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Interview Questions for the Physician Candidate


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181. Treatment Options for Relapsed or Refractory Multiple Myeloma

Impact Model: Results We used available prevalence data to estimate the number of individuals with MM in the U.S. (approximately 92,000). 44 Data from a claims-based analysis suggested proportions of patients receiving second- and third-line therapy (approximately 37% and 13% respectively). This resulted in candidate population sizes of 33,941 and 11,930 patients. Based on several criteria, we estimated that the theoretical “unmanaged” uptake of these newest regimens would be very high, with 75 (...) % of candidate patients receiving at least one of the regimens of interest by year five following their introduction. Uptake was assumed to be very high because of the gains in progression-free survival that have been demonstrated in available clinical trials as well as acceptable levels of toxicity in most circumstances. Uptake was apportioned equally to the three second-line regimens of interest (i.e., 25% each by year 5) and the four third-line regimens (18.75% each by year 5). Note that this analysis

2017 California Technology Assessment Forum

182. Palliative Care in the Outpatient Setting

. Evidence Tables 95 A9. Key Informant Interviews 120 A10. Policy Roundtable Participants 121 ©Institute for Clinical and Economic Review, 2016 Page v List of Abbreviations Used in this Report ABMS American Board of Medical Specialties ACA Affordable Care Act ACGME Accreditation Council for Graduate Medical Education ACHPN Advanced Certified Hospice and Palliative Nurse ACHP-SW The Advanced Certified Hospice and Palliative Social Worker AIM Advance Illness Management APN Advanced Practice Nurse ATT (...) Lung Cancer PCLC Palliative Care Leadership Center PC Palliative care PCP Primary Care Physician PHQ-9 Patient Health Questionnaire POM Profile of Mood States PPCHETA Palliative Care and Hospice Education and Training Act PPS Palliative Performance Scale PROMIS Patient Reported Outcomes Measurement Information System PRISMA Preferred Reporting Items for Systematic Reviews QoL Quality of Life QUAL-E Quality of Life at the End of Life RCT Randomized Control Trial TOI The Trial Outcome Index USPSTF

2017 California Technology Assessment Forum

183. Staff and Associate Specialist Grade Handbook (Third Edition)

come directly from overseas to take up SAS or other middle grade posts. There are many international medical graduate organisations which offer support and guidance for doctors coming from outside the UK to take up posts in the NHS. The support includes mentoring schemes, induction programmes and web forums. Useful websites • British Association of Physicians of Indian Origin • British International Doctors’ Association • Medical Association of Nigerians Across Great Britain • Association (...) Staff and Associate Specialist Grade Handbook (Third Edition) THIRD EDITION THE SAS HANDBOOK2 THE SAS HANDBOOK THIRD EDITION Dr Olivera Potparic AAGBI SAS Committee Chair FOREWORD Welcome to the third edition of the Association of Anaesthetists of Great Britain & Ireland’s (AAGBI) SAS Handbook. This Handbook aims to be a good reference source for SAS doctors, managers and clinical directors and will be supported by the SAS section of the AAGBI website where further updates will be added. Much

2017 Association of Anaesthetists of GB and Ireland

184. Mepolizumab (Nucala, GlaxoSmithKline plc.) for the Treatment of Severe Asthma with Eosinophilia: Effectiveness, Value, and Value-Based Price Benchmarks

therapies for severe asthma include leukotriene inhibitors, theophylline, and omalizumab. Oral corticosteroids are used for short-term therapy to control asthma exacerbations and chronically for severe asthma that cannot be controlled without these drugs. Physicians try to avoid chronic oral corticosteroid therapy because it is associated with many long-term complications including growth suppression in children, osteoporosis, Cushing’s syndrome, adrenal insufficiency, muscle weakness, diabetes (...) aged 12 years and older. Mepolizumab 100 mg must be reconstituted by a healthcare professional, and is administered subcutaneously once every 4 weeks in a physician’s office. 12 Office administration is required in order to monitor patients for hypersensitivity reactions, a common practice following administration of biologic agents. In this review, we sought to assess the comparative clinical effectiveness and comparative value of adding mepolizumab to standard treatment for severe asthma (inhaled

2017 California Technology Assessment Forum

185. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update

in raw measure of kilograms (kg) and kg·m -2 , which led to higher values used for between-group differences in weight and BMI: mean weight change for lurasidone (doses pooled) versus placebo was 0.45 kg not 2.67 kg, and mean change in BMI was 0.15 kg·m -2 rather than 2.92 kg·m -2 . We updated the following analyses for Key Question 2 about the effect of olanzapine compared with lurasidone on weight gain and BMI: network meta-analysis for body composition outcomes across all conditions; analysis (...) . For more information about AHRQ EPC systematic reviews, see AHRQ expects that these systematic reviews will be helpful to health plans, providers, purchasers, government programs, and the health care system as a whole. Transparency and stakeholder input are essential to the Effective Health Care Program. Please visit the Web site ( to see draft research questions and reports or to join an email list to learn about

2017 Effective Health Care Program (AHRQ)

186. Recommendations on screening for cognitive impairment in older adults

to go see a physician for cognitive impairment screen- ing, 26%) and other things that are more impor- tant for them than screening (36%). 38 Because these participants were relatives of people with a diagnosis of cognitive impairment, it is uncertain whether the findings are generaliz- able to the broader population of candidates for population screening. Suggested performance measures Given that the task force has recommended against screening, a suggested performance mea- sure for this guideline (...) by the recommended course of action. • Practitioners should consider cognitive assessment for patients with signs and symptoms of impairment or when family members or patients express concerns about potential cognitive decline. Key points CMAJ podcasts: author interview at See also Early release, published at on November 30, 2015. Subject to revision.Guidelines 2 CMAJ cognitive impairment (scores of 10–17) and severe

2015 CPG Infobase

187. Diagnosis and management of testosterone deficiency syndrome in men: clinical practice guideline

with testosterone deficiency syndrome who have cardiovascular disease or are at risk of cardiovascular disease. • Hypogonadal men with successfully treated prostate cancer may be candidates for testosterone supplementation; these patients require referral to a specialist, because treatment involves close monitoring by a physician with expertise in the risks and benefits of testosterone therapy. • Regular monitoring for clinical and biochemical response, and for adverse effects, to testosterone replacement (...) . However, hypogonadal men with success- fully treated prostate cancer may be candidates for testosterone supplementation. These patients require referral to a specialist, because treatment involves close monitoring by a physician with expertise in the risks and benefits of testosterone therapy. For more information, see Appendix 1. Implementation The Canadian Men’s Health Foundation is developing a communications plan for the guide- line among its public campaigns to increase awareness of testosterone

2015 CPG Infobase

188. Reducing pain during vaccine injections

of Recommendations Assessment, Development and Evaluation) system provided the general framework for the formulation of recommendations and the synthesis of the research evidence. • We rated candidate clinical questions; a two-thirds majority was set as the cut-off for inclusion in the guideline. • We ranked the importance of each outcome on a scale of 1 to 9. Outcomes with scores from 7 to 9 were classified as critically important, those with scores from 4 to 6 were classified as important, and those (...) and are part of good vaccination clinical practice. • This guideline includes recommendations for pain mitigation based on five domains of pain management interventions (procedural, physical, pharmacologic, psychological and process): the “5P” approach. Key points CMAJ Podcasts: author interview at Early release, published at on August 24, 2015. Subject to revision.Guidelines 2 CMAJ mendations Assessment, Development and Evalu- a tion) (www.grade working

2015 CPG Infobase

189. Diagnosis and management of iliofemoral deep vein thrombosis: clinical practice guideline

, whereas select patients with iliofemoral DVT are candidates for endovascular thrombus removal to prevent sequelae of post-thrombotic syndrome. • Compression therapy may be considered for the treatment of established post-thrombotic syndrome, but it is unlikely to prevent development of the syndrome. Key points CMAJ Podcasts: author interview at: Early release, published at on September 28, 2015. Subject to revision.Guidelines 2 CMAJ Panel (...) , are resource intensive and have their own potential complications. Scope This guideline is intended to assist Canadian pri- mary care physicians in the assessment and man- agement of patients with iliofemoral DVT. We include guidance as to which patients may bene- fit from early triage and transfer to tertiary care institutions for clot removal and reduction, a crit- ical aspect in the management of this condition. Methods This consensus guideline provides recommenda - tions on the diagnosis and management

2015 CPG Infobase

191. Recommendations for growth monitoring, prevention and management of overweight and obesity in children and youth in primary health care 2015

in children and youth aged 2 to 17 years. Methods The Canadian Task Force on Preventive Health Care is an independent panel of clinicians and methodologists that makes recommendations about clinical manoeuvres aimed at primary and secondary prevention (www.canadiantaskforce .ca). Work on each set of recommendations is led by a workgroup of two to six members of the task force. Each workgroup establishes the research questions and analytical framework for the guide- line, which are incorporated (...) of current members of the Canadian Task Force on Preventive Health Care is available at canadiantask Correspondence to: Canadian Task Force on Preventive Health Care, CMAJ 2015. DOI:10.1503 /cmaj.141285 CMAJ Podcasts: author interview at See also pages 387 and 389 as well as,, CMAJ Open

2015 CPG Infobase

192. Dialysis Programs

determined on the basis of interviews with key informants. In the updated survey, questions were included if they focused mainly on nephrologists’ current practices and perspectives about various facilitators and resources as they related to the implementation of the dialysis modalities of interest. The nephrologists were asked about their support for various suggested policies, initiatives, practices, and resources that could play a role in supporting the uptake of home-based dialysis or in-centre self (...) physicians and nephrologists (n = 5 or 14.7%). Nephrologist Survey Of 249 potential respondents, 28 (11.2%) provided information. Responses to all or some of the questions were received from nephrologists in Alberta (n = 4), British Columbia (n = 2), Manitoba (n = 4), New Brunswick (n = 2), Newfoundland and Labrador (n = 1), Nova Scotia (n = 1), Ontario (n = 12), and Quebec (n = 2). No responses were received from nephrologists in the Northwest Territories, Nunavut, Prince Edward Island, Saskatchewan

2016 Canadian Agency for Drugs and Technologies in Health - Environmental Scanning

193. Communication strategies for the prevention of HIV, STI and hepatitis among MSM in Europe

of interventions against their stated objectives Focus group A group interview method designed to elicit feedback on specific questions Health promotion The process of enabling people to increase control over and improve their health. Health promotion moves beyond a focus on individual behaviour towards a wide range of social and environmental interventions [1]. HIV status/ serostatus Refers to whether an individual is infected with HIV, i.e. HIV is detected in a person’s body or not: HIV positive = HIV (...) body type 31 Tables Table 1: Knowledge questions for messages of HIV, STI, and viral hepatitis prevention 12 Table 2: Prevention messages about knowledge of HIV 13 Table 3: Prevention messages about knowledge of STIs 13 Table 4: Prevention messages about knowledge of viral hepatitis 14 Table 5. Prevention messages about testing 15 Table 6: Prevention messages about using condoms and lubricants 17 Table 7: Prevention messages about avoiding semen in the mouth 18 Table 8: Prevention messages about

2016 European Centre for Disease Prevention and Control - Technical Guidance

194. Improving healthcare providers? face-to-face interactions with clients living with or at-risk for HIV

Improving healthcare providers? face-to-face interactions with clients living with or at-risk for HIV RAPID RESPONSE SERVICE | #111, AUGUST 2016 1 RAPID RESPONSE SERVICE THE ONTARIO HIV TREATMENT NETWORK Question • What face-to-face interventions have proven effective in helping providers educate clients and improve their health literacy? References 1. Price-Haywood EG, Harden- Barrios J, Cooper LA. Comparative effectiveness of audit-feedback versus additional physician communication training (...) simple language, using diagrams, using the Teach-Back method). Clients rated physicians who underwent the training higher on general communication and shared decision-making, but client knowledge did not significantly improve as result of the intervention. • Seligman and colleagues (4) conducted a study to determine if notifying doctors about clients with lower health literacy would affect their behaviour toward these clients during appointments. Clients were screened for their health literacy level

2016 Ontario HIV Treatment Network

195. Dyslipidaemias (Full text)

to help them maintain this status. Thus the intensity of preventive actions should be tailored to the patient's total CV risk. The strongest driver of total CV risk is age, which can be considered as ‘exposure time’ to risk factors. This raises the issue that most older people in high-risk countries who smoke would be candidates for lipid-lowering drug treatment even if they have satisfactory blood pressure levels. The clinician is strongly recommended to use clinical judgment in making therapeutic

2016 European Society of Cardiology PubMed abstract

196. Physical Therapy Evaluation and Treatment After Concussion/Mild Traumatic Brain Injury

symptoms, prognosis, and self-management strate- gies and refer for consultation with other health care providers as indicated. Comprehensive Intake Interview A Physical therapists must conduct and document a com- prehensive intake of past medical history, review of men- tal health history, injury-related mechanisms, injury-related symptoms, and early management strategies for patients who have experienced a concussive event. EXAMINATION Systems to Be Examined B For patients identified as safe (...) of sleep, safe return-to-activity pacing strategies, and potential signs and symptoms of the need for fol- low-up care with a physician, physical therapist, or other health care provider. A Physical therapists must educate patients who have expe- rienced a concussive event and their families/ caregivers about the various symptoms, impairments, and functional limita- tions that are associated with concussion, and stress that most patients with concussion recover relatively quickly. Providing

2020 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

197. Hepatitis B and C testing: people at risk of infection

Prison 50 Sexual contact 50 9 References 51 Appendix A Membership of the Programme Development Group (PDG), the NICE project team and external contractors 53 Programme Development Group 53 NICE project team 54 External contractors 55 Expert testimony 55 Appendix B Summary of the methods used to develop this guidance 57 Introduction 57 Guidance development 57 Key questions 57 Reviewing the evidence 58 Cost effectiveness 61 How the PDG formulated the recommendations 62 Appendix C The evidence 64

2012 National Institute for Health and Clinical Excellence - Clinical Guidelines

198. Addyi - Flibanserin

dysfunction: a systematic review and meta-analysis. Arch Sex Behav 2013;42(6):915-33. 5 In 2006, Intrinsa TTS (testosterone transdermal system) was approved in Europe for the treatment of HSDD in surgically menopausal women on concomitant estrogen replacement. In 2012, the marketing authorization holder, Warner Chilcott, voluntarily withdrew the marketing authorization for “commercial reasons.” 6 Based on a question “How strong is your sex drive?” included in the Arizona Sexual Experiences Scale (ASEX (...) Flibanserin Oral Tablet 100 mg Page 4 of 52 ? The need to further evaluate the risk of accidental injury with root cause analysis ? The need to assess the human abuse potential The CR letter recommended that the Applicant conduct one new Phase 3 trial with fewer exclusion criteria to allow enrolment of a broader HSDD population. Given the concerns with content validity of the two FSFI-desire questions and the long recall period (28 days), the letter also stated that the instrument used to assess effects

2015 FDA - Drug Approval Package

199. Patient safety in primary healthcare: a review of the literature

, and analytic when the aim was to determine factors associated with risks. 1.2 Studies included in the literature that evaluated the effect of interventions to minimise risks to patient safety required experimental designs. These included randomised control trials and quasi-experimental study designs. 1.3 Studies that addressed questions on the evidence of risk associated with patient safety in primary healthcare used a range of qualitative methods (for example focus groups and semi-structured interviews (...) Analytic Experimental Randomised controlled trial Quasi experimental Observational Cohort Study Cross-sectional (Analytic) Case-control study 17 PATIENT SAFETY IN PRIMARY HEALTHCARE | SAX INSTITUTE Question 1: What was the aim of the study? If the aim of the research was to simply describe a population (P) or outcome (O), then it was a descriptive study. These were often surveys or qualitative studies, for example using focus groups or semi-structured interviews. A study that describes the nature

2015 Sax Institute Evidence Check

200. Guidance on the clinical management of depressive and bipolar disorders, specifically focusing on diagnosis and treatment strategies

by psychiatrists, psychologists, physicians and others with an interest in mental health care. Conclusions: The Mood Disorder CPG is the first Clinical Practice Guideline to address both depressive and bipolar disorders. It provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus. Mood Disorders Committee: Professor Gin Malhi (Chair), Professor Darryl Bassett, Professor Philip Boyce, Professor Richard Bryant, Professor Paul Fitzgerald, Dr (...) . The guideline is primarily directed at psychiatrists, psychologists and physicians with a particular interest in mental health issues. It will also be of benefit to other mental health care professionals, hospital administrators and government policy makers. It amalgamates evidence-based knowledge with clinical wisdom and makes recommendations for real-world practice. Structure. The Mood Disorders CPG comprises four sections: Section 1: Classification of mood disorders Section 2: Clinical management

2015 Royal Australian and New Zealand College of Psychiatrists

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