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Hysterectomy

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101. Genetic polymorphisms and prediction of chronic post-surgical pain after hysterectomy-a subgroup analysis of a multicenter cohort study. Full Text available with Trip Pro

Genetic polymorphisms and prediction of chronic post-surgical pain after hysterectomy-a subgroup analysis of a multicenter cohort study. Chronic post-surgical pain (CPSP) is a serious problem. Clinical and psychological variables have not been able to explain all observed variance in prevalence and severity of CPSP. The first objective is to determine the association between genetic polymorphisms and the prevalence of CPSP after hysterectomy. The second objective is to analyze (...) if the implementation of genetic polymorphisms into a previously performed clinical and psychological predictor analysis on the development of CPSP after hysterectomy will improve its discriminatory power.A prospective multicenter cohort study was performed in patients undergoing hysterectomy for benign indication. Clinical and psychological variables were collected by questionnaires in the week before surgery, post-operatively up to day 4, 3 and 12 months after hysterectomy. Blood was collected and 16

2019 Acta Anaesthesiologica Scandinavica

102. Detailed Morphologic and Immunohistochemical Characterization of Myomectomy and Hysterectomy Specimens From Women With Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome (HLRCC). (Abstract)

Detailed Morphologic and Immunohistochemical Characterization of Myomectomy and Hysterectomy Specimens From Women With Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome (HLRCC). Hereditary leiomyomatosis and renal cell carcinoma syndrome (HLRCC), caused by a germline mutation in the fumarate hydratase (FH) gene, predisposes patients to uterine and cutaneous smooth muscle tumors and an aggressive type of renal cell carcinoma. Almost all women with HLRCC develop symptomatic uterine (...) presented with symptomatic uterine fibroids and underwent myomectomy (age 24 to 36 y), followed by hysterectomy in 2 patients (age 31 and 40 y). Specimens showed conventional leiomyomas, cellular leiomyomas and leiomyomas with bizarre nuclei. FH-d morphology was present in leiomyomas from all patients and was typically observed as a diffuse finding in the majority of slides across different leiomyoma types. FH-d morphology was absent in some leiomyoma sections from one patient and the morphologic

2019 American Journal of Surgical Pathology

103. Outpatient versus inpatient total laparoscopic hysterectomy: a randomized controlled trial. Full Text available with Trip Pro

Outpatient versus inpatient total laparoscopic hysterectomy: a randomized controlled trial. The objective of the study was to investigate whether outpatient total laparoscopic hysterectomy (TLH) could be performed as a routine without compromising patient satisfaction. The main outcomes were patient satisfaction with length of hospital stay, quality of life, complications and readmissions, and time to return to work.A non-blinded prospective randomized controlled trial (Canadian Task Force

2019 Acta Obstetricia et Gynecologica Scandinavica Controlled trial quality: predicted high

104. Sexual-, bladder-, bowel and ovarian function one year after robot-assisted radical hysterectomy for early stage cervical cancer. (Abstract)

Sexual-, bladder-, bowel and ovarian function one year after robot-assisted radical hysterectomy for early stage cervical cancer. Surgery by open radical hysterectomy for cervical cancer is associated with sexual dysfunction as well as lymphedema and bladder problems. Our aim was to assess the impact of robot-assisted laparoscopic radical hysterectomy (RRH) with pelvic lymphadenectomy, for early stage cervical cancer on sexual-, bowel-, bladder- and lymphatic function and to measure ovarian

2019 Acta Obstetricia et Gynecologica Scandinavica

105. Peritoneal contamination with ICG stained cervical secretion as surrogate for potential cervical cancer tumor cell dissemination. A proof-of-principle study for laparoscopic hysterectomy. (Abstract)

Peritoneal contamination with ICG stained cervical secretion as surrogate for potential cervical cancer tumor cell dissemination. A proof-of-principle study for laparoscopic hysterectomy. Intracorporal colpotomy during radical hysterectomy for cervical cancer is discussed to be a risk factor for peritoneal dissemination of tumor cells. It might lead to increased recurrence rates after laparoscopic radical hysterectomy compared to abdominal hysterectomy as shown by the recent LACC study. Data (...) on the frequency or mechanisms of peritoneal contamination are missing. We aimed to analyze peritoneal contamination of cervical secretion during intracorporal colpotomy with a novel indocyaningreen (ICG) -based technique.In this prospective proof-of-principle study, patients undergoing routine laparoscopic or robot-assisted hysterectomy were included. ICG was specifically applied to the cervical surface and routine surgery was performed. During colpotomy pictures under white and fluorescence light were taken

2019 Acta Obstetricia et Gynecologica Scandinavica

106. Safety of same-day discharge for minimally invasive hysterectomy for endometrial cancer. (Abstract)

Safety of same-day discharge for minimally invasive hysterectomy for endometrial cancer. Same-day discharge is becoming increasingly common for women who undergo minimally invasive hysterectomy. For women with endometrial cancer, there are limited data to describe the safety of same-day discharge.To examine trends and outcomes of same-day discharge for women with endometrial cancer who underwent minimally invasive hysterectomy.The National Surgical Quality Improvement Program database was used (...) to identify patients who underwent minimally invasive hysterectomy based for endometrial cancer from 2011 to 2016. The cohort was limited to women discharged on the day of surgery/postoperative day 0 or postoperative day 1. Multivariable models were used to examine clinical, demographic, and procedural characteristics associated with discharge on postoperative day 0. Multivariable models also were developed to examine the association between same-day discharge and readmission.A total of 17,935 patients

2019 American Journal of Obstetrics and Gynecology

107. Assessing Endometrial Cancer Risk Among US Women: Long-Term Trends using Hysterectomy-Adjusted Analysis. (Abstract)

Assessing Endometrial Cancer Risk Among US Women: Long-Term Trends using Hysterectomy-Adjusted Analysis. Commonly reported incidence rates for endometrial cancer (EC) fail to take into account both the large number of hysterectomies performed each year and the dynamic change in hysterectomy rate over the past decade. Large racial differences in pre-menopausal hysterectomy rates between Black and White women in the US likely affect calculation of race-based risk.To determine how the long-term (...) trends in Black-White differences in EC incidence and histology type have changed over time for women at risk.Using longitudinal Surveillance, Epidemiology, and End Results data from 1997 to 2014 and state-level hysterectomy prevalence from the Behavioral Risk Factor Surveillance System, we calculated hysterectomy-adjusted incidence rates of endometrial cancer and the proportion of high vs. low-risk EC, by race, over time.In women over 50 who have not had a hysterectomy, EC incidence is 87/100,000

2019 American Journal of Obstetrics and Gynecology

108. Association of Radical Hysterectomy Surgical Volume and Survival for Early-Stage Cervical Cancer. (Abstract)

Association of Radical Hysterectomy Surgical Volume and Survival for Early-Stage Cervical Cancer. To examine the association between surgical volume and survival of women with early-stage cervical cancer who underwent radical hysterectomy.This is a nationwide multicenter retrospective study examining consecutive women with clinical stage IB1-IIB cervical cancer who underwent radical hysterectomy and pelvic lymphadenectomy from 2004 to 2008 (N=5,964). The surgical volume per site over the 5-year (...) an independent prognostic factor for decreased recurrence (adjusted HR 0.69, 95% CI 0.57-0.84, P<.001) and all-cause mortality (adjusted HR 0.75, 95% CI 0.59-0.95, P=.016) compared with surgery at mid- and low-volume centers on multivariable analysis.Hospital volume for radical hysterectomy may be a prognostic factor for early-stage cervical cancer. Surgery at high-volume centers is associated with decreased local recurrence risk and improved survival.

2019 Obstetrics and Gynecology

109. What Is New in Hysterectomy for Benign Gynecologic Disorders?: Best Articles From the Past Year. (Abstract)

What Is New in Hysterectomy for Benign Gynecologic Disorders?: Best Articles From the Past Year. This month we focus on current research in hysterectomy for benign gynecologic disorders. Dr. Famuyide discusses four recent publications, which are concluded with a "bottom-line" that is the take-home message. A complete reference for each can be found on Box 1 on this page along with direct links to abstracts.

2019 Obstetrics and Gynecology

110. No survival difference between robotic and open radical hysterectomy for women with early-stage cervical cancer: results from a nationwide population-based cohort study. Full Text available with Trip Pro

No survival difference between robotic and open radical hysterectomy for women with early-stage cervical cancer: results from a nationwide population-based cohort study. The aim of the study was to compare overall survival (OS) and disease-free survival (DFS) after open and robotic radical hysterectomy for early-stage cervical cancer.This was a nationwide population-based cohort study on all women with cervical cancer stage IA1-IB of squamous, adenocarcinoma or adenosquamous histological (...) subtypes, from January 2011 to December 2017, for whom radical hysterectomy was performed. The Swedish Quality Register of Gynaecologic Cancer was used for identification. To ensure quality and conformity of data and to disclose patients not yet registered, hospital registries were reviewed and validated. Cox and propensity score regression analysis and univariable and multivariable regression analysis were performed in regard to OS and DFS.There were 864 women (236 open and 628 robotic) included

2019 European Journal of Cancer

111. Prevalence, Characteristics, and Risk Factors of Occult Uterine Cancer in Presumed Benign Hysterectomy. (Abstract)

Prevalence, Characteristics, and Risk Factors of Occult Uterine Cancer in Presumed Benign Hysterectomy. Occult uterine cancer at the time of benign hysterectomy poses unique challenges in patient care. There is large variability and uncertainty in estimated risk of occult uterine cancer in the literature and prior research often did not differentiate/include all subtypes.To thoroughly examine the prevalence of occult uterine cancer in a large population-based sample of women undergoing (...) hysterectomy for presumed benign indications and to identify associated risk factors.Using the New York Statewide Planning and Research Cooperative System database, we identified 229,536 adult women who underwent an inpatient or outpatient hysterectomy for benign indications in 10/1/2003-12/31/2013 at civilian hospitals and ambulatory surgery centers throughout the State. Diagnosis of corpus uteri cancer within 28 days after the index hysterectomy was determined using linked state cancer registry data. We

2019 American Journal of Obstetrics and Gynecology

112. Comparative outcomes between robotic and abdominal radical hysterectomy for IB1 cervical cancer: Results from a single high volume institution. Full Text available with Trip Pro

Comparative outcomes between robotic and abdominal radical hysterectomy for IB1 cervical cancer: Results from a single high volume institution. To compare the perioperative morbidity and survival between abdominal radical hysterectomy (ARH) and robotic radical hysterectomy (RRH).A retrospective cohort of patients undergoing radical hysterectomy for cervical cancer from 2010 to 2016 was identified. Patients with stage IB1 cervical cancer were included and were grouped by ARH vs. RRH. Tumor

2019 Gynecologic Oncology

113. Opioid use after laparoscopic hysterectomy: prescriptions, patient use, and a predictive calculator. (Abstract)

Opioid use after laparoscopic hysterectomy: prescriptions, patient use, and a predictive calculator. In the setting of America's opioid epidemic, judicious postoperative opioid prescribing is important. Gynecologists lack standard guidelines about postoperative opioid prescriptions.The objectives of the study were to describe opioid prescribing practices by a group of minimally invasive gynecologic surgeons, to measure postoperative opioid use after minimally invasive hysterectomy (...) , and to identify preoperative factors that could predict whether a patient will be a low or high postoperative opioid user.This was a prospective survey-based study including 125 women undergoing laparoscopic hysterectomy for benign indications at 2 community teaching hospitals. Patients were preoperatively surveyed about demographics, past medical history, and current and expected pain scores and were screened for anxiety, depression, and pain catastrophizing. At 1 and 2 weeks after surgery, patients were

2019 American Journal of Obstetrics and Gynecology

114. Role of preoperative pregabalin in reducing inhalational anaesthetic requirements in abdominal hysterectomy: randomized controlled trial. (Abstract)

Role of preoperative pregabalin in reducing inhalational anaesthetic requirements in abdominal hysterectomy: randomized controlled trial. Preoperative oral pregabalin controls postoperative pain & decreases anesthetic requirements in total intravenous anesthesia. In this study, we hypothesized that preoperative pregabalin reduces inhaled isoflurane requirements.We have investigated the effectiveness of preoperative oral pregabalin 150 mg in women undergoing elective open total abdominal (...) hysterectomy under general anesthesia. A prospective, randomized, double-blind, controlled study was conducted in a university hospital. The study included 50 women (18-60 yrs.), ASA I or II, admitted for abdominal hysterectomy under general anesthesia. Exclusion criteria were allergy to pregabalin; calcium channel blockers, antiepileptic drugs, antidepressant drugs, any analgesics, sedatives, or oral hypoglycemic agents. Patients were randomized into 2 groups; Pregabalin group received oral pregabalin 150

2019 Minerva anestesiologica

115. Post-hysterectomy rare collision vulva tumor with long-term human papilloma virus infection composed of squamous cell carcinoma of the labia major and adenosquamous carcinoma of bartholin gland: A case report. Full Text available with Trip Pro

Post-hysterectomy rare collision vulva tumor with long-term human papilloma virus infection composed of squamous cell carcinoma of the labia major and adenosquamous carcinoma of bartholin gland: A case report. Post-hysterectomy collision tumors of the vulva has rarely been reported. Though long-term HPV infection may induce vulva tumor, but the relationship between HPV infection and collision vulva tumor is not clear. And there are no clear rules of the post-hysterectomy cancer surveillance (...) for human papilloma virus (HPV) long-term infections. So here we first report a case of post-hysterectomy rare collision vulva tumor with long-term HPV infection composed of squamous cell carcinoma of the labia major and adenosquamous carcinoma of bartholin gland and hope to bring new direction to our future research.A 48-year-old woman with long-term HPV infection, 3 years after hysterectomy, gravida 3, para 2, was admitted to our hospital with complaints of a 4-month history of an itching vulva

2019 Medicine

116. Palonosetron versus ondansetron for prevention of nausea and vomiting after total abdominal hysterectomy under spinal anesthesia with intrathecal morphine: a double-blind, randomized controlled trial. Full Text available with Trip Pro

Palonosetron versus ondansetron for prevention of nausea and vomiting after total abdominal hysterectomy under spinal anesthesia with intrathecal morphine: a double-blind, randomized controlled trial. Hysterectomy is a widely performed surgery and neuraxial anesthesia with intrathecal morphine provides superior quality of recovery. Postoperative nausea and vomiting (PONV) is a frequent problem with intrathecal morphine use. Although palonosetron is effective for prevention of PONV after general (...) anesthesia, its efficacy after neuraxial anesthesia has not been established. This study was conducted to compare the use of palonosetron with ondansetron for PONV prophylaxis in patients at a high risk of PONV during total abdominal hysterectomy (TAH) under spinal anesthesia with intrathecal morphine.This prospective, randomized double-blind study conducted at São Rafael Hospital involved 140 American Society of Anesthesiologists physical status I or II women who underwent TAH under spinal anesthesia

2019 BMC Anesthesiology Controlled trial quality: uncertain

117. Outcome of adjuvant radiotherapy after total hysterectomy in patients with uterine leiomyosarcoma or carcinosarcoma: a SEER-based study. Full Text available with Trip Pro

Outcome of adjuvant radiotherapy after total hysterectomy in patients with uterine leiomyosarcoma or carcinosarcoma: a SEER-based study. The clinical impact of adjuvant radiotherapy on uterine sarcoma is unclear, and may depend on the histological type. Hence, the aim of this study was to evaluate clinical outcomes of adjuvant radiotherapy after total hysterectomy in patients with leiomyosarcoma or carcinosarcoma.Data were obtained from the Surveillance, Epidemiology, and End Results (SEER

2019 BMC Cancer

118. Clinical analysis of high risk factors for pelvic malignant tumors after hysterectomy for benign diseases. Full Text available with Trip Pro

Clinical analysis of high risk factors for pelvic malignant tumors after hysterectomy for benign diseases. To analyze the clinicopathological characteristics of pelvic masses after hysterectomy for benign diseases, and to analyze the related factors of benign and malignant pelvic masses.This study retrospectively analyzed the patients undergone reoperation for pelvic mass subsequently to hysterectomy for benign disease from January 2012 to December 2016 in Peking Union Medical College (...) Hospital.A total of 247 patients were enrolled in this study, of which 34.01% were diagnosed with malignant tumors, and 65.99% benign tumors. Comparing the clinicopathological data of patients with benign and malignant pelvic masses, significant differences were found between the 2 groups with regard to their ages of having hysterectomy and pelvic mass resection, and the time intervals between the onset of pelvic mass and hysterectomy. In addition, patients with malignant masses tended to complain

2019 Medicine

119. Reducing Blood Loss During Abdominal Hysterectomy with Intravenous Versus Topical Tranexamic Acid: A Double-Blind Randomized Controlled Trial. (Abstract)

Reducing Blood Loss During Abdominal Hysterectomy with Intravenous Versus Topical Tranexamic Acid: A Double-Blind Randomized Controlled Trial. To assess the effect of intravenous versus topical tranexamic acid in reducing intraoperative and postoperative blood loss in women with abdominal hysterectomy.The study was a randomized double-blind placebo-controlled trial, carried out in a tertiary university hospital in Egypt, from November 2015 to October 2017. A total of 129 women undergoing (...) abdominal hysterectomy for benign etiology were randomly assigned to three groups: Group I [43 patients received 110 ml normal saline IV just before skin in scion], Group II [43 patients received 1 g tranexamic acid in 100 ml saline IV just before skin in scion], and Group III [43 patients received 2 g topical tranexamic acid applied intra-abdominal after hysterectomy]. The primary outcome was intraoperative, postoperative, and all blood loss estimation.Both Group II (IV tranexamic acid) and Group III

2019 Journal of obstetrics and gynaecology of India Controlled trial quality: predicted high

120. Effect of the EX-PLISSIT model on sexual function and sexual quality of life among women after hysterectomy: a randomised controlled trial. (Abstract)

Effect of the EX-PLISSIT model on sexual function and sexual quality of life among women after hysterectomy: a randomised controlled trial. Background:After hysterectomy, most patients experience psychological problems and sexual dysfunction that can affect their sexual quality of life (QOL). This study determined the effects of counselling based on the Extended Permission-Limited Information-Specific Suggestion-Intensive Therapy (EX-PLISSIT) model on sexual function and sexual QOL after (...) hysterectomy among women attending hospitals in Sari, northern Iran. Methods: A randomised controlled trial was conducted between 2016 and 2017. Of 354 women undergoing hysterectomy, 80 women without anxiety, stress or depression who showed signs of sexual dysfunction were selected and, using blocked randomisation, were assigned to the intervention and control groups. The intervention group received two 1-h counselling sessions each week based on the EX-PLISSIT model. The control group received

2019 Sexual Health Controlled trial quality: uncertain

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