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41. I Ching Balance Acupuncture Treatment of Migraines, Insomnia, and Depression in a Post-Ovariectomy Patient Receiving Hormone Replacement Therapy (PubMed)

, and was prescribed hormone replacement therapy. Deteriorating QoL caused her to seek acupuncture for migraines, insomnia, and depression. The outcomes sought for treatment of this case included intensity, duration, and frequency of migraines, insomnia, and depression, as well as her QoL. The outcome measures were estimated monthly throughout her treatment. Each was rated on a numeric scale of 0-10 (0 = "the lowest possible" and 10 = "the worst imaginable"). At baseline, the patient rated the intensity, duration (...) , and frequency of each complaint as 10. She was treated with 60-minute, I Ching Balance Acupuncture (ICBA) sessions once per week for 7 months. Results: This acupuncture treatment did not cause any adverse events, pain, or discomfort. Her migraines, insomnia, and depression decreased to a great extent. In addition, this patient reported considerable improvement in her QoL. The improvement in her QoL was inversely related to the intensity, duration, and frequency of her complaints throughout her acupuncture

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2018 Medical Acupuncture

42. Suanzaoren Formulae for Insomnia: Updated Clinical Evidence and Possible Mechanisms (PubMed)

Suanzaoren Formulae for Insomnia: Updated Clinical Evidence and Possible Mechanisms Insomnia disorder is a widespread and refractory disease. Semen Ziziphi Spinosae, Suanzaoren, a well-known Chinese herbal medicine, has been used for treating insomnia for thousands of years. Here, we aimed to assess the available evidence of Chinese herbal formulae that contains Suanzaoren (FSZR) for insomnia according to high-quality randomized controlled trials (RCTs) and reviewed their possible mechanisms (...) studies with 1,454 patients were identified. Meta-analysis of high-quality RCTs showed that FSZR monotherapy was superior to placebo (P < 0.01); FSZR plus Diazepam was superior to Diazepam alone (P < 0.05); there were mixed results comparing FSZR with Diazepam (P > 0.05 or P < 0.05). Furthermore, FSZR caused fewer side effects than that of Diazepam. Suanzaoren contains complex mixtures of phytochemicals including sanjoinine A, Jujuboside A, spinosin and other flavonoids, which has sedative

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2018 Frontiers in pharmacology

43. Assessment of Switching to Suvorexant versus the Use of Add-on Suvorexant in Combination with Benzodiazepine Receptor Agonists in Insomnia Patients: A Retrospective Study (PubMed)

Assessment of Switching to Suvorexant versus the Use of Add-on Suvorexant in Combination with Benzodiazepine Receptor Agonists in Insomnia Patients: A Retrospective Study Suvorexant is a novel hypnotic drug that does not interact with the conventional γ-aminobutyric acid (GABA)-A receptor. We investigated the method by which suvorexant was introduced in insomnia patients who were taking benzodiazepine receptor agonists (BzRA).This was a retrospective study. We extracted clinical data (...) for patients who were prescribed suvorexant and were already using BzRA. The patients were assigned to two groups, the switching and add-on groups. We assessed the suvorexant discontinuation rate at one month after the prescription of the drug.One hundred and nineteen patients were assigned to the switching group, and 109 were assigned to the add-on group. The add-on group exhibited a significantly higher all-cause discontinuation rate than the switching group (odds ratio, 2.7; 95% confidence interval, 1.5

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2018 Clinical Psychopharmacology and Neuroscience

44. Insomnia and Mild Cognitive Impairment (PubMed)

hypoglycemia, as a cause of middle insomnia, is the main focus of this case study. Other types of insomnia are also briefly reviewed. The management of insomnia is then discussed including sleep hygiene, the usefulness and potential drawbacks of dietary supplements, nonprescription over-the-counter preparations and prescription hypnotics. Sleep architecture is then briefly reviewed, emphasizing the importance of its integrity and the role of each sleep stage. (...) Insomnia and Mild Cognitive Impairment Insomnia is a common problem in older people, especially in patients with mild cognitive impairment (MCI) whose circadian rhythm is often compromised. Insomnia exerts such a toll on caregivers that it is frequently the primary reason for seeking to institutionalize their loved ones. Three different types of insomnia are recognized: sleep-onset or initial insomnia, sleep maintenance or middle insomnia, and early morning awakening or late insomnia. Nocturnal

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2018 Gerontology and geriatric medicine

45. Study of the Effects of HIRREM-SOP for Insomnia

Study of the Effects of HIRREM-SOP for Insomnia Study of the Effects of HIRREM-SOP for Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of the Effects of HIRREM-SOP for Insomnia The safety (...) by (Responsible Party): Wake Forest University Health Sciences Study Details Study Description Go to Brief Summary: Prior research studies have shown benefit for use of a technique called High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), to reduce symptoms of moderate to severe insomnia. HIRREM uses scalp sensors to monitor brain electrical activity, and software algorithms translate selected brain frequencies into audible tones in real time. Those tones (acoustic

2018 Clinical Trials

46. Effects of Self-help Versus Group Cognitive Behavioural Therapy for Insomnia in Youth

Effects of Self-help Versus Group Cognitive Behavioural Therapy for Insomnia in Youth Effects of Self-help Versus Group Cognitive Behavioural Therapy for Insomnia in Youth - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Effects of Self-help Versus Group Cognitive Behavioural Therapy for Insomnia in Youth The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03522701 Recruitment Status : Recruiting First Posted : May 11, 2018 Last

2018 Clinical Trials

47. Reducing Health Disparities for Black Women in the Treatment of Insomnia

Reducing Health Disparities for Black Women in the Treatment of Insomnia Reducing Health Disparities for Black Women in the Treatment of Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Reducing (...) Health Disparities for Black Women in the Treatment of Insomnia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03613519 Recruitment Status : Not yet recruiting First Posted : August 3, 2018 Last Update Posted : August 16

2018 Clinical Trials

48. Non-deceptive Application of Placebos in Insomnia

for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: age between 18 years to 69 years fluent in German language provide written informed consent ability to understand the explanations and instructions given by the study physician and the investigator Exclusion Criteria: evidence for sleep disorders caused by medical factors (e.g. sleep apnea, restless legs syndrome, narcolepsy, substance-induced insomnia) allergies to ingredients of placebo patients scoring below 8 or above 21 (...) Non-deceptive Application of Placebos in Insomnia Non-deceptive Application of Placebos in Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Non-deceptive Application of Placebos in Insomnia (NAP

2018 Clinical Trials

49. Cancer, Obesity/Overweight and Insomnia Study

Cancer, Obesity/Overweight and Insomnia Study Cancer, Obesity/Overweight and Insomnia Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Cancer, Obesity/Overweight and Insomnia Study (COIN) The safety (...) : Under Armour Information provided by (Responsible Party): Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Study Details Study Description Go to Brief Summary: This is a randomized pilot study to better understand the relationships among insomnia, weight loss, and breast cancer. This study will assess the effectiveness of a sleep intervention prior to a web- and phone-based weight loss program. Condition or disease Intervention/treatment Phase Breast Cancer Overweight and Obesity Insomnia

2018 Clinical Trials

50. National Adaptive Trial for PTSD Related Insomnia

is a form of intense anxiety which sometimes results from severe trauma. Symptoms may include nightmares, flashbacks, troublesome memories, difficulty sleeping, poor concentration, irritability, anger, and emotional withdrawal. Insomnia is a disorder that can make it hard to fall sleep, stay asleep or cause a person to wake up too early and not be able to fall back to sleep. Condition or disease Intervention/treatment Phase Insomnia Drug: Trazodone Drug: Eszopiclone Drug: Gabapentin Other: Placebo Phase (...) National Adaptive Trial for PTSD Related Insomnia National Adaptive Trial for PTSD Related Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. National Adaptive Trial for PTSD Related Insomnia (NAP

2018 Clinical Trials

51. The Effect of Cognitive Behavioral Therapy for Insomnia on Type 2 Diabetes Health Outcomes

components. Behavioral: Cognitive behavioral therapy for insomnia CBT-I is designed to change sleep habits as well as direct misconceptions about sleep and insomnia. Participants will receive several face-to-face interview techniques: sleep restriction therapy, stimulus control procedures, sleep hygiene, relaxation training and cognitive components. The intervention will be provided in 6-session (one session/week). Active Comparator: Diabetes Education Sleep hygiene, foot care, causes and diagnosis (...) The Effect of Cognitive Behavioral Therapy for Insomnia on Type 2 Diabetes Health Outcomes The Effect of Cognitive Behavioral Therapy for Insomnia on Type 2 Diabetes Health Outcomes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2018 Clinical Trials

52. Response Inhibition Deficits in Insomnia Disorder: An Event-Related Potential Study With the Stop-Signal Task (PubMed)

Response Inhibition Deficits in Insomnia Disorder: An Event-Related Potential Study With the Stop-Signal Task Background: Response inhibition is a hallmark of executive function, which was detected impaired in various psychiatric disorders. However, whether insomnia disorder (ID) impairs response inhibition has caused great controversy. Methods: Using the auditory stop-signal paradigm coupled with event-related potentials (ERPs), we carried out this study to examine whether individuals with ID (...) inhibition among insomniacs. Their reaction time in go trials, however, showed no significant between-group difference. Considering the electrophysiological correlate underlying the longer SSRT, we found reduced P3 amplitude in patients with insomnia in the successful stop trials, which might reflect their poor efficiency of response inhibition. Finally, when we performed exploratory analyses in the failed stop and go trials, patients with ID presented reduced Pe and N1 amplitude in the failed sop trials

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2018 Frontiers in neurology

53. Ball Blankets on Insomnia in Depression in Outpatient Clinics

Ball Blankets on Insomnia in Depression in Outpatient Clinics Ball Blankets on Insomnia in Depression in Outpatient Clinics - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Ball Blankets on Insomnia (...) of Aarhus Collaborators: Innovation Fund Denmark Protac A/S Aarhus University Hospital Odense University Hospital Information provided by (Responsible Party): University of Aarhus Study Details Study Description Go to Brief Summary: The objective of the study is to examine the efficacy of Protac Ball BlanketsTM (PBB) and specifically if the PBB will extend the total sleep time of patients with insomnia due to depression in two psychiatric outpatient clinics at Aarhus University Hospital and Odense

2018 Clinical Trials

54. Association of Chronic Insomnia With Mortality and Adverse Renal Outcomes. (PubMed)

Association of Chronic Insomnia With Mortality and Adverse Renal Outcomes. To examine whether chronic insomnia is associated with an increased risk of adverse renal outcomes and all-cause mortality.We examined associations of chronic insomnia (defined as the presence of both International Classification of Diseases, Ninth Revision codes 307.42, 307.49, and 780.52 and long-term use of insomnia medications) with adverse renal outcomes (end-stage renal disease, incidence of estimated glomerular (...) filtration rate [eGFR] ≤45 mL/min per 1.73 m2, and eGFR slopes <-3.0 mL/min per 1.73 m2 per year) and all-cause mortality in a national cohort of 1,639,090 US veterans by using Cox proportional hazards and logistic regression models with multivariable adjustments.A total of 36,741 patients (2.24%) had chronic insomnia; 32,985 (89.8%) were male and 28,090 (76.5%) were white, with a mean baseline eGFR of 84.1±16.4 mL/min per 1.73 m2. Chronic insomnia was associated with a significantly higher risk of eGFR

2018 Mayo Clinic Proceedings

55. Chronic insomnia: therapies to start, therapies to stop

Chronic insomnia: therapies to start, therapies to stop The AFP Community Blog: Chronic insomnia: therapies to start, therapies to stop | Monday, September 24, 2018 - Kenny Lin, MD, MPH Can't sleep? Then spend your extra awake time reading the latest installment of in the September 1 issue of AFP , on . This evidence review, which supported an , examined the effectiveness of and for adults with insomnia disorder, defined as "poor sleep quality or quantity that causes distress or dysfunction (...) and lasts for longer than three months." The most beneficial sleep intervention overall is cognitive behavior therapy for insomnia (CBT-I), which produced sustained improvements for at least 6 months. CBT-I consists of cognitive therapy, sleep restriction and stimulus control, and sleep hygiene education. Medications that have sufficient evidence demonstrating improvement in short-term (3 months or less) sleep outcomes include eszopiclone, zolpidem, and suvorexant; there was insufficient data

2018 The AFP Community Blog

56. Provider Supported Self-Help Cognitive Behavioral Therapy for Insomnia (Tele-Self CBTI)

in depression, anxiety, suicidality, disability due to a mental health disorder, hypertension, obesity, metabolic syndrome, diabetes, and all-cause mortality, thus serving as an additional risk factor for some of the most common medical conditions seen in patients utilizing the VA healthcare system. Cognitive-Behavioral Therapy for Insomnia (CBTI) produces both short-term and sustained resolution of insomnia with fewer adverse side effects than pharmacotherapy. But access to behavioral sleep medicine (...) Provider Supported Self-Help Cognitive Behavioral Therapy for Insomnia (Tele-Self CBTI) Provider Supported Self-Help Cognitive Behavioral Therapy for Insomnia (Tele-Self CBTI) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2018 Clinical Trials

57. Traditional Use of Chinese Herbal Medicine for Insomnia and Priorities Setting of Future Clinical Research. (PubMed)

treatments were mentioned in 940 citations, and insomnia diagnosis treated with Chinese herbal formulae was specifically described in 800 citations. The traditional use of CHM appeared to be individualized based on the cause, pathogenesis, phase, phenotype, demographics, and concurrent medical conditions of insomnia. The most common herbal formulae for insomnia included Wen dan tang, Suan zao ren tang, Ban xia shu mi tang, and Gui pi tang. The most frequently cited herb was suan zao ren (Ziziphi spinosae (...) Traditional Use of Chinese Herbal Medicine for Insomnia and Priorities Setting of Future Clinical Research. To evaluate the traditional use of Chinese herbal medicine (CHM) for insomnia in pre-contemporary times.The Encyclopedia of Traditional Chinese Medicine (fifth edition) was systematically searched using seven Chinese medicine disease nomenclatures to identify insomnia citations. Citations were coded, and frequently used herbal formulae specific for insomnia were analyzed.Insomnia

2018 Journal of Alternative and Complementary Medicine

58. Effectiveness and safety of warm needle acupuncture on insomnia: Protocol for a systematic review and meta-analysis. (PubMed)

)]. Sleep quality value of the patient will be considered as the primary outcome and the secondary outcome will include biochemical, indicators total scores on the insomnia severity index, quality of life, adverse events caused by WNA, and changes of symptom in Traditional Chinese Medicine. The selection of the studies will be performed by EndnoteX7 software. All analyses will be conducted by using RevMan software V5.3.This study will provide a rational synthesis of current evidences for warm needle (...) Effectiveness and safety of warm needle acupuncture on insomnia: Protocol for a systematic review and meta-analysis. Warm needle acupuncture (WNA) combines acupuncture and moxibustion, which is an integral part of the acupuncture therapy. Insomnia is a common sleep disorder, which affects sub-healthy people and patients with chronic disease. The clinical practice indicates that WNA has a therapeutic effect on insomnia. Here we will provide a protocol to explore the effectiveness and safety

2018 Medicine

59. Suvorexant (Belsomra) for the Treatment of Bipolar Depression With Insomnia

at Screen visit, Baseline visit (Week 0), Week 2, Week 4, Week 6, Week 8, Week 10, Week 12, and Week 14. ] The ISI measures the subjective symptoms and consequences of difficulties initiating and maintaining sleep and self-perception of insomnia symptoms as well as the degree of concerns or distress caused by those symptoms. This scale includes 7 items, each scored on a 0-4 scale. Items are summed to produce a total score with a maximum of 28 and minimum of 0. Change in total score (sum of scores from 7 (...) Suvorexant (Belsomra) for the Treatment of Bipolar Depression With Insomnia Suvorexant (Belsomra) for the Treatment of Bipolar Depression With Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

60. Insomnia symptoms and mortality from all causes, cardiovascular disease, and cancer: systematic review and meta-analysis of cohort studies

Insomnia symptoms and mortality from all causes, cardiovascular disease, and cancer: systematic review and meta-analysis of cohort studies Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2018 PROSPERO

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