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21. Deceased organ and tissue donation after medical assistance in dying and other conscious and competent donors: guidance for policy

the options, ask questions and plan accordingly. Patients and their families should be provided with standardized information resources, such as online material or pamphlets, to help guide responses to donation inquiries. The decision to proceed with MAiD or WLSM must precede discussions about donation. Consent The patient must have the ability to provide first-person consent to MAiD or WLSM as well as to organ and tissue donation. Physicians, MAiD assessors, and WLSM or MAiD providers should be cognizant (...) article at CMAJ Podcasts: author interview at KEY POINTS • First-person consent for organ donation after medical assistance in dying (MAiD) or withdrawal of life-sustaining measures (WLSM) should be an option in jurisdictions that allow MAiD or WLSM and donation after circulatory determination of death. • The most important ethical concern — that the decision for MAiD or WLSM is being driven by a desire

2019 CPG Infobase

22. Public health guidance on prevention and control of blood-borne viruses in prison settings

was designed to answer the following questions: ? Which prevention, care and treatment interventions for BBVs are effective in prison settings? ? Which service models for prevention, care and/or treatment of BBVs are effective in prison settings? ? Which prevention, care and/or treatment interventions aimed at control of HIV are cost-effective in prison settings? ? Which service models for prevention, care and/or treatment of BBVs are cost-effective in prison settings? ? What is the acceptance/uptake

2019 European Centre for Disease Prevention and Control - Public Health Guidance

23. Public health guidance on screening and vaccination for infectious diseases in newly arrived migrants within the EU/EEA

(International Organisation for Migration), Denis Onyango (Africa Advocacy Foundation), Kathy Attawell and Andreas Sandgren (independent consultants), Alexandra Ortega (International Panel Physicians Association), and Joao Pires and Santino Severoni (World Health Organization, Regional Office for Europe). ECDC would also like to acknowledge the Cochrane and Campbell Equity Methods Group and the following researchers for supporting the systematic evidence reviews, GRADE evidence profiles and GRADE evidence (...) and strongyloidiasis. Charles Hui and Jessica Dunn led the systematic review and provided an initial draft of the chapter on vaccine-preventable diseases. Eric N. Agbata is a doctoral candidate for PhD in Methodology of Biomedical Research and Public Health (Department of Paediatrics, Obstetrics, Gynaecology and Preventive Medicine), Universidad Autònoma de Barcelona, Barcelona, Spain. His contributions to the section on schistosomiasis and strongyloidiasis guidance will form part of his thesis. ECDC would

2019 European Centre for Disease Prevention and Control - Public Health Guidance

24. Programmatic management of latent tuberculosis infection in the European Union

areas in relation to programmatic management of LTBI: target risk groups; diagnosis; treatment and programmatic issues of LTBI management. Evidence-based public health guidance A comprehensive assessment of the public health options for implementing programmatic management of LTBI was conducted. The key topic areas and corresponding research questions were identified through consultation with experts. Scientific evidence was collected using systematic literature reviews, mathematical modelling (...) in the European Union 5 3.2 Evidence collection, appraisal and synthesis 3.2.1 Assessment of scientific evidence A detailed description of the methods for identification, collection and appraisal of scientific evidence, and the corresponding results are provided in a separate report [5]. The following sections briefly summarise the methodology applied. Questions addressed in the guidance The contributions from the inventory of expert opinions were regrouped into four key areas and corresponding main research

2019 European Centre for Disease Prevention and Control - Public Health Guidance

26. Determining the Features of Managed Alcohol Programs

are delivered. • The types of health workers involved in managed alcohol programs include regulated health professionals (dietitians, licensed practical nurses, nurse practitioners, registered nurses, physicians, psychologists and social workers) and unregulated workers (case managers, healthcare aides and personal-care workers).Determining the Features of Managed Alcohol Programs 4 Evidence >> Insight >> Action QUESTIONS • How effective are managed alcohol programs in supporting individuals with severe (...) Evidence >> Insight >> Action KEY MESSAGES Questions • How effective are managed alcohol programs in supporting individuals with severe alcohol-related problems reduce harm? • What are the features of managed alcohol programs that have been implemented in Canada and select comparator countries? Why the issue is important • There are growing concerns globally about the health and social harms caused by alcohol. • Increases in the global burden of disease attributable to alcohol highlight the importance

2019 McMaster Health Forum

27. Learning from the Experience of Accountable Care Organizations in the U.S.

of a question from a policymaker or stakeholder (in this case, the Government of Ontario); 2) identifying, selecting, appraising and synthesizing relevant research evidence about the question; 3) conducting key informant interviews 4) drafting the rapid synthesis in such a way as to present concisely and in accessible language the research evidence; and 5) finalizing the rapid synthesis based on the input of at least two merit reviewers. McMaster Health Forum 5 Evidence >> Insight >> Action Based (...) the experiences of accountable care organizations in the U.S. Hamilton: McMaster Health Forum, 18 July 2019. Product registration numbers ISSN 2292-7999 (online)McMaster Health Forum 3 Evidence >> Insight >> Action KEY MESSAGES Questions • What are accountable care organizations (ACOs) and how have they evolved in the U.S.? • How do general features of public ACOs differ from the proposed design for Ontario Health Teams? • What effects have been achieved through ACOs and what can we learn from

2019 McMaster Health Forum

28. Exploring Models for Health Workforce Planning

of policy reforms, new models of care, changes in labour markets). • This rapid synthesis examines the health workforce planning models in place across select Canadian provinces and comparator jurisdictions to determine what models, processes and characteristics are important to establishing successful predictive models. What we found • We identified three systematic reviews and nine primary studies that related to the questions and complemented these findings with insights from interviews with 11 key (...) a 30- business-day timeframe and involved five steps: 1) submission of a question from a policymaker or stakeholder (in this case, the Ministry of Health in British Columbia); 2) identifying, selecting, appraising and synthesizing relevant research evidence about the question; 3) conducting key informant interviews; 4) drafting the rapid synthesis in such a way as to present concisely and in accessible language the research evidence; and 5) finalizing the rapid synthesis based on the input

2019 McMaster Health Forum

29. Istradefylline (Nourianz) - Parkinson's disease

worsening effect on these important efficacy endpoints. These effects were most clearly observed in patients outside of Japan. A weight effect was not clearly observed in the Japanese trials but most of the patients in these trials were in the 2 lowest weight categories. These results raise the question whether patients outside of Japan experience decreasing istradefylline efficacy as weight increases and that some “heavier” patients might not experience any efficacy from istradefylline. The explanation

2019 FDA - Drug Approval Package

30. Preparing Emerging Leaders for Alternative Futures in Health Systems Across Canada

. Merit review The evidence brief was reviewed by a small number of policymakers, stakeholders and researchers in order to ensure its scientific rigour and system relevance. Acknowledgments We are grateful to the 26 key informants who were interviewed to help with the iterative development of the list of expected futures (which later came to be called ‘alternative futures’), and to the 19 key informants who were interviewed to provide feedback on the terms of reference for this evidence brief. We wish (...) implementation considerations. Whenever possible, the evidence brief summarizes research evidence drawn from systematic reviews of the research literature and occasionally from single research studies. A systematic review is a summary of studies addressing a clearly formulated question that uses systematic and explicit methods to identify, select and appraise research studies and to synthesize data from the included studies. The evidence brief does not contain recommendations, which would have required

2019 McMaster Health Forum

32. Cardiac arrhythmias in coronary heart disease

effective than electrophysiologically-guided class 1 antiarrhythmic therapy in preventing recurrent arrhythmic events and cardiac death. 13 R In patients who have recovered from an episode of sustained ventricular tachycardia (with or without cardiac arrest) who are not candidates for an ICD, amiodarone or sotalol should be considered. Calcium channel blockers Calcium channel blocker therapy in post-MI patients does not reduce all-cause mortality. 13 R Calcium channel blocker therapy is not recommended (...) or cognitive dysfunction (including poor memory and concentration) affecting their ability to participate in treatment regimens and rehabilitation. 223,224 7.2 PSYCHOSOCIAL ASSESSMENT AND SCREENING A systematic review of studies of mood problems following ICD implantation reported that prevalence of depressive disorders and anxiety disorders varied across studies (range 11–28% and 11–26%, respectively, three studies using validated diagnostic interviews, n=190). 225 The authors note that a prevalence rate

2018 SIGN

33. Diagnosis and management of epilepsy in adults

. It does not include patients with a non-epileptic attack disorder (see section 3.3.1). 1.2.2 TARGET USERS OF THE GUIDELINE This guideline will be of interest to all health professionals in primary and secondary care involved in the management of people with epilepsy, including general practitioners, practice nurses, epilepsy specialist nurses, general physicians, emergency department specialists, neurologists, obstetricians, clinical neuropsychologists and psychiatrists. It will also be of interest (...) to those commissioning epilepsy services, public-health physicians, pharmacists, social-work staff, carers and relatives of people with epilepsy and people with epilepsy themselves. 1.3 STATEMENT OF INTENT This guideline is not intended to be construed or to serve as a standard of care. Standards of care are determined on the basis of all clinical data available for an individual case and are subject to change as scientific knowledge and technology advance and patterns of care evolve. Adherence

2018 SIGN

34. Optimisation of RIZIV – INAMI lump sums for incontinence

: To the physicians who participated to the interviews; Gilles Capaert (Service Public Francophone Bruxellois), Kristien Houben (VAPH), Lara Classen (Dienststelle für Selbstbestimmtes Leben der Deutschsprachigen Gemeinschaft Belgiens), Nicolas Fairon (KCE), Mattias Neyt (KCE), Johan Van der Heyden (Sciensano) Reported interests: ‘All experts and stakeholders consulted within this report were selected because of their involvement in the topic. Therefore, by definition, each of them might have a certain degree (...) as a catalyst of communication 180 Figure 36 – Recommended switch to a single form for physicians/GPs 183 10 Incontinence KCE Report 304 LIST OF TABLES Table 1 – PICO 18 Table 2 – Medline search strategy 19 Table 3 – Cochrane search strategy 19 Table 4 – Embase search strategy 20 Table 5 – Neurological causes of incontinence 23 Table 6 – Non-neurological causes of faecal incontinence 24 Table 7 – ICS Recommendations for the treatment of UI 26 Table 8 – Drugs for urgency incontinence with ICS grade

2019 Belgian Health Care Knowledge Centre

35. Bariatric surgery: an HTA report on the efficacy, safety and cost-effectiveness

problems are very prevalent in severely obese patients who are candidates for MBS, and prevalence is even higher in the population of severely or morbidly obese children and young adolescents. (Cf. personal communication and report based on preliminary data analysis from the medical centre taking care of obese children in Walony: Centre Médical Pédiatrique Clairs Vallons ASBL; link to report: Very often, severe and morbid obesity in young people may

2019 Belgian Health Care Knowledge Centre

36. Organisation of mental health care for adults in Belgium

THE BELGIAN HEALTH INTERVIEW SURVEY (HIS) 66 3 RESULTS 67 4 CONCLUSION 71 5 KEY MESSAGES 72 6 REFERENCES 72 CHAPTER 04 INTERNATIONAL FRAMEWORKS FOR MENTAL HEALTH SERVICE ORGANIZATION 73 AUTHORS: RICOUR C 1 , DETOLLENAERE J 1 , CORNELIS J 1 , DEVRIESE S 1 , MISTIAEN P 1 . 73 1 INTRODUCTION 73 2 OVERVIEW OF THE FRAMEWORK DEVELOPMENT DURING THE 21TH CENTURY 74 3 DESCRIPTION OF THE DEVELOPED INTERNATIONAL POLICIES 75 3.1 THE WHO MENTAL HEALTH ACTION PLAN 2013-2020 75 3.2 WHO/EUROPE ACTION PLAN 2013-2020 77 (...) INTERVENTIONS: PRIORITIES AND PREFERENCES 233 KCE Report 318 Organisation Mental Health Care adults Belgium 11 4.6.1 Stakeholders' prioritized organisational interventions, for the overall sample, by region and by stakeholders’ profile 233 4.6.2 Stakeholders' preferred organisational interventions 237 4.6.3 Clustering of organisational interventions 239 4.7 IMPLICIT VALUES OF THE ORGANISATION OF MENTAL HEALTH CARE BEHIND SELECTED ORGANISATIONAL INTERVENTIONS 242 4.8 INTERVIEWS WITH STAKEHOLDERS 244 4.8.1

2019 Belgian Health Care Knowledge Centre

37. Quality indicators for pulmonary rehabilitation programs in Canada: A CTS expert working group report

to develop QI that addresses the pro- cess, structure and outcomes of PR. METHODS: The development process was based on the modified RAND Appropriateness Method that included a systematic review of the literature to identify candidate QI and refinement of these QI by a Working Group before they were sent to a Delphi panel. Panel members rated the import- ance, scientific soundness, reliability, and feasibility of each candidate using an electronic survey. The results of the survey were distributed (...) to panelists who deliberated by teleconference prior their re-rating the candidate QI. RESULTS: The literature review identified 5490 titles and abstracts. A total of 1653 articles were retained after initial screening. After full text screening, 190 articles remained and were used to generate 90 candidate QI. The Delphi panel identified 56 QI: 19 structural, 29 process, 8 outcome. The Working Group distilled these to a shorter list of 14 core QI that defined the minimal requirements for PR. CONCLUSIONS

2019 Canadian Thoracic Society

38. Guidelines on Diagnosis and Management of Syncope

presents with possible TLOC, history taking should first establish whether there was indeed a TLOC. Often, this allows a distinction between the major TLOC groups. The flow diagram for the evaluation of TLOC is shown in Figure . The initial evaluation should answer key questions: Was the event TLOC? In case of TLOC, is it of syncopal or non-syncopal origin? In case of suspected syncope, is there a clear aetiological diagnosis (see section 4.1.1)? Is there evidence to suggest a high risk (...) TLOC, and/or rare causes) are absent. Practical instructions for history taking are given in sections 3 and 4 of the . When epileptic seizures or psychogenic attacks are likely, appropriate steps should be taken. By using a detailed clinical history, physicians can differentiate syncope from other forms of TLOC in approximately 60% of cases. For non-syncopal TLOC, refer to sections 7 and 8. Figure 4 Flow diagram for the initial evaluation and risk stratification of patients with syncope. BP = blood

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2018 European Society of Cardiology

39. Opioid Use Disorder - Diagnosis and Management in Primary Care

are interested in discussing treatment. Delays in starting treatment increase risk of overdose. If possible, same day or next day treatment initiation is preferred. For “mild” OUD (individuals who meet 2-3 of the DSM-5 criteria), consider and discuss starting buprenorphine/naloxone treatment after assessing and discussing the risks and benefits. DSM-5 OUD criteria is not validated in youth. However, youth with significant impairment and high risk of overdose may be good candidates for opioid use disorder (...) treatment including buprenorphine/naloxone treatment. (Refer to (available June 8th, 2018 ) , for youth-specific criteria for starting OAT). If patients are unable or uninterested in starting treatment at this time, keep the door open for future treatment and begin building a rapport. Identify and address patient-centred goals. Follow up on patient goals regularly and consider motivational interviewing and harm reduction counselling. Treatment Options Consider the advantages and disadvantages

2018 Clinical Practice Guidelines and Protocols in British Columbia

40. Management of Stroke in Neonates and Children

challenges. ED providers correctly diagnose a stroke in ≈60% of children, giving ≈40% of cases an incorrect initial diagnosis of a stroke mimic. , Studies of stroke mimics in the ED have yielded several important observations. First, the vast majority (60%–90%) of children presenting to an ED with an acute neurological syndrome, or brain attack, have some condition other than stroke. Diagnoses that commonly mimic stroke and may prompt an emergency physician to activate a “stroke alert” pathway (...) , including pediatricians, emergency physicians, and emergency medical technicians. Similar education programs are needed for subspecialty providers who care for populations at high risk for stroke, including cardiologists, hematologists, cardiac intensivists, and pediatric intensivists, as well as the nursing staff caring for these children. Research: Develop and validate bedside clinical assessment methods for frontline providers to identify stroke in children with improved sensitivity and specificity

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2019 American Heart Association

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