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Intravenous Dextrose

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1. Intravenous Dextrose Drip versus Push for Adults Experiencing Hypoglycemia: Comparative Clinical Effectiveness

Intravenous Dextrose Drip versus Push for Adults Experiencing Hypoglycemia: Comparative Clinical Effectiveness Intravenous Dextrose Drip versus Push for Adults Experiencing Hypoglycemia: Comparative Clinical Effectiveness | CADTH.ca Find the information you need Intravenous Dextrose Drip versus Push for Adults Experiencing Hypoglycemia: Comparative Clinical Effectiveness Intravenous Dextrose Drip versus Push for Adults Experiencing Hypoglycemia: Comparative Clinical Effectiveness Last updated (...) : May 6, 2019 Project Number: RB1335-000 Product Line: Research Type: Drug Report Type: Summary of Abstracts Result type: Report Question What is the comparative clinical effectiveness and safety of dextrose 10% intravenous drip versus dextrose 50% intravenous push for adults experiencing acute hypoglycemia? Key Message No relevant literature was identified regarding the comparative clinical effectiveness and safety of dextrose 10% intravenous drip versus dextrose 50% intravenous push for adults

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

2. A randomized, double-blinded, controlled trial of the effects of fluid rate and/or presence of dextrose in intravenous fluids on the labor course of nulliparas (Abstract)

A randomized, double-blinded, controlled trial of the effects of fluid rate and/or presence of dextrose in intravenous fluids on the labor course of nulliparas Prolonged labor has been demonstrated to increase adverse maternal and neonatal outcome. A practice that may decrease the risk of prolonged labor is the modification of fluid intake during labor.Several studies demonstrated that increased hydration in labor as well as addition of dextrose-containing fluids may be associated (...) with a decrease in length of labor. The purpose of our study was to characterize whether high-dose intravenous fluids, standard-dose fluids with dextrose, or high-dose fluids with dextrose show a difference in the duration of labor in nulliparas.Nulliparous subjects with singletons who presented in active labor were randomized to 1 of 3 groups of intravenous fluids: 250 mL/h of normal saline, 125 mL/h of 5% dextrose in normal saline, or 250 mL/h of 2.5% dextrose in normal saline. The primary outcome was total

2017 EvidenceUpdates

3. The effects of intravenous dextrose 5%, Ringer's solution, and oral intake on the duration of labor stages in nulliparous women: a double-blind, randomized, controlled trial. (Abstract)

The effects of intravenous dextrose 5%, Ringer's solution, and oral intake on the duration of labor stages in nulliparous women: a double-blind, randomized, controlled trial. Childbirth consists of a three-stage period beginning with uterine contractions and ending in the expulsion of the placenta. The present study was conducted to compare the effects of Ringer's solution, dextrose solution 5%, and oral intake on the duration of total labor and labor stages (primary outcome) and the frequency (...) of oxytocin administration and prolonged labor (secondary outcome) in nulliparous women with spontaneous vaginal delivery.The present randomized clinical trial was conducted on 201 nulliparous women in labor assigned with a randomized block design to three groups, each receiving either Ringer's solution plus oral fluids, dextrose solution 5% solution plus oral fluids or oral fluids alone. The solutions were intravenously administered at a rate of 125 ml/h in the groups receiving the solutions

2018 The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Controlled trial quality: predicted high

4. Does perioperative intravenous dextrose reduce postoperative nausea and vomiting? A systematic review and meta-analysis Full Text available with Trip Pro

Does perioperative intravenous dextrose reduce postoperative nausea and vomiting? A systematic review and meta-analysis Perioperative dextrose-containing fluid administration has been used as a non-pharmacologic preventive measure against postoperative nausea and vomiting (PONV), a common and distressing complication of anesthesia. However, its efficacy remains unclear as previous studies reported inconsistent results. Our objective was to compare dextrose-containing fluid with non-dextrose (...) was poor due to high risks of selection and performance biases and substantial statistical heterogeneity. After subgroup analysis, the risk for PONV was reduced in patients who had undergone laparoscopic cholecystectomy, but not other surgeries, and the effects of dextrose on the risk for PONV did not differ according to the fluid volume administered.Perioperative intravenous (i.v.) dextrose did not reduce the risk for PONV. However, it did reduce the need for anti-emetics after general anesthesia

2018 Therapeutics and clinical risk management

5. Effect of intravenous dextrose administration on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: A randomised controlled trial. (Abstract)

Effect of intravenous dextrose administration on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: A randomised controlled trial. 28872580 2018 10 04 2018 10 04 1365-2346 34 10 2017 10 European journal of anaesthesiology Eur J Anaesthesiol Effect of intravenous dextrose administration on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: A randomised controlled trial. 705-707 10.1097/EJA.0000000000000643 Rao Vikram V From (...) the Department of Anaesthesia and Intensive Care, Post Graduate Institute of Medical Education and Research, Chandigarh, India (VR, IB, DJ, NB). Bala Indu I Jain Divya D Bharti Neerja N eng Letter Randomized Controlled Trial England Eur J Anaesthesiol 8411711 0265-0215 IY9XDZ35W2 Glucose IM Administration, Intravenous Adult Cholecystectomy, Laparoscopic adverse effects trends Double-Blind Method Female Glucose administration & dosage Humans Infusions, Intravenous Male Middle Aged Postoperative Care

2018 European Journal of Anaesthesiology Controlled trial quality: uncertain

6. Changes in Cytokine Levels After Dextrose Injection in Stage IV Knee Osteoarthritis

Changes in Cytokine Levels After Dextrose Injection in Stage IV Knee Osteoarthritis Changes in Cytokine Levels After Dextrose Injection in Stage IV Knee Osteoarthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Changes in Cytokine Levels After Dextrose Injection in Stage IV Knee Osteoarthritis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03400631 Recruitment Status : Recruiting First Posted : January 17, 2018 Last

2017 Clinical Trials

7. The effect of intravenous dextrose administration for prevention of post-operative nausea and vomiting after laparoscopic cholecystectomy: A double-blind, randomised controlled trial Full Text available with Trip Pro

The effect of intravenous dextrose administration for prevention of post-operative nausea and vomiting after laparoscopic cholecystectomy: A double-blind, randomised controlled trial Post-operative nausea and vomiting (PONV) is a common and distressing complication after laparoscopic cholecystectomy (LC). The aim of this study was to evaluate the effect of intravenous (IV) dextrose administration for the prophylaxis of PONV after LC.In a double-blind, randomised controlled trial, a total of 150 (...) : 0.28-0.64).Administration of IV dextrose before anaesthesia induction may be recommended as an effective, and safe method for the prophylaxis of PONV after LC.

2017 Indian journal of anaesthesia Controlled trial quality: predicted high

8. Effect of acetate Ringer(')ssolution with or without 5% dextrose administered intravenously to diarrheic calves. Full Text available with Trip Pro

to the isotonic saline (ISS), acetated Ringer's (AR) or acetated Ringer's with 5% dextrose (ARD) groups, with three calves assigned to each group. The calves received 80 ml/kg of their designated solution, at a flow rate of 20 ml/kg/hr. Infusion of ISS, AR and ARD were all found to be safe and effective in increasing plasma volume. Intravenous (IV) infusion of ISS resulted in the acidification secondary to dilution, while AR and ARD infusion inhibited acidification. In addition, prevention of catabolism (...) Effect of acetate Ringer(')ssolution with or without 5% dextrose administered intravenously to diarrheic calves. The objectives of this study were to evaluate the effects of intravenous acetate Ringer's solution, with or without dextrose, on diarrheic calves with either experimentally induced or spontaneous diarrhea. In the experimental model, diarrhea was induced in nine healthy calves by administering cold milk (below 4°C) twice a day for 2 days. The calves were randomly assigned

2017 The Journal of Veterinary Medical Science Controlled trial quality: uncertain

9. Clinical Impact of Rapid Intravenous Rehydration With Dextrose Serum in Children With Acute Gastroenteritis. (Abstract)

Clinical Impact of Rapid Intravenous Rehydration With Dextrose Serum in Children With Acute Gastroenteritis. We designed a study to compare rapid intravenous rehydration based on 0.9% normal saline (NS) or on NS + glucose 2.5% serum (SGS 2.5%) in patients with dehydration secondary to acute gastroenteritis. Our hypothesis is that the addition of glucose 2.5% serum (SGS 2.5%) to 0.9% saline solution could reduce the proportion of hospital admissions and return emergency visits in these patients

2017 Pediatric Emergency Care Controlled trial quality: uncertain

10. Dextrose versus no dextrose intravenous fluids for reduction of length of labor: a systematic review and meta analysis of randomized trials

Dextrose versus no dextrose intravenous fluids for reduction of length of labor: a systematic review and meta analysis of randomized trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2017 PROSPERO

11. Oral dextrose gel for the treatment of hypoglycaemia in newborn infants. (Abstract)

Oral dextrose gel for the treatment of hypoglycaemia in newborn infants. Neonatal hypoglycaemia, a common condition, can be associated with brain injury. It is frequently managed by providing infants with an alternative source of glucose, given enterally with formula or intravenously with dextrose solution. This often requires that mother and baby are cared for in separate environments and may inhibit breast feeding. Dextrose gel is simple and inexpensive and can be administered directly (...) hypoglycaemic event. We found no evidence of a difference between dextrose gel and placebo gel for major neurosensory disability at two-year follow-up (risk ratio (RR) 6.27, 95% confidence interval (CI) 0.77 to 51.03; one trial, n = 184; quality of evidence very low). Dextrose gel compared with placebo gel or no gel did not alter the need for intravenous treatment for hypoglycaemia (typical RR 0.78, 95% CI 0.46 to 1.32; two trials, 312 infants; quality of evidence very low). Infants treated with dextrose

2016 Cochrane

12. Perioperative Dextrose Infusion and Postoperative Nausea and Vomiting: A Meta-analysis of Randomized Trials (Abstract)

Perioperative Dextrose Infusion and Postoperative Nausea and Vomiting: A Meta-analysis of Randomized Trials Perioperative IV dextrose infusions have been investigated for their potential to reduce the risk of postoperative nausea and vomiting. In this meta-analysis, we investigated the use of an intraoperative or postoperative infusion of dextrose for the prevention of postoperative nausea and vomiting.Our group searched PubMed, Embase, Cochrane library, and Google Scholar for relevant (...) randomized controlled trials examining the use of perioperative IV dextrose for prevention of postoperative nausea and vomiting. The primary outcome was the incidence of postoperative nausea and vomiting (both in the postanesthesia care unit and within the first 24 h of surgery). Secondary outcomes included postoperative antiemetic administration and serum glucose level.Our search yielded a total of 10 randomized controlled trials (n = 987 patients) comparing the use of a perioperative dextrose infusion

2019 EvidenceUpdates

13. Intravenous Dextrose

Aka: Intravenous Dextrose From Related Chapters II. Indications by rapid bedside Child who fails to respond to III. Physiology Ill children deplete glycogen stores rapidly depresses neonatal myocardial function Effects of on brain Ischemic Neonatal brain May benefit from Mature Child brain Poor neurologic outcome with IV. Dosing See dosing by the rule of 50 below Dextrose 12.5% (D12.5W): 1:3 dilution of D50W in water Newborn: 0.5-1.0 g/kg (4-8 ml/kg) D12.5W IV or IO Dextrose 25% (D25W): 1:1 (...) Intravenous Dextrose Intravenous Dextrose Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Intravenous Dextrose Intravenous Dextrose

2018 FP Notebook

14. Oral Dextrose Gel Reduces the Need for Intravenous Dextrose Therapy in Neonatal Hypoglycemia Full Text available with Trip Pro

Oral Dextrose Gel Reduces the Need for Intravenous Dextrose Therapy in Neonatal Hypoglycemia Newborn infants with risk factors may require intravenous (IV) dextrose for asymptomatic hypoglycemia. Administration of IV dextrose and transfer to the neonatal intensive care unit (NICU) may interfere with parent-infant bonding.To study the effect of implementing dextrose gel supplement with feeds in late preterm/term infants affected by asymptomatic hypoglycemia on reducing IV dextrose therapy.A (...) retrospective study was conducted before and after dextrose gel use: 05/01/2014 to 10/31/2014 and 11/01/2014 to 04/30/2015, respectively. Asymptomatic hypoglycemic (blood glucose level <45 mg/dl) infants in the newborn nursery (NBN) were given a maximum of 3 doses of dextrose gel (200 mg/kg of 40% dextrose) along with feeds. Transfer to the NICU for IV dextrose was considered treatment failure.Dextrose gel with feeds increased the blood glucose level in 184/250 (74%) of asymptomatic hypoglycemic infants

2016 Biomedicine hub

15. Normal Saline and Dextrose 5% in Water Do Not Support Bacterial Growth 24 Hours After Being Spiked in the Perioperative Environment. (Abstract)

Normal Saline and Dextrose 5% in Water Do Not Support Bacterial Growth 24 Hours After Being Spiked in the Perioperative Environment. The Joint Commission requirement is that the US Pharmacopeia Chapter <797> is followed, which recommends that administration of compounded sterile preparations should begin no later than 1 hour after their preparation. We hypothesized that simply spiking the IV fluid in a nonsterile environment does not pose an increased risk of infection to the patient.Two 1000 (...) -mL bags of IV fluid (normal saline and dextrose 5% in water) were spiked and hung in 5 busy perioperative locations, once a week for a 13-week period. A 10-mL sample was drawn from each bag of IV fluid at time zero and 24 hours resulting in 260 samples in total. All samples were inoculated in 2 separate growth media (sheep's blood agar and thioglycollate broth). The primary outcome was growth versus no growth in any of the specimens. If any growth was noted, the sample was marked as positive

2019 Anesthesia and Analgesia

16. Incorporating dextrose gel and feeding in the treatment of neonatal hypoglycaemia. (Abstract)

Incorporating dextrose gel and feeding in the treatment of neonatal hypoglycaemia. To determine the impact of incorporating dextrose gel in the treatment of neonatal hypoglycaemia (NH) and the role of feeding type in NH outcomes.We conducted a retrospective analysis of 2688 infants >35 weeks' gestation who were screened for NH before and after implementation of a clinical guideline for NH evaluation and treatment. We analysed the proportion of infants who required intravenous dextrose for NH (...) before and after guideline implementation, the change in blood glucose concentrations with gel by feeding type and the odds of successful NH treatment with gel and feeding by feeding type.Following implementation of the guideline, a lower proportion of infants required intravenous dextrose for NH treatment (8.6% (60 infants) before guideline vs. 5.6% (112 infants) after guideline (p=0.007)). The median rise in blood glucose concentration with gel administration in the entire cohort was 0.61 mmol/L

2019 Archives of Disease in Childhood. Fetal and Neonatal Edition

17. Double-blind, randomized crossover study of intravenous infusion of magnesium sulfate versus 5% dextrose on depressive symptoms in adults with treatment-resistant depression. Full Text available with Trip Pro

Double-blind, randomized crossover study of intravenous infusion of magnesium sulfate versus 5% dextrose on depressive symptoms in adults with treatment-resistant depression. Treatment-resistant depression patients are more likely to suffer from comorbid physical and mental disorders, experience marked and protracted functional impairment, and incur higher health-care costs than non-affected individuals. Magnesium sulfate is a treatment option that may offer great potential for patients (...) with treatment-resistant depression based on prior work in animals and humans.Twelve subjects with mild or moderate treatment-resistant depression were randomized into a double-blind crossover trial to receive an infusion of 4 g of magnesium sulfate in 5% dextrose or placebo infusion of 5% dextrose with a 5-day washout in between the 8-day intervention period. Subjects were assessed before and after the intervention for serum and urine magnesium, lipid panel, the Hamilton Rating Scale for Depression

2016 Psychiatry and clinical neurosciences Controlled trial quality: uncertain

18. Is perioperative administration of 5% dextrose effective in reducing the incidence of PONV in laparoscopic cholecystectomy?: A randomized control trial. (Abstract)

I to II undergoing laparoscopic cholecystectomy were enrolled in this study.Patients were randomized into two groups [normal saline (NS) group and 5% dextrose (D) group]. Both the groups received Ringer acetate (Sterofundin ISO) intravenously as a maintenance fluid during intraoperative period. Besides this, patients of group NS received 250ml of 0.9% normal saline and patients of group D received 5% dextrose @ 100ml/h started at the time when gall bladder was taken out. It was continued (...) Is perioperative administration of 5% dextrose effective in reducing the incidence of PONV in laparoscopic cholecystectomy?: A randomized control trial. To compare the incidence of postoperative nausea and vomiting (PONV) during perioperative administration of 5% dextrose and normal saline in laparoscopic cholecystectomy.Prospective, randomized, double-blind trial.Operating rooms in a tertiary care hospital of Northern India.One hundred patients with American Society of Anesthesiologists status

2018 Journal of clinical anesthesia Controlled trial quality: uncertain

19. Impact of dextrose dose on hypoglycemia development following treatment of hyperkalemia Full Text available with Trip Pro

Impact of dextrose dose on hypoglycemia development following treatment of hyperkalemia Hyperkalemia is an electrolyte abnormality that may cause ventricular dysrhythmias and cardiac arrest. The presence of hyperkalemia may necessitate prompt treatment via intravenous insulin and dextrose. One notable complication of this therapy is the development of hypoglycemia. Previous trials have examined the impact of altering the insulin dose administered on hypoglycemia development; no trials to date (...) however, have examined the impact of altering the dextrose dose.This was a multicenter, retrospective, matched cohort study of patients who received intravenous insulin and dextrose for reversal of hyperkalemia. Patients received either 25 g or 50 g of dextrose in addition to 10 units of insulin. Study populations were matched based on preexisting rates of acute kidney injury, end-stage renal disease, and diabetes mellitus. Blood glucose levels were measured at 60 and 240 min following treatment.A

2018 Therapeutic advances in drug safety

20. Study of Early Enteral Dextrose in Sepsis

and in-hospital mortality. Condition or disease Intervention/treatment Phase Sepsis Other: Enteral Dextrose Infusion Other: Free Water Infusion Not Applicable Detailed Description: The central objective of this research project is to determine how early caloric support impacts inflammatory and metabolic outcomes in the acute phase of sepsis. Preliminary data from our mouse models suggest that provision of dextrose via an intravenous route, even at low levels early in the course of sepsis, markedly impairs (...) Study of Early Enteral Dextrose in Sepsis Study of Early Enteral Dextrose in Sepsis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of Early Enteral Dextrose in Sepsis (SEEDS) The safety

2018 Clinical Trials

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