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Hypertension Evaluation History

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161. Pulmonary vein isolation combined with spironolactone or renal sympathetic denervation in patients with chronic kidney disease, uncontrolled hypertension, paroxysmal atrial fibrillation, and a pacemaker. (PubMed)

could reduce the recurrence of AF in patients with CKD by modulating sympathetic hyperactivity. We aimed to evaluate the impact of RSD or spironolactone 50 mg/day associated with PVI in reducing systolic blood pressure (BP), AF recurrence, and AF burden in patients with a history of paroxysmal AF and mild CKD.This was a single-center, prospective, longitudinal, randomized, double-blind study. The individuals were randomly divided into two groups (PVI + spironolactone, n = 36, and PVI + RSD, n = 33 (...) Pulmonary vein isolation combined with spironolactone or renal sympathetic denervation in patients with chronic kidney disease, uncontrolled hypertension, paroxysmal atrial fibrillation, and a pacemaker. Atrial fibrillation (AF) commonly occurs in chronic kidney disease (CKD), occasioning adverse outcomes. Merging pulmonary vein isolation (PVI) and renal sympathetic denervation (RSD) may decrease the recurrence of AF in subjects with CKD and uncontrolled hypertension. We considered that RSD

2018 Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

162. MKSAP: 53-year-old woman with hypertension and chronic active hepatitis B infection

MKSAP: 53-year-old woman with hypertension and chronic active hepatitis B infection Kidney disease with a tubulointerstitial process MKSAP: 53-year-old woman with hypertension and chronic active hepatitis B infection | | December 8, 2018 0 Shares Test your medicine knowledge with the , in partnership with the . A 53-year-old woman is evaluated during a routine follow-up visit. Medical history is significant for hypertension and chronic active hepatitis B infection. Her hepatitis B infection has (...) : Bicarbonate 21 mEq/L (21 mmol/L) Creatinine 1.2 mg/dL (106.1 µmol/L) (3 years ago: 0.8 mg/dL [70.7 µmol/L]) Glucose 87 mg/dL (4.8 mmol/L) Phosphorus 2.2 mg/dL (0.71 mmol/L) Urinalysis 1+ protein; 2+ glucose; no cells or casts Which of the following is the most likely cause of this patient’s kidney findings? A. Hypertensive nephropathy B. Membranoproliferative glomerulonephritis C. Membranous glomerulopathy D. Tubulointerstitial disease MKSAP Answer and Critique The correct answer is D. Tubulointerstitial

2018 KevinMD blog

163. Abstract 79: Chronic and Acute Hypertension in Ischemic Stroke Are Distinct Markers of Impaired Collateral Circulation. (PubMed)

in those with both history of HTN and acutely elevated BP.Chronic and acute HTN are both potent predictors of impaired collaterals in AIS. Understanding how HTN affects the structure and function of collaterals and response to acute BP changes is critical for future hypertensive management and collateral augmentation. (...) Abstract 79: Chronic and Acute Hypertension in Ischemic Stroke Are Distinct Markers of Impaired Collateral Circulation. Acute blood pressure (BP) elevation in acute ischemic stroke (AIS) is common, yet the link with collateral circulation remains elusive due to lack of longitudinal data on premorbid hypertension (HTN) and serial BP changes within an individual. Precision medicine for AIS and management of HTN requires an understanding of collateral circulation.The Interventional Management

2018 Stroke

164. Antihypertensive Medication and Dementia Risk in Older Adult African Americans with Hypertension: A Prospective Cohort Study. (Full text)

-dwelling patients from an inner-city public health care system, aged 65 years and older, with a history of hypertension but no history of dementia, and who had at least three primary care visits and a prescription filled for any medication.Blood pressure was the average of three seated measurements. Dementia was diagnosed using a two-stage design, with a screening evaluation every 2 to 3 years followed by a comprehensive in-home clinical evaluation for those with a positive screen. Laboratory (...) Antihypertensive Medication and Dementia Risk in Older Adult African Americans with Hypertension: A Prospective Cohort Study. African Americans are especially at risk of hypertension and dementia. Antihypertensive medications reduce the risk of cardiovascular events, but may also reduce the risk of dementia.To assess the longitudinal effects of antihypertensive medications and blood pressure on the onset of incident dementia in a cohort of African Americans.Prospective cohort.1236 community

2018 Journal of General Internal Medicine PubMed

165. Nasal / Wrist Acupuncture Laser Radiation for Hypertensive and High Blood Viscosity Patients

Information provided by (Responsible Party): Ebtesam Nabil, Cairo University Study Details Study Description Go to Brief Summary: This study will evaluate the effect of low level laser blood radiation applied to all participants for prevention of coronary artery disease in patients with high risk (hypertension,high blood viscosity, hypercholesterolemia as well as related immune issues) Condition or disease Intervention/treatment Phase Cardiovascular Risk Factor Coronary Artery Disease Device: low level (...) research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 55 Years to 65 Years (Adult, Older Adult) Sexes Eligible for Study: Female Accepts Healthy Volunteers: No Criteria Inclusion Criteria: stage I hypertensive patients patients from 30 to 34.9 kg/m2 body mass index medically stable patients all participants have sufficient cognition enough to understand the requirements of the study Exclusion Criteria: history

2018 Clinical Trials

166. Treatment of Hypertension During Sleep

thresholds for hypertension and therapeutic targets for treatment of all individuals aged ≥18 years regardless of age, sex, or concomitant complications including presence of diabetes, chronic kidney disease (CKD), or history of past CVD event. According to these guidelines, the new proposed ambulatory BP measurment (ABPM) thresholds for diagnosis of hypertension in adults are 130/80 and 110/65 mmHg for the awake and asleep SBP/DBP means, respectively. However, the ACC/AHA guidelines do not provide any (...) randomized study has ever before evaluated which should be the adequate therapeutic ABPM target for most effective reduction of CVD risk. Accordingly, the Tratamiento de Hipertensión Arterial Durante el Sueño study (THADEUS, i.e., Treatment of Hypertension During Sleep) has been designed to prospectively evaluate if "intensive control" of asleep SBP mean proposed by the new ACC/AHA guidelines (<110 mmHg) in more effective than the so far its "conventional control" (<120 mmHg) to reduce CVD morbidity

2018 Clinical Trials

167. Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients With Mild to Moderate Hypertension

the maximum number of saved studies (100). Please remove one or more studies before adding more. Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients With Mild to Moderate Hypertension The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03462069 Recruitment Status : Active (...) converting enzyme (ACE) inhibitor or Angiotensin Receptor Blocker (ARB) under standardized diet conditions. Secondary Objectives: To compare the renal and cardiovascular PD effects of an 8 weeks treatment with sotagliflozin QD to an 8 weeks treatment to empagliflozin QD in mild or moderate hypertensive T2DM patients on a stable treatment regimen with metformin and an ACE inhibitor or ARB. To evaluate the safety and tolerability of an 8 weeks QD treatment with sotagliflozin or empagliflozin in mild

2018 Clinical Trials

168. The FVC/DLCO Ratio is a Useful Predictor of Pulmonary Hypertension in Patients With Interstitial Lung Disease

(100). Please remove one or more studies before adding more. The FVC/DLCO Ratio is a Useful Predictor of Pulmonary Hypertension in Patients With Interstitial Lung Disease The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03396120 Recruitment Status : Completed First Posted : January 10, 2018 Last (...) and clinical outcomes. Objectives: To evaluate the usefulness of assessing forced vital capacity (FVC%), diffusion capacity of the lung for carbon monoxide (DLCO%), and FVC%/DLCO% ratio to predict pulmonary hypertension among patients with ILDs. Condition or disease Intervention/treatment Interstitial Lung Disease Pulmonary Hypertension Diagnostic Test: Pulmonary function test Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 95 participants Observational

2018 Clinical Trials

169. A Clinical Study in France to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Arterial Hypertension Who Were Previously Treated With Macitentan in Clinical Studies.

A Clinical Study in France to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Arterial Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. A Clinical Study in France to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Arterial Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer (...) to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Clinical Study in France to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Arterial Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. The safety and scientific validity of this study

2018 Clinical Trials

170. Potato Consumption and Risk of Hypertension

time Adults with no chronic disease history Exclusion Criteria: Adults aged < 20 years Identified to be pregnant Previously diagnosed with hypertension, cancers, infarction, apoplexy, and diabetes Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number (...) Potato Consumption and Risk of Hypertension Potato Consumption and Risk of Hypertension - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Potato Consumption and Risk of Hypertension The safety and scientific

2018 Clinical Trials

171. Clinical Characteristics of Parkinson's Disease Subjects With Severe Hypertension During Motor OFFs.

remove one or more studies before adding more. Clinical Characteristics of Parkinson's Disease Subjects With Severe Hypertension During Motor OFFs. (CLIN-HTN-PD) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03433950 (...) Clinical Characteristics of Parkinson's Disease Subjects With Severe Hypertension During Motor OFFs. Clinical Characteristics of Parkinson's Disease Subjects With Severe Hypertension During Motor OFFs. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please

2018 Clinical Trials

172. Effects of Preoperative Operating Room Environment Presentation in Hypertensive Patients

before adding more. Effects of Preoperative Operating Room Environment Presentation in Hypertensive Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03711201 Recruitment Status : Completed First Posted : October 18, 2018 Last Update Posted : December 4, 2018 Sponsor: Yuzuncu Yıl University (...) information, Layout table for eligibility information Ages Eligible for Study: 40 Years to 80 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: elective surgery informed consent, essential hypertension was diagnosed, Between the ages of 40-80, American Society of Anesthesiologists (ASA) class II-III Exclusion Criteria: drug allergy, with a history of malignant hyperthermia, uncontrolled hypertension, cancer and psychological problems

2018 Clinical Trials

173. The Use of TRIple Fixed-dose COmbination in the Treatment of arteriaL Hypertension: Opportunity for Effective BP Control With cOmbined Antihypertensive theRapy

Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Use of TRIple Fixed-dose COmbination in the Treatment of arteriaL Hypertension: Opportunity for Effective BP Control With cOmbined Antihypertensive theRapy (TRICOLOR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated (...) , or secondary arterial hypertension Office BP ≥ 180/110 mm Hg on treatment (at V0 visit) History of myocardial infarction, unstable angina, or cerebrovascular accident within the past 1 year CHF of class III-IV NYHA Type I diabetes or decompensated type 2 diabetes Diseases with severe organ dysfunction (hepatic failure, renal failure, etc.) Contraindications to or known intolerance of dihydropyridine calcium channel blockers (including amlodipine) and/or indapamide and/or ACE inhibitors (including

2018 Clinical Trials

174. A Randomized Trial Comparing Oral Misoprostol Alone With Oral Misoprostol Followed by Oxytocin in Women Induced for Hypertension of Pregnancy

this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Randomized Trial Comparing Oral Misoprostol Alone With Oral Misoprostol Followed by Oxytocin in Women Induced for Hypertension of Pregnancy (MOLI) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk (...) A Randomized Trial Comparing Oral Misoprostol Alone With Oral Misoprostol Followed by Oxytocin in Women Induced for Hypertension of Pregnancy A Randomized Trial Comparing Oral Misoprostol Alone With Oral Misoprostol Followed by Oxytocin in Women Induced for Hypertension of Pregnancy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save

2018 Clinical Trials

175. Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine

Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine (PRECIOUS) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government (...) Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved

2018 Clinical Trials

176. A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension

. A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (SPECTRA) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03738150 Recruitment Status : Recruiting First Posted : November 12, 2018 Last Update (...) Posted : March 21, 2019 See Sponsor: Acceleron Pharma, Inc. Information provided by (Responsible Party): Acceleron Pharma, Inc. Study Details Study Description Go to Brief Summary: This study evaluates the effect of sotatercept (ACE-011) in adults with Pulmonary Arterial Hypertension. Each eligible participant will receive standard of care (SOC) plus sotatercept (ACE-011) for a 24 week treatment period followed by a 16 week follow up period. Condition or disease Intervention/treatment Phase Pulmonary

2018 Clinical Trials

177. Recurrence of pre-eclampsia and the risk of future hypertension and cardiovascular disease: a systematic review and meta-analysis. (PubMed)

Recurrence of pre-eclampsia and the risk of future hypertension and cardiovascular disease: a systematic review and meta-analysis. Women with a history of hypertensive disorders, including pre-eclampsia, during pregnancy have a two- to-five-fold increased risk of cardiovascular disease (CVD). In 15% of women, pre-eclampsia recurs in the following pregnancy.To evaluate all evidence on the future risk of developing hypertension and CVD after multiple pregnancies complicated by pre-eclampsia (...) compared with pre-eclampsia in a single pregnancy followed by normal subsequent pregnancy.Embase and Medline were searched until June 2017.All relevant studies on the risk of developing hypertension, atherosclerosis, ischaemic heart disease, cerebrovascular accident (CVA), thromboembolism, heart failure or overall hospitalisation and mortality due to CVD after having had recurrent pre-eclampsia.Twenty-two studies were included in the review. When possible, we calculated pooled risk ratios (RR) with 95

2018 BJOG

178. Gender differences of aortic wave reflection and influence of menopause on central blood pressure in patients with arterial hypertension. (Full text)

and postmenopausal status on aortic waveform reflection is scarce. We aim to evaluate the impact of gender and menopause on central blood pressure of hypertensive patients.In a cross sectional study 122 hypertensive patients (52 men and 70 women) were studied. Hypertension was defined as blood pressure (BP) levels ≥140/90 mmHg or use of antihypertensive drugs. Central arterial pressure, augmentation index (AIx) and augmentation index normalized to 75 bpm (AIx75) were obtained using applanation tonometry (...) Gender differences of aortic wave reflection and influence of menopause on central blood pressure in patients with arterial hypertension. Evidences suggest that central hemodynamics indexes are independent predictors of future cardiovascular events and all-cause mortality. Multiple factors have been pointed to have potential influence on central aortic function: height, heart rate, left ventricular ejection duration and blood pressure level. Data related to the influence of gender

2018 BMC Cardiovascular Disorders PubMed

179. MKSAP: 47-year-old man with hypertension, type 2 diabetes mellitus, and obstructive sleep apnea

MKSAP: 47-year-old man with hypertension, type 2 diabetes mellitus, and obstructive sleep apnea Referral for bariatric surgery should be considered in all patients with a BMI of 40 or higher MKSAP: 47-year-old man with hypertension, type 2 diabetes mellitus, and obstructive sleep apnea | | May 26, 2018 2 Shares Test your medicine knowledge with the , in partnership with the . A 47-year-old man is evaluated during a follow-up examination. He is obese and has hypertension, type 2 diabetes (...) mellitus, and obstructive sleep apnea. He reports that he has always has been overweight, and over the years, his weight has gradually increased to 123 kg (271 lb). During the past 2 years, he has tried several commercial diets; a dietician-monitored, calorie-restricted diet; increased physical activity; orlistat; and a combination of these interventions, all without achieving sustained weight loss. Medical history is also significant for bilateral knee pain and depression. He uses continuous positive

2018 KevinMD blog

180. Pulmonary hypertension due to unclassified interstitial lung disease in a Pembroke Welsh corgi (Full text)

Pulmonary hypertension due to unclassified interstitial lung disease in a Pembroke Welsh corgi A 12 year-old intact male Pembroke Welsh corgi weighing 10.8 kg was presented for evaluation of a 3-month history of dyspnea, and a 1-week history of exercise intolerance and anorexia. Severe hypoxemia (PaO2 56 mmHg), diffuse lung alveolar infiltration, and severe pulmonary hypertension (PH) (tricuspid regurgitation pressure gradient was 81 mmHg) were identified. A tentative diagnosis of severe PH due

2018 The Journal of Veterinary Medical Science PubMed

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