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Knee Exam

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61. Study to Determine the Efficacy and Effectiveness of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee

between 18.5 and 40 KL Grade 2 or 3 knee OA OARSI Grade 1 or 2 medial JSN Pain >= 40 on VAS scale WOMAC score <=70 for target knee Written informed consent Using birth control Exclusion Criteria: Knee symptoms that result in difficulty or inability to walk Knee effusion >2+ Has Grade 0 OARSI JSN or atrophic OA MRI exam indicates fracture or tumor Has taken NSAIDS with 14 days of baseline Has taken steroidal anti-inflammatory medication within 2 months of baseline Currently using topical analgesics (...) to the target knee within 12 months of screening Active ulcer or infection on the skin of the target knee within 1 month of screening Surgery on the target knee within 6 months of screening Varus or valgus of the target knee >10 degrees Has total knee arthroplasty or other knee surgery planned within the next 12 months. Participation in another investigation study within 3 months Unable to complete requisite follow-up and 3T MRI exams Has cognitive impairment or cannot otherwise provide informed consent

2017 Clinical Trials

62. Impact of Powered Knee-Ankle Prosthesis Leg on Everyday Community Mobility and Social Interaction

Impact of Powered Knee-Ankle Prosthesis Leg on Everyday Community Mobility and Social Interaction Impact of Powered Knee-Ankle Prosthesis Leg on Everyday Community Mobility and Social Interaction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Impact of Powered Knee-Ankle Prosthesis Leg on Everyday Community Mobility and Social Interaction The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03204513 Recruitment Status

2017 Clinical Trials

63. Ultrasound Guided Knee Injections in Musculoskeletal Medicine

: Suprapatellar Landmark Patients will be lying supine on exam table. Injecting physician will insert needle lateral to the vastus lateralis toward the suprapatellar pouch, and will inject of Euflexxa once it is believed that the needle tip is in the pouch. Other Name: SPL Outcome Measures Go to Primary Outcome Measures : Radiology Assessment Outcome [ Time Frame: Procedure visit 3 (3-4 weeks after 1st injection) ] To assess presence or absence of contrast medium within the target knee joint as determined (...) Ultrasound Guided Knee Injections in Musculoskeletal Medicine Ultrasound Guided Knee Injections in Musculoskeletal Medicine - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Ultrasound Guided Knee Injections

2017 Clinical Trials

64. Intra-Articular Platelet Rich Plasm Use in Osteoarthritis of Knee.

Intra-Articular Platelet Rich Plasm Use in Osteoarthritis of Knee. Intra-Articular Platelet Rich Plasm Use in Osteoarthritis of Knee. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Intra-Articular Platelet (...) Rich Plasm Use in Osteoarthritis of Knee. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03086759 Recruitment Status : Completed First Posted : March 22, 2017 Last Update Posted : January 18, 2019 Sponsor: Federal University of São Paulo Information provided by (Responsible Party): Jose Carlos

2017 Clinical Trials

65. The Effects of Stromal Vascular Fraction and Mesenchymal Stem Cells as Intra-articular Injection in Knee Joint Osteoarthritis

The Effects of Stromal Vascular Fraction and Mesenchymal Stem Cells as Intra-articular Injection in Knee Joint Osteoarthritis The Effects of Stromal Vascular Fraction and Mesenchymal Stem Cells as Intra-articular Injection in Knee Joint Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. The Effects of Stromal Vascular Fraction and Mesenchymal Stem Cells as Intra-articular Injection in Knee Joint Osteoarthritis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our

2017 Clinical Trials

66. Sinew Acupuncture for Knee Osteoarthritis

aims to exam whether sinew acupuncture can relieve pain and symptoms of KOA and improve functional movement by Visual Analog Scale (VAS), Western Ontario and McMasters University Osteoarthritis Index (WOMAC), Timed up & Go Test (TUG) and 8-step Stair Climb Test (SCT) assessment, and Quality of life by Short Form-36 (SF-36). A randomized, sham acupuncture controlled, patient and assessor blinded, pilot study will be employed. Condition or disease Intervention/treatment Phase Knee Osteoarthritis (...) Sinew Acupuncture for Knee Osteoarthritis Sinew Acupuncture for Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Sinew Acupuncture for Knee Osteoarthritis The safety and scientific

2017 Clinical Trials

67. Validity evidence for two objective structured clinical examination stations to evaluate core skills of the shoulder and knee assessment (PubMed)

Validity evidence for two objective structured clinical examination stations to evaluate core skills of the shoulder and knee assessment We developed two objective structured clinical examinations (OSCEs) to educate and evaluate trainees in the evaluation and management of shoulder and knee pain. Our objective was to examine the evidence for validity of these OSCEs.A multidisciplinary team of content experts developed checklists of exam maneuvers and criteria to guide rater observations (...) coefficient.A multi-disciplinary cohort of 69 examinees participated. Examinees correctly identified rotator cuff and meniscal disease 88% and 89% of the time, respectively. Inter-rater agreement was moderate for the knee (87%; k = 0.61) and near perfect for the shoulder (97%; k = 0.88). No correlation between stratified self-assessment and OSCE scores were found for either shoulder (0.02) or knee (-0.07).Validity evidence supports the continuing use of these OSCEs in educational programs addressing

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2017 BMC medical education

68. Revision Total Knee Arthroplasty with Metaphyseal Sleeves without Stem: Short-Term Results (PubMed)

available for the study. Mean follow-up was 37 months. Knee Society score (KSS) (objective knee score), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, and range of motion (ROM) were used as outcome scores and compared with baseline values. X-rays were also examined and compared with postoperative exams to evaluate the presence of loosening, radiolucent lines, and bone ingrowth. Satisfaction of the patients was also investigated using a linear scale from 1 to 10. Results (...) Revision Total Knee Arthroplasty with Metaphyseal Sleeves without Stem: Short-Term Results Purpose  The aim of this study was to evaluate the efficacy of revision total knee arthroplasty (TKA) with cementless metaphyseal sleeves without stems either in the femoral or tibial side or in both. Methods  In this retrospective study, 51 patients (51 knees) operated in the period 2010 to 2015 met the above-mentioned criteria and were invited to a medical examination including X-rays. Forty-six were

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2017 Joints

69. The Anatomic Relationship of the Tibial Nerve to the Common Peroneal Nerve in the Popliteal Fossa: Implications for Selective Tibial Nerve Block in Total Knee Arthroplasty (PubMed)

, after the ultrasound-guided dye injection the dissection revealed proximal spread of dye within the paraneural sheath. Consequentially, in the clinical study twenty patients scheduled for total knee arthroplasty received the ultrasound-guided selective tibial nerve block at the popliteal crease, which also resulted in proximal spread of local anesthetic. A sensorimotor exam was performed to monitor the effect on the peroneal nerve. Results. In the cadaver study, dye was observed to spread proximal (...) The Anatomic Relationship of the Tibial Nerve to the Common Peroneal Nerve in the Popliteal Fossa: Implications for Selective Tibial Nerve Block in Total Knee Arthroplasty Background. A recently described selective tibial nerve block at the popliteal crease presents a viable alternative to sciatic nerve block for patients undergoing total knee arthroplasty. In this two-part investigation, we describe the effects of a tibial nerve block at the popliteal crease. Methods. In embalmed cadavers

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2017 Pain research & management

70. Recommendations for the Use of Nonpharmacologic and Pharmacologic Therapies in Osteoarthritis of the Hand, Hip, and Knee

analgesics * No strong recommendations were made for the initial pharmaco- logic management of hip osteoarthritis (OA). For patients who have an inadequate response to initial pharmacologic management, please see the Results for alternative strategies. NSAIDs non- steroidal antiin?ammatory drugs. 2012 ACR Recommendations for Management of Hand, Hip, and Knee OA 471with disagreement by health care practitioners. One exam- ple is that of conditionally recommending against the use of glucosamine (...) Recommendations for the Use of Nonpharmacologic and Pharmacologic Therapies in Osteoarthritis of the Hand, Hip, and Knee American College of Rheumatology 2012 Recommendations for the Use of Nonpharmacologic and Pharmacologic Therapies in Osteoarthritis of the Hand, Hip, and Knee MARC C. HOCHBERG, 1 ROY D. ALTMAN, 2 KARINE TOUPIN APRIL, 3 MARIA BENKHALTI, 3 GORDON GUYATT, 4 JESSIE MCGOWAN, 3 TANVEER TOWHEED, 5 VIVIAN WELCH, 3 GEORGE WELLS, 3 AND PETER TUGWELL 3 Guidelines and recommendations

2012 American College of Rheumatology

71. Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery

Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02807428 Recruitment Status : Completed First

2016 Clinical Trials

72. Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN

the eligibility of the patients. Eligible patients will sign an informed consent. The investigator will make a general evaluation (demography, medical history, OA history, OA medication history, concomitant medications including "rescue treatments") and a pain evaluation. Synovial fluid will be collected in case of knee swelling. Blood samples will be collected in a preselected clinical laboratory for future biomarkers analyses. Patients will be asked to perform an MRI exam within 20 days following (...) Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have

2016 Clinical Trials

73. Long-Term Effectiveness of Walking Training in Patients With Knee Osteoarthritis

Recurrent giving way of the knee Symptoms arising primarily from a meniscal or ligament pathology or other structure not directly related to osteoarthritis as identified by physical exam, health record, or MRI Symptoms originating primarily from the patellofemoral joint Avascular necrosis Recent (within two months) knee injury or surgery Planned use of hinged knee brace in next 12 months Severe knee malalignment of more than 10 degrees from neutral Intra-articular injection within the past 2 months (...) Long-Term Effectiveness of Walking Training in Patients With Knee Osteoarthritis Long-Term Effectiveness of Walking Training in Patients With Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding

2016 Clinical Trials

74. Osteochondritis Dissecans of Knee Prospective Cohort

. At follow-up visits, surgeons will complete their own physical exam follow-up assessment forms, which will be collected. Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 3000 participants Observational Model: Cohort Time Perspective: Prospective Official Title: ROCK Comprehensive Prospective Cohort for Osteochondritis Dissecans of the Knee Study Start Date : May 2014 Estimated Primary Completion Date : May 2064 Estimated Study Completion Date (...) Osteochondritis Dissecans of Knee Prospective Cohort Osteochondritis Dissecans of Knee Prospective Cohort - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Osteochondritis Dissecans of Knee Prospective Cohort

2016 Clinical Trials

75. Imaging Biomarkers of Knee Osteoarthritis

topics: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: High Risk for Osteoarthritis "High risk of developing knee OA" has been defined by having knee pain but normal radiographs (Kellgren-Lawrence score 0 i.e. KL0) on both knees but at least one abnormal finding on clinical MR protocol such as overweight, prior knee injury (ligaments or menisci) or traumatic bone marrow edema lesions. Device: PRISMA 3T MRI scanner (Siemens Medical Solutions) A baseline MRI exam consisting (...) of accelerated 3D-T1p, and T2, MRI will be performed. Longitudinal follow-up MRI exams (24 months) will be repeated on the same knee on all OA patients. Active Comparator: Mild Osteoarthritis Device: PRISMA 3T MRI scanner (Siemens Medical Solutions) A baseline MRI exam consisting of accelerated 3D-T1p, and T2, MRI will be performed. Longitudinal follow-up MRI exams (24 months) will be repeated on the same knee on all OA patients. Active Comparator: Healthy Controls Controls will be age/gender matched

2016 Clinical Trials

76. Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial

for follow-up visit at 12 weeks for a physical exam of the knee. Patients will fill out questionnaires online at 1, 6, 12 and 24 weeks. Drug: 40 mg Depo-Medrol in 1 ml, 9 ml of 1% lidocaine Patients will receive an ultrasound guided intra-articular injection of 40 mg Depo-Medrol in 1 ml, 9 ml of 1% lidocaine Other Name: Corticosteroid Placebo Comparator: Knee injection with saline Using clinically accepted methods, subjects will undergo a palpation guided injection of saline into the knee joint. Subjects (...) will then return for follow-up visit at 12 weeks for a physical exam of the knee. Patients will fill out questionnaires online at 1, 6, 12 and 24 weeks. Drug: Normal Saline 10 ml Patients will receive an ultrasound guided intra-articular injection of Normal Saline 10 ml Other Name: Saline Sham Comparator: Knee injection with air Using clinically accepted methods, subjects will undergo a palpation guided injection of air into the knee joint. Subjects will then return for follow-up visit at 12 weeks

2016 Clinical Trials

77. Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty

Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Mepivacaine (...) vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02980926 Recruitment Status : Completed First Posted : December 2, 2016 Last Update Posted : March 27, 2017 Sponsor: Henry Ford Health System Information provided by (Responsible Party): M

2016 Clinical Trials

78. HyaloFAST Trial for Repair of Articular Cartilage in the Knee

HyaloFAST Trial for Repair of Articular Cartilage in the Knee HyaloFAST Trial for Repair of Articular Cartilage in the Knee - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. HyaloFAST Trial for Repair (...) of Articular Cartilage in the Knee (FastTRACK) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT02659215 Recruitment Status : Recruiting First Posted : January 20, 2016 Last Update Posted : September 26, 2018 See Sponsor: Anika

2016 Clinical Trials

79. Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee.

Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee. Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02709486 Recruitment Status : Completed First

2016 Clinical Trials

80. Dartmouth-Hitchcock GreenCare Registry for Total Knee Replacement

to 1-year following surgery in the Physical Component Summary (PCS) of the Veterans-Rand (VR-12) Survey. Preoperative measures were: (1) general demographics (patient age, sex, height, weight, body mass index (BMI); (2) treatments tried before surgery; (3) health habits (tobacco use, alcohol use); (4) pre-existing medical conditions (Charlson score); (5) physical exam findings (knee range of motion, knee laxity); (7) lab tests (hemoglobin); and (7) radiographic measures (severity of osteoarthritis (...) Dartmouth-Hitchcock GreenCare Registry for Total Knee Replacement Dartmouth-Hitchcock GreenCare Registry for Total Knee Replacement - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Dartmouth-Hitchcock

2016 Clinical Trials

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