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Insomnia Causes

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21. E-aid Cognitive Behavior Therapy for Insomnia to Prevent Transition From Short-term to Chronic Insomnia in China

E-aid Cognitive Behavior Therapy for Insomnia to Prevent Transition From Short-term to Chronic Insomnia in China E-aid Cognitive Behavior Therapy for Insomnia to Prevent Transition From Short-term to Chronic Insomnia in China - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. E-aid Cognitive Behavior Therapy for Insomnia to Prevent Transition From Short-term to Chronic Insomnia in China The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03302455 Recruitment Status : Enrolling by invitation First Posted

2017 Clinical Trials

22. Music for insomnia in adults. (PubMed)

Music for insomnia in adults. Insomnia is a common sleep disorder in modern society. It causes reduced quality of life and is associated with impairments in physical and mental health. Listening to music is widely used as a sleep aid, but it remains unclear if it can actually improve insomnia in adults.To assess the effects of listening to music on insomnia in adults and to assess the influence of specific variables that may moderate the effect.We searched CENTRAL, PubMed, Embase, nine other (...) of the intervention compared to no treatment or treatment-as-usual.Only one study (N = 50; low-quality evidence) reported data on sleep onset latency, total sleep time, sleep interruption, and sleep efficiency. However, It found no evidence to suggest that the intervention benefited these outcomes. None of the included studies reported any adverse events.The findings of this review provide evidence that music may be effective for improving subjective sleep quality in adults with insomnia symptoms

2015 Cochrane

23. Benefits and Harms of Cranial Electrical Stimulation for Chronic Painful Conditions, Depression, Anxiety, and Insomnia: A Systematic Review. (PubMed)

with insomnia (n = 2), insomnia and anxiety (n = 1), or depression (n = 3) had inconclusive or conflicting results. Low-strength evidence suggested that CES does not cause serious side effects.Most trials had small sample sizes and short durations; all had high risk of bias due to inadequate blinding.Evidence is insufficient that CES has clinically important effects on fibromyalgia, headache, neuromusculoskeletal pain, degenerative joint pain, depression, or insomnia; low-strength evidence suggests modest (...) Benefits and Harms of Cranial Electrical Stimulation for Chronic Painful Conditions, Depression, Anxiety, and Insomnia: A Systematic Review. Cranial electrical stimulation (CES) is increasingly popular as a treatment, yet its clinical benefit is unclear.To review evidence about the benefits and harms of CES for adult patients with chronic painful conditions, depression, anxiety, and insomnia.Several databases from inception to 10 October 2017 without language restrictions and references from

2018 Annals of Internal Medicine

24. Effectiveness and safety of fire-needle moxibustion on insomnia: Protocol for a systematic review and meta-analysis. (PubMed)

). Pittsburgh Sleep Quality Index will be considered as the primary outcome, and the secondary outcome will include biochemical, indicators total scores on the insomnia severity index, quality of life, adverse events caused by FNM, and changes of TCM syndromes scores. Review Manager 5.2 software will be use for assessment of risk of bias, data synthesis. Begg and Egger tests will be use for assessing symmetries of funnel plot by software Stata 12.0. Methodological quality will be assessed with the risk (...) Effectiveness and safety of fire-needle moxibustion on insomnia: Protocol for a systematic review and meta-analysis. Fire-needle moxibustion (FNM) is an ancient method of external therapy that combines acupuncture with moxibustion, and has the property of high temperature resistance. Insomnia is a major public health problem and strongly associated with a high prevalence, impact on daily life, comorbidity with other disorders, and societal costs. The clinical practice demonstrates that FNM has

2019 Medicine

25. Hong Kong Chinese Medicine Clinical Practice Guideline for Cancer Palliative Care: Pain, Constipation, and Insomnia. (PubMed)

Hong Kong Chinese Medicine Clinical Practice Guideline for Cancer Palliative Care: Pain, Constipation, and Insomnia. It is common for patients with cancers in Hong Kong seeking Chinese Medicine (CM) therapies as supportive care during cancer treatment and to manage treatment-related side effects. This article provides clinical practice guideline (CPG) on the use of CM for specific clinical indications caused by cancer and during cancer treatment, including pain, constipation, and insomnia

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2019 Evidence-based Complementary and Alternative Medicine (eCAM)

26. <i>Albizia julibrissin</i> Ameliorates Memory Loss Induced by Insomnia in <i>Drosophila</i>. (PubMed)

Albizia julibrissin Ameliorates Memory Loss Induced by Insomnia in Drosophila. In clinical practice in Taiwan, Albizia julibrissin is the most prescribed Chinese herbal medicine for insomnia. Short-term insomnia and hypnotic use both attenuate cognitive functions, especially learning memory. In previous studies, A. julibrissin exhibits sedative activity, antidepressant-like effects, and protection of learning and memory against amnesia. However, whether A. julibrissin ameliorates (...) memory loss caused by short-term sleep deprivation is not clear. We utilized the sleep-deprived Drosophila model and olfactory associative learning-memory assay to test the effects of A. julibrissin on sleep-deprivation induced memory loss. We found that A. julibrissin ameliorated 3-hour memory but not 1-hour memory or instant learning. The findings might be applied to an anticipated short-term sleep disturbance.

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2019 Evidence-based Complementary and Alternative Medicine (eCAM)

27. Pneumonia caused by proton pump inhibitors (PPI)

Pneumonia caused by proton pump inhibitors (PPI) MED CHECK - TIP December 2017 / Vol.3 No.9 · Page 27 -The Informed Prescriber C N o 9 M ED HECK D e ce m b e r 2 0 1 7 WHO downgrades Tamiflu Suvorexant : A hypnotic causing cataplexy Insomnia, Sleep Duration, Harm of hypnotics PPI causes Pneumonia Editorial WHO downgraded oseltamivir (Tamiflu) New Products Hypnotic (sleeping pill), suvorexant (brand name Belsomra) A substance that causes narcolepsy and cataplexy Teriparatide More harm than (...) benefit: Review Insomnia, Optimal Sleep Duration and Harm of Sleeping pills Pneumonia caused by proton pump inhibitors (PPI) (1) meta-analysis (2) Critical appraisal of a study CONTENTS (December 2017, Vol. 3, No. 9 ) 28 29 34 36 40 42 Volume 3 Page 28 · MED CHECK - TIP December 2017/ Vol.3 No.9 WHO downgrades Tamiflu after reviewing evidence WHO (World Health Organization) reviews their model list of essential medicines every two years. In the revision launched in June 2017, oseltamivir (Tamiflu

2018 Med Check - The Informed Prescriber

28. Chronic Insomnia in Older Adults

cause daytime sedation caution: driving {Anecdotally: the 15mg may be more sedating than higher doses because of increased affinity for anticholinergic receptors at the lower dose.} [Doxepin SILENOR 3,6mg: new ultra-low dose of old TCA indicated for insomnia .] 16 From the BEERS Criteria 2012 : ? Avoid benzodiazepines for the treatment of insomnia; ?risk of cognitive impairment, delirium, falls, fractures & motor vehicle accidents high quality, strong recommendation ? Avoid chronic use (>90 days (...) at bedtime o Oxazepam SERAX 10 to 15mg at bedtime Consider the presence of co-morbid conditions to optimize other agents: • BPSD – aggression, psychosis, agitation: o SB Quetiapine SEROQUEL 12.5 mg to 25 mg at bedtime • Chronic pain: o SB TCA: Nortriptyline AVENTYL 10 to 25 mg at bedtime ( ? anticholinergic activity & hypotension compared to amitriptyline but still requires cautious initiation) Approach to Insomnia ? Manage any underlying cause of insomnia or associated comorbidities Anxiety BPH

2013 RxFiles

29. Blocking nocturnal blue light for insomnia: A randomized controlled trial. (PubMed)

Blocking nocturnal blue light for insomnia: A randomized controlled trial. The use of light-emitting electronic devices before bedtime may contribute to or exacerbate sleep problems. Exposure to blue-wavelength light in particular from these devices may affect sleep by suppressing melatonin and causing neurophysiologic arousal. We aimed to determine if wearing amber-tinted blue light-blocking lenses before bedtime improves sleep in individuals with insomnia. Fourteen individuals (n = 8 females (...) ; age ± SD 46.6 ± 11.5 y) with insomnia symptoms wore blue light-blocking amber lenses or clear placebo lenses in lightweight wraparound frames for 2 h immediately preceding bedtime for 7 consecutive nights in a randomized crossover trial (4-wk washout). Ambulatory sleep measures included the Pittsburgh Insomnia Rating Scale (PIRS) completed at the end of each intervention period, and daily post-sleep questionnaire and wrist-actigraphy. PIRS total scores, and Quality of Life, Distress, and Sleep

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2018 Journal of psychiatric research

30. Acupuncture in the Modulation of Peripheral Oxidative Stress Insomnia

: The Hong Kong Polytechnic University Information provided by (Responsible Party): YEUNG Wing Fai, The Hong Kong Polytechnic University Study Details Study Description Go to Brief Summary: A randomized controlled trial involving 140 subjects with (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) DSM-5 insomnia disorder after excluding those with other medical conditions, psychiatric disorders, and sleep disorders that may cause insomnia. The subjects will be randomly assigned (...) , and to examine its effects on oxidative stress parameters in subjects with primary insomnia disorder. Methods: This will be a randomized controlled trial involving 140 subjects with DSM-5 insomnia disorder after excluding those with other medical conditions, psychiatric disorders, and sleep disorders that may cause insomnia. The subjects will be randomly assigned to either acupuncture treatment or sham acupuncture (control group) in a 1:1 ratio. The acupuncture treatment group will receive acupuncture

2018 Clinical Trials

31. Effects of Group Cognitive Behavioural Therapy on Comorbid Insomnia and Depression in Youth

Effects of Group Cognitive Behavioural Therapy on Comorbid Insomnia and Depression in Youth Effects of Group Cognitive Behavioural Therapy on Comorbid Insomnia and Depression in Youth - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Effects of Group Cognitive Behavioural Therapy on Comorbid Insomnia and Depression in Youth The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03438331 Recruitment Status : Recruiting First Posted

2018 Clinical Trials

32. Low-intensity Cognitive-behavioural Therapy for Insomnia

in quality of life. Insomnia is prevalent in Hong Kong and can cause severe impacts on patients and society, but there is a dearth of related research in the local population. Therefore, it is significant to conduct this study. A total of 210 participants aged > 18 with insomnia will be recruited and randomized into 3 groups to receive one of the 3 treatments. Outcomes will be measured using relevant questionnaires filled in at the baseline, 6 and 12 weeks afterwards. The results obtained (...) Low-intensity Cognitive-behavioural Therapy for Insomnia Low-intensity Cognitive-behavioural Therapy for Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Low-intensity Cognitive-behavioural Therapy

2018 Clinical Trials

33. Acupuncture for perimenopausal insomnia: A systematic review and meta-analysis protocol. (PubMed)

as the primary outcome. Secondary outcomes include biochemical indicators, such as hormone levels, side effects caused by acupuncture, total scores on the insomnia severity index and traditional Chinese medicine symptom changes.This systematic review study will provide an evidence of acupuncture for PI.The study will give an explicit evidence to evaluate the effectiveness and side effects of acupuncture for PI.CRD42018092917. (...) Acupuncture for perimenopausal insomnia: A systematic review and meta-analysis protocol. Perimenopausal insomnia (PI) is one of the most common complaints in women. Acupuncture is used to treat PI increasingly considering its less side effect. The subject of this study is to explore the effectiveness and safety of acupuncture for PI.All the randomized controlled trials(RCT) literatures of acupuncture for PI will be searched in the databases of MEDLINE, Cochrane Library, Web of Science, EMBASE

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2018 Medicine

34. Risk of dementia in patients with primary insomnia: a nationwide population-based case-control study. (PubMed)

 years or older as the reference group. We excluded patients under 20 and those with depression, post-traumatic stress disorder, and/or sleep disorders caused by organic lesion(s), drugs, or alcohol. We used a Cox proportional hazards model to assess the primary insomnia on the risk of developing dementia after adjusting for sociodemographic characteristics and comorbidities.The primary insomnia cohort had a higher prevalence of diabetes, dyslipidemia, hypertension, coronary heart disease, chronic (...) Risk of dementia in patients with primary insomnia: a nationwide population-based case-control study. To investigate the association between primary insomnia and dementia using a Taiwanese population-based database.This case-control study involved a subset of Taiwan's National Health Insurance Research Database of reimbursement claims. We included 51,734 patients who were diagnosed with primary insomnia from 2002 to 2004 as the test group and 258,715 nonprimary insomnia participants aged 20

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2018 BMC Psychiatry

35. Age of Insomnia Onset Correlates with a Reversal of Default Mode Network and Supplementary Motor Cortex Connectivity (PubMed)

Age of Insomnia Onset Correlates with a Reversal of Default Mode Network and Supplementary Motor Cortex Connectivity Insomnia might occur as result of increased cognitive and physiological arousal caused by acute or long acting stressors and associated cognitive rumination. This might lead to alterations in brain connectivity patterns as those captured by functional connectivity fMRI analysis, leading to potential insight about primary insomnia (PI) pathophysiology as well as the impact of long (...) importantly early insomnia onset, seems to have a significant disruptive effect over the physiological negative correlation between DMN and SMA, a well-known fMRI marker of attention performance in humans. This suggests the need for more in-depth investigations on the prevention and treatment of connectivity changes and associated cognitive and psychological deficits in PI patients.

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2018 Neural plasticity

36. I Ching Balance Acupuncture Treatment of Migraines, Insomnia, and Depression in a Post-Ovariectomy Patient Receiving Hormone Replacement Therapy (PubMed)

, and was prescribed hormone replacement therapy. Deteriorating QoL caused her to seek acupuncture for migraines, insomnia, and depression. The outcomes sought for treatment of this case included intensity, duration, and frequency of migraines, insomnia, and depression, as well as her QoL. The outcome measures were estimated monthly throughout her treatment. Each was rated on a numeric scale of 0-10 (0 = "the lowest possible" and 10 = "the worst imaginable"). At baseline, the patient rated the intensity, duration (...) , and frequency of each complaint as 10. She was treated with 60-minute, I Ching Balance Acupuncture (ICBA) sessions once per week for 7 months. Results: This acupuncture treatment did not cause any adverse events, pain, or discomfort. Her migraines, insomnia, and depression decreased to a great extent. In addition, this patient reported considerable improvement in her QoL. The improvement in her QoL was inversely related to the intensity, duration, and frequency of her complaints throughout her acupuncture

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2018 Medical Acupuncture

37. Suanzaoren Formulae for Insomnia: Updated Clinical Evidence and Possible Mechanisms (PubMed)

Suanzaoren Formulae for Insomnia: Updated Clinical Evidence and Possible Mechanisms Insomnia disorder is a widespread and refractory disease. Semen Ziziphi Spinosae, Suanzaoren, a well-known Chinese herbal medicine, has been used for treating insomnia for thousands of years. Here, we aimed to assess the available evidence of Chinese herbal formulae that contains Suanzaoren (FSZR) for insomnia according to high-quality randomized controlled trials (RCTs) and reviewed their possible mechanisms (...) studies with 1,454 patients were identified. Meta-analysis of high-quality RCTs showed that FSZR monotherapy was superior to placebo (P < 0.01); FSZR plus Diazepam was superior to Diazepam alone (P < 0.05); there were mixed results comparing FSZR with Diazepam (P > 0.05 or P < 0.05). Furthermore, FSZR caused fewer side effects than that of Diazepam. Suanzaoren contains complex mixtures of phytochemicals including sanjoinine A, Jujuboside A, spinosin and other flavonoids, which has sedative

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2018 Frontiers in pharmacology

38. Assessment of Switching to Suvorexant versus the Use of Add-on Suvorexant in Combination with Benzodiazepine Receptor Agonists in Insomnia Patients: A Retrospective Study (PubMed)

Assessment of Switching to Suvorexant versus the Use of Add-on Suvorexant in Combination with Benzodiazepine Receptor Agonists in Insomnia Patients: A Retrospective Study Suvorexant is a novel hypnotic drug that does not interact with the conventional γ-aminobutyric acid (GABA)-A receptor. We investigated the method by which suvorexant was introduced in insomnia patients who were taking benzodiazepine receptor agonists (BzRA).This was a retrospective study. We extracted clinical data (...) for patients who were prescribed suvorexant and were already using BzRA. The patients were assigned to two groups, the switching and add-on groups. We assessed the suvorexant discontinuation rate at one month after the prescription of the drug.One hundred and nineteen patients were assigned to the switching group, and 109 were assigned to the add-on group. The add-on group exhibited a significantly higher all-cause discontinuation rate than the switching group (odds ratio, 2.7; 95% confidence interval, 1.5

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2018 Clinical Psychopharmacology and Neuroscience

39. Insomnia and Mild Cognitive Impairment (PubMed)

hypoglycemia, as a cause of middle insomnia, is the main focus of this case study. Other types of insomnia are also briefly reviewed. The management of insomnia is then discussed including sleep hygiene, the usefulness and potential drawbacks of dietary supplements, nonprescription over-the-counter preparations and prescription hypnotics. Sleep architecture is then briefly reviewed, emphasizing the importance of its integrity and the role of each sleep stage. (...) Insomnia and Mild Cognitive Impairment Insomnia is a common problem in older people, especially in patients with mild cognitive impairment (MCI) whose circadian rhythm is often compromised. Insomnia exerts such a toll on caregivers that it is frequently the primary reason for seeking to institutionalize their loved ones. Three different types of insomnia are recognized: sleep-onset or initial insomnia, sleep maintenance or middle insomnia, and early morning awakening or late insomnia. Nocturnal

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2018 Gerontology and geriatric medicine

40. Study of the Effects of HIRREM-SOP for Insomnia

Study of the Effects of HIRREM-SOP for Insomnia Study of the Effects of HIRREM-SOP for Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of the Effects of HIRREM-SOP for Insomnia The safety (...) by (Responsible Party): Wake Forest University Health Sciences Study Details Study Description Go to Brief Summary: Prior research studies have shown benefit for use of a technique called High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), to reduce symptoms of moderate to severe insomnia. HIRREM uses scalp sensors to monitor brain electrical activity, and software algorithms translate selected brain frequencies into audible tones in real time. Those tones (acoustic

2018 Clinical Trials

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