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Knee Exam

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41. Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis

Years to 70 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Ability to provide informed consent Chronic pain (>3 months) Grade 2 -3 according to Kellgren- Lawrence (K-L) classification system (using bilateral anteroposterior radiograph image acquired while the patient is weight-bearing with both knees in full extension) Minimum score of 40 out of possible 100 on the VAS for pain Age 18 to 70 years old Physical exam and medical (...) Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2018 Clinical Trials

42. A Study to Assess Efficacy and Safety of GLPG1972/S201086 in Patients With Knee Osteoarthritis

or planned during the study. Other pathologies affecting the knee. Any contraindication to MRI including the inability to undergo a knee MRI exam because of inability to fit in the scanner or knee coil. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number (...) A Study to Assess Efficacy and Safety of GLPG1972/S201086 in Patients With Knee Osteoarthritis A Study to Assess Efficacy and Safety of GLPG1972/S201086 in Patients With Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

43. Evaluating the Effectiveness of Subchondroplasty for Treating Bone Marrow Lesions of the Knee

: 40 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: 40 years of age or older Kellgren-Lawrence grade 1-3 osteoarthritis in the affected knee Has experienced pain in the affected knee for at least 3 months Candidate for knee arthroscopy (moderate to severe symptoms, lack of response to non-operative care, and/or mechanical symptoms) Stable ligament exam No additional injuries affecting the study knee or contralateral (...) Evaluating the Effectiveness of Subchondroplasty for Treating Bone Marrow Lesions of the Knee Evaluating the Effectiveness of Subchondroplasty for Treating Bone Marrow Lesions of the Knee - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

44. Clinical and radiologic evaluation of the posterior cruciate ligament-injured knee (PubMed)

. Any thorough exam should compare the contralateral, uninjured leg. If a PCL or multi-ligament injury is suspected, plain radiographs should be performed to avoid missing a fracture or avulsion. An MRI represents the current gold standard for diagnosing ligament injuries in the knee and should always be obtained in these cases. Due to the significant incidence of nerve injuries (25%) and vascular injuries (18%) with knee dislocations, any suspicion of neurovascular compromise necessitates further (...) Clinical and radiologic evaluation of the posterior cruciate ligament-injured knee Accurate isolated PCL diagnosis continues to present a challenge. This article reviews the current literature regarding clinical and radiographic evaluation of PCL injuries.A thorough history to understand the mechanism of injury should begin any evaluation. Several clinical tests have been shown to effectively assess PCL laxity, with the posterior drawer test possessing the highest sensitivity and specificity

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2018 Current reviews in musculoskeletal medicine

45. Statin use and knee osteoarthritis outcomes: A longitudinal cohort study. (PubMed)

-up for 4 years. Statins use (including the time from baseline and the type) was defined through self-report information and confirmed by a trained interviewer. Knee OA outcomes included incident (1) ROA, (2) SxOA, as the new onset of a combination of a painful knee and ROA, (3) knee pain worsening, i.e. a Western Ontario and McMaster Universities Osteoarthritis Index difference between baseline and each annual exam ≥14%.At baseline, 1,127 participants (=25.3%) used statins. Based (...) Statin use and knee osteoarthritis outcomes: A longitudinal cohort study. Statins have several pleiotropic effects, but the literature regarding the possible relationship between statins use and outcomes in knee osteoarthritis (OA) is limited. We investigated whether statins use is associated with lower risk of radiographic (ROA), radiographic symptomatic knee OA (SxOA) and pain in North American people.A total of 4,448 community-dwelling adults from the Osteoarthritis Initiative were followed

2018 Arthritis care & research

46. Factors predictive of poorer outcomes in the surgical repair of multiligament knee injuries. (PubMed)

Factors predictive of poorer outcomes in the surgical repair of multiligament knee injuries. To investigate the influence of injury and treatment factors on clinical/functional outcomes in multiligament knee injuries (MLKI).Thirty-nine consecutive patients with confirmed and surgically treated MLKI who met inclusion criteria were scheduled for a follow-up visit to obtain: SF-12 and subjective feeling of normalcy between the operated and healthy knee, and IKDC, active range of motion (ROM (...) ), and stability exam (Lachman test, posterior drawer, and dial test at 30°). A chart review was used to obtain data on injury and treatment factors.The postoperative mean (SD) outcomes were: IKDC score 62.7 (25.9), flexion-extension ROM 125° (29°), and percentage of normalcy 74% (20%). The postoperative normal/nearly normal stability exam was: Lachman test 36 (95%) patients, posterior drawer at 90° 38 (97%) patients, and dial test of 39 (100%) patients. There were 24 (61.5%) and 23 (59%) patients

2018 Knee Surgery, Sports Traumatology, Arthroscopy

47. Mediterranean diet and knee osteoarthritis outcomes: A longitudinal cohort study. (PubMed)

at high risk or having knee OA.Adherence to the Mediterranean diet was evaluated using a validated Mediterranean diet score (aMED), categorized in five categories (Q1 to Q5, higher values reflecting higher adherence to Mediterranean diet). Knee OA outcomes included incident (1) ROA, (2) SxOA, as the new onset of a combination of a painful knee and ROA, (3) knee pain worsening, i.e. a Western Ontario and McMaster Universities Osteoarthritis Index difference between baseline and each annual exam of ≥14 (...) Mediterranean diet and knee osteoarthritis outcomes: A longitudinal cohort study. Mediterranean diet has several beneficial effects on health, but data regarding the association between Mediterranean diet and knee osteoarthritis (OA) are limited mainly to cross-sectional studies. We investigated whether higher Mediterranean diet adherence is prospectively associated with lower risk of radiographic OA (ROA), radiographic symptomatic knee OA (SxOA) and pain worsening in North American people

2018 Clinical nutrition (Edinburgh, Scotland)

48. Anterolateral ligament injuries in knees with an anterior cruciate ligament tear: Contribution of ultrasonography and MRI. (PubMed)

Anterolateral ligament injuries in knees with an anterior cruciate ligament tear: Contribution of ultrasonography and MRI. To describe the pathological appearance of the anterolateral ligament (ALL) on US and MRI in knees with an anterior cruciate ligament (ACL) tear.This prospective study included 30 patients who had a suspected acute ACL tear. Their injured and contralateral knees were evaluated with radiography, US and MRI. Two radiologists evaluated the ALL on the MRI and US examinations (...) . Agreement between these examiners' findings was evaluated with Cohen's kappa.On US examination, the ALL was found to be injured in 63% of cases (19/30; k = 0.93). The enthesis was found to be torn in 50% of cases (15/30; k = 1), with the tear located at the tibial attachment in all instances. On the MRI exam, the ALL was found to be injured in 53% of cases (16/30; k = 0.93). The enthesis was found to be torn in 13% of cases (4/30; k = 0.76), with the tear located at the tibial attachment in all

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2018 European radiology Controlled trial quality: uncertain

49. The effect of tourniquet usage on cement penetration in total knee arthroplasty: A prospective randomized study of 3 methods. (PubMed)

The effect of tourniquet usage on cement penetration in total knee arthroplasty: A prospective randomized study of 3 methods. It is a randomized study to compare cement penetration on x-rays after total knee arthroplasty (TKA) among 3 different ways to use tourniquets; application during the surgery, application only with implantation prosthesis and with no tourniquet use.A total 69 knees of 59 patients were included in the study in a quasirandom manner. Each patient had physical exams (...) and standard radiographic evaluations at 6 weeks after the TKA procedure. Outcome evaluations included visual analog scale (VAS) scores, Knee Society Scores (KSS), blood transfusion, and drainage status after surgery for all groups. For radiographic review, the tibial plateau was divided into zones in the anterior-posterior and lateral views, according to the Knee Society Scoring System.The average age of the patients who were eligible for the study was 65.05 (range 46-81) years. All 59 patients included

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2018 Medicine Controlled trial quality: uncertain

50. Persona Partial Knee Clinical Outcomes Study

, Layout table for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patient is at least 18 years of age Patient qualifies for knee arthroplasty based upon physical exam and medical history, and meets the approved indications for use of the Persona Partial Knee system. Patient has participated in a study-related Informed Consent process Patient is willing and able to provide (...) Persona Partial Knee Clinical Outcomes Study Persona Partial Knee Clinical Outcomes Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Persona Partial Knee Clinical Outcomes Study The safety

2017 Clinical Trials

51. Severe Medial Knee Pain Explained: The Terrible Triad

degenerative knee. A straightforward arthroscopy is not usually successful in the long term in these instances. It would depend on your exam … but you might be correct. Bone marrow edema is often the cause of pain, and an arthroscopy will not address that since it is due to the arthritic changes. Good Luck Aloha Dr. Luks, I am 67 and have run for over 30 years. Three years ago a surgeon said I needed a knee replacement. I didn’t have it and now have a new problem. I had an X-ray, then an MRI of my left (...) Severe Medial Knee Pain Explained: The Terrible Triad Severe Knee Pain Explained: The True Terrible Triad | Search for: Severe Medial Knee Pain Explained: The Terrible Triad Last Updated April 11, 2018 by Howard J. Luks, MD (Radial tear) of the medial meniscus mild or moderate knee arthritis n inner part of the knee. Those three findings on your MRI are related to one another… one caused the next to occur and so on. This is what I refer to as the Terrible Triad of (medial) knee pain

2017 Howard J. Luks, MD blog

52. Quantitative Regional and Sub-Regional Analysis of Femoral and Tibial Subchondral Bone Mineral Density Using Computed Tomography: Comparison of Non-Osteoarthritic and Severe Osteoarthritic Knees. (PubMed)

Quantitative Regional and Sub-Regional Analysis of Femoral and Tibial Subchondral Bone Mineral Density Using Computed Tomography: Comparison of Non-Osteoarthritic and Severe Osteoarthritic Knees. This study aimed to compare subchondral bone mineral density (sBMD) between non-radiographic osteoarthritic (OA) and medial femorotibial OA knees, using computed tomography (CT).CT exams from 16 non-radiographic OA (KL grade < 2) and 16 severe medial OA (KL grade ≥ 3) knees (average age of 61.7 ± 3 (...) and 62.2 ± 5 years old respectively, 50% male in each group), were retrospectively analyzed. CT exams were segmented and 3D maps of sBMD based on the CT number in the most superficial 3 mm of femoral and tibial subchondral bone were computed. Average sBMD and medial-to-lateral sBMD ratios were calculated for total load-bearing regions and for sub-regions of interest in the femur and tibia.The analysis of total load-bearing regions did not reveal any significant difference between groups, except

2017 Osteoarthritis and Cartilage

53. Primary Care Corner with Geoffrey Modest MD: Symptomatic Knee Effusions from OA Resolve With Spironolactone?!

Primary Care Corner with Geoffrey Modest MD: Symptomatic Knee Effusions from OA Resolve With Spironolactone?! Primary Care Corner with Geoffrey Modest MD: Symptomatic Knee Effusions from OA Resolve With Spironolactone?! | BMJ EBM Spotlight by By Dr. Geoffrey Modest And so the wonder drug spironolactone seems to have another possible indication: knee effusions from osteoarthritis (see Elsaman AM. J Rheumatol 2016; 43: 1114). Details: 200 patients with unilateral knee effusion related (...) to osteoarthritis (OA) based on clinical exam, ultrasound and synovial fluid analysis Mean age 51, 40% male, weight 84 kg, mean duration of effusion 16.5 days, mean thickness of fluid by ultrasound was 7.6 mm thick Randomized to 2 weeks of: spironolactone 25 mg daily; ibuprofen 400 mg three times/d; cold compresses twice a day, for 10 minutes each time; or placebo Assessment: effusion considered if >4mm fluid; complete improvement if <4mm, partial improvement if a decrease but still >4mm Results: At 2 weeks

2016 Evidence-Based Medicine blog

54. The Effect of Powered-Knee Exoskeleton Assist on Stair Climbing in Acute CVA

The Effect of Powered-Knee Exoskeleton Assist on Stair Climbing in Acute CVA The Effect of Powered-Knee Exoskeleton Assist on Stair Climbing in Acute CVA - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . The Effect of Powered-Knee Exoskeleton Assist on Stair Climbing in Acute CVA The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03264235 Recruitment Status : Recruiting First Posted : August 29, 2017 Last Update Posted : February

2017 Clinical Trials

55. Evaluation of Fixation Achievable in Revision Total Knee Arthroplasty Implementing Latest-Generation Implant Technology

. Device: Short-Stemmed with Augmented Fixation Short-stemmed primary implant with augmented fixation for total knee arthroplasty Outcome Measures Go to Primary Outcome Measures : Implant Migration Over Time [ Time Frame: 0-2 weeks (baseline exam) to 1 year ] Tibial component migration over time measured through radiostereometric analysis Secondary Outcome Measures : Inducible displacement of the tibial component [ Time Frame: Pre-operatively, 6 weeks, 3 months, 6 months, 1 year, and 2 years (...) Evaluation of Fixation Achievable in Revision Total Knee Arthroplasty Implementing Latest-Generation Implant Technology Evaluation of Fixation Achievable in Revision Total Knee Arthroplasty Implementing Latest-Generation Implant Technology - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2017 Clinical Trials

56. A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee

: Knee symptoms that result in difficulty or inability to walk Knee effusion >2+ Has Grade 0 OARSI JSN or atrophic OA Has a score of >=5 on the cartilege feature of the WORMS at Screening MRI exam indicates fracture or tumor Has a positive result on RCR testing at Screening Has taken NSAIDS with 14 days of baseline Has taken steroidal anti-inflammatory medication within 2 months of baseline Currently using topical analgesics on target knee Chronic (>21 days) narcotic use Recent history (within 1 year (...) Major injury to the target knee within 12 months of screening Active ulcer or infection on the skin of the target knee within 1 month of screening Surgery on the target knee within 6 months of screening Valgus or varus of the target knee >10 degrees Has total knee arthroplasty or other knee surgery planned within the next 12 months. Participation in another investigation study within 3 months Unable to complete requisite follow-up and 3T MRI exams Has cognitive impairment or cannot otherwise provide

2017 Clinical Trials

57. Performance of MOTO Medial® Unicompartmental Knee Arthroplasty

disease in the affected knee compliant with the FDA-approved indications for use of MOTO Medial® UKA. Must have had no prior arthroplasty to the medial compartment of the study knee. Subjects must be able to return for the follow-up appointments, and have the mental capacity to cooperate and complete Patient Reported Outcome questionnaires, physical exam and radiographs. Exclusion Criteria: Knee ligament instability (deficiency of cruciate or collateral ligaments) Inflammatory Arthritis History (...) Performance of MOTO Medial® Unicompartmental Knee Arthroplasty Performance of MOTO Medial® Unicompartmental Knee Arthroplasty - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Performance of MOTO Medial®

2017 Clinical Trials

58. Establish Implant Accuracy With X-PSI Knee System

will be evaluated with an efficiency matrix to record OR set-up time, surgery time and post-processing time. Clinical outcome data of the patients will be evaluated 4-6 weeks and 1 year post-surgery with the help of patient questionnaires (VAS pain scale, EQ-5D and Oxford Knee Score), a physical exam and the assessment of radiographs. The study population will be compromised of males and females requiring total knee arthroplasty and satisfy the inclusion/exclusion criteria. The study will last one (1) year from (...) Establish Implant Accuracy With X-PSI Knee System Establish Implant Accuracy With X-PSI Knee System - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Establish Implant Accuracy With X-PSI Knee System (X-PSI

2017 Clinical Trials

59. Conservative management of MRI-confirmed knee osteoarthritis with instrument-assisted soft-tissue mobilization, joint manipulation, and platelet-rich plasma (PubMed)

Conservative management of MRI-confirmed knee osteoarthritis with instrument-assisted soft-tissue mobilization, joint manipulation, and platelet-rich plasma To describe the successful conservative management of a patient with chronic degenerative knee pain.An active 47 year-old female office-worker with intermittent right knee pain inferolateral to the right patella for eight months described difficulty ascending stairs, sitting on a chair for one hour, and squatting. A physical exam led

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2017 The Journal of the Canadian Chiropractic Association

60. Tissue Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty

Tissue Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty Tissue Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Tissue (...) Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03289247 Recruitment Status : Completed First Posted : September 20, 2017 Last Update Posted : January 25, 2019 Sponsor: Hvidovre University Hospital Information provided by (Responsible

2017 Clinical Trials

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