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Hypertension Evaluation

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1. Evaluation and Treatment of Asymptomatic Hypertension

Evaluation and Treatment of Asymptomatic Hypertension Evaluation and Treatment of Asymptomatic Hypertension | Emergency Medicine | Washington University in St. Louis Open Menu Back Close Menu Search for: Loading... Welcome Our Team Sections Education Alumni Research ECRC Journal Club Events Jermyn Lectures Open Search Vignette You are working an evening shift in The Deuce when your next patient is roomed—a 53-year-old African American woman whose chief complaint is elevated blood pressure. She (...) . PICO Question Population: Patients presenting to the emergency department (ED) with severely elevated BP and no signs or symptoms concerning for end-organ damage Intervention: Laboratory testing, electrocardiogram (ECG), chest x-ray, rapid reduction blood pressure, initiation of antihypertensive agents upon discharge Comparison: Outpatient referral for evaluation and initiation of antihypertensive therapy Outcome: Sroke, MI, renal failure, dialysis, death Search Strategy PudMed was searched

2019 Washington University Emergency Medicine Journal Club

2. Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses). (PubMed)

Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses). Plasma renin is an important regulator of blood pressure (BP). Plasma renin activity (PRA) has been shown to correlate with variability in BP response to antihypertensive agents. We conducted a genome-wide association study to identify single-nucleotide polymorphisms (SNPs) associated with baseline PRA using data from the PEAR study (...) (Pharmacogenomic Evaluation of Antihypertensive Responses).Multiple linear regression analysis was performed in 461 whites and 297 blacks using an additive model, adjusting for age, sex, and ancestry-specific principal components. Top SNPs were prioritized by testing the expected direction of association for BP response to atenolol and hydrochlorothiazide. Top regions from the BP response prioritization were tested for functional evidence through differences in gene expression by genotype using RNA sequencing

2019 Circulation. Genomic and precision medicine Controlled trial quality: uncertain

3. Hypertension Canada's 2018 guidelines for the management of hypertension in pregnancy

to minimize bias. Hypertension Canada’s guideline process has been externally reviewed and is in concordance with the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument for guideline development (guidelines.hypertension.ca/about/overview-process). 7 The Hypertension Canada Guidelines Committee (HCGC) is comprised of a multidisciplinary panel of content as well as methodological experts divided into 16 subgroups in distinct areas of hypertension (see Supplemental Appendix S1 (...) hypertension (systolic blood pressure 160 mmHgand/ordiastolicbloodpressure110mmHg)requiresurgent antihypertensive therapy to reduce maternal, fetal, and newborn adverse outcomes. The speci?c evidence and rationale underlying each of these guidelines are discussed. hypertendues pendant leur grossesse. Les lignes directrices relatives au diagnostic, à l’ evaluation, à la pr evention et au traitement de l’hy- pertension chez l’adulte et l’enfant sont publi ees s epar ement. Dans ces premières lignes

2018 CPG Infobase

4. Resistant Hypertension: Insights on Evaluation and Management in the Post-SPRINT (Systolic Blood Pressure Intervention Trial) Era.

Resistant Hypertension: Insights on Evaluation and Management in the Post-SPRINT (Systolic Blood Pressure Intervention Trial) Era. 27600177 2018 01 26 2018 01 26 1524-4563 68 5 2016 11 Hypertension (Dallas, Tex. : 1979) Hypertension Resistant Hypertension: Insights on Evaluation and Management in the Post-SPRINT (Systolic Blood Pressure Intervention Trial) Era. 1073-1080 Townsend Raymond R RR From the Perelman School of Medicine, University of Pennsylvania, Philadelphia; and Division (...) of Nephrology and Hypertension, University of Miami Miller School of Medicine, FL. townsend@upenn.edu. Epstein Murray M From the Perelman School of Medicine, University of Pennsylvania, Philadelphia; and Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, FL. eng Comparative Study Journal Article Meta-Analysis Research Support, Non-U.S. Gov't Review 2016 09 06 United States Hypertension 7906255 0194-911X 0 Antihypertensive Agents IM Adult Aged Antihypertensive Agents

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2018 Hypertension (Dallas, Tex. : 1979)

5. Socioeconomic Status and Hypertension Control in Sub-Saharan Africa: The Multination EIGHT Study (Evaluation of Hypertension in Sub-Saharan Africa). (PubMed)

Socioeconomic Status and Hypertension Control in Sub-Saharan Africa: The Multination EIGHT Study (Evaluation of Hypertension in Sub-Saharan Africa). Systemic hypertension is a rapidly growing epidemic in Africa. The role of socioeconomic status on blood pressure control has not been well studied in this part of the world. We, therefore, aimed to quantify the association of socioeconomic status both at the individual and at the country level with blood pressure control in Sub-Saharan Africa. We (...) conducted a cross-sectional survey in urban clinics of 12 countries, both low income and middle income, in Sub-Saharan Africa. Standardized blood pressure measures were made among the hypertensive patients attending the clinics. Blood pressure control was defined as blood pressure <140/90 mm Hg, and hypertension grades were defined according to the European Society of Cardiology guidelines. A total of 2198 hypertensive patients (58.4±11.8 years; 39.9% men) were included. Uncontrolled hypertension

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2018 Hypertension

6. Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Synopsis of the 2017 American College of Cardiology/American Heart Association Hypertension Guideline. (PubMed)

Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Synopsis of the 2017 American College of Cardiology/American Heart Association Hypertension Guideline. In November 2017, the American College of Cardiology (ACC) and the American Heart Association (AHA) released a clinical practice guideline for the prevention, detection, evaluation, and treatment of high blood pressure (BP) in adults. This article summarizes the major recommendations.In 2014, the ACC (...) and the AHA appointed a multidisciplinary committee to update previous reports of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The committee reviewed literature and commissioned systematic reviews and meta-analyses on out-of-office BP monitoring, the optimal target for BP lowering, the comparative benefits and harms of different classes of antihypertensive agents, and the comparative benefits and harms of initiating therapy with a single

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2018 Annals of Internal Medicine

7. Diagnosis & Assessment of Hypertension - Renovascular Hypertension

Diagnosis & Assessment of Hypertension - Renovascular Hypertension VII. Assessment for Renovascular Hypertension | Hypertension Canada Guidelines Subgroup Members: Marcel Ruzicka, MD PhD; Sheldon W. Tobe, MD MScCH; Ramesh Prasad, MBBS MSc MA PhD; Michel Vallée, MD PhD; Cedric Edwards, MD Central Review Committee: Stella S. Daskalopoulou, MD MSc DIC PhD (Chair); Kaberi Dasgupta, MD MSc; Kelly B. Zarnke, MD MSc; Kara Nerenberg, MD, MSc; Alexander A. Leung, MD MPH; Kevin C. Harris, MD MHSc; Kerry (...) McBrien, MD MPH; Sonia Butalia, BSc MD MSc; Meranda Nakhla, MD MSc Co-Chairs: Doreen M. Rabi, MD MSc, Stella S. Daskalopoulou, MD MSc DIC PhD This information is based on the Hypertension Canada guidelines published in Nerenberg, Kara A. et al. Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. . Guidelines Patients presenting with ≥ 2 of the following clinical clues listed below, suggesting renovascular hypertension

2018 Hypertension Canada

8. Diagnosis & Assessment of Hypertension - Endocrine Hypertension

Diagnosis & Assessment of Hypertension - Endocrine Hypertension VIII. Assessment For Endocrine Hypertension | Hypertension Canada Guidelines Subgroup Members: Ally P.H. Prebtani, MD; Gregory Kline, MD, Ernesto L. Schiffrin, MD PhD; Andrew Don-Wauchope, MD Central Review Committee: Stella S. Daskalopoulou, MD MSc DIC PhD (Chair); Kaberi Dasgupta, MD MSc; Kelly B. Zarnke, MD MSc; Kara Nerenberg, MD, MSc; Alexander A. Leung, MD MPH; Kevin C. Harris, MD MHSc; Kerry McBrien, MD MPH; Sonia Butalia (...) , BSc MD MSc; Meranda Nakhla, MD MSc Co-Chairs: Doreen M. Rabi, MD MSc, Stella S. Daskalopoulou, MD MSc DIC PhD This information is based on the Hypertension Canada guidelines published in Nerenberg, Kara A. et al. Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. . Guidelines Hyperaldosteronism: screening and diagnosis Screening for hyperaldosteronism should be considered in hypertensive patients

2018 Hypertension Canada

9. A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients

A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information (...) . Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does

2018 Clinical Trials

10. Hierarchical Modeling of Patient and Physician Determinants of Blood Pressure Outcomes in Hypertensive Patients with and without Diabetes: Pooled Analysis of Six Observational Valsartan Studies with 15,282 Evaluable Patients (PubMed)

Hierarchical Modeling of Patient and Physician Determinants of Blood Pressure Outcomes in Hypertensive Patients with and without Diabetes: Pooled Analysis of Six Observational Valsartan Studies with 15,282 Evaluable Patients We pooled data from 6 valsartan-related studies including 3,658 diabetic and 11,624 nondiabetic patients to evaluate blood pressure (BP) outcomes after approximately 90 days of second- or later-line valsartan treatment. Hierarchical linear and logistic regressions were (...) included age, BP at diagnosis of hypertension, risk factors, valsartan regimen, concomitant antihypertensive treatment, and adherence; and physician-related determinants included gender, years in practice, and hypertension management. In summary, in both diabetic and nondiabetic patients, the use of valsartan-centric treatment regimens in second- or later-line antihypertensive treatment is associated with significant reductions in BP level and improvement in BP control. The determinants identified

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2017 International journal of chronic diseases

11. Evaluating the relationship of blood pressure, plasma angiotensin peptides and aldosterone with cognitive functions in patients with hypertension (PubMed)

Evaluating the relationship of blood pressure, plasma angiotensin peptides and aldosterone with cognitive functions in patients with hypertension Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the relationship of blood pressure control, plasma angiotensin peptides and aldosterone with cognitive (...) functions. Forty-one patients who were under treatment with the same antihypertensive medications for at least three months were included in the study. Plasma angiotensin II, angiotensin 1-7, angiotensin IV, and aldosterone concentrations were analyzed using an enzyme-linked immunosorbent assay (ELISA). Standardized Mini Mental State Examination (SMMSE) was used to evaluate cognitive functions. When the participants were grouped according to their SMMSE scores (cut-off value: 26 points), we determined

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2017 EXCLI journal

12. An individual patient-level meta-analysis to assess the prognostic role of the echocardiographic evaluation of right ventricular function in pulmonary arterial hypertension: the TAPSE PAH (TransAtlantic Prognostic Studies on Echocardiography in Pulmonary

An individual patient-level meta-analysis to assess the prognostic role of the echocardiographic evaluation of right ventricular function in pulmonary arterial hypertension: the TAPSE PAH (TransAtlantic Prognostic Studies on Echocardiography in Pulmonary Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied

2019 PROSPERO

13. Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy: Executive Summary

Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy: Executive Summary Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy: Executive Summary - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 36, Issue 5, Pages 416–438 Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy: Executive Summary PRINCIPAL AUTHORS, x Laura A. Magee , MD (...) : disseminated intravascular coagulation; DbM: diabetes mellitus; LV: left ventricle Abstract Objective This executive summary presents in brief the current evidence assessed in the clinical practice guideline prepared by the Canadian Hypertensive Disorders of Pregnancy Working Group and published by Pregnancy Hypertension ( ) to provide a reasonable approach to the diagnosis, evaluation, and treatment of the hypertensive disorders of pregnancy. Evidence Published literature was retrieved through searches

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2014 Society of Obstetricians and Gynaecologists of Canada

14. Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy: Executive Summary

Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy: Executive Summary 404 Toggle navigation Toggle search Keyword search language Keyword search 404 Error Page/Asset Not Found The Society of Obstetricians and Gynaecologists of Canada (SOGC) {1} {1} {1}

2014 Society of Obstetricians and Gynaecologists of Canada

15. Noninvasive cardiovascular imaging for evaluating subclinical target organ damage in hypertensive patients: a consensus article from the European Association of Cardiovascular Imaging, the European Society of Cardiology Council on Hypertension and the Eur (PubMed)

Noninvasive cardiovascular imaging for evaluating subclinical target organ damage in hypertensive patients: a consensus article from the European Association of Cardiovascular Imaging, the European Society of Cardiology Council on Hypertension and the Eur : Arterial hypertension accounts for the largest amount of attributable cardiovascular mortality worldwide, and risk stratification in hypertensive patients is of crucial importance to manage treatment and prevent adverse events. Asymptomatic (...) involvement of different organs in patients affected by hypertension represents an independent determinant of cardiovascular risk, and the identification of target organ damage is recommended to further reclassify patients' risk. Noninvasive cardiovascular imaging is progressively being used and continues to provide new technological opportunities to target organ damage evaluation at early stage. The aim of this article is to provide the community of cardiology with an update on appropriate and justified

2017 Journal of Hypertension

16. Post-discharge evaluation of medication adherence and knowledge of hypertension among hypertensive stroke patients in northwestern China (PubMed)

Post-discharge evaluation of medication adherence and knowledge of hypertension among hypertensive stroke patients in northwestern China The aims of this study were to assess the knowledge of hypertension (HTN) and investigate risk factors associated with medication adherence among hypertensive stroke patients after discharge in northwestern China.A cross-sectional study involving 440 Chinese hypertensive stroke patients was conducted in a tertiary hospital in Xi'an, China. Data were collected (...) by telephone interviews and patients' medical records.It was found that 35.23% of patients were compliant with their antihypertensive drug treatments, and 42.95%, 52.27% and 4.77% of patients had poor, moderate and adequate knowledge of HTN, respectively. Gender, blood pressure (BP) categories, BP monitoring and HTN knowledge were independently associated with antihypertensive medication adherence.The medication adherence among hypertensive stroke patients in northwestern China was poor. Knowledge of HTN

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2017 Patient preference and adherence

17. Hypertension Canada's 2016 Canadian Hypertension Education Program guidelines for pharmacists: an update

Hypertension Canada's 2016 Canadian Hypertension Education Program guidelines for pharmacists: an update CPJ/RPC • november / december 2016 • VOL 149, NO 6 337 © The Author(s) 2016 DOI: 10.1177/1715163516671747 Practice guidelines Peer-reviewed Practice guidelines * Peer-reviewed 671747 CPHXXX10.1177/1715163516671747C P J / R P CC P J / R P C research-article2016 Hypertension Canada’s 2016 Canadian Hypertension Education Program guidelines for pharmacists: An update Yazid N. Al Hamarneh, BSc (...) (Pharm), PhD; Sherilyn K. D. Houle, BSP , PhD; Raj Padwal, MD, MSc; Ross T. Tsuyuki, BSc(Pharm), PharmD, MSc, FCSHP , FACC The Canadian Hypertension Education Program (CHEP) has been preparing and pub- lishing guidelines for diagnosis and management of hypertension since 1999. 1 The 2016 guide- lines, 2 released earlier this year, mark the 18th yearly production and update of evidence to date in the area of hypertension. Those guidelines, among other Hypertension Canada activities, can be considered

2016 CPG Infobase

18. Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension

Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension Prognostication is important when counseling patients and defining treatment strategies in pulmonary arterial hypertension (PAH).To determine the value of magnetic resonance imaging (MRI) metrics for prediction of mortality in PAH.Consecutive patients with PAH undergoing MRI were identified from the ASPIRE (Assessing the Spectrum of Pulmonary Hypertension Identified at a Referral Centre (...) ) pulmonary hypertension registry.During the follow-up period of 42 (range, 17-142) months 576 patients were studied and 221 (38%) died. A derivation cohort (n = 288; 115 deaths) and validation cohort (n = 288; 106 deaths) were identified. We used multivariate Cox regression and found two independent MRI predictors of death (P < 0.01): right ventricular end-systolic volume index adjusted for age and sex, and the relative area change of the pulmonary artery. A model of MRI and clinical data constructed

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2017 EvidenceUpdates

19. Evaluating pre-pregnancy dietary diversity vs. dietary quality scores as predictors of gestational diabetes and hypertensive disorders of pregnancy. (PubMed)

Evaluating pre-pregnancy dietary diversity vs. dietary quality scores as predictors of gestational diabetes and hypertensive disorders of pregnancy. Dietary diversity scores (DDS) are considered as metrics for monitoring the implementation of the UN's Sustainable Development Goals, but they need to be rigorously evaluated.To examine two DDS, the Food Groups Index (FGI), and the Minimum Dietary Diversity-Women (MDD-W), alongside two dietary quality scores, the Alternate Healthy Eating Index (...) (AHEI-2010) and the Prime Diet Quality Score (PDQS), with risks of gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy (HDPs).The analysis included 21,312 (GDM) and 19,917 (HDPs) singleton births reported in the Nurses' Health Study II cohort (1991-2001), among women without major chronic disease or GDM/HDPs. Scores were derived using prepregnancy diet collected by a comprehensive food frequency questionnaire. Multivariable models were utilized to calculate relative risks (RR

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2018 PLoS ONE

20. A prospective evaluation of the diagnostic accuracy of the physical examination for pulmonary hypertension. (PubMed)

A prospective evaluation of the diagnostic accuracy of the physical examination for pulmonary hypertension. The utility of physical examination findings for pulmonary hypertension (PH) is not well established. The purpose of this study was to prospectively evaluate the diagnostic performance of the physical examination for detecting PH.Consecutive patients undergoing right heart catheterization (n=116) were examined by an attending physician, medical resident and medical student in a blinded

2019 Chest

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