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Hypertension Evaluation History

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141. Esophageal Capsule Endoscopy (ECE) in Children and Young Adults with Portal Hypertension. (Abstract)

Esophageal Capsule Endoscopy (ECE) in Children and Young Adults with Portal Hypertension. Variceal hemorrhage (VH) is a serious complication of portal hypertension (PH). We evaluated the feasibility, safety, and clinical impact of esophageal capsule endoscopy (ECE) in pediatric and young adult patients with known or suspected portal hypertension.Children and young adults with PH at Boston Children's Hospital (2005-2017) were offered ECE for variceal screening or surveillance. Patient histories (...) , ECE findings, and clinical outcomes were reviewed retrospectively.149 ECE studies were performed in 98 patients (57.1% male) using 3 ECE devices for variceal screening (66.5%) or surveillance (33.5%). 3 readers interpreted the studies (88.3%, 10.3%, and 1.4%, respectively). Median age was 16y (IQR 13.7, 18.5). 103 ECE studies involved patients <18y (69.1%). 15 patients (29 ECE studies) had a GI bleeding (GIB) history, 5 in the preceding 12m.62 ECE studies (44.9%) detected varices: 59 esophageal

2019 Journal of Pediatric Gastroenterology and Nutrition

142. The effects of self-management education tailored to health literacy on medication adherence and blood pressure control among elderly people with primary hypertension: A randomized controlled trial. (Abstract)

The effects of self-management education tailored to health literacy on medication adherence and blood pressure control among elderly people with primary hypertension: A randomized controlled trial. To evaluate the effects of self-management education tailored to health literacy on medication adherence and blood pressure control.This randomized controlled trial was conducted in 2018 with 118 elderly people with uncontrolled primary hypertension and inadequate health literacy. Self-management (...) education was developed on the basis of the health literacy index. Medication adherence and blood pressure were assessed using 8-items Morisky Medication Adherence Scale and a mercury sphygmomanometer, respectively.At baseline, there were no significant between-group differences regarding participants' demographic characteristics, medical history, and medication adherence. After the intervention, between-group comparisons adjusted for pretest scores showed a significant reduction in the mean score

2019 Patient education and counseling Controlled trial quality: uncertain

143. Patient-Level Prediction of Cardio-Cerebrovascular Events in Hypertension Using Nationwide Claims Data. Full Text available with Trip Pro

management via the nationwide health maintenance program, and health care providers should inform patients about their risks of a complication caused by hypertension.Our goal was to develop and compare machine learning models predicting high-risk vascular diseases for hypertensive patients so that they can manage their blood pressure based on their risk level.We used a 12-year longitudinal dataset of the nationwide sample cohort, which contains the data of 514,866 patients and allows tracking of patients (...) test F1-score=.705). Concerning the number of features, in the within test, the long short-term memory-based algorithms outperformed regardless of the number of features. However, in the external test, the random forest-based algorithm was the best, irrespective of the number of features it encountered.We developed and compared machine learning models predicting high-risk vascular diseases in hypertensive patients so that they may manage their blood pressure based on their risk level. By relying

2019 Journal of medical Internet research

144. Interaction between low-density lipoprotein-cholesterolaemia, serum uric level and incident hypertension: data from the Brisighella Heart Study. (Abstract)

selected from the general database of the Brisighella Heart Study four groups of age and sex-matched nonhypertensive individuals with different levels of LDL-C and SUA level and examined during the 2008 population survey. Incident hypertension has been defined as the increase of SBP values over 140 mmHg and/or of DBP over 90 mmHg and or the beginning of an antihypertensive treatment.In a model adjusted for age, sex, baseline blood pressure, family history of hypertension, smoking status, BMI (...) Interaction between low-density lipoprotein-cholesterolaemia, serum uric level and incident hypertension: data from the Brisighella Heart Study. Previous evidence suggest that high low-density lipoprotein cholesterol (LDL-C) and serum uric acid (SUA) levels are risk factors for endothelial dysfunction and vascular ageing. The aim of our study was to evaluate the short-term interaction between SUA, LDL-C and incident hypertension in a sample of overall healthy individuals.In January 2018, we

2019 Journal of Hypertension

145. Management of Arterial Hypertension

antihypertensive drug treatment . . . . .2178 4.2.1 Recommendations of previous Guidelines . . . . . . .2178 4.2.2 Grade 2 and 3 hypertension and high-risk grade 1 hypertension . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2179 4.2.3 Low-to-moderate risk, grade 1 hypertension . . . . . .2179 4.2.4 Isolated systolic hypertension in youth . . . . . . . . . .2181 4.2.5 Grade 1 hypertension in the elderly . . . . . . . . . . .2181 4.2.6 High normal blood pressure . . . . . . . . . . . . . . . .2181 (...) 4.2.7 Summary of recommendations on initiation of antihypertensive drug treatment . . . . . . . . . . . . . . . .2181 4.3 Blood pressure treatment targets . . . . . . . . . . . . . . . .2182 4.3.1 Recommendations of previous Guidelines . . . . . . .2182 4.3.2 Low-to-moderate risk hypertensive patients . . . . . .2182 4.3.3 Hypertension in the elderly . . . . . . . . . . . . . . . . .2182 4.3.4 High-risk patients . . . . . . . . . . . . . . . . . . . . . . .2182 ESH and ESC Guidelines 2160 Downloaded

2013 European Society of Cardiology

146. Healthful Dietary Patterns and the Risk of Hypertension Among Women With a History of Gestational Diabetes Mellitus: A Prospective Cohort Study. Full Text available with Trip Pro

Healthful Dietary Patterns and the Risk of Hypertension Among Women With a History of Gestational Diabetes Mellitus: A Prospective Cohort Study. Women who developed gestational diabetes mellitus represent a high-risk population for hypertension later in life. The role of diet in the progression of hypertension among this susceptible population is unknown. We conducted a prospective cohort study of 3818 women with a history of gestational diabetes mellitus in the Nurses' Health Study II as part (...) of the ongoing Diabetes & Women's Health Study. These women were followed-up from 1989 to 2011. Incident hypertension was identified through self-administered questionnaires that were validated previously by medical record review. Adherence scores for the alternative Healthy Eating Index 2010, the alternative Mediterranean diet, and the Dietary Approaches to Stop Hypertension were computed for each participant. Cox proportional hazard models were used to evaluate the associations between dietary scores

2016 Hypertension

147. MKSAP: 54-year-old man with elevated blood pressure

MKSAP: 54-year-old man with elevated blood pressure Ambulatory blood pressure monitoring may be helpful in diagnosing masked hypertension MKSAP: 54-year-old man with elevated blood pressure | | September 16, 2017 25 Shares Test your medicine knowledge with the , in partnership with the . A 54-year-old man is evaluated for elevated blood pressure noted recently at a local health fair. He has no other medical history and takes no medications. On this visit and on two subsequent nurse visits (...) . A plasma renin-plasma aldosterone ratio is used to evaluate for hyperaldosteronism as a secondary cause of hypertension and is typically indicated in patients with difficult-to-treat blood pressure elevations and hypokalemia. This patient has not been diagnosed with hypertension and has no electrolyte abnormalities. Because this patient has evidence of end-organ damage possibly due to hypertension, follow-up assessment of his blood pressures in 6 months might further delay diagnosis

2017 KevinMD blog

148. Evaluation of Allergy to Tacrolimus in Kidney Transplant Candidates and Recipients with a History of Macrolide Antibiotic Allergy. Full Text available with Trip Pro

Evaluation of Allergy to Tacrolimus in Kidney Transplant Candidates and Recipients with a History of Macrolide Antibiotic Allergy. 29673079 2018 07 06 1600-6143 18 7 2018 Jul American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Am. J. Transplant. Evaluation of allergy to tacrolimus in kidney transplant candidates and recipients with a history of macrolide antibiotic allergy. 1831-1832 10.1111/ajt.14879 (...) Trofe-Clark J J Department of Pharmacy Services, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. Renal, Electrolyte, Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Doshi M M Temple University School of Pharmacy, Philadelphia, PA, USA. Fadugba O O Pulmonary Allergy Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Lim M A MA Renal, Electrolyte, Hypertension Division

2018 American Journal of Transplantation

149. Association Between Family History and Hypertension Among Chinese Elderly. Full Text available with Trip Pro

relatives with hypertension (FH1), and 2 generations of first-degree relatives with hypertension (FH2). The prevalence of hypertension was 53.0%. Participants with positive family history had a significantly higher prevalence of hypertension (67.5%, 95% CI: 63.3-71.7) than those without (47.9%, 95% CI: 45.2-50.6), and even among participants without hypertension, the blood pressure levels were higher with positive FH. Multiple logistic regression analysis showed that a significantly linear-trend (...) increase in hypertension according to family history of first degree relative numbers was observed in both genders (P for trend < 0.001). This study suggests that family history had not only a significant but also graded association with hypertension and with blood pressure levels, and this association exists even among those without hypertension.

2015 Medicine

150. Natural History of Noncirrhotic Portal Hypertension

Diseases (NIDDK) Information provided by (Responsible Party): National Institutes of Health Clinical Center (CC) ( National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ) Study Details Study Description Go to Brief Summary: Background: - Noncirrhotic Portal Hypertension (NCPH) is caused by liver diseases that increase pressure in the blood vessels of the liver. It seems to start slowly and not have many warning signs. Many people may not even know that they have a liver disease (...) . Sound waves measure liver stiffness. - Visit 2: Blood tests Abdominal MRI Echocardiogram Questionnaire Liver blood vessel pressure (hepatic venous portal gradient (HVPG)) measurement. This is done with a small tube inserted in a neck vein. They may have a liver biopsy. All participants will visit the clinic every 6 months for a history, physical exam, and blood tests. They will also repeat some of the screening tests yearly. Participants with NCPH will also have: Upper endoscopy test. A tube

2015 Clinical Trials

151. The influence of family history of Hypertension on disease prevalence and associated metabolic risk factors among Sri Lankan adults. Full Text available with Trip Pro

representative sample from Sri Lanka.A cross-sectional survey among 5,000 Sri Lankan adults, evaluating FH at the levels of parents, grandparents, siblings and children. A binary logistic regression analysis was performed in all patients with 'presence of hypertension' as dichotomous dependent variable and using family history in parents, grandparents, siblings and children as binary independent variables. The adjusted odds ratio controlling for confounders (age, gender, body mass index, diabetes (...) The influence of family history of Hypertension on disease prevalence and associated metabolic risk factors among Sri Lankan adults. Hypertension is a major contributor to the global non-communicable disease burden. Family history is an important non-modifiable risk factor for hypertension. The present study aims to describe the influence of family history (FH) on hypertension prevalence and associated metabolic risk factors in a large cohort of South Asian adults, from a nationally

2015 BMC Public Health

152. A Prospective Study of B244 Delivered as a Topical Spray to Determine Safety and Efficacy in Subjects With Elevated Blood Pressure

reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Prospective Study of B244 Delivered as a Topical Spray to Determine Safety and Efficacy in Subjects With Elevated Blood Pressure The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02998840 (...) the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Male and female subjects ≥18 years of age In good general health as determined by a thorough medical history and physical examination, and vital signs Clinical diagnosis of elevated Blood Pressure defined as: Having systolic prehypertension measurements having

2016 Clinical Trials

153. Pulmonary vein isolation combined with spironolactone or renal sympathetic denervation in patients with chronic kidney disease, uncontrolled hypertension, paroxysmal atrial fibrillation, and a pacemaker. (Abstract)

could reduce the recurrence of AF in patients with CKD by modulating sympathetic hyperactivity. We aimed to evaluate the impact of RSD or spironolactone 50 mg/day associated with PVI in reducing systolic blood pressure (BP), AF recurrence, and AF burden in patients with a history of paroxysmal AF and mild CKD.This was a single-center, prospective, longitudinal, randomized, double-blind study. The individuals were randomly divided into two groups (PVI + spironolactone, n = 36, and PVI + RSD, n = 33 (...) Pulmonary vein isolation combined with spironolactone or renal sympathetic denervation in patients with chronic kidney disease, uncontrolled hypertension, paroxysmal atrial fibrillation, and a pacemaker. Atrial fibrillation (AF) commonly occurs in chronic kidney disease (CKD), occasioning adverse outcomes. Merging pulmonary vein isolation (PVI) and renal sympathetic denervation (RSD) may decrease the recurrence of AF in subjects with CKD and uncontrolled hypertension. We considered that RSD

2018 Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing Controlled trial quality: uncertain

154. Decreases in adiposity reduce the risk of hypertension: Results from a prospective cohort of adolescents. (Abstract)

Decreases in adiposity reduce the risk of hypertension: Results from a prospective cohort of adolescents. This study aimed to evaluate the effect of age-related changes in body mass index and waist circumference during adolescence on blood pressure levels and incidence of hypertension. Among the 2159 adolescents recruited at 13 years in Porto, Portugal, we evaluated those free of hypertension at baseline and followed-up at 17 years (n = 1377) - EPITeen cohort, 2003-2008. Changes in BMI (...) percentage (BMI%) and waist circumference percentage (WC%) were evaluated continuously as the difference between 13 and 17 years, then categorized in sex-specific quartiles. Hypertension was defined as systolic and/or diastolic blood pressure ≥ 95th sex- age- and height-specific reference percentile. The association between changes in adiposity and incidence of hypertension was computed through generalized linear models with log link function and Poisson distribution [incidence rate ratios (IRR), 95

2018 Preventive Medicine

155. Chronic Thromboembolic Pulmonary Hypertension: An Update. Full Text available with Trip Pro

Chronic Thromboembolic Pulmonary Hypertension: An Update. Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive pulmonary vascular disease with significant morbidity. It is a result of an alternate natural history in which there is limited resolution of thromboemboli with pulmonary artery obstruction leading to pulmonary hypertension (PH). CTEPH requires a thorough clinical assessment including pulmonary hemodynamics and radiologic evaluation in addition to consultation (...) with an expert center. Surgical intervention remains the optimal management strategy. Select patients may be candidates for catheter-based intervention with balloon pulmonary angioplasty in centers with clinical expertise. Inoperable patients or those with post-intervention PH are treated with pulmonary hypertension-targeted medical therapy.Copyright © 2018 Elsevier Inc. All rights reserved.

2018 Clinics in Chest Medicine

156. Hemodynamic and Salivary Responses of 12 Weeks of Training With Different Anti-hypertensive

in 45 postmenopausal hypertensive women. Condition or disease Intervention/treatment Phase Hypertension Menopause Other: Combined exercise Not Applicable Detailed Description: Cardiovascular diseases are the leading causes of death and postmenopausal women. Physical exercise, in turn, is a strategy to reduce cardiovascular stress, by decreasing the blood pressure (BP) at rest and several risk factors associated with sedentary lifestyle, thus improving the quality and life expectancy of these women (...) ) or any event that could interfere abnormally with BP or device measurements. The device was always placed 7am and the measurements were made every 15 minutes from 7h to 23h and every 30 minutes from 23h to 7h. The monitoring was considered valid when it happened for a period of 24 hours. The following results were evaluated: systolic blood pressure; diastolic blood pressure, mean blood pressure and heart rate in awake, sleep and 24-hour periods. Before the use ABPM during daily activities, resting

2018 Clinical Trials

157. Tamoxifen Therapy to Treat Pulmonary Arterial Hypertension

Arterial Hypertension (T3PAH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03528902 Recruitment Status : Recruiting First Posted : May 18, 2018 Last Update Posted : October 12, 2018 See Sponsor: Vanderbilt University (...) Medical Center Information provided by (Responsible Party): Eric Austin, Vanderbilt University Medical Center Study Details Study Description Go to Brief Summary: The main purpose of this clinical trial is to examine the feasibility and effects of tamoxifen in subjects with pulmonary arterial hypertension (PAH). The study will evaluate how well the drug is tolerated, and its impact on functional condition and selected biomarkers. Changes in tricuspid annular plane systolic excursion (TAPSE) and other

2018 Clinical Trials

158. Ambulatory and Blood Pressure Variability Responses to Exercise in Normotensive and Hypertensive Women

Sponsor: Federal University of Uberlandia Information provided by (Responsible Party): Igor Moraes Mariano, Federal University of Uberlandia Study Details Study Description Go to Brief Summary: This study evaluated the differences between normotensive and hypertensive menopausal women in ambulatory and blood pressure variability responses to combined aerobic and resistance exercise. Condition or disease Intervention/treatment Phase Menopause Exercise Blood Pressure, High Other: Combined Exercise (...) remove one or more studies before adding more. Ambulatory and Blood Pressure Variability Responses to Exercise in Normotensive and Hypertensive Women The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03531034 Recruitment Status : Completed First Posted : May 21, 2018 Last Update Posted : May 21, 2018

2018 Clinical Trials

159. Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients With Mild to Moderate Hypertension

or 2 as defined by the European Society of Hypertension (ESH)/European Society of Cardiology (ESC) at screening; systolic blood pressure (SBP) has to be in the range of 140-179 mmHg (after 10 minutes resting in supine position, measurement in triplicate with each measurement to be within this range at screening). If the blood pressure (BP) range is not met at screening, one repeat measurement at another occasion is allowed prior to inclusion into the study. Glycated Haemoglobin A1c (HbA1c (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients With Mild to Moderate Hypertension The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03462069 Recruitment Status : Active

2018 Clinical Trials

160. The Venous Distension Reflex and Orthostatic Hypertension

Intervention Model: Parallel Assignment Intervention Model Description: The investigators will examine if individuals with elevated standing blood pressure have a heightened VDR. Two groups of subjects, "BP elevated with standing" group and "BP maintained with standing" group will be examined for this experiment. The tilt + external pressure and tilt + no external pressure, or the limb occlusion + negative pressure and limb occlusion + no negative pressure trials will be performed in random order using (...) + negative pressure performed in both "BP elevated with standing" and "BP maintained with standing" groups. Other: Limb occlusion + negative pressure In Visit 2, a cuff will be placed on the thigh of a leg that is sealed in an airtight pressure tank. After the cuff is inflated to 250 mmHg, the pressure in the tank will be reduced to -100mmHg for 2 minutes. The application of negative pressure creates a suction effect on the leg, and leads to an overall increase in pressure gradient across the blood

2018 Clinical Trials

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