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Hypertrichosis

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41. Laser treatment for female facial hirsutism: are quality-of-life benefits sustainable? (Abstract)

Laser treatment for female facial hirsutism: are quality-of-life benefits sustainable? Facial hirsutism in women impairs quality of life (QoL). Laser hair removal (LHR) has been shown to confer significant improvements in QoL for up to 6 months after treatment, but the longer-term benefits have not been investigated.To assess the sustainability of LHR benefits to the QoL of hirsute women up to 30 months after treatment.Hirsute women about to undergo National Health Service (NHS)-funded LHR (...) in 2010-2012 (n = 142) completed proforma questionnaires quantifying the burden of hirsutism on their QoL. These included: the Dermatology Life Quality Index (DLQI) (assessing functional impact on QoL), the number of days spent removing hair per week and a 10-point scale assessing how much their condition bothered them (emotional burden on QoL). Postal questionnaires recorded QoL changes up to 30 months after LHR. Improvements in QoL scores for each woman were compared. Responses were then grouped

2015 Clinical & Experimental Dermatology

42. Adjuvant eflornithine to maintain IPL-induced hair reduction in women with facial hirsutism: a randomized controlled trial. (Abstract)

Adjuvant eflornithine to maintain IPL-induced hair reduction in women with facial hirsutism: a randomized controlled trial. Photoepilation is the treatment of choice for hair removal in patients with hirsutism, but it remains a challenge to prevent regrowth of hairs.The objective of this study was to investigate whether topical eflornithine maintains hair reduction in hirsute patients after cessation of intense pulsed light (IPL) therapy.A randomized, split-face, single-blinded controlled trial (...) on topical eflornithine vs. no eflornithine treatment (control) after 5-6 IPL-treatments in 22 women with facial hirsutism. Application of eflornithine was initiated after the final IPL-treatment (baseline) and applied twice daily for 6 months to half of the face. Patients were assessed at baseline and 1, 3 and 6 months after the final IPL-treatment. The primary endpoint was difference in facial hair counts between eflornithine vs. no treatment. Secondary endpoints were patient-evaluated efficacy

2015 Journal of the European Academy of Dermatology and Venereology : JEADV Controlled trial quality: uncertain

43. Complementary Therapies for Idiopathic Hirsutism: Topical Licorice as Promising Option. Full Text available with Trip Pro

Complementary Therapies for Idiopathic Hirsutism: Topical Licorice as Promising Option. Hirsutism is one of the most prevalent health problems in women. The aim of the study was to compare the effect of 755 nm alexandrite hair removal laser with that of alexandrite laser plus topical licorice on the improvement of idiopathic hirsutism. A double-blind, randomized placebo-controlled study was performed on 90 female subjects. The patients were divided into two groups: alexandrite laser plus 15 (...) % licorice gel (group A) and placebo (group B). Each subject received one of both products over one side of the face, twice daily for 24 weeks on the hirsute locations. Each group underwent five sessions of alexandrite laser at 6-week intervals. To minimize the effects of confounding variables, the test was performed on two separate zones of patients' skin. The mean ± SD numbers of terminal hairs in group A were 7.05 ± 4.55 for zone 1 and 6.06 ± 3.70 for zone 2. In group B, they were 3.18 ± 1.75 for zone

2015 Evidence-based Complementary and Alternative Medicine : eCAM Controlled trial quality: uncertain

44. A simplified questionnaire for self-assessment of hirsutism in population-based studies. Full Text available with Trip Pro

A simplified questionnaire for self-assessment of hirsutism in population-based studies. The measurement of excess body hair is not straightforward. As the modified Ferriman-Gallwey (mFG) score is unsuitable for self-assessment and requires specialist training, a short, self-administered questionnaire to identify hirsutism was constructed and validated for large-scale application, particularly targeting population-based studies.A validation study was conducted to assess a new hirsutism (...) similar answers regarding changes in the quantity of body hair over time, irrespective of how the questions were asked (P=0.000).The accuracy and internal consistency of this self-administered questionnaire for the identification of hirsutism were good. Therefore, this questionnaire represents a useful tool for self-assessment of hirsutism in population-based studies.© 2015 European Society of Endocrinology.

2015 European Journal of Endocrinology

45. Comparative Study of Diode Laser Versus Neodymium-Yttrium Aluminum: Garnet Laser Versus Intense Pulsed Light for the Treatment of Hirsutism Full Text available with Trip Pro

Comparative Study of Diode Laser Versus Neodymium-Yttrium Aluminum: Garnet Laser Versus Intense Pulsed Light for the Treatment of Hirsutism Lasers are widely used for the treatment of hirsutism. But the choice of the right laser for the right skin type is very important. Before starting with laser therapy, it is important to assess the skin type, the fluence, the pulse duration and the type of laser to be used.To compare the efficacy and side effects of Diode laser, Neodymium-yttrium aluminum (...) - garnet (Nd: YAG) laser and intense pulsed light (IPL) on 30 female patients of hirsutism.Thirty female patients with hirsutism were selected for a randomised controlled study. The patients were divided into three groups of 10 patients each. In group I patients diode laser was used, in group II patients long pulsed Nd: YAG laser was used and in group III, IPL was used. The patients were evaluated and result graded according to a 4-point scale as excellent, >75% reduction; good, 50-75% reduction; fair

2015 Journal of cutaneous and aesthetic surgery Controlled trial quality: uncertain

46. Hypertrichosis

at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN. Concepts Disease or Syndrome ( T047 ) MSH ICD10 , , SnomedCT 156409007 , 201164001 , 40090008 , 201165000 , 29966009 , 271607001 English Hypertrichoses , Hypertrichosis , HYPERTRICHOSIS , Hypertrichosis, unspecified , hypertrichosis (...) (diagnosis) , hypertrichosis , excess hair , Hypertrichosis [Disease/Finding] , excessive hairiness , polytrichia (diagnosis) , hypertrichosis polytrichia , polytrichia , Hypertrichosis NOS (disorder) , Pilosis , Excessive hair growth (disorder) , Polytrichia , Excessive hair growth , Hirsutism - hypertrichosis , Excessive hairiness , Excessive hair growth (finding) , Hypertrichiasis , Hypertrichosis (disorder) , Polytrichosis , Excessive growth of hair , Hairiness , excessive; hair growth

2018 FP Notebook

47. Treatment of Simple Hirsutism, Including the Hirsute Type of Stein—Leventhal Syndrome Full Text available with Trip Pro

Treatment of Simple Hirsutism, Including the Hirsute Type of Stein—Leventhal Syndrome 20788891 2011 04 04 2018 11 13 0007-1447 1 5182 1960 Apr 30 British medical journal Br Med J Treatment of Simple Hirsutism, Including the Hirsute Type of Stein-Leventhal Syndrome. 1298-300 Mattingly D D Mills I H IH Prunty F T FT eng Journal Article England Br Med J 0372673 0007-1447 2010 8 27 6 0 1960 4 30 0 0 1960 4 30 0 1 ppublish 20788891 PMC1967557 AMA Arch Intern Med. 1957 Nov;100(5):729-38 13468818 J

1960 British medical journal

48. Symposium on Adolescent Gynecology and Endocrinology. Part II: Secondary amenorrhea, hirsutism in adolescents and the clinical consequences of stilbestrol exposure in utero. Hirsutism in adolescents. Full Text available with Trip Pro

Symposium on Adolescent Gynecology and Endocrinology. Part II: Secondary amenorrhea, hirsutism in adolescents and the clinical consequences of stilbestrol exposure in utero. Hirsutism in adolescents. 545868 1980 07 12 2008 11 20 0093-0415 131 6 1979 Dec The Western journal of medicine West. J. Med. Symposium on Adolescent Gynecology and Endocrinology. Part II: Secondary amenorrhea, hirsutism in adolescents and the clinical consequences of stilbestrol exposure in utero. Hirsutism in adolescents (...) . 522-6 Braunstein G D GD eng Journal Article United States West J Med 0410504 0093-0415 0 Androgens IM Adolescent Androgens metabolism Female Hirsutism classification diagnosis etiology therapy Humans 1979 12 1 1979 12 1 0 1 1979 12 1 0 0 ppublish 545868 PMC1271912

1979 Western Journal of Medicine

49. Acne in hirsute women Full Text available with Trip Pro

Acne in hirsute women Acne and hirsutism are common manifestations of hyperandrogenism.To investigate whether or not acne is present in women with hirsutism, associated with different clinical, endocrine and ultrasonographic features.The prospective study included 135 women with hirsutism, aged 14-46 years. We measured the levels of hormones with radioimmunoassay/immunoradiometric assay methods.Acne were present in 63 (47.6%) women with hirsutism. Sixty women had mild forms of acne, including (...) : whiteheads, blackheads, papules and pustules. Only 3 women had moderate to severe acne, including nodules. In a group of women with hirsutism and acne, 6 (9.5%) were obese. In our study we found a high prevalence of androgen excess among hirsute women with acne: total testosterone was increased in 79%, free testosterone in 20.6%, androstenedione in 69.8%, dehydroepiandrosterone sulfate (DHEAS) in 30.1%, 17-OH-progesterone 68.2% and sex hormone-binding globulin (SHBG) was decreased in 33.3% of women

2014 Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii

50. Intermittent Low-Dose Finasteride Administration Is Effective for Treatment of Hirsutism in Adolescent Girls: A Pilot Study. (Abstract)

Intermittent Low-Dose Finasteride Administration Is Effective for Treatment of Hirsutism in Adolescent Girls: A Pilot Study. Hirsutism has negative impact on adolescent psychosocial development for both cosmetic and endocrine reasons. This study evaluated the effectiveness of a new intermittent, low-dose finasteride regimen consisting of 2.5 mg of drug given every 3 days (1 day of treatment, 2 days of drug withdrawal) for 6 months in girls with hirsutism by polycystic ovarian syndrome (PCOS (...) ) or idiopathic hirsutism (IH).Twenty-eight girls (15-19 y old) with hirsutism were randomly assigned to 2 treatment groups and treated for 6 months. Fourteen patients (7 with IH, 7 with PCOS) received finasteride; fourteen patients (7 with IH, 7 with PCOS) received placebo. Hirsutism score (HS), clinical, and hormonal effects were compared between the 2 groups.In patients treated with finasteride, the HS value at 6 months was 52.9% lower than that observed at baseline in girls with IH, and 52.8% lower

2014 Journal of pediatric and adolescent gynecology Controlled trial quality: uncertain

51. The effect of fennel (Foeniculum vulgare) gel 3% in decreasing hair thickness in idiopathic mild to moderate hirsutism, A randomized placebo controlled clinical trial. Full Text available with Trip Pro

The effect of fennel (Foeniculum vulgare) gel 3% in decreasing hair thickness in idiopathic mild to moderate hirsutism, A randomized placebo controlled clinical trial. Hirsutism is a common symptom presenting to primary care endocrinologists, gynecologists, and dermatologists. Management is usually a long and troublesome process. This study was designed to evaluate the effect of fennel topical gel on mild to moderate idiopathic hirsutism.The randomized, double-blind, placebo-controlled clinical (...) trial was carried out from 2009 to 2011, in Sari, Iran. Forty four women with mild to moderate idiopathic hirsutism were randomly divided to case and control groups, each group included 22 cases. The case group received fennel gel 3% and the control group received placebo. The effect of fennel gel 3% was defined as reduction of thickness of facial hair in micrometer by microscope in comparison with placebo. Measurements were performed at zero time and 24 weeks after treatment. This study

2014 Caspian journal of internal medicine Controlled trial quality: uncertain

52. Evaluation of insulin resistance in idiopathic hirsutism compared with polycystic ovary syndrome patients and healthy individuals. (Abstract)

Evaluation of insulin resistance in idiopathic hirsutism compared with polycystic ovary syndrome patients and healthy individuals. Hirsutism is defined as the excessive male-pattern growth of hair in women. Hirsutism is often idiopathic or the consequence of polycystic ovary syndrome (PCOS). Insulin resistance is common in PCOS (especially in obese patients) but the association between insulin resistance and idiopathic hirsutism (IH) is not clear. The aim of this study was to investigate (...) the rate of insulin resistance in IH, compared with healthy individuals and patients with PCOS.The study included three groups, patients with idiopathic hirsutism, PCOS and healthy women. Each group included 30 non-obese women. Fasting blood sugar (FBS), insulin level and insulin resistance (estimated by the homeostasis model assessment [HOMA-IRIR]) were compared in the three groups.There was a significant difference between the age of the women with IH compared with two other groups. There were

2014 Australasian Journal of Dermatology

53. Role of the combination spironolactone-norgestimate-estrogen in Hirsute women with polycystic ovary syndrome. (Abstract)

Role of the combination spironolactone-norgestimate-estrogen in Hirsute women with polycystic ovary syndrome. To compare the combination spironolactone-norgestimate-ethinyl estradiol in hirsutism with other protocols including the same dose of estrogen.In this open prospective study, 167 women with hirsutism due to polycystic ovary syndrome (PCOS) were randomly assigned to the following treatment protocols: Group A (n = 72): spironolactone 100 mg-norgestimate 250 mcg-ethinyl estradiol 35 microg (...) ; Group B (n = 70): cyproterone acetate 12 mg-ethinyl estradiol 35 microg; Group C (n = 25): norgestimate 250 microg-ethinyl estradiol 35 microg.The decrease in the hirsutism score was higher in group A than in the other groups (p < 0.001) and comparable in groups B and C. The decrease in acne score, androgen and estradiol levels, and ovary volume was similar in groups A and B. C-reactive protein increase was similar in all groups, but the augmentation of fibrinogen (p = 0.04), triglycerides (p < 0.01

2014 Journal of Reproductive Medicine Controlled trial quality: uncertain

54. The comparison of various adiposity indexes in women with polycystic ovary syndrome and normo-ovulatory non hirsute women; a population based study. Full Text available with Trip Pro

The comparison of various adiposity indexes in women with polycystic ovary syndrome and normo-ovulatory non hirsute women; a population based study. Insulin resistance (IR) and metabolic disorders are common in polycystic ovary syndrome (PCOS). However, it is still not clear which adiposity marker could precisely predict metabolic syndrome (MetS) in women with PCOS and whether these indexes are different in normo-ovulatory non-hirsute women.A case-control study was conducted on a total of 175

2014 European Journal of Endocrinology

55. Flutamide: Hirsutism in Women Full Text available with Trip Pro

Flutamide: Hirsutism in Women This Hospital Pharmacy feature is extracted from Off-Label Drug Facts, a publication available from Wolters Kluwer Health. Off-Label Drug Facts is a practitioner-oriented resource for information about specific drug uses that are unapproved by the US Food and Drug Administration. This new guide to the literature enables the health care professional or clinician to quickly identify published studies on off-label uses and determine if a specific use is rational

2014 Hospital pharmacy

56. Hirsutism (Diagnosis)

, and areolae. Idiopathic hirsutism in an elderly woman. Although the terms hirsutism and hypertrichosis often are used interchangeably, hypertrichosis actually refers to excess hair (terminal or vellus) in areas that are not predominantly androgen dependent. Whether a patient is hirsute often is difficult to judge because hair growth varies among individual women and across ethnic groups. What is considered hirsutism in one culture may be considered typical in another. For example, women from (...) of action of these drugs on hair follicles is not known, but the same mechanisms do not appear to be involved in all patients. Drug-induced hirsutism can be distinguished from drug-induced hypertrichosis, in which a uniform growth of fine hair appears over extensive areas of the trunk, hands, and face and is unrelated to androgen-dependent hair growth. Adrenal causes of hirsutism CAH in children (ie, the classic form of adrenal hyperplasia) may cause hirsutism. These children may be born with ambiguous

2014 eMedicine.com

57. Hirsutism (Diagnosis)

Hirsutism (Diagnosis) Hirsutism: Practice Essentials, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIxMDM4LW92ZXJ2aWV3 processing > Hirsutism Updated: Apr 13, 2018 Author: George T (...) Griffing, MD; Chief Editor: Michel E Rivlin, MD Share Email Print Feedback Close Sections Sections Hirsutism Overview Practice Essentials Although hirsutism is broadly defined as excessive hairiness, the common clinical use of the term refers to women with excess growth of terminal hair in a male pattern. In this sense, hirsutism is one of the most common endocrine disorders, affecting approximately 10% of women in the United States. In these women, the hairiness implies the presence of abnormal

2014 eMedicine.com

58. Hirsutism (Treatment)

be combined with laser treatments for enhanced effects. [ ] Metformin (Glucophage) reduces insulin levels, and this change, in turn, reduces the ovarian testosterone levels by competitive inhibition of the ovarian insulin receptors. This drug is effective in treating hirsutism in women with PCOS. Management depends on the underlying cause. For example, non–androgen-dependent excess hair, such as hypertrichosis, is treated primarily with physical hair removal methods. In contrast, patients with androgen (...) Hirsutism (Treatment) Dermatologic Manifestations of Hirsutism Treatment & Management: Medical Care, Surgical Care, Diet Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA3MjAzMS10cmVhdG1lbnQ= processing

2014 eMedicine.com

59. Hirsutism (Treatment)

Hirsutism (Treatment) Hirsutism Treatment & Management: Medical Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTIxMDM4LXRyZWF0bWVudA== processing > Hirsutism Treatment & Management Updated: Apr 13, 2018 (...) Author: George T Griffing, MD; Chief Editor: Michel E Rivlin, MD Share Email Print Feedback Close Sections Sections Hirsutism Treatment Medical Care The treatment of hirsutism begins with a careful explanation about the cause of the problem and reassurance that the patient is not losing her femininity. Then, direct intervention, if possible, is instituted for the underlying disorder. If hirsutism persists (or the patient has idiopathic hirsutism), other cosmetic or systemic treatment may be necessary

2014 eMedicine.com

60. Hirsutism (Overview)

. Idiopathic hirsutism in an elderly woman. Although the terms hirsutism and hypertrichosis often are used interchangeably, hypertrichosis actually refers to excess hair (terminal or vellus) in areas that are not predominantly androgen dependent. Whether a patient is hirsute often is difficult to judge because hair growth varies among individual women and across ethnic groups. What is considered hirsutism in one culture may be considered typical in another. For example, women from the Mediterranean (...) , but the same mechanisms do not appear to be involved in all patients. Drug-induced hirsutism can be distinguished from drug-induced hypertrichosis, in which a uniform growth of fine hair appears over extensive areas of the trunk, hands, and face and is unrelated to androgen-dependent hair growth. Adrenal causes of hirsutism CAH in children (ie, the classic form of adrenal hyperplasia) may cause hirsutism. These children may be born with ambiguous genitalia, symptoms of salt wasting, and failure to thrive

2014 eMedicine.com

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