How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

23,907 results for

Insomnia Causes

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Obstructive Sleep Apnoea in Children and Adolescents With Ehlers-Danlos Syndrome

Additional relevant MeSH terms: Layout table for MeSH terms Syndrome Apnea Sleep Apnea Syndromes Sleep Apnea, Obstructive Ehlers-Danlos Syndrome Disease Pathologic Processes Respiration Disorders Respiratory Tract Diseases Signs and Symptoms, Respiratory Signs and Symptoms Sleep Disorders, Intrinsic Dyssomnias Sleep Wake Disorders Nervous System Diseases Hemostatic Disorders Vascular Diseases Cardiovascular Diseases Hemorrhagic Disorders Hematologic Diseases Skin Abnormalities Congenital Abnormalities (...) objective of this pioneer study is to assess the quality of life in children and adolescents in EDS in comparison to healthy children and adolescents. Condition or disease Intervention/treatment Ehler's Danlos Syndrome Obstructive Sleep Apnea Other: No intervention Detailed Description: Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility. EDS features

2016 Clinical Trials

182. Diagnosis of obstructive sleep apnea in adults: a clinical practice guideline from theAmerican College of Physicians. Full Text available with Trip Pro

Diagnosis of obstructive sleep apnea in adults: a clinical practice guideline from theAmerican College of Physicians. The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the diagnosis of obstructive sleep apnea in adults.This guideline is based on published literature on this topic that was identified by using MEDLINE (1966 through May 2013), the Cochrane Central Register of Controlled Trials, and the Cochrane (...) guidelines grading system.ACP recommends a sleep study for patients with unexplained daytime sleepiness. (Grade: weak recommendation, low-quality evidence).ACP recommends polysomnography for diagnostic testing in patients suspected of obstructive sleep apnea. ACP recommends portable sleep monitors in patients without serious comorbidities as an alternative to polysomnography when polysomnography is not available for diagnostic testing. (Grade: weak recommendation, moderate-quality evidence).

2014 Annals of Internal Medicine

183. Hetlioz (tasimelteon) - To treat non-24- hour sleep-wake disorder (?non-24?) in totally blind individuals. Non-24 is a chronic circadian rhythm (body clock) disorder in the blind that causes problems with the timing of sleep

Hetlioz (tasimelteon) - To treat non-24- hour sleep-wake disorder (?non-24?) in totally blind individuals. Non-24 is a chronic circadian rhythm (body clock) disorder in the blind that causes problems with the timing of sleep Drug Approval Package: Brand Name (Generic Name) NDA # Drug Approval Package U.S. Food & Drug Administration Search FDA Drug Approval Package - HETLIOZ (tasimelteon) 20 mg oral Capsules Company: Vanda Pharmaceuticals, Inc. Application No.: 205677 Approval Date: 1/31/2014

2014 FDA - Drug Approval Package

184. Obstructive Sleep Apnea Syndrome (Overview)

with obstructive sleep apnea in children. Previous Next: Pathophysiology Disordered breathing during sleep is a hallmark of . Breathing abnormalities include apnea (cessation of air flow) and hypopnea (decreased air flow). In addition, in contrast to adults, some children exhibit a variation of obstructive sleep apnea termed obstructive hypoventilation (OH). Children with obstructive hypoventilation demonstrate periods of hypercapnia that occur in the absence of discrete respiratory events that fulfill (...) HM, Liao D, Calhoun S, Fedok F, et al. Blood pressure associated with sleep-disordered breathing in a population sample of children. Hypertension . 2008 Nov. 52(5):841-6. . Marcus CL, Carroll JL, Koerner CB, Hamer A, Lutz J, Loughlin GM. Determinants of growth in children with the obstructive sleep apnea syndrome. J Pediatr . 1994 Oct. 125(4):556-62. . Bar A, Tarasiuk A, Segev Y, Phillip M, Tal A. The effect of adenotonsillectomy on serum insulin-like growth factor-I and growth in children

2014 eMedicine Pediatrics

185. Obstructive Sleep Apnea Syndrome (Treatment)

. Cognition, sleep and respiration in at-risk children treated for obstructive sleep apnoea. Eur Respir J . 2005 Feb. 25(2):336-42. . Bixler EO, Vgontzas AN, Lin HM, Liao D, Calhoun S, Fedok F, et al. Blood pressure associated with sleep-disordered breathing in a population sample of children. Hypertension . 2008 Nov. 52(5):841-6. . Marcus CL, Carroll JL, Koerner CB, Hamer A, Lutz J, Loughlin GM. Determinants of growth in children with the obstructive sleep apnea syndrome. J Pediatr . 1994 Oct. 125(4):556 (...) of obstructive sleep apnea, refer the patient to a pediatric otolaryngologist for adenotonsillectomy and take appropriate perioperative and postoperative precautions in higher-risk groups. When obesity is present, refer the patient to a nutritional intervention program. Similarly, pursue echocardiography and input from a pediatric cardiologist when pulmonary hypertension is clinically suspected. When craniofacial syndromes or neuromuscular disorders are the major cause of obstructive sleep apnea

2014 eMedicine Pediatrics

186. Obstructive Sleep Apnea Syndrome (Diagnosis)

with obstructive sleep apnea in children. Previous Next: Pathophysiology Disordered breathing during sleep is a hallmark of . Breathing abnormalities include apnea (cessation of air flow) and hypopnea (decreased air flow). In addition, in contrast to adults, some children exhibit a variation of obstructive sleep apnea termed obstructive hypoventilation (OH). Children with obstructive hypoventilation demonstrate periods of hypercapnia that occur in the absence of discrete respiratory events that fulfill (...) HM, Liao D, Calhoun S, Fedok F, et al. Blood pressure associated with sleep-disordered breathing in a population sample of children. Hypertension . 2008 Nov. 52(5):841-6. . Marcus CL, Carroll JL, Koerner CB, Hamer A, Lutz J, Loughlin GM. Determinants of growth in children with the obstructive sleep apnea syndrome. J Pediatr . 1994 Oct. 125(4):556-62. . Bar A, Tarasiuk A, Segev Y, Phillip M, Tal A. The effect of adenotonsillectomy on serum insulin-like growth factor-I and growth in children

2014 eMedicine Pediatrics

187. Obstructive Sleep Apnea Syndrome (Follow-up)

. Cognition, sleep and respiration in at-risk children treated for obstructive sleep apnoea. Eur Respir J . 2005 Feb. 25(2):336-42. . Bixler EO, Vgontzas AN, Lin HM, Liao D, Calhoun S, Fedok F, et al. Blood pressure associated with sleep-disordered breathing in a population sample of children. Hypertension . 2008 Nov. 52(5):841-6. . Marcus CL, Carroll JL, Koerner CB, Hamer A, Lutz J, Loughlin GM. Determinants of growth in children with the obstructive sleep apnea syndrome. J Pediatr . 1994 Oct. 125(4):556 (...) of obstructive sleep apnea, refer the patient to a pediatric otolaryngologist for adenotonsillectomy and take appropriate perioperative and postoperative precautions in higher-risk groups. When obesity is present, refer the patient to a nutritional intervention program. Similarly, pursue echocardiography and input from a pediatric cardiologist when pulmonary hypertension is clinically suspected. When craniofacial syndromes or neuromuscular disorders are the major cause of obstructive sleep apnea

2014 eMedicine Pediatrics

188. Obstructive sleep apnoea as a late complication after tracheostomy. (Abstract)

Obstructive sleep apnoea as a late complication after tracheostomy. Obstructive sleep apnoea occurs consequent to partial or complete upper airway obstruction, caused mostly by the collapse of upper airway musculature. Drug-induced sleep endoscopy represents the 'gold standard' in identifying the obstruction site, from the palatal level to laryngeal entry. Breathing impairment in sleep caused by the collapse of cervical trachea after previous tracheostomy has not yet been described (...) in the literature.This report presents two patients with severe obstructive sleep apnoea, in whom pre-operative drug-induced sleep endoscopy revealed upper airway and cervical trachea collapse at the level of previous tracheostomy.The female patient was successfully treated with resection of hypertrophic tissue of the tongue base via lateral pharyngectomy, and resection of the collapsed segment of the trachea with primary reconstruction of the trachea by end-to-end anastomosis. The male patient was recommended

2019 Journal of Laryngology & Otology

189. Perioperative considerations in the management of obstructive sleep apnoea. (Abstract)

Perioperative considerations in the management of obstructive sleep apnoea. Obstructive sleep apnoea (OSA) is characterised by repetitive compromise of the upper airway, causing impaired ventilation, sleep fragmentation, and daytime functional impairment. It is a heterogeneous condition encompassing different phenotypes. The prevalence of OSA among patients presenting for elective surgery is growing, largely attributable to an increase in age and obesity rates, and most patients remain

2019 Medical Journal of Australia

190. Use of bibloc and monobloc oral appliances in obstructive sleep apnoea: a multicentre, randomized, blinded, parallel-group equivalence trial. Full Text available with Trip Pro

Use of bibloc and monobloc oral appliances in obstructive sleep apnoea: a multicentre, randomized, blinded, parallel-group equivalence trial. The clinical benefit of bibloc over monobloc appliances in treating obstructive sleep apnoea (OSA) has not been evaluated in randomized trials. We hypothesized that the two types of appliances are equally effective in treating OSA.To compare the efficacy of monobloc versus bibloc appliances in a short-term perspective.In this multicentre, randomized (...) , blinded, controlled, parallel-group equivalence trial, patients with OSA were randomly assigned to use either a bibloc or a monobloc appliance. One-night respiratory polygraphy without respiratory support was performed at baseline, and participants were re-examined with the appliance in place at short-term follow-up. The primary outcome was the change in the apnoea-hypopnea index (AHI). An independent person prepared a randomization list and sealed envelopes. Evaluating dentist and the biomedical

2019 European journal of orthodontics Controlled trial quality: predicted high

191. Exposure to mild intermittent hypoxia increases loop gain and the arousal threshold in participants with obstructive sleep apnoea. (Abstract)

, and if present, administration of intermittent hypoxia during hours of wakefulness should be combined with continuous positive airway pressure treatment during sleep.We determined if exposure to mild intermittent hypoxia (MIH) causes an increase in loop gain (LG) and the arousal threshold (AT) during non-rapid eye movement (NREM) sleep. Male participants with obstructive sleep apnoea (apnoea-hypopnoea index > 5 events/h), matched for age, body mass index and race were divided into two groups (n = 13 in each (...) Exposure to mild intermittent hypoxia increases loop gain and the arousal threshold in participants with obstructive sleep apnoea. Repeated daily mild intermittent hypoxia has been endorsed as a therapy to promote the recovery of respiratory and limb motor dysfunction. One possible side-effect of this therapy is an increase in apnoeic event number and duration, which is particularly relevant to participants with motor disorders coupled with an increased incidence of sleep apnoea. In this study

2019 The Journal of physiology Controlled trial quality: uncertain

192. Treatment for Insomnia and Disrupted Sleep Behavior in Children and Adolescents with Autism Spectrum Disorder

Administration 14 GERD: gastroesophageal reflux disease 15 OSA: obstructive sleep apnea 16 OTC: over the counter 17 RMD: raw mean difference 18 SE: sleep efficiency 19 SOL: sleep onset latency 20 STS: Sound-to-Sleep 21 TST: time to sleep 22 WASO: wake after sleep onset 23 12 1 2 13 ABSTRACT 1 Objective: To review pharmacologic and nonpharmacologic strategies for treating sleep 2 disturbances in children and adolescents with autistic spectrum disorder (ASD) and to develop 3 recommendations for addressing (...) Weighted blankets 22 23 A 2-week crossover trial in children (5–16 years old) with ASD was Class II for actigraphy 1 outcomes (74% of randomized participants included in analysis) and Class III for sleep diary 2 outcomes. 36 Children had a =5-month history of sleep complaints in the absence of obstructive 3 sleep apnea (OSA), night terrors, or other sleep disorders (n=54–67, depending on arm). Sleep 4 onset latency was no shorter during weeks weighted blankets were used than during weeks 5 regular

2020 American Academy of Neurology

193. Oxidative stress in patients with obstructive sleep apnoea syndrome Full Text available with Trip Pro

Oxidative stress in patients with obstructive sleep apnoea syndrome Obstructive sleep apnoea syndrome (OSAS) is a disorder that leads to metabolic abnormalities and increased cardiovascular risk. The aim of this study was to identify early laboratory markers of cardiovascular disease through analysis of oxidative stress in normal subjects and patients with OSAS. A prospective study was designed to compare outcomes of oxidative stress laboratory tests in 20 adult patients with OSAS and a control (...) group of 20 normal subjects. Laboratory techniques for detecting and quantifying free radical damage must be targeted to assess the pro-oxidant component and the antioxidant in order to obtain an overall picture of oxidative balance. No statistical differences in age, sex distribution, or BMI were found between the two groups (p>0.05). There were significant differences in the apnoea/hypopnoea index (AHI) between OSAS patients and the control group (p<0.05). Statistically significant differences

2015 Acta Otorhinolaryngologica Italica

194. Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome

by (Responsible Party): Malcolm Kohler, University of Zurich Study Details Study Description Go to Brief Summary: Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility. EDS features such as genetically related cartilage defects, craniofacial abnormalities and increased pharyngeal collapsibility have been proposed to cause obstructive sleep apnoea (OSA (...) in EDS-patients (100) compared to a matched control group (100). The secondary objective of this pioneer study is to assess whether there is a relationship between OSA severity and aortic diame-ter/craniofacial abnormalities in EDS patients. Condition or disease Ehlers-Danlos Syndrome Obstructive Sleep Apnea Detailed Description: Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin

2015 Clinical Trials

195. Role of common hypnotics on the phenotypic causes of obstructive sleep apnoea: paradoxical effects of zolpidem. Full Text available with Trip Pro

Role of common hypnotics on the phenotypic causes of obstructive sleep apnoea: paradoxical effects of zolpidem. Hypnotics are contraindicated in obstructive sleep apnoea (OSA) because of concerns of pharyngeal muscle relaxation and delayed arousal worsening hypoxaemia. However, human data are lacking. This study aimed to determine the effects of three common hypnotics on the respiratory arousal threshold, genioglossus muscle responsiveness and upper airway collapsibility during sleep.21 (...) individuals with and without OSA (18-65 years) completed 84 detailed sleep studies after receiving temazepam (10 mg), zolpidem (10 mg), zopiclone (7.5 mg) and placebo on four occasions in a randomised, double-blind, placebo-controlled, crossover trial (ACTRN12612001004853).The arousal threshold increased with zolpidem and zopiclone versus placebo (mean±sd -18.3±10 and -19.1±9 versus -14.6±7 cmH2O; p=0.02 and p<0.001) but not with temazepam (-16.8±9 cmH2O; p=0.17). Genioglossus muscle activity during

2017 European Respiratory Journal Controlled trial quality: predicted high

196. Retropharyngeal lipoma causing obstructive sleep apnoea Full Text available with Trip Pro

Retropharyngeal lipoma causing obstructive sleep apnoea We present the case of a middle-aged man whose obstructive sleep apnoea (OSA) was caused by a retropharyngeal lipoma, with complete resolution after transoral excision. Lipomas causing OSA are rare, and this represents the seventh reported case in the literature.

2017 Respirology case reports

197. Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome

apnea syndrome Continuous positive airway pressure sham or placebo CPAP Additional relevant MeSH terms: Layout table for MeSH terms Syndrome Apnea Sleep Apnea Syndromes Sleep Apnea, Obstructive Down Syndrome Disease Pathologic Processes Respiration Disorders Respiratory Tract Diseases Signs and Symptoms, Respiratory Signs and Symptoms Sleep Disorders, Intrinsic Dyssomnias Sleep Wake Disorders Nervous System Diseases Intellectual Disability Neurobehavioral Manifestations Neurologic Manifestations (...) : February 8, 2016 Last Update Posted : February 8, 2016 Sponsor: Children's Hospital of Philadelphia Information provided by (Responsible Party): Children's Hospital of Philadelphia Study Details Study Description Go to Brief Summary: Many individuals with Down syndrome (DS) have breathing problems during sleep. This is called obstructive sleep apnea syndrome (OSAS). OSAS is very common in individuals with Down syndrome because of the shape of their face and tongue and because of their low muscle tone

2013 Clinical Trials

198. Laryngeal pathologies as an etiologic factor of obstructive sleep apnea syndrome in children. (Abstract)

Laryngeal pathologies as an etiologic factor of obstructive sleep apnea syndrome in children. Obstructive sleep apnea syndrome is a chronic condition of airway obstruction, common in children, with known clinical consequences. The etiology of OSAS in children stems from a combination of obstructing structural factors and neuromotor factors. In children, tonsilar hypertrophy accounts for this condition in most cases, however, in about 20% of the cases, other causes are involved (...) . For the treatment of apnea in children, adenotonsillectomy is the most commonly performed procedure, though we should indicate the treatment according to its underlying cause. The aim of this paper is to highlight other possible apnea etiologies, contributing to appropriate diagnosis and treatment. We present two cases of patients with apnea of unusual origin: one of respiratory dystonia and another of supraglottic stenosis as the causative factor of obstructive sleep apnea. In conclusion, we emphasize the need

2013 International Journal of Pediatric Otorhinolaryngology

199. The effects of mometasone furoate and desloratadine in obstructive sleep apnea syndrome patients with allergic rhinitis. (Abstract)

The effects of mometasone furoate and desloratadine in obstructive sleep apnea syndrome patients with allergic rhinitis. Allergic rhinitis (AR) and obstructive sleep apnea syndrome (OSAS) are worldwide prevalent diseases. These diseases impair patient quality of life. The aim of this study was to investigate and compare the efficacy of treatment of AR on OSAS by objective and subjective methods.The study group was composed of 80 OSAS patients with AR between the ages of 30 and 50 years (...) . The patients were admitted with the complaint of snoring, and they were asked about AR-related symptoms (nasal discharge, nasal itching, sneeze, and nasal obstruction). Daytime somnolence was measured by the Epworth sleepiness scale (ESS). Sleep parameters on polysomnography tests before and after treatment were compared, and the effects of different AR treatment protocols on sleep quality were evaluated.When pretreatment and posttreatment apnea-hypopnea index (AHI) values of the groups were compared

2013 American journal of rhinology & allergy

200. Critical review: CPAP and weight management of obstructive sleep apnea cardiovascular co-morbidities. (Abstract)

Critical review: CPAP and weight management of obstructive sleep apnea cardiovascular co-morbidities. The cardiovascular co-morbidities of obstructive sleep apnea (OSA) are similar to those of obesity. Cardiovascular co-morbidities often are the cause of adverse outcomes in overweight/obese OSA patients. Continuous positive airway pressure (CPAP) therapy resolves the symptoms of OSA, but may, or may not lead to improvement of a given cardiovascular co-morbidity. The impact of CPAP

2016 Sleep medicine reviews

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>