How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,452 results for

Intrauterine Growth Retardation

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Incorporating Recognition and Management of Perinatal Depression Into Pediatric Practice

complications, which compound the risk for perinatal depression. Anxiety symptoms in pregnancy are associated with preterm birth, low birth weight infants, increased rate of cesarean delivery, reduced duration of breastfeeding, and increased maternal health care use within 2 weeks of delivery. Maternal anxiety has also been connected to altered infant immune system function, altered patterns of infant gastrointestinal microorganism growth, and some limited research suggests that neural structures (...) . Long-term impact of insecure attachment extends to preschool and older children with anxiety, behavior problems, poor peer relationships, school problems, and depression. Such behaviors may even serve to worsen a parent’s sense of worthlessness, rejection, and depression. Effect on the Child In the prenatal period, maternal stress and depression negatively affect fetal growth and development. Stress hormones, such as cortisol, are chronically elevated in states of generalized anxiety and depression

2019 American Academy of Pediatrics

182. Emergency management of adrenal insufficiency in children: advocating for treatment options in outpatient and field settings

CDKN1C IMAGe syndrome (intrauterine growth retardation, metaphyseal dysplasia, genital anomalies) Triple A or Allgrove AAAS Achalasia, alacrima Isolated familial glucocorticoid deficiency (FGD) MC2R, MRAP Tall stature, normal mineralocorticoid production FGD–DNA repair defect MCM4 NK-cell defect, short stature, recurrent viral infections, microcephaly, chromosomal breakage Glucocorticoid resistance GCCR Mineralocorticoid/androgen excess Metabolic diseases Adrenoleuk odystrophy ABCD1 Neurologic (...) deterioration Zellweger PEX Cerebrohepatorenal syndrome Smith-Lemli-Opitz DHCR7 46,XY sex reversal, polydactyly, mental retardation W olman LIPA Hepatomegaly Mitochondrial disease K earns-Sayre Ophthalmoplegia, myopathy secondary: hypothalamus Holoprosencephaly GLI2, FGF8 CRH deficiency Maternal hypercortisolemia secondary: pituitary/hypothalamus Isolated ACTH deficiency TPIT Multiple anterior pituitary hormone deficiencies due to pituitary aplasia/hypoplasia HESX1 Septo-optic dysplasia (optic nerve

2019 Pediatric Endocrine Society

184. Management of Infertility

infertility, there is no difference between the oral agents of letrozole and anastrozole for the outcome of ectopic pregnancy (low SOE), but evidence is insufficient for other outcomes of interest. There was also no difference between differing adjunct treatments used in combination with oral agents and intrauterine insemination (IUI) for the outcomes of live birth, miscarriage, and ovarian hyperstimulation syndrome (OHSS) (low SOE for all outcomes). Time to pregnancy was shorter with immediate in vitro (...) approximately 6 percent of married women aged 15-44 in the 2006-2010 National Survey of Family Growth (the most recent available data). 2 In one population-based study, approximately 10 percent of pregnant women reported receiving infertility treatment, with 29 percent of these women using fertility-enhancing medications; 21 percent using assisted reproductive technology (ART), including in vitro fertilization (IVF); 15 percent using artificial insemination with fertility-enhancing drugs; and 23 percent

2019 Effective Health Care Program (AHRQ)

187. Glibenclamide (Amglidia) - Diabetes Mellitus

performance liquid chromatography ICH International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use iDEND intermediate DEND IDDM insulin dependent diabetes mellitus IR Infrared IUGR Intrauterine growth restriction KATP channel ATP-sensitive potassium channel KCNJ11 gene encoding Kir6.2 Kir6.2 Potassium inward rectifier 6.2 MRI Magnetic resonance imaging NEJM The New England Journal of Medicine ND Neonatal Diabetes NDM Neonatal Diabetes mellitus NSH

2018 European Medicines Agency - EPARs

188. Severe insulin resistance and intrauterine growth deficiency associated with haploinsufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism. (PubMed)

Severe insulin resistance and intrauterine growth deficiency associated with haploinsufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism. Digenic causes of human disease are rarely reported. Insulin via its receptor, which is encoded by INSR, plays a key role in both metabolic and growth signaling pathways. Heterozygous INSR mutations are the most common cause of monogenic insulin resistance. However, growth retardation is only reported (...) with homozygous or compound heterozygous mutations. We describe a novel translocation [t(7,19)(p15.2;p13.2)] cosegregating with insulin resistance and pre- and postnatal growth deficiency. Chromosome translocations present a unique opportunity to identify modifying loci; therefore, our objective was to determine the mutational mechanism resulting in this complex phenotype.Breakpoint mapping was performed by fluorescence in situ hybridization (FISH) on patient chromosomes. Sequencing and gene expression

Full Text available with Trip Pro

2009 Diabetes

189. Pregnancy and Graves' disease: opt for treatments posing the lowest maternal and fetal risks

controlled hyperthyroidism exposes the woman to an increased risk of pre-eclampsia, i.e. high blood pressure and complications, as well as heart failure. This also exposes the unborn child to an increased risk of intrauterine growth retardation, fetal death and premature birth, hyperthyroidism, and mental retardation. Surgery in pregnancy carries a number of risks and is reserved for situations where a synthetic antithyroid is not desirable. Radioactive iodine should be ruled out as a treatment

2017 Prescrire

191. Low-Dose Aspirin Use During Pregnancy

, Nicolaides K, Giguere Y, Vainio M, Bakthi A, et al. Early administration of low-dose aspirin forthepreventionofpretermandtermpreeclampsia:asys- tematic review and meta-analysis. Fetal Diagn Ther 2012; 31:141–6. 45. Wallenburg HC, Rotmans N. Prevention of recurrent idi- opathic fetal growth retardation by low-dose aspirin and dipyridamole. Am J Obstet Gynecol 1987;157:1230–5. 46. Leitich H, Egarter C, Husslein P, Kaider A, Schemper M. A meta-analysis of low dose aspirin for the prevention of intrauterine (...) , and the World Institute of Pain. Reg Anesth Pain Med 2015;40:182–212. 37. Wallenburg HC, Dekker GA, Makovitz JW, Rotmans P. Low-dose aspirin prevents pregnancy-induced hyperten- sion and pre-eclampsia in angiotensin-sensitive primigra- vidae. Lancet 1986;1:1–3. 38. Low-dose aspirin in prevention and treatment of intrauter- ine growth retardation and pregnancy-induced hyperten- sion.Italianstudyofaspirininpregnancy.Lancet1993;341: 396–400. 39. RolnikDL,WrightD,PoonLC,O’GormanN,SyngelakiA, de Paco Matallana C

2018 American College of Obstetricians and Gynecologists

192. Investigation and management of Transient Leukaemia of Down Syndrome

underestimate the prevalence of disease as, in our experience, the blast % often falls rapidly after birth and we recommend blast count assessment as soon as possible after birth to prevent delay in diagnosis of clinically relevant and life‐threatening cases of TL‐DS. Care should also be taken in neonates with intrauterine growth restriction (IUGR) or other history of placental insufficiency (e.g. maternal hypertension, pre‐eclampsia or diabetes mellitus) as these babies may have lower blast counts despite (...) , chest X‐ray, echocardiogram and abdominal ultrasound (Grade 1B). Any neonate with a blast percentage >10% and/or clinical features suggestive of TL‐DS should be discussed urgently with the regional Paediatric Oncology Principal Treatment Centre and a peripheral blood sample sent for GATA1 mutation analysis (Grade 1A). Any child who did not have a peripheral blood blast cell percentage performed in the first 3 days of life or in whom there was significant intra‐uterine growth retardation (when blast

Full Text available with Trip Pro

2018 British Committee for Standards in Haematology

193. Low-Dose Aspirin Use During Pregnancy

, Nicolaides K, Giguere Y, Vainio M, Bakthi A, et al. Early administration of low-dose aspirin forthepreventionofpretermandtermpreeclampsia:asys- tematic review and meta-analysis. Fetal Diagn Ther 2012; 31:141–6. 45. Wallenburg HC, Rotmans N. Prevention of recurrent idi- opathic fetal growth retardation by low-dose aspirin and dipyridamole. Am J Obstet Gynecol 1987;157:1230–5. 46. Leitich H, Egarter C, Husslein P, Kaider A, Schemper M. A meta-analysis of low dose aspirin for the prevention of intrauterine (...) , and the World Institute of Pain. Reg Anesth Pain Med 2015;40:182–212. 37. Wallenburg HC, Dekker GA, Makovitz JW, Rotmans P. Low-dose aspirin prevents pregnancy-induced hyperten- sion and pre-eclampsia in angiotensin-sensitive primigra- vidae. Lancet 1986;1:1–3. 38. Low-dose aspirin in prevention and treatment of intrauter- ine growth retardation and pregnancy-induced hyperten- sion.Italianstudyofaspirininpregnancy.Lancet1993;341: 396–400. 39. RolnikDL,WrightD,PoonLC,O’GormanN,SyngelakiA, de Paco Matallana C

2018 American College of Obstetricians and Gynecologists

194. CRACKCast E178 – Co-Morbird Medical Emergencies During Pregnancy

and for the puerperium. [1] Describe the treatment of asthma exacerbation during pregnancy. What are the potential side effects of systemic glucocorticoids? Very common problem in pregnancy; associated with maternal and fetal morbidity. Controlling asthma during pregnancy leads to less intrauterine growth retardation and fewer adverse perinatal outcomes. It has been well documented that asthma may worsen, improve, or remain the same during pregnancy. Remember that a compensated respiratory alkalosis is normal

2018 CandiEM

195. CRACKCast E177 – Acute Complications of Pregnancy

or intracranial bleeding, renal insufficiency, and death. Neonatal complications: placental infarcts, intrauterine growth retardation, premature delivery 13) Describe the management of eclampsia and severe pre-eclampsia. The patient who has severe preeclampsia should have an IV line and fetal monitoring initiated. Blood testing should include complete blood cell count, renal function studies, liver function tests, platelet count, and coagulation profile. A baseline magnesium level should also be determined (...) trimester bleeding. Thinking outside in: Other pelvic source – rectal vs. urinary External/internal labia Introitus source Vaginal wall / vault Cervix Intrauterine Miscarriage Implantation bleeding Molar pregnancy Or worst first: Ectopic Miscarriage Molar pregnancy Cervical lesion (cancer) Coagulopathy 2) List 5 RFs for miscarriage. What percentage of women who have bleeding miscarry? Increased maternal age (especially > 40 yrs) Increasing parental age Increased parity Hx of prior miscarriage Multiple

2018 CandiEM

196. Management of specific situations in polycythaemia vera and secondary erythrocytosis

of obstetric complications, such as fetal loss throughout all trimesters, intra‐uterine growth retardation, prematurity, maternal thromboembolism and haemorrhage. Previously significant fetal loss and maternal morbidity was seen, but a recent prospective study of pregnancy outcomes in MPNs showed better outcomes. There were no maternal deaths or thrombotic events (Alimam et al , ). This improvement in pregnancy outcomes is probably partly due to a more protocol‐based management and a multidisciplinary (...) pregnancies should be identified (Table ). These are patients with previous arterial or venous thrombosis or haemorrhage attributed to PV, previous pregnancy complications (>3 first trimester losses, >1 s or third trimester loss, birth weight <5th centile for gestation, intrauterine death or stillbirth, pre‐eclampsia), extreme thrombocytosis before or during pregnancy, diabetes mellitus or hypertension requiring pharmacological treatment. Table 1. Management of risk factors during pregnancy During

Full Text available with Trip Pro

2018 British Committee for Standards in Haematology

197. Biological medicine and pregnancy: Clinical recommendations

foreligger ingen information, amning må derfor frarådes. Øvrige monoklonale antistoffer: Der er ikke rapporteret cases ved brug under graviditet og amning. Stofferne frarådes til brug under graviditet. Stofferne gennemgås kort. Bevacimab Virkningsmekanisme: monlonale antistoffer målrettet mod VEGF-receptor (Vacular Endothelian Growth Factor receptor), som regulerer det kardiovaskulære system. I dyreforsøg ses påvirkning af corpus luteum med fører spontan abort. Angiogensen påvirkes i sådan en grad (...) graviditet Ipilimumab Virkningsmekanisme: blokerer inhibitionen af T-celle aktivering, hvilket medfører en kraftig aktivering af T-celle respons. Indikationer: inoperabel og metastatisk melanom Der er ikke rapporteret brug under graviditet. I dyreforsøg hos gravide aber fandt man dosis- afhængig øget spontan abort, intrauterin fosterdød og præmatur fødsel 11 . Mortalitetsraten var øget i afkommet, samt en mulig association med urogenitiale misdannelser. FDA kategoriseret til C Amning I en case report fra

2018 Nordic Federation of Societies of Obstetrics and Gynecology

198. Guidelines for the Investigation and Management of Transient Leukaemia of Down Syndrome

should also be taken in neonates with intrauterine growth restriction (IUGR) or other history of placental insufficiency (e.g. maternal hypertension, pre-eclampsia or diabetes mellitus) as these babies may have lower blast counts despite large mutant GATA1 clones. Clinical features of TL-DS From their origin in the fetal liver, megakaryoblastic TL-DS cells can spread locally, spill into the peripheral blood and infiltrate throughout the liver as well as distant tissues. This usually manifests (...) with the regional Paediatric Oncology Principal Treatment Centre and a peripheral blood sample sent for GATA1 mutation analysis (Grade 1A). • Any child who did not have a peripheral blood blast cell percentage performed in the first 3 days of life or in whom there was significant intra-uterine growth retardation (when blast counts may be suppressed) should be considered to be still at risk of clinical problems of TL-DS in the first 4-8 weeks of life and should be monitored accordingly. GATA1 mutation analysis

2018 British Association of Perinatal Medicine

199. Management of Hypertension (5th Edition)

creatinine = 90 micromol/l or oliguria. iii. Liver disease: raised transaminases and / or severe right upper quadrant or epigastric pain. iv . Neurological problems: convulsions (eclampsia), hyperreflexia with clonus or severe headaches, persistent visual disturbances (scotoma). v. Haematological disturbances: thrombocytopenia, coagulopathy, haemolysis. vi. Fetal growth restriction. This is followed by normalization of the BP by three months postpartum. Oedema is no longer part of the definition (...) been shown to lead to fetal growth restriction. The use of ARBs, ACEIs and thiazide diuretics are associated with fetal anomaly 243 and are therefore contraindicated in pregnancy. It should be noted that the treatment of hypertension in pregnancy is solely for maternal safety. It does not reduce the risk of development of preeclampsia or perinatal mortality, nor improve fetal growth. 243 Pregnant women with uncomplicated chronic hypertension should have their BP kept lower than 150/100 mmHg

2018 Ministry of Health, Malaysia

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>