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Hypertension Evaluation History

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181. Sleep Duration and Hypertension: Analysis of > 700,000 Adults by Age and Sex Full Text available with Trip Pro

Sleep Duration and Hypertension: Analysis of > 700,000 Adults by Age and Sex The objective of this study was to evaluate the cross-sectional relationship between sleep duration and hypertension in a large, nationally-representative dataset that spans 10 years. This analysis may provide detailed information with high resolution about how sleep duration is related to hypertension and how this differs by demographic group.Data were aggregated from the 2013 Behavioral Risk Factor Surveillance (...) System (n = 433,386) and the combined 2007-2016 National Health Interview Surveys (n = 295,331). These data were collected by the Centers for Disease Control and Prevention from nationally-representative samples. Surveys were combined, and survey-specific weights were used in all analyses. Sleep duration was assessed with the item, "On average, how many hours of sleep do you get in a 24-hour period?" in both surveys. Hypertension was assessed as self-reported history. Covariates were assessed

2018 Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

182. Creation of a restrictive atrial communication in pulmonary arterial hypertension (PAH): effective palliation of syncope and end-stage heart failure Full Text available with Trip Pro

Creation of a restrictive atrial communication in pulmonary arterial hypertension (PAH): effective palliation of syncope and end-stage heart failure Atrial septostomy (AS) is recommended for pulmonary arterial hypertension (PAH)-associated right ventricular (RV) failure, recurrent syncope, or pulmonary hypertensive crisis (PHC). We aimed to evaluate the feasibility and efficacy of AS to manage PAH from infancy to adulthood. From June 2009 to December 2016, transcatheter atrial communications (...) were created in 11 PAH patients (4 girls/women; median age = 4.3 years; range = 33 days-26 years; median body weight = 14 kg; range = 3-71 kg; NYHA-/Ross class IV; n = 11). PAH was classified as idiopathic (n = 6) or secondary (n = 5). History of syncope was dominant (n = 6); two with patent foramen ovale (PFO) admitted with recurrent PHC, three patients required resuscitation before AS. Three patients had PAH-associated low cardiac output. The average pulmonary arterial pressures (PAP systolic

2018 Pulmonary circulation

183. Severity of primary open-angle glaucoma in patients with hypertension and diabetes Full Text available with Trip Pro

evaluated for severity with associated risk factors.A total of 221 patients were enrolled in the study. The mean age of the patients was 54.4 (SD ± 15.9) years with a male to female ratio of 0.93:1. Of the 221 patients, 68 (31%) had a family history of POAG. Mean intraocular pressure was 15.8±4.87 mmHg, and mean central corneal thickness was 535.4±34.9 μm. A total of 81 (36%) patients had HTN, 21 (9.50%) had diabetes mellitus (DM), and 15 (6.80%) had both HTN and DM. Analysis using SPSS version 20 (...) Severity of primary open-angle glaucoma in patients with hypertension and diabetes Primary open-angle glaucoma (POAG) is a progressive optic neuropathy with numerous risk factors. Its severity with associated risk factors remains a widely debated topic.To evaluate the severity of POAG in patients with hypertension (HTN) and diabetes or both.This hospital-based, cross-sectional descriptive study was conducted for a period of 18 months from January 2016 to June 2017. Diagnosed cases of POAG were

2018 Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

184. Pregnancy‐Related Risk Factors Are Associated With a Significant Burden of Treated Hypertension Within 10 Years of Delivery: Findings From a Population‐Based Norwegian Cohort Full Text available with Trip Pro

. The burden of hypertension associated with pregnancy-related risk factors was evaluated using an attributable fraction method. A total of 1480 women developed pharmacologically treated hypertension within the follow-up among 60 027 women (rate of hypertension, 3.6/1000 person-years). The proportion of hypertension associated with a history of preeclampsia/eclampsia, gestational hypertension, preterm delivery, and pregestational or gestational diabetes mellitus was 28.6% (95% confidence interval, 25.5 (...) Pregnancy‐Related Risk Factors Are Associated With a Significant Burden of Treated Hypertension Within 10 Years of Delivery: Findings From a Population‐Based Norwegian Cohort The association between pregnancy complications and women's later cardiovascular disease has, primarily, been evaluated in studies lacking information on important covariates. This report evaluates the prospective associations between pregnancy-related risk factors (preeclampsia/eclampsia, gestational hypertension

2018 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

185. Multidisciplinary treatment of patients with diabetes and hypertension: experience of a Brazilian center Full Text available with Trip Pro

conducted this study.Data of patients with diabetes and HTN with regular follow-up visits in a multidisciplinary HTN treatment center from Brazil's Midwest were retrospectively assessed. Patients ≥ 18 years enrolled in the service by June 2017 with a minimum of three visits were included. Anthropometric, blood pressure (BP), laboratory, pharmacological treatment, lifestyle, and cardiovascular events data were collected from first (V1), intermediate (V2) and most recent (V3) visits to the service. BP (...)  < 130 × 80 mmHg, LDL-cholesterol (LDL-C) < 70 mg/dL and HbA1C < 7.0% were defined as treatment targets. Wilcoxon signed-rank test was used to compare variables along study visits. A linear regression model was built to identify variables associated with better overall patient control.A total of 162 patients were included (mean age of 56.5 ± 10.8 years). Median follow-up time was 60 (IQR 40-109) months, 80.2% of the sample was female and 83.3% had no cardiovascular event history. BP, total

2018 Diabetology & metabolic syndrome

186. Pulmonary hypertension among 5 to 18 year old children with sickle cell anaemia in Nigeria. Full Text available with Trip Pro

Pulmonary hypertension among 5 to 18 year old children with sickle cell anaemia in Nigeria. Pulmonary hypertension (PHT) is a significant cause of mortality in patients with sickle cell disease (SCD). Few studies on PHT in SCD have been carried out in children. This study aimed to estimate the prevalence of PHT in children with sickle cell anaemia (SCA) and determine its clinical and laboratory correlates.In this cross sectional study, evaluation involved obtaining bio-data, history (...) and physical examination findings in 175 SCA subjects with haemoglobin genotype SS aged 5 to 18 years and 175 age and sex matched controls with haemoglobin genotype AA. PHT was determined using peak Tricuspid Regurgitant Velocity (TRV) obtained from echocardiography as a marker. Complete blood count (CBC), lactate dehydrogenase (LDH) assay, reticulocyte count, foetal haemoglobin (HbF) estimation as well as Human Immunodeficiency Virus (HIV) I and II, Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV

2017 PLoS ONE

187. Aberrant cGMP signaling persists during recovery in mice with oxygen-induced pulmonary hypertension. Full Text available with Trip Pro

Aberrant cGMP signaling persists during recovery in mice with oxygen-induced pulmonary hypertension. Bronchopulmonary dysplasia (BPD), a common complication of preterm birth, is associated with pulmonary hypertension (PH) in 25% of infants with moderate to severe BPD. Neonatal mice exposed to hyperoxia for 14d develop lung disease similar to BPD, with evidence of associated PH. The cyclic guanosine monophosphate (cGMP) signaling pathway has not been well studied in BPD-associated PH (...) . In addition, there is little data about the natural history of hyperoxia-induced PH in mice or the utility of phosphodiesterase-5 (PDE5) inhibition in established disease. C57BL/6 mice were placed in room air or 75% O2 within 24h of birth for 14d, followed by recovery in room air for an additional 7 days (21d). Additional pups were treated with either vehicle or sildenafil for 7d during room air recovery. Mean alveolar area, pulmonary artery (PA) medial wall thickness (MWT), RVH, and vessel density were

2017 PLoS ONE

188. Effect of hypertension across the age group on survival outcomes in out-of-hospital cardiac arrest. (Abstract)

arrest registry of OHCA patients who survived to hospital admission from 2012 to 2016. The clinical histories of hypertension were obtained from patients' medical records. The endpoint was cerebral performance category (CPC) 1 and 2 (good CPC) and survival to discharge. Multivariable logistic regression analysis was performed on the data collected. The final model with an interaction term was evaluated to compare the effects of hypertension across age groups.A total 11,610 patients (61.0 (...) Effect of hypertension across the age group on survival outcomes in out-of-hospital cardiac arrest. There are few studies on the effects hypertension has on survival outcomes in out-of-hospital-cardiac arrest (OHCA) patients, although hypertension is a major risk factor for the incidence of cardiac arrest. This study aims to investigate whether hypertension is associated with survival outcomes in cardiac arrest patients across age groups.This study was conducted using the national cardiac

2018 American Journal of Emergency Medicine

189. Coagulation Activation by Hyperosmolar Agents in Intracranial Hypertension

. Coagulation Activation by Hyperosmolar Agents in Intracranial Hypertension The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03409237 Recruitment Status : Not yet recruiting First Posted : January 24, 2018 Last Update Posted (...) : September 21, 2018 See Sponsor: Neuromed IRCCS Information provided by (Responsible Party): Licia Iacoviello, Neuromed IRCCS Study Details Study Description Go to Brief Summary: Osmotherapy consists in the therapeutic use of osmotically active substances with the aim of reducing the volume and therefore the intracranial pressure. It therefore represents an essential component in the clinical management of cerebral edema and intracranial hypertension, whether they are a consequence of head trauma

2018 Clinical Trials

190. Adrenal Artery Ablation for Uncontrolled Hypertension

hypertension and activation of RAAS have to take spironolactone or other antihypertensive drugs for long time. On the other side, long-term inhibition of aldosterone receptor may cause hyperkalemia, male breast hyperplasia and other adverse reactions. Moreover, hyperaldosterone is still not corrected by spironolactone, which causes extensive cerebrovascular damages even though blood pressure and blood potassium had been normalized. With the development of adrenal vein sampling and adrenal ablation (...) , selective arterial ablation of adrenal gland(AAA) was observed with significant decrease of blood aldosterone and blood pressure in patients with PA, which made it promising that uncontrolled hypertension could be relieved by selective AAA. Condition or disease Intervention/treatment Phase Uncontrolled Hypertension Procedure: Selective endovascular chemical ablation of adrenal gland Drug: Traditional triple antihypertensive treatment Phase 3 Study Design Go to Layout table for study information Study

2018 Clinical Trials

191. Prenatal Mindfulness & Hypertension Study

mindfulness training is an acceptable intervention among pregnant women with histories of hypertensive disorders of pregnancy. 20 pregnant women with histories of hypertensive disorders of pregnancy will be randomly picked to participate in an 8-week phone-delivered mindfulness training intervention (N=10) or usual care (N=10). All women will undergo blood pressure monitoring before and after the intervention. The investigators predict that phone-delivered mindfulness training will reduce risk (...) Bublitz, Lifespan Study Details Study Description Go to Brief Summary: Hypertensive disorders of pregnancy are one of the greatest causes of death to mothers and babies. These disorders affect 1 out of every 10 pregnancies, the rate is increasing in the United States, and rate of recurrence is as high as 50%. Treatments to prevent hypertensive disorders of pregnancy from happening in future pregnancies are limited. There are currently no effective interventions to prevent hypertension recurrence

2018 Clinical Trials

192. Effects of DHEA in Pulmonary Hypertension

Effects of DHEA in Pulmonary Hypertension Effects of DHEA in Pulmonary Hypertension - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects of DHEA in Pulmonary Hypertension (EDIPHY) The safety (...) and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03648385 Recruitment Status : Recruiting First Posted : August 27, 2018 Last Update Posted : January 17, 2019 See Sponsor: Rhode Island Hospital Information provided by (Responsible Party

2018 Clinical Trials

193. Hypertensive Pregnant Women Monitored by Teletransmitted Self-measurements of Blood Pressure

studies before adding more. Hypertensive Pregnant Women Monitored by Teletransmitted Self-measurements of Blood Pressure (FETH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03648645 Recruitment Status : Not yet (...) ). It is therefore essential to diagnose AH with certainty in order to set-up appropriate care and follow its evolution. Condition or disease Intervention/treatment Phase Hypertension in Pregnancy Device: Self measurement of blood pressure Other: Standard follow-up consultation in the hospital Not Applicable Detailed Description: The objective of this study is to show the interest of self-measurement with teletransmission for long-term follow-up of hypertensive pregnant women (at high risk of preeclampsia

2018 Clinical Trials

194. A Randomized Trial Comparing Oral Misoprostol Alone With Oral Misoprostol Followed by Oxytocin in Women Induced for Hypertension of Pregnancy

this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Randomized Trial Comparing Oral Misoprostol Alone With Oral Misoprostol Followed by Oxytocin in Women Induced for Hypertension of Pregnancy (MOLI) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk (...) A Randomized Trial Comparing Oral Misoprostol Alone With Oral Misoprostol Followed by Oxytocin in Women Induced for Hypertension of Pregnancy A Randomized Trial Comparing Oral Misoprostol Alone With Oral Misoprostol Followed by Oxytocin in Women Induced for Hypertension of Pregnancy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save

2018 Clinical Trials

195. Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine

) and uncontrolled patients on mono, dual or triple antihypertensive therapy with systolic blood pressure (SBP) from 140 mmHg or higher AND/OR diastolic blood pressure (DBP) from 90 mmHg or higher (SBP ≥ 140 AND/OR DBP ≥ 85 mmHg for patients with type 2 diabetes mellitus) will be invited to participate in this study. During 16-week trial, seven study visits are planned. At first study visit physical examination, medical history, BP measurement, electrocardiogram (ECG), laboratory analysis and of Ambulatory Blood (...) for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by KRKA: Hypertension Blood pressure control Fixed-dose combination antihypertensives Ambulatory blood pressure monitoring Additional relevant MeSH terms: Layout table for MeSH terms Hypertension Vascular Diseases Cardiovascular Diseases Amlodipine Perindopril Indapamide Antihypertensive Agents Calcium Channel Blockers Membrane Transport Modulators Molecular Mechanisms

2018 Clinical Trials

196. A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension

of human immunodeficiency virus infection-associated PAH Prior exposure to sotatercept (ACE-011) or luspatercept (ACE-536) Uncontrolled systemic hypertension as evidenced by sitting systolic BP > 160 mm Hg or sitting diastolic BP > 100 mm Hg during Screening after a period of rest Systolic BP < 90 mm Hg during Screening or at baseline History of known pericardial constriction History of personal or family history of long QTc syndrome or sudden cardiac death History of restrictive or constrictive (...) . A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (SPECTRA) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03738150 Recruitment Status : Recruiting First Posted : November 12, 2018 Last Update

2018 Clinical Trials

197. Effects of Preoperative Operating Room Environment Presentation in Hypertensive Patients

: December 4, 2018 Last Verified: December 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Nureddin YUZKAT, Yuzuncu Yıl University: Hypertensive patients Introduction of operating room Anxiety Blood pressure Additional relevant MeSH terms: Layout table for MeSH terms Anxiety Disorders Mental Disorders (...) Information provided by (Responsible Party): Nureddin YUZKAT, Yuzuncu Yıl University Study Details Study Description Go to Brief Summary: The aim of this study was to investigate the effects of preoperative operating room environment introduction on preoperative hypertension and blood pressure in hypertensive patients. Condition or disease Intervention/treatment Phase Hypertension Anxiety Blood Pressure Behavioral: Group IORE Not Applicable Detailed Description: Procedure to be Applied: In order

2018 Clinical Trials

198. Primary Technology Enhanced Care in Hypertension

: Ministry of Health, Singapore Information provided by (Responsible Party): Valerie Teo, National Healthcare Group Polyclinics Study Details Study Description Go to Brief Summary: This study evaluates the impact of the use of a technology-enabled home blood pressure monitor amongst hypertensive patients in primary care. Half of the patients will receive the blood pressure monitor for home monitoring, while the other half will receive usual care at the polyclinic. The hypothesis is tele-monitoring along (...) , or have a family member who is willing to assist in using telemedicine for blood pressure control Clinic teams who are directly involved in patient care Exclusion Criteria: Patients who have cognitive impairment Pregnant patients Patients with hypertension and other chronic illnesses other than hyperlipidemia, such as diabetes. Patients with a history of ischemic heart disease, congestive heart failure, stroke, transient ischemic attack, atrial fibrillation and renal impairment. Contacts and Locations

2018 Clinical Trials

199. Prognostic Implications of Mitral Annular Plane Systolic Excursion in Patients with Hypertension and a Clinical Indication for Cardiac Magnetic Resonance Imaging: A Multicenter Study. (Abstract)

Prognostic Implications of Mitral Annular Plane Systolic Excursion in Patients with Hypertension and a Clinical Indication for Cardiac Magnetic Resonance Imaging: A Multicenter Study. This study sought to evaluate the prognostic value of cardiac magnetic resonance (CMR)-derived mitral annular plane systolic excursion (MAPSE) in a large multicenter population of patients with hypertension.In patients with hypertension, cardiac abnormalities are powerful predictors of adverse outcomes. Long-axis (...) ). Lateral MAPSE was independently associated with death among the subgroups of patients with preserved ejection fraction (HR = 1.339; p < 0.001) and in those without history of myocardial infarction (HR: 1.390; p < 0.001).CMR-derived lateral MAPSE is a powerful, independent predictor of mortality in patients with hypertension and a clinical indication for CMR, incremental to common clinical and CMR risk factors. These findings may suggest a role for CMR-derived lateral MAPSE in identifying hypertensive

2018 JACC. Cardiovascular imaging

200. Abstract 79: Chronic and Acute Hypertension in Ischemic Stroke Are Distinct Markers of Impaired Collateral Circulation. (Abstract)

Abstract 79: Chronic and Acute Hypertension in Ischemic Stroke Are Distinct Markers of Impaired Collateral Circulation. Acute blood pressure (BP) elevation in acute ischemic stroke (AIS) is common, yet the link with collateral circulation remains elusive due to lack of longitudinal data on premorbid hypertension (HTN) and serial BP changes within an individual. Precision medicine for AIS and management of HTN requires an understanding of collateral circulation.The Interventional Management (...) in those with both history of HTN and acutely elevated BP.Chronic and acute HTN are both potent predictors of impaired collaterals in AIS. Understanding how HTN affects the structure and function of collaterals and response to acute BP changes is critical for future hypertensive management and collateral augmentation.

2018 Stroke

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