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Intrauterine Growth Retardation

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162. Cytomegalovirus Infection in Pregnancy

, petechiae, jaundice, chorioretinitis, thrombocytopenia and anemia, and long-term sequelae consist of sensorineural hearing loss, mental retardation, delay of psychomotor development, and visual impairment. These guidelines provide a framework for diagnosis and management of suspected CMV infections. Evidence Medline was searched for articles published in English from 1966 to 2009, using appropriate controlled vocabulary (congenital CMV infection) and key words (intrauterine growth restriction (...) or . Click to view the full text on ScienceDirect. Figures Figure Algorithm for prenatal diagnosis of congenital CMV Abstract Objectives To review the principles of prenatal diagnosis of congenital cytomegalovirus (CMV) infection and to describe the outcomes of the affected pregnancies. Outcomes Effective management of fetal infection following primary and secondary maternal CMV infection during pregnancy. Neonatal signs include intrauterine growth restriction (IUGR), microcephaly, hepatosplenomegaly

2018 Society of Obstetricians and Gynaecologists of Canada

164. ESC/ESH Management of Arterial Hypertension Full Text available with Trip Pro

Vascular endothelial growth factor WUCH White-coat uncontrolled hypertension 1 Preamble Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in selecting the best management strategies for an individual patient with a given condition. Guidelines and their recommendations should facilitate decision making of health professionals in their daily practice. However, the final decisions concerning an individual patient must be made by the responsible health

2018 European Society of Cardiology

165. Budesonide (Jorveza) - to treat adults with eosinophilic oesophagitis

of these studies resemble those which are already known from other glucocorticoids (e.g. foetal deaths, intrauterine growth retardation, and skeletal abnormalities). Budesonide for oral use has already been licensed in Europe for other gastrointestinal indications with daily doses above the maximum recommended dose for Jorveza (9 mg versus 2 mg). Therefore no unknown risk will be associated with a lower daily dose in pregnant women. The information provided in section 4.6 of the SmPC is in line

2018 European Medicines Agency - EPARs

166. Glibenclamide (Amglidia) - Diabetes Mellitus

performance liquid chromatography ICH International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use iDEND intermediate DEND IDDM insulin dependent diabetes mellitus IR Infrared IUGR Intrauterine growth restriction KATP channel ATP-sensitive potassium channel KCNJ11 gene encoding Kir6.2 Kir6.2 Potassium inward rectifier 6.2 MRI Magnetic resonance imaging NEJM The New England Journal of Medicine ND Neonatal Diabetes NDM Neonatal Diabetes mellitus NSH (...) to those proposed for marketing and were packed in the primary packaging proposed for marketing. Samples were tested using the same analytical methods as at release. The analytical procedures used are stability indicating. No significant changes have been observed under long term and accelerated conditions. In addition, one batch was exposed to light as defined in the ICH Guideline on Photostability Testing of New Drug Substances and Products. This study showed that unknown impurities were growing

2018 European Medicines Agency - EPARs

168. Management of Infertility

infertility, there is no difference between the oral agents of letrozole and anastrozole for the outcome of ectopic pregnancy (low SOE), but evidence is insufficient for other outcomes of interest. There was also no difference between differing adjunct treatments used in combination with oral agents and intrauterine insemination (IUI) for the outcomes of live birth, miscarriage, and ovarian hyperstimulation syndrome (OHSS) (low SOE for all outcomes). Time to pregnancy was shorter with immediate in vitro (...) approximately 6 percent of married women aged 15-44 in the 2006-2010 National Survey of Family Growth (the most recent available data). 2 In one population-based study, approximately 10 percent of pregnant women reported receiving infertility treatment, with 29 percent of these women using fertility-enhancing medications; 21 percent using assisted reproductive technology (ART), including in vitro fertilization (IVF); 15 percent using artificial insemination with fertility-enhancing drugs; and 23 percent

2019 Effective Health Care Program (AHRQ)

169. Emergency management of adrenal insufficiency in children: advocating for treatment options in outpatient and field settings

CDKN1C IMAGe syndrome (intrauterine growth retardation, metaphyseal dysplasia, genital anomalies) Triple A or Allgrove AAAS Achalasia, alacrima Isolated familial glucocorticoid deficiency (FGD) MC2R, MRAP Tall stature, normal mineralocorticoid production FGD–DNA repair defect MCM4 NK-cell defect, short stature, recurrent viral infections, microcephaly, chromosomal breakage Glucocorticoid resistance GCCR Mineralocorticoid/androgen excess Metabolic diseases Adrenoleuk odystrophy ABCD1 Neurologic (...) deterioration Zellweger PEX Cerebrohepatorenal syndrome Smith-Lemli-Opitz DHCR7 46,XY sex reversal, polydactyly, mental retardation W olman LIPA Hepatomegaly Mitochondrial disease K earns-Sayre Ophthalmoplegia, myopathy secondary: hypothalamus Holoprosencephaly GLI2, FGF8 CRH deficiency Maternal hypercortisolemia secondary: pituitary/hypothalamus Isolated ACTH deficiency TPIT Multiple anterior pituitary hormone deficiencies due to pituitary aplasia/hypoplasia HESX1 Septo-optic dysplasia (optic nerve

2019 Pediatric Endocrine Society

172. Incorporating Recognition and Management of Perinatal Depression Into Pediatric Practice

complications, which compound the risk for perinatal depression. Anxiety symptoms in pregnancy are associated with preterm birth, low birth weight infants, increased rate of cesarean delivery, reduced duration of breastfeeding, and increased maternal health care use within 2 weeks of delivery. Maternal anxiety has also been connected to altered infant immune system function, altered patterns of infant gastrointestinal microorganism growth, and some limited research suggests that neural structures (...) . Long-term impact of insecure attachment extends to preschool and older children with anxiety, behavior problems, poor peer relationships, school problems, and depression. Such behaviors may even serve to worsen a parent’s sense of worthlessness, rejection, and depression. Effect on the Child In the prenatal period, maternal stress and depression negatively affect fetal growth and development. Stress hormones, such as cortisol, are chronically elevated in states of generalized anxiety and depression

2019 American Academy of Pediatrics

173. Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation

, 2010 Sponsor: Pfizer Information provided by: Pfizer Study Details Study Description Go to Brief Summary: To evaluate the effect of continuous and intermittent administration of Genotonorm on stature in short prepubertal children with intra-uterine growth retardation Condition or disease Intervention/treatment Phase Growth Disorders Intrauterine Growth Retardation Drug: Genotonorm Phase 3 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual (...) Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2010 Clinical Trials

174. Biological medicine and pregnancy: Clinical recommendations

foreligger ingen information, amning må derfor frarådes. Øvrige monoklonale antistoffer: Der er ikke rapporteret cases ved brug under graviditet og amning. Stofferne frarådes til brug under graviditet. Stofferne gennemgås kort. Bevacimab Virkningsmekanisme: monlonale antistoffer målrettet mod VEGF-receptor (Vacular Endothelian Growth Factor receptor), som regulerer det kardiovaskulære system. I dyreforsøg ses påvirkning af corpus luteum med fører spontan abort. Angiogensen påvirkes i sådan en grad (...) graviditet Ipilimumab Virkningsmekanisme: blokerer inhibitionen af T-celle aktivering, hvilket medfører en kraftig aktivering af T-celle respons. Indikationer: inoperabel og metastatisk melanom Der er ikke rapporteret brug under graviditet. I dyreforsøg hos gravide aber fandt man dosis- afhængig øget spontan abort, intrauterin fosterdød og præmatur fødsel 11 . Mortalitetsraten var øget i afkommet, samt en mulig association med urogenitiale misdannelser. FDA kategoriseret til C Amning I en case report fra

2018 Nordic Federation of Societies of Obstetrics and Gynecology

177. Low-Dose Aspirin Use During Pregnancy

, Nicolaides K, Giguere Y, Vainio M, Bakthi A, et al. Early administration of low-dose aspirin forthepreventionofpretermandtermpreeclampsia:asys- tematic review and meta-analysis. Fetal Diagn Ther 2012; 31:141–6. 45. Wallenburg HC, Rotmans N. Prevention of recurrent idi- opathic fetal growth retardation by low-dose aspirin and dipyridamole. Am J Obstet Gynecol 1987;157:1230–5. 46. Leitich H, Egarter C, Husslein P, Kaider A, Schemper M. A meta-analysis of low dose aspirin for the prevention of intrauterine (...) , and the World Institute of Pain. Reg Anesth Pain Med 2015;40:182–212. 37. Wallenburg HC, Dekker GA, Makovitz JW, Rotmans P. Low-dose aspirin prevents pregnancy-induced hyperten- sion and pre-eclampsia in angiotensin-sensitive primigra- vidae. Lancet 1986;1:1–3. 38. Low-dose aspirin in prevention and treatment of intrauter- ine growth retardation and pregnancy-induced hyperten- sion.Italianstudyofaspirininpregnancy.Lancet1993;341: 396–400. 39. RolnikDL,WrightD,PoonLC,O’GormanN,SyngelakiA, de Paco Matallana C

2018 American College of Obstetricians and Gynecologists

178. Pregnancy and Graves' disease: opt for treatments posing the lowest maternal and fetal risks

controlled hyperthyroidism exposes the woman to an increased risk of pre-eclampsia, i.e. high blood pressure and complications, as well as heart failure. This also exposes the unborn child to an increased risk of intrauterine growth retardation, fetal death and premature birth, hyperthyroidism, and mental retardation. Surgery in pregnancy carries a number of risks and is reserved for situations where a synthetic antithyroid is not desirable. Radioactive iodine should be ruled out as a treatment

2017 Prescrire

179. CRACKCast E178 – Co-Morbird Medical Emergencies During Pregnancy

and for the puerperium. [1] Describe the treatment of asthma exacerbation during pregnancy. What are the potential side effects of systemic glucocorticoids? Very common problem in pregnancy; associated with maternal and fetal morbidity. Controlling asthma during pregnancy leads to less intrauterine growth retardation and fewer adverse perinatal outcomes. It has been well documented that asthma may worsen, improve, or remain the same during pregnancy. Remember that a compensated respiratory alkalosis is normal

2018 CandiEM

180. Investigation and management of Transient Leukaemia of Down Syndrome Full Text available with Trip Pro

underestimate the prevalence of disease as, in our experience, the blast % often falls rapidly after birth and we recommend blast count assessment as soon as possible after birth to prevent delay in diagnosis of clinically relevant and life‐threatening cases of TL‐DS. Care should also be taken in neonates with intrauterine growth restriction (IUGR) or other history of placental insufficiency (e.g. maternal hypertension, pre‐eclampsia or diabetes mellitus) as these babies may have lower blast counts despite (...) , chest X‐ray, echocardiogram and abdominal ultrasound (Grade 1B). Any neonate with a blast percentage >10% and/or clinical features suggestive of TL‐DS should be discussed urgently with the regional Paediatric Oncology Principal Treatment Centre and a peripheral blood sample sent for GATA1 mutation analysis (Grade 1A). Any child who did not have a peripheral blood blast cell percentage performed in the first 3 days of life or in whom there was significant intra‐uterine growth retardation (when blast

2018 British Committee for Standards in Haematology

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