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Insight and Judgement

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102. Canadian Cardiovascular Society/Canadian Heart Rhythm Society Joint Position Statement on the Cardiovascular Screening of Competitive Athletes

of the athletes were deemed asymptomatic. x 18 Finocchiaro, G., Papadakis, M., Robertus, J.L. et al. Etiology of sudden death in sports: insights from a United Kingdom regional registry. J Am Coll Cardiol . 2016 ; 67 : 2108–2115 Several studies have included athletes who screened “positive” for conditions associated with no additional risk of SCD (ie, isolated bicuspid aortic valve) and were subsequently cleared for participation. x 15 Tischer, S.G., Mattsson, N., Storgaard, M. et al. Results of voluntary (...) in Switzerland: implications for routine ECG screening. Br J Sports Med . 2014 ; 48 : 1157–1161 The reported low sensitivity of history/questionnaire is not surprising because 70%-80% of SCD occurs as the first manifestation of an underlying cardiac disease. x 18 Finocchiaro, G., Papadakis, M., Robertus, J.L. et al. Etiology of sudden death in sports: insights from a United Kingdom regional registry. J Am Coll Cardiol . 2016 ; 67 : 2108–2115 , x 21 Corrado, D., Basso, C., Schiavon, M., and Thiene, G

2018 Canadian Cardiovascular Society

103. Mindfulness-based stress reduction (MBSR) for improving health, quality of life and social functioning in adults

as the skill to non-judgementally observe sensations, thoughts, emotions and the environment, while encouraging openness, curiosity and acceptance. A Program to strengthen this skill was developed at the University of Massachusetts Medical Center in 1979 as an intervention to relieve stress, cope with illness and promote health. It is now being offered at many health care facilities and in other settings around the world. Target groups are typically people with chronic somatic or mental illnesses (...) experiences in each moment. The intervention derives its roots from ancient Buddhist practices of Samatha (concentration) and Vipassana (insight) meditation and yoga exercises, but has been adapted and is described in Western terminology free from religious affiliation. In addition to the mindfulness practice, there are teachings (and reflections) on stress, stress management, and how to apply mindfulness to interpersonal communication and everyday situations. In each session group members reflect

2017 Campbell Collaboration

105. Cancer Australia Annual Report 2016-17

in delivering on its outcomes and objectives. I would like to especially thank the Chair of the Advisory Council, Professor Robert Thomas OAM, for his ongoing support and guidance. 5 Overview I also extend my thanks to the members of Cancer Australia’s strategic and program advisory groups and the members of the agency’s various project steering committees, working groups and assessment panels who provide important guidance to Cancer Australia. The insights they contribute help support the delivery (...) Australia’s vision and mission and their meaningful contribution to the Council’s deliberations. The Council acknowledges contribution of the Hon Greg Hunt MP , Minister for Health and Minister for Sport, for his support during 2016–17 and the interest he has shown in Cancer Australia’s work and achievements during the year. On behalf of the Council, I acknowledge and commend Cancer Australia’s CEO, Dr Helen Zorbas and thank her for her insightful leadership. I also commend the agency’s senior management

2017 Cancer Australia

107. Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine

and supporting documents are available at: http://sydney.edu.au/medicine/cdpc/resources/deprescribing-guidelines.php Disclaimer This document is a general guide to be followed subject to the clinician’s judgement and the person’s preference in each individual case. The guideline is designed to provide information to assist decision making and is based on the best evidence available at the time of developing this publication. Publication approval The guideline recommendations on pages 7-9 of this document (...) ) and a reasonable judgement of the limited potential for harm in a carefully monitored trial of discontinuation. This document is a general guide. Implementation of recommendations should only be conducted by qualified/trained personnel in consultation with appropriate parties (such as the prescriber, family, nurses and care staff). The people involved in these parties for consultation will vary by setting and should be considered in the local context, considering the scopes of practice of healthcare

2018 Clinical Practice Guidelines Portal

108. Building Evaluation Capacity

). The internal scan was used to understand the level of evaluation capacity and identify evaluation resource and support needs. The external scan provided insight into the function and form that support high evaluation capacity within public health organizations. Program evaluation is routine practice at the ROP–PH. Between 2011 and 2016, staff completed 75 program evaluations. (3) Despite this active involvement, evaluation capacity could be strengthened. Staff primarily conduct process evaluations (...) ; and 10 ? the reputability of the publication source: peer-reviewed, evaluation journal. The appraisal excluded three papers. It was not appropriate to critically appraise the methodology of the papers. No prescribed method exists for developing conceptual models; they often evolve over time from the insights of researchers. (5) Each ECB conceptual model was individually analyzed and critiqued using an adaptation of Fawcett’s Framework for Analyzing and Evaluating Conceptual Models in Nursing (see

2018 Peel Health Library

109. Mental health care in the perinatal period: Australian clinical practice guideline

of that reproduction. Apart from any use as permitted under the Copyright Act 1968 and this notice, all other rights are expressly reserved. Inquiries Requests and inquiries concerning reproduction and rights should be sent to Communications Branch, Department of Health, GPO Box 9848, Canberra ACT 2601 or copyright@health.gov.au Disclaimer This is a general guide to appropriate practice, to be followed subject to the relevant clinician’s judgement in each individual case. COPE has taken all reasonable steps

2018 Clinical Practice Guidelines Portal

111. Chimeric Antigen Receptor T-Cell Therapy for B-Cell Cancers: Effectiveness and Value

, defined as more than $10,000 in healthcare company stock or more than $5,000 in honoraria or consultancies during the previous year from health care manufacturers or insurers ©Institute for Clinical and Economic Review, 2018 Page v Final Evidence Report – CAR-T Therapies for B-Cell Cancers Return to Table of Contents Table of Contents Executive Summary ES1 1. Introduction 1 1.1 Background 1 1.2 Scope of the Assessment 4 1.3 Definitions 7 1.4 Insights Gained from Discussions with Patients and Patient (...) month post- infusion. 10,16 Insights Gained from Discussions with Patients and Patient Groups Several themes emerged from our discussion with patients and patient groups. One was hope – CAR-T therapy represented hope for a cure in patients who had run out of treatment options. They were encouraged by the high initial response rates seen in the clinical trials. In addition, they hoped that CAR-T therapy would be less toxic than chemoradiation and stem cell transplant (SCT): no hair loss, mucositis

2018 California Technology Assessment Forum

112. BSG and UKPBC primary biliary cholangitis treatment and management guidelines

is thought to be part of the underlying disease process in PBC. Clinical judgement should be used as to whether the rare concern about the possibility of haematological or other forms of malignant disease is sufficient to warrant biopsy exclusion on a case-by-case basis. In end-stage PBC, imaging to screen for the complications of cirrhosis should be routine as for cirrhosis of other aetiology. Histological features of pBC Histopathological evaluation of liver biopsy tissue in PBC can be challenging

2018 British Society of Gastroenterology

113. WHO recommendations: non-clinical interventions to reduce unnecessary caesarean sections

studies. Judgements about values, acceptability, equity, resource implications and feasibility of interventions were informed by three systematic reviews of 49 qualitative studies. The certainty of evidence on safety and effectiveness outcomes was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE). Confidence in the qualitative findings was assessed using Confidence in the Evidence from Reviews of Qualitative research (CERQual). The framework for Developing

2018 World Health Organisation Guidelines

114. What constitutes an effective and efficient package of services for the prevention, diagnosis, treatment and care of tuberculosis among refugees and migrants in the WHO European Region? Themed issues on migration and health

from persecution in his or her country of origin due to factors such as race, religion or politics (26,27). Refugee: an individual who has been granted asylum or has been successful in overturning a previous judgement that ruled against an asylum application (26,28). Political instability: A unified, whole-of-government approach to noncommunicable disease prevention is the best way to ensure sustained and stable funding, resources and public health and research priorities (4). Therefore, political (...) of an appropriate confidential space • limited funding • poor communication between services and laboratories • lack of coordination across services, and • time constraints. A number of facilitators to improving screening uptake in migrant communities have been identified: • well-trained and dedicated screening staff: • culturally sensitive and appropriate services • trust and respect for the judgement of staff • interviews conducted by a health care worker in a migrant's native language (47), and • language

2018 WHO Health Evidence Network

116. Chimeric Antigen Receptor T-Cell Therapy for B-Cell Cancers: Effectiveness and Value

as more than $10,000 in healthcare company stock or more than $5,000 in honoraria or consultancies during the previous year from health care manufacturers or insurers ©Institute for Clinical and Economic Review, 2018 Page v Evidence Report – CAR-T Therapies for B-Cell Cancers Return to Table of Contents Table of Contents Executive Summary ES1 1. Introduction 1 1.1 Background 1 1.2 Scope of the Assessment 4 1.3 Definitions 7 1.4 Insights Gained from Discussions with Patients and Patient Groups 10 1.5 (...) the preparation and administration of the CAR-T therapy as well as management of side effects. Novartis has entered into an outcomes-based pricing arrangement with the Centers for Medicare and Medicaid Services (CMS) in which it appears that payment will be provided only for pediatric and young adult patients who respond to treatment with tisagenlecleucel at the end of the first month post-infusion. 10 Insights Gained from Discussions with Patients and Patient Groups Several themes emerged from our discussion

2018 California Technology Assessment Forum

118. Urban disaster risk governance: A systematic review

to address urban disaster risk issues. One of the main objectives of this paper is to map the emerging literature on urban disaster risk governance in order to gain insight into how governance, both “good” and “bad”, informs disaster risk. The ambition, although beyond what was possible in this paper, was to draw out learning across-contexts on what promotes and drives improvements in disaster risk governance, particularly in urban areas where there are often established institutions and networks, both (...) land or increased density, there is a risk of greater exposure and vulnerability of people and assets to natural hazards. For example, urban expansion in a number of developing country cities has led to the growth of informal settlements on areas prone to seasonal flooding (Dodman et al. 2013). A frequent policy response to this is risk-sensitive land-use planning. The second level of this review will draw out the wider urban risk governance literature insights on land-use planning and local policy

2017 EPPI Centre

119. Routine investigation and monitoring of adult HIV-1-positive individuals (2019 interim update)

of the majority of the potential sources of bias. Grade C evidence is low-quality evidence from controlled trials with several serious limitations, or observational studies with limited evidence on effects and exclusion of most potential sources of bias. Grade D evidence is based only on case studies, expert judgement or observational studies with inconsistent effects and a potential for substantial bias, such that there can be little confidence in the effect estimate. In addition to graded recommendations (...) , we have included good practice points (GPP), which are recommendations based on the clinical judgement and experience of the working group. GPPs emphasise an area of important clinical practice for which there is not, nor is there likely to be, any significant research evidence. They address an aspect of treatment and care that is regarded as such sound clinical practice that healthcare professionals are unlikely to question it and where the alternative recommendation is deemed unacceptable

2019 British HIV Association

120. Position Paper for the Treatment of Nightmare Disorder in Adults

evidence and clinical judgement of the task force. Positions of “may be used” indicate that the evidence or expert consensus is less clear, either in favor or against the use of a treatment option. The interventions listed below are in alphabetical order within the position statements rather than clinical preference: this is not meant to be instructive of the order in which interventions should be used. Position Statements: The following therapy is recommended for the treatment of PTSD-associated (...) judgement of the task force regarding the treatment of PTSD-associated nightmares and nightmares without a clear etiology (ie, nightmare disorder). POSITION STATEMENTS The AASM supports the following positions on the treatment of nightmare disorder in adults. Note that the interventions are listed in alphabetical order within the position statements. The order in which they are listed is not meant to be instructive of the order in which interventions should be used. Behavioral and Psychological

2018 American Academy of Sleep Medicine

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