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Intravenous Drug Abuse

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1. Multidimensional Family Therapy (MDFT) for Young People in Treatment for Non?opioid Drug Abuse: A Systematic Review Full Text available with Trip Pro

Multidimensional Family Therapy (MDFT) for Young People in Treatment for Non?opioid Drug Abuse: A Systematic Review Multidimensional Family Therapy (MDFT) for Young People in Treatment for Non‐opioid Drug Abuse: A Systematic Review - Filges - 2015 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Multidimensional Family Therapy (MDFT (...) treatment is that it is not clear what works best and for whom as the research suggests that a number of interventions lead to reduced drug abuse ( ). Treatments identified as promising are individually based cognitive and motivational therapies including Cognitive Behavioral Therapy, Multisystemic Therapy, and Family therapies ( ; ; ; ). Family therapy covers a range of different interventions, and is based on different manuals and varying theoretical sources such as behavioral and cognitive behavioral

2015 Campbell Collaboration

2. Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients

be experiencing toxicity from them. Tier III tests can also be examined when they are clin- ically indicated, either by history of use, medication list, or very high probability of misuse/abuse, in a specific patient rather than for every patient. Frequency of laboratory testing CONSENSUS-BASED EXPERT OPINION #1: Based on level II evidence, baseline drug testing should be performed prior to initiation of acute or chronic controlled substance therapy. In addition, random drug testing should be performed (...) Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients LABORATORY MEDICINE PRACTICE GUIDELINES EDITED BY LORALIE J. LANGMAN AND PAUL J. JANNETTO Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Co-Sponsored byLABORATORY MEDICINE PRACTICE GUIDELINES Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Loralie J. Langman Committee Chair Department of Laboratory Medicine and Pathology Mayo Clinic

2018 American Academy of Pain Medicine

3. Functional Family Therapy (FFT) for Young People in Treatment for Non?opioid Drug Use: A Systematic Review Full Text available with Trip Pro

version of this article with your friends and colleagues. Copy URL Share a link Share on 1 The terms ‘use’, ‘abuse’ and ‘dependence’ are often used interchangeably and refer to an addiction stage of non‐medical drug usage. of the kind that persists beyond the experimentation phase is a severe problem worldwide ( ). Abuse of non‐opioid drugs such as cannabis, amphetamine and cocaine is strongly associated with a broad range of negative health implications such as traffic accidents, sexually transmitted (...) on the other hand may be equally effective. Family therapy encompasses a range of different interventions with varying theoretical sources, including behavioral and cognitive behavioral theory, structural and strategic family theory, and family systems theory ( ; ). Some reviews have suggested that these family‐based therapies are superior to individual‐based programs in reducing youth drug abuse ( ; ; ). Young people with persistent drug abuse have unique needs due to their particular cognitive

2015 Campbell Collaboration

4. Family Behavior Therapy (FBT) for Young People in Treatment for Non?opioid Drug Use: A Systematic Review Full Text available with Trip Pro

point to the fact that many research projects have empirically validated different kinds of treatment approaches for young drug users as effective (e.g. ; ; ; ). The current dilemma in the field of youth substance abuse treatment is that it is not clear what works best, as the research suggest that most interventions lead to reduced drug use. While there are some promising individual‐based cognitive, cognitive‐behavioral and motivational therapies ( ; ; ; ), family‐based approaches may also show (...) Family Behavior Therapy (FBT) for Young People in Treatment for Non?opioid Drug Use: A Systematic Review Family Behavior Therapy (FBT) for Young People in Treatment for Non‐opioid Drug Use: A Systematic Review - Lindstrøm - 2015 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Family Behavior Therapy (FBT) for Young People in Treatment

2015 Campbell Collaboration

5. Cognitive?Behavioural Therapies for Young People in Outpatient Treatment for Non?Opioid Drug Use: A Systematic Review Full Text available with Trip Pro

below to share a full-text version of this article with your friends and colleagues. Copy URL Share a link Share on 1 The terms use, abuse and dependence are used interchangeably throughout the review and refer to an addiction stage of non‐medical usage. that persists beyond curious experimentation is a severe problem worldwide ( ). Drugs such as cannabis, amphetamines, ecstasy and cocaine, referred to in this review as non‐opioids 2 Use of ketamine, nitrous oxide and inhalants, e.g. glue and petrol (...) Cognitive?Behavioural Therapies for Young People in Outpatient Treatment for Non?Opioid Drug Use: A Systematic Review Cognitive‐Behavioural Therapies for Young People in Outpatient Treatment for Non‐Opioid Drug Use: A Systematic Review - Filges - 2015 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Cognitive‐Behavioural Therapies

2015 Campbell Collaboration

6. Brief Strategic Family Therapy (BSFT) for Young People in Treatment for Non?Opioid Drug Use: A Systematic Review Full Text available with Trip Pro

different kinds of treatment approaches for young drug users as effective ( ; ; Williams, Chang & Addiction Centre Adolescent Research Group, 2000; ). The current dilemma in the field of substance abuse treatment for young people is that it is not clear what works best, with research suggesting that almost all interventions lead to reduced drug use. While there are some promising individually‐based cognitive and motivational therapies ( ; ; ; Galanter & Kleber, 2008), family‐based approaches may (...) psychosocial interventions for substance abuse and misuse in young offenders in locked facilities ( ). to young people age 11‐21 who are living with their families. This review focuses solely on non‐opioid drug use 8 Two Cochrane reviews have evaluated psychosocial treatments for treatment of opioid dependence ( ; Minozzi et al., 2010). and is one in a series of reviews on manual‐based family therapy interventions for young people in treatment for non‐opioid drug use 9 See the following Title Registrations

2013 Campbell Collaboration

7. Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy

to make recommendations. Other: Pharmacogenomic Testing pharmacogenomic drug response test provides personalized insights on a patient's predicted response to medications based on metabolism Other Names: Pillcheck Geneyouin Placebo Comparator: Control Pharmacist optimizing antidepressant therapy based on standard of care Other: Pharmacist Standard of Care Pharmacist providing standard of care as per usual practice Outcome Measures Go to Primary Outcome Measures : Treatment Satisfaction with Medicines (...) of uncertainty over the value of personalized medicine, recent studies show promising approaches for incorporating pharmacogenetics (PGx) data into routine patient care in order to reduce medication issues due to genetic factors. Over the last decades, clinical PGx research has made significant progress in defining which genetic variations are important for influencing inter-patient variability in drug response. Evidence-based consensus therapeutic guidelines for multiple drug-gene pairs are available

2018 Clinical Trials

8. A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-admin

venipuncture or inadequate venous access as determined by the investigator. Recent (within 6 months of first IMP dosing) drug or alcohol abuse as defined in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), Diagnostic Criteria for Drug and Alcohol Abuse. Subjects who drink more than 3 cups of coffee or other caffeine-containing products a day, or 5 cups of tea a day. Use of tobacco-containing or nicotine-containing products (including but not limited to cigarettes, pipes (...) A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-admin A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual

2017 Clinical Trials

9. Novel Synthetic Opioids in Counterfeit Pharmaceuticals and Other Illicit Street Drugs

Bulletin: Novel Synthetic Opioids in Counterfeit Pharmaceuticals and Other Illicit Street Drugs Canadian Centre on Substance Abuse • Centre canadien de lutte contre les toxicomanies Page 12 Pag e 12 1 U.S. Food and Drug Administration. (2016). Counterfeit Medicine. Retrieved June 2, 2016, from www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/CounterfeitMedicine/ 2 Canadian Community Epidemiology Network on Drug Use. (2014). CCENDU Drug Alert: Increasing Availability of Counterfeit (...) Novel Synthetic Opioids in Counterfeit Pharmaceuticals and Other Illicit Street Drugs www.ccsa.ca • www.cclt.ca CCENDU Bulletin, June 2016 Canadian Centre on Substance Abuse • Centre canadien de lutte contre les toxicomanies Page 1 CCENDU Bulletin Novel Synthetic Opioids in Counterfeit Pharmaceuticals and Other Illicit Street Drugs Summary ? Counterfeit pharmaceuticals are fake products manufactured illegally in clandestine labs. They are designed to look like legitimate pharmaceuticals. ? Sale

2016 Canadian Centre on Substance Abuse

10. Evaluation of tricuspid valve repair without annuloplasty ring in Intravenous drug abusers. (Abstract)

Evaluation of tricuspid valve repair without annuloplasty ring in Intravenous drug abusers. Tricuspid valve endocarditis among intravenous drug abusers is increasing in prevalence in modern societies. The increased risk of reinfection in such patients makes surgical reintervention a risky decision. Repair is preferred over replacement to minimize the presence of foreign material in a potentially infected field.A retrospective, observational, comparative, non-randomized study included all living (...) patients presenting with isolated tricuspid valve endocarditis due to IV drug abuse who had undergone tricuspid valve intervention in the form of repair or replacement. Two hundred twenty-three patients were operated on between January 2014 and January 2016; 128 patients underwent tricuspid valve replacement (replacement group n = 128), and 95 patients underwent tricuspid valve repair (repair group n = 95).Before hospital discharge, 87 patients of the repair group had mild TR, and eight patients had

2019 Annals of Thoracic Surgery

11. Comparison between intravenous morphine versus fentanyl in acute pain relief in drug abusers with acute limb traumatic injury. Full Text available with Trip Pro

Comparison between intravenous morphine versus fentanyl in acute pain relief in drug abusers with acute limb traumatic injury. Rapid and effective pain relief in acute traumatic limb injuries (ATLI) is one of the most important roles of emergency physicians. In these situations, opioid addiction is an important concern because of the dependency on opioids. The study aims to compare the effectiveness of intravenous (IV) fentanyl versus morphine in reducing pain in patients with opioid addiction (...) who suffered from ATLI.In this double-blind randomized clinical trial, 307 patients with ATLI, who presented to the emergency department (ED) from February 2016 to April 2016, were randomly divided into two groups. One group (152 patients) received 0.1 mg/kg IV morphine. The other group (155 patients) received 1 mcg/kg IV fentanyl. Patients' demographic data, pain score at specific intervals, vital signs, side effects, satisfaction and the need for rescue analgesia were recorded.Eight patients

2019 World journal of emergency medicine Controlled trial quality: uncertain

12. Abuse deterrence testing: A dose ratio escalation study examining naloxone coadministered with intravenous hydromorphone in non-treatment-seeking, opioid-dependent drug users. (Abstract)

Abuse deterrence testing: A dose ratio escalation study examining naloxone coadministered with intravenous hydromorphone in non-treatment-seeking, opioid-dependent drug users. To assess the reduction in intravenous (IV) abuse potential of hydromorphone from different dose ratio combinations with naloxone in opioid-dependent drug users.Randomized, blinded, dose ratio escalation study.Single center.Following conversion to a stable IV dose of hydromorphone, 12 non-treatment-seeking, opioid (...) associated with significant increases in SOWS and OOWS scores (p < 0.05). Compared with hydromoprophone/naloxone placebo, naloxone reduced the effects of hydromorphone on most measures, including Drug Liking VAS, the antagonism was greatest for the 4:1 and 2:1 ratios.This study was an ethical investigation of the abuse deterrence potential of four hydromorphone/naloxone dose ratios. The IV coadministration of commercially available IV solutions of hydromorphone and naloxone in 4:1 and 2:1 ratios had

2018 Journal of opioid management Controlled trial quality: uncertain

13. Bilateral Pneumothoraces: A Rare Complication of Septic Pulmonary Emboli in Intravenous Drug Abusers Full Text available with Trip Pro

Bilateral Pneumothoraces: A Rare Complication of Septic Pulmonary Emboli in Intravenous Drug Abusers BACKGROUND Right-sided infective endocarditis is a classic complication of intravenous drug abuse. Without timely bactericidal antibiotics, the disease process can progress to septic pulmonary emboli. Rarely, a pneumothorax can occur as a result of the emboli, and progressive persistent valvular disease may require a valve replacement. Tricuspid valve replacement has a high morbidity rate even (...) in stable patients. CASE REPORT We present a case of tricuspid valve replacement in a 39-year-old man with peripheral intravenous drug abuse who had bilateral pneumothoraces secondary to septic pulmonary emboli originating on large tricuspid valve infected vegetations. The patient died 21 days after the valve replacement. CONCLUSIONS Tricuspid valve replacement is an especially dangerous procedure in intravenous drug abusers who present with bilateral pneumothoraces and advanced cardiopulmonary

2018 The American journal of case reports

14. Mycobacterium mucogenicum Hand Infection in an Intravenous Drug Abuser Full Text available with Trip Pro

Mycobacterium mucogenicum Hand Infection in an Intravenous Drug Abuser Mycobacterium mucogenicum is a rapidly growing mycobacterium found ubiquitously in water sources. It has been reported to cause widespread infections with infection entry from wound or central venous catheters especially in immunocompromised patients. Diagnosis is made from blood cultures which may take at least a week. Management includes removal of the source or drainage of wound infections and combination antimicrobial (...) therapy.

2018 Case reports in infectious diseases

15. Infective Endocarditis Associated with Atrial Septal Defect in an Intravenous Drug Abuser: A Case Report Full Text available with Trip Pro

Infective Endocarditis Associated with Atrial Septal Defect in an Intravenous Drug Abuser: A Case Report Atrial septal defect (ASD) is a common congenital abnormality, which accounts for 20-40% of all the adult patients with congenital heart diseases. Due to the slow velocity of shunt flow, ASD has a negligible risk for infective endocarditis (IE). However, intravenous drug abuse (IVDA) is a potential cause for IE. IE remains a diagnostic and therapeutic challenge. Our case report demonstrates (...) , follow-up, along with rehabilitation measures, should be taken for patients with a history of drug abuse in order to prevent the risk of reinfection.

2018 Cureus

16. Impact of childhood sexual abuse on antiretroviral medication adherence, sexual risk behaviours and overall health among men who have sex with men

dysfunction, paraphilias and their relationship to childhood abuse in men who have sex with men. International Journal of Sexual Health 2009;(2):79-86. Springer A, Dushaj A, Azar M. The impact of DSM-IV mental disorders on adherence to combination antiretroviral therapy among adult persons living with HIV/AIDS: A systematic review. AIDS & Behavior 2012;16(8):2119-43. Suggested citation Rapid Response Service. Impact of childhood sexual abuse on antiretroviral medication adherence, sexual risk behaviours (...) Impact of childhood sexual abuse on antiretroviral medication adherence, sexual risk behaviours and overall health among men who have sex with men Impact of childhood sexual abuse on antiretroviral medication adherence, sexual risk behaviours and overall health among men who have sex with men | The Ontario HIV Treatment Network The Ontario HIV Treatment Network Impact of childhood sexual abuse on antiretroviral medication adherence, sexual risk behaviours and overall health among men who have

2016 Ontario HIV Treatment Network

17. Cannabidiol in a pharmaceutical formulation (Epidiolex; GWP42003-P) for Lennox-Gastaut syndrome in children and adults

Disease Gynaecology Womens Sexual Health and Benign Breast Disease Haematology and Blood Products Health Promotion and Protection including Screening Immunology and Allergy Infectious Disease and Immunisation Mens Health and Sexual Health Mental Health Drug Abuse and Learning Difficulties Musculoskeletal Neurology and Neurosurgery Other Paediatrics and Neonatology Pregnancy and Childbirth Radiology Imaging and Nuclear Medicine Rehabilitation and Disability Renal Disease and Urology Respiratory Disease (...) Cannabidiol in a pharmaceutical formulation (Epidiolex; GWP42003-P) for Lennox-Gastaut syndrome in children and adults Cannabidiol in a pharmaceutical formulation (Epidiolex; GWP42003-P) for Lennox-Gastaut syndrome in children and adults | Innovation Observatory toggle menu Menu Search View All Filter by Speciality Filter by Year Filter by Category This search function provides links to outputs produced by NIHR Innovation Observatory. These are briefing notes or reports on new or repurposed

2017 NIHR Innovation Observatory

18. Trauma-focused exposure therapy for chronic posttraumatic stress disorder in alcohol and drug dependent patients: A randomized controlled trial. Full Text available with Trip Pro

+ trauma-focused motivational enhancement session (mPE + MET-PTSD), or a health information-based control condition (HLS). All participants were multiply traumatized; the median number of reported traumas that satisfied DSM-IV Criterion A for PTSD was 8. Treatment consisted of 9-12 60-min individual therapy sessions plus substance abuse treatment-as-usual. Participants were assessed at baseline, end-of-treatment, and at 3- and 6-months posttreatment. Both the mPE and mPE + MET-PTSD conditions achieved (...) Trauma-focused exposure therapy for chronic posttraumatic stress disorder in alcohol and drug dependent patients: A randomized controlled trial. To test whether a modified version of prolonged exposure (mPE) can effectively treat posttraumatic stress disorder (PTSD) in individuals with co-occurring PTSD and substance dependence, an efficacy trial was conducted in which substance dependent treatment-seekers with PTSD (N = 126, male = 54.0%, White = 79.4%) were randomly assigned to mPE, mPE

2016 Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors Controlled trial quality: uncertain

19. Intravenous Opioid Drug Abuse as an Independent Risk Factor for Supraglottic Squamous Cell Carcinoma - A Case Control Study. (Abstract)

Intravenous Opioid Drug Abuse as an Independent Risk Factor for Supraglottic Squamous Cell Carcinoma - A Case Control Study. Intravenous opioid drug abuse (IVDA) was previously correlated with laryngeal cancer. However, discrimination of this correlation by anatomical subsites has not yet been described. In this study, we aim to further establish the association between IVDA and laryngeal squamous cell carcinoma (SCC) and to indicate the laryngeal subsites that are predisposed (...) was 10.846 (95% CI: 1.3-89.4).Intravenous opioid drug abuse represents an independent risk factor for SG-SCC. The pathogenesis should be investigated not just as a risk factor, as opioids are commonly used for pain management in oncologic patients.© 2017 John Wiley & Sons Ltd.

2017 Clinical Otolaryngology

20. Central nervous system fungal infection in a young male with a history of intravenous drug abuse and hepatitis C Full Text available with Trip Pro

Central nervous system fungal infection in a young male with a history of intravenous drug abuse and hepatitis C A young male, with a known history of hepatitis C and heroin abuse, was admitted to the emergency department with altered sensorium, left-sided weakness, and no meningeal signs. Initial computed tomography imaging showed hypodensity involving right basal ganglia with mass effect but no hemorrhage. Magnetic resonance imaging revealed multiple nonenhancing small foci of restricted (...) diffusion involving the right basal ganglia, T2 and FLAIR hyperintensity within the right basal ganglia, and internal capsule with mild surrounding edema. The patient was treated for encephalitis and atypical stroke given the history of intravenous drug abuse. Follow-up imaging showed worsening of the brain lesions, with involvement of the contralateral basal ganglia with necrosis and peripheral enhancement. Brain biopsy was ultimately performed and suggested infection with Aspergillus species

2017 Radiology Case Reports

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