/FTC/NVP

as long as the exposure is at least 3 months prior to entry. CD4 < 350 cells/mm3 Subject understands the study and is able to sign informed consent Exclusion Criteria: Evidence of symptomatic persistent symptoms of tingling or numbness of lower extremities and bilateral lower extremity neuropathy on exam at entry. Abnormal exam includes 1) Diminished (compared with the knee) or absent ankle reflexes OR 2) Diminution of either vibration sensation in the legs (defined as perception of vibration for < 10

2008 Clinical Trials

1006. Knee Articular Cartilage Debridement in Conjunction With Partial Meniscectomy

or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 60 Years (Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria:Screening Age between 18 and 60 years BMI <35 Meniscal tear (medial or lateral) diagnosed by H+P exam and/or imaging in the index knee (...) No severe joint space narrowing (IKDC Classification) seen on weight-bearing AP X-ray in the index knee No avascular necrosis in the index knee as evidenced by preop MRI obtained within 6 months prior to randomization No Varus (>10 degrees) or Valgus (>15 degrees)knee deformities as seen by AP X-ray in the index knee Minimal or no abnormality of contralateral knee as shown by clinical exam and/or imaging Candidate for unilateral arthroscopic treatment of the knee Visual Analog Scale (VAS) pain score

2008 Clinical Trials

1007. Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis

, with Pittsburgh Sleep Quality Index > 5 [36]. Exclusion Criteria: Patients with diagnosis of obstructive sleep apnea (OSA). OR, Patients with dense hemiplegia secondary to cerebrovascular accident. OR, NYHA Class III - patients with heart failure condition limited by minimal activity. OR, Severe COPD with shortness of breath at minimal exertion. OR, Peripheral vascular disease with severe claudication. OR, Dementia with Mini Mental Status Exam score of 20 or less. OR, Patients who received knee intra (...) Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Acupuncture for Pain

2008 Clinical Trials

1008. Exercise Intervention to Reduce Postural Instability in Osteoarthritis

to total knee replacement would confound the effect of interventions. Current involvement in physical therapy, since it would confound results. Medically unstable upon exam, i.e. poorly controlled blood pressure or blood sugar, unstable coronary artery disease, since group participation may compromise medical status. Morbid obesity (BMI>40) due to potential changes in gait variables (speed, cadence, stride length). Weight over 300 pounds (due to limitations of Neurocom force plate). Contacts (...) Information provided by (Responsible Party): VA Office of Research and Development ( US Department of Veterans Affairs ) Study Details Study Description Go to Brief Summary: This is a one year pilot study evaluating the feasibility of a 10 week, twice weekly, group functional exercise sessions in individuals with knee osteoarthritis and its effect on gait and balance measures. Condition or disease Intervention/treatment Phase Osteoarthritis Behavioral: functional exercise training Not Applicable Detailed

2008 Clinical Trials

1009. Performance of a non-fluoroscopically assisted substitute for the Lyon schuss knee radiograph: quality and reproducibility of positioning and sensitivity to joint space narrowing in osteoarthritic knees. (Full text)

Performance of a non-fluoroscopically assisted substitute for the Lyon schuss knee radiograph: quality and reproducibility of positioning and sensitivity to joint space narrowing in osteoarthritic knees. This study evaluated the longitudinal performance of a modified Lyon schuss (LS) knee examination in the detection of radiographic joint space narrowing (JSN) in knees with osteoarthritis (OA). The modified LS exam entails two to four iterative acquisitions with empirically adjusted angulation (...) of the X-ray beam to achieve superimposition of the anterior and posterior margins of the medial tibial plateau (MTP), a marker of parallel radioanatomic alignment that the original LS exam achieves with fluoroscopically guided beam angulation.Seventy-four obese women with symptomatic knee OA underwent LS and fixed-flexion (FF, caudal 10 degrees beam angulation) X-ray exams at baseline and 1 year later. For 47 subjects, beam angulation for both LS exams was guided by fluoroscopy. For 27 subjects

2008 Osteoarthritis and Cartilage

1010. A new non-invasive method to assess synovitis severity in relation to symptoms and cartilage volume loss in knee osteoarthritis patients using MRI. (Full text)

, using a 1.5T and a knee coil. For the synovial membrane, the MRI exam included two axial sequences: a T2-weighted (synovial fluid) and a gradient echo (GRE) (synovial membrane). Synovial membrane thickness was measured on four regions of interest (ROI): medial and lateral recesses, and medial and lateral suprapatellar bursa, with each graded/scored from 0 to 3, for a maximum of 12. A validation study was performed on a cohort of 27 knee OA patients having MRI at baseline. A subset of 14 patients had (...) A new non-invasive method to assess synovitis severity in relation to symptoms and cartilage volume loss in knee osteoarthritis patients using MRI. Synovitis in knee osteoarthritis (OA) patients is a significant risk factor for disease progression. This study aimed at developing a magnetic resonance imaging (MRI) scoring system allowing reliable and sensitive assessment of synovitis severity in knee OA patients without the use of a contrast agent.Imaging was performed without contrast agent

2008 Osteoarthritis and Cartilage

1011. Diagnosis of Infected Total Knee: Findings of a Multicenter Database. (Full text)

Diagnosis of Infected Total Knee: Findings of a Multicenter Database. Although total knee arthroplasty (TKA) is an effective and successful procedure, the outcome is occasionally compromised by complications including periprosthetic joint infection (PJI). Accurate and early diagnosis is the first step in effectively managing patients with PJI. At the present time, diagnosis remains dependent on clinical judgment and reliance on standard clinical tests including serologic tests, analysis (...) the current status of diagnosis of the infected TKA utilizing commonly available tests. Intraoperative cultures should not be used as a gold standard for PJI owing to high percentages of false-negative and false-positive cases. When combined with clinical judgment, total white cell count and percentage of neutrophils in the synovial fluid more accurately reflects PJI and when combined with hematologic exams safely excludes or confirms infection.Level II, prognostic study. See Guidelines for Authors

2008 Clinical Orthopaedics and Related Research

1012. Examination of the Spine

Examination of the Spine Examination of the Spine. Information about spine exams. Patient | Patient TOPICS Try our Symptom Checker TREATMENT RESOURCES Try our Symptom Checker PROFESSIONAL Upgrade to Patient Pro / / Search Examination of the Spine Authored by , Reviewed by | Last edited 21 Aug 2014 | Certified by This article is for Medical Professionals Professional Reference articles are designed for health professionals to use. They are written by UK doctors and based on research evidence, UK (...) ) which may suggest neurofibromatosis, a fat pad or hairy patch suggestive of spina bifida, or scarring suggestive of previous thoracotomy or spinal surgery. Functional overlay: Ask the patient to sit up on the couch. A genuine patient will have to flex the knees or they will fall back on the couch with pain. Axial loading: apply pressure to the head. Overlay is suggested if this aggravates the back pain. Palpation Check for bone tenderness of the spine: tenderness may indicate serious pathology

2008 Mentor

1013. Postnatal care up to 8 weeks after birth

should be evaluated (urgent action). [2006] [2006] Postnatal care up to 8 weeks after birth (CG37) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 31 of 63Colic Colic 1.4.34 A baby who is crying excessively and inconsolably, most often during the evening, either drawing its knees up to its abdomen or arching its back, should be assessed for an underlying cause, including infant colic (urgent action). [2006] [2006

2006 National Institute for Health and Clinical Excellence - Clinical Guidelines

1014. Usefulness of Kernig and Brudzinski Signs in Diagnosing Meningitis

. Which is why it’s so timely that we review meningitis, with a focus on some physical exam skills that can (but may not) help guide your diagnosis. Tim reviewed a paper by Thomas et al out of Yale, published in Clinical Infectious Diseases (2002;Vol 35 July 1, pp46-52) called “The Diagnostic Accuracy of Kernig’s Sign, Bruzinski’s Sign, and Nuchal Rigidity in Adults with Suspected Meningitis.” Here’s his . The researchers looked at anyone over 16 who presented to Yale-New Haven with “clinically (...) suspected meningitis” (which they define as headache, fever, stiff neck, photophobia, nausea + vomiting) who were tapped. This was part of a larger cohort used in other studies. 301 were enrolled, 297 were tapped (four had CT’s that showed mass effect). Physicians (28% interns, 55% residents, and 17% attendings) were required to document their history and exam findings before LP, but were NOT instructed on how to properly test Kernig’s and Brudzinski’s signs. Meningitis was considered to be present

2006 Sinai EM Journal Club

1016. Prevention of Constipation in the Older Adult Population

is highly recommended. 9.0 Promote regular consistent toileting each day based on the client’s triggering III meal. Safeguard the client’s visual and auditory privacy when toileting. 9.1 A squat position should be used to facilitate the defecation process. For clients III who are unable to use the toilet (e.g., bed-bound) simulate the squat position by placing the client in left-side lying position while bending the knees and moving the legs toward the abdomen. *See page 12 for details regarding (...) strength, bowel sounds, abdominal mass, constipation/fecal impaction, hemorrhoids and intact anal reflex. (Level of Evidence = IV) Discussion of Evidence Clinical and expert opinion supports that an appropriate physical assessment includes inspection, auscultation, palpation and percussion of the abdomen to assess functioning of the intestine. A rectal exam is used to assess both the functioning of the anal sphincter and for the presence of fecal matter in the lower rectum. Episodes of acute

2005 Registered Nurses' Association of Ontario

1017. Bedside Rounds: What is Lasegue's Sign?

Bedside Rounds: What is Lasegue's Sign? Bedside Rounds: What is Lasegue’s Sign? – Clinical Correlations Search Bedside Rounds: What is Lasegue’s Sign? July 10, 2007 2 min read Commentary by Judith Brenner MD, Associate Program Director, NYU Internal Medicine Residency Program A 66 year old woman with a history of dyslipidemia and remote tobacco use presents with a sudden onset of pain located in her posterior left thigh radiating down her left leg below the knee. The pain began during (...) presented, the patient reports the sudden onset of radicular pain in a setting where acute disc herniation is likely. On exam, findings of any of the above mentioned signs would make the diagnosis more likely. In order to localize further, one would perform a sensory exam or a more comprehensive motor exam. In this case, the patient did indeed have a disc herniation at L5/S1, verified on MRI. She was treated with analgesics, including Tylenol #3 for 3 weeks, and began physical therapy as her pain began

2007 Clinical Correlations

1018. Risk Assessment and Prevention of Pressure Ulcers

for assessment (AHCPR, 1992; Consortium for Spinal Cord Medicine, 2000; Royal College of Nursing, 2000; Weir, 2001). Skin inspection should be based on a head-to-toe assessment of those areas known to be vulnerable for each patient. These areas typically include the temporal region and occiput of the skull, ears, scapulae, spinous processes, shoulders, elbows, sacrum, coccyx, ischial tuberosities, trochanters, knees, malleoli, metatarsal areas, heels, and the toes. In addition, areas of the body covered

2002 Registered Nurses' Association of Ontario

1019. The Practical Guide: Identification, Evaluation, and Treatment of Overweight and Obesity in Adults

evaluation should be performed on an obese patient starting a weight loss regimen if this has not been done within the past year. The medical history and physical exam should focus on causes and complications of obesity. BMI should be calculated and waist circumference measured to better assess risk and to offer measures of outcome in addition to weight loss. Although the causes of obesity are not fully known, certain factors clearly play a role. Family history is important because of the strong (...) find that they can sleep comfortably only in the sit- ting position. The patient’s partner may best describe these symptoms. Daytime fatigue, with episodes of sleepiness at inappropriate times, and morning headaches also occur. On exam, hypertension, narrowing of the upper airway, scleral injec- tion, and leg edema, secondary to pulmonary hypertension, may be observed. Laboratory studies may show polycythemia. If signs of sleep apnea are present, referral to a pulmonologist, or sleep specialist

2000 The Obesity Society

1020. Trial of a Home Based Strength and Balance Retraining Program in Reducing Falls Risk Factors

by the Physiological Profile Assessment (PPA) and its five components (vision, reaction time, knee extension strength, proprioception, sway) [ Time Frame: 12 months ] Secondary Outcome Measures : Fear of falling, cost, injurious falls, Physiologic Profile Assessment (overall score and subcomponents), cognitive performance based on standard neuropsychological tests, and everyday function. All measured at 6 and 12 months [ Time Frame: 12 months ] Biospecimen Retention: None Retained None retained Eligibility (...) Healthy Volunteers: Yes Sampling Method: Probability Sample Study Population Seniors aged 70 years and older, presenting to a health care provider with a fall. Criteria Inclusion Criteria: Aged 70 years and older, present to a health care provider with a fall, mini mental state exam of at least 24 Exclusion Criteria: Progressive neurological condition, medical condition precluding participation in physical activity, residing in a nursing home/extended care facility Contacts and Locations Go

2006 Clinical Trials

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