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Hypertension Causes

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2. Treatment of Secondary Hypertension Due to Endocrine Causes

Treatment of Secondary Hypertension Due to Endocrine Causes XIV. Treatment of Secondary Hypertension Due to Endocrine Causes | Hypertension Canada Guidelines Subgroup Members: Ally P.H. Prebtani, MD; Gregory Kline, MD, Ernesto L. Schiffrin, MD PhD; Andrew Don-Wauchope, MD Central Review Committee: Stella S. Daskalopoulou, MD MSc DIC PhD (Chair); Kaberi Dasgupta, MD MSc; Kelly B. Zarnke, MD MSc; Kara Nerenberg, MD, MSc; Alexander A. Leung, MD MPH; Kevin C. Harris, MD MHSc; Kerry McBrien, MD MPH (...) ; Sonia Butalia, BSc MD MSc; Meranda Nakhla, MD MSc Co-Chairs: Doreen M. Rabi, MD MSc, Stella S. Daskalopoulou, MD MSc DIC PhD This information is based on the Hypertension Canada guidelines published in Nerenberg, Kara A. et al. Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. . Recommendations Treatment of hyperaldosteronism and pheochromocytoma are outlined in , respectively. Background Treatment

2018 Hypertension Canada

3. Adherence to dietary approaches to stop hypertension and all-cause and cause-specific mortality: a dose-response meta-analysis of prospective cohort studies

Adherence to dietary approaches to stop hypertension and all-cause and cause-specific mortality: a dose-response meta-analysis of prospective cohort studies Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith

2018 PROSPERO

4. Whom should you test for secondary causes of hypertension?

Whom should you test for secondary causes of hypertension? Whom should you test for secondary causes of hypertension? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Whom should you test for secondary causes of hypertension? View/ Open Date 2014-01 Format Metadata Abstract Evidence-based answer: It’s recommended (...) that all children and adolescents with a new diagnosis of hypertension undergo renal ultrasound and laboratory evaluation for renal pathology (strength of recommendation [SOR]: C, consensus-based guidelines). Specific diagnostic tests are recommended for newly diagnosed patients who have suspicious clinical findings suggestive of a secondary cause of hypertension based on the initial history (excess daytime sleepiness, palpitations, tremor, sweating); physical examination (abdominal bruit, thyromegaly

2014 Clinical Inquiries

5. Detection of Secondary Causes and Coexisting Diseases in Hypertensive Patients: OSA and PA Are the Common Causes Associated with Hypertension (PubMed)

Detection of Secondary Causes and Coexisting Diseases in Hypertensive Patients: OSA and PA Are the Common Causes Associated with Hypertension Since the control rate of blood pressure is lower in mainland China, the aim of this study is to investigate the proportion of secondary causes and coexisting diseases of hypertension in hypertensive patients.Data on consecutive patients with hypertension who visited the Hypertension Center. Diseases were detected using an established strict screening (...) protocol.Detection rate of secondary causes and coexisting diseases of hypertension was 39.5% among 3003 hypertensive patients. Obstructive sleep apnea (OSA) was the most common, accounting for 24.7% of patients, followed by primary aldosteronism (PA) (5.8%) and PA + OSA (4.9%). Endocrine hypertension accounted for 12.1% of patients, including 10.7% of patients with PA, 1.1% with hypothyroidism, 0.1% with pheochromocytoma, 0.1% with Cushing's syndrome, and 0.1% with hyperthyroidism, respectively. Those who smoke

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2017 BioMed research international

6. Associations of marital status with diabetes, hypertension, cardiovascular disease and all-cause mortality: A long term follow-up study. (PubMed)

Associations of marital status with diabetes, hypertension, cardiovascular disease and all-cause mortality: A long term follow-up study. To investigate the associations of marital status with major clinical outcomes including type 2 diabetes (T2D), hypertension, cardiovascular disease (CVD) and all-cause mortality.The study cohort (1999-2014) included 9,737 (45% male) Iranian adults with a mean age of 47.6 years. Marital status was defined as married versus never married, divorced and widowed (...) . The relationship between marital status and the four above mentioned outcomes were investigated using Cox regression models adjusted for the main confounders, specific to each outcome.After more than 12 years of follow-up, 1,889 (883 men) individuals developed hypertension, 1,038 (468 men) T2D, 1015 (597 men) CVD and 668 (409 men) all-cause mortality. Compared with married, being never married in men was associated with higher risk of hypertension [hazard ratio (HR): 1.55; 95% confidence interval (CI), 1.11

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2019 PLoS ONE

7. Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model. (PubMed)

Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model. Right ventricular (RV) myocardial dysfunction is a common feature in septic shock. It can worsen outcome, but the etiology is poorly understood. Pulmonary artery hypertension (PAH) plays a part in the pathogenesis of the right heart dysfunction in sepsis but its importance is unknown. In pigs, PAH in sepsis is substantial and the translational value of porcine sepsis models (...) therefore questioned. We hypothesized that porcine sepsis causes a myocardial inflammatory response which leads to myocardial dysfunction independent of PAH.Sepsis was induced by Escherichia coli-infusion in 10 pigs resulting in PAH and increased right ventricular pressure (RVP). The same degree of RVP was achieved by external pulmonary artery banding (PAB) in a consecutive series of 6 animals.Sepsis, but not PAB, led to increase in endothelial damage marker PAI-1 and cytokines TNF and IL-6 (all p<0.05

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2019 PLoS ONE

8. Hypertensive Crisis and Refractory Hypertension Caused by Atypical Hemolytic Uremic Syndrome and Effect of Eculizumab (PubMed)

Hypertensive Crisis and Refractory Hypertension Caused by Atypical Hemolytic Uremic Syndrome and Effect of Eculizumab 30271097 2018 11 14 1011-6842 34 5 2018 Sep Acta Cardiologica Sinica Acta Cardiol Sin Hypertensive Crisis and Refractory Hypertension Caused by Atypical Hemolytic Uremic Syndrome and Effect of Eculizumab. 446-449 10.6515/ACS.201809_34(5).20180326D Chen Fan-Yu FY Department of Medicine. Chen Chen-Huan CH Department of Medicine. Department of Medical Education, Taipei Veterans

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2018 Acta Cardiologica Sinica

9. What is the clinical and cost effectiveness of interventions to monitor for intracranial hypertension or vasospasm in adults with a confirmed subarachnoid haemorrhage caused by a ruptured aneurysm?

What is the clinical and cost effectiveness of interventions to monitor for intracranial hypertension or vasospasm in adults with a confirmed subarachnoid haemorrhage caused by a ruptured aneurysm? Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears

2019 PROSPERO

10. Detecting cerebrovascular changes in the brain caused by hypertension in atrial fibrillation group using acoustocerebrography. (PubMed)

Detecting cerebrovascular changes in the brain caused by hypertension in atrial fibrillation group using acoustocerebrography. Acoustocerebrography is a novel, non-invasive, transcranial ultrasonic diagnostic method based on the transmission of multispectral ultrasound signals propagating through the brain tissue. Dedicated signal processing enables the estimation of absorption coefficient, frequency-dependent attenuation, speed of sound and tissue elasticity. Hypertension and atrial (...) fibrillation are well known factors correlated with white matter lesions, intracerebral hemorrhage and cryptogenic stroke numbers. The aim of this study was to compare the acoustocerebrography signal in the brains of asymptomatic atrial fibrillation patients with and without hypertension. The study included 97 asymptomatic patients (40 female and 57 male, age 66.26 ± 6.54 years) who were clinically monitored for atrial fibrillation. The patients were divided into two groups: group I (patients

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2018 PLoS ONE

11. Diagnosis & Assessment of Hypertension - Renovascular Hypertension

treatment option for renovascular disease. However, early studies showed that revascularization led to cure of hypertension in only in a small number of patients. In the subgroup of patients who did not respond at all to revascularization, it is probable that the renal artery stenosis was not severe enough to cause renovascular hypertension. In those with only a partial response to revascularization, renal artery stenosis likely played only a partial role in the maintenance of hypertension (...) ). Fibromuscular dysplasia primarily affects younger (<40 year old) females. As the prevalence of hypertension below age 40 is relatively low, the presence of hypertension at this age more likely indicates either secondary form of hypertension and/or use of drugs/substances causing high blood pressure. In this situation, especially in the absence of an obvious contributor to early onset hypertension (such as obesity), testing for renovascular hypertension appears justified, as fibromuscular dysplasia

2018 Hypertension Canada

12. Diagnosis & Assessment of Hypertension - Endocrine Hypertension

A. Hyperaldosteronism: screening and diagnosis An excess of aldosterone as a cause for hypertension (primary aldosteronism) has traditionally been considered relatively rare (approximately 1% of hypertensive patients). However, recent studies using improved diagnostic methods have suggested that forms of hyperaldosteronism are much more prevalent, perhaps occurring in up to 15.5% of hypertensive patients and even 1.5% of normotensive subjects . Primary aldosteronism, is often caused by an aldosterone-producing (...) , and the need for multiple drug therapy . Blood pressure lowering responses to other potassium-sparing diuretics, ACEIs, ARBs and calcium channel blockers are modest-to-moderate . B. Pheochromocytoma and Paraganglioma: screening and diagnosis Pheochromocytomas and paragangliomas (PPGL) are an infrequent cause of hypertension (less than 0.3%) . The prevalence is greater among patients with adrenal incidentaloma (4%) . Because of the low incidence of pheochromocytoma/PPGL, the significant risk of severe

2018 Hypertension Canada

13. Correction to: Neonatal hypertension: cases, causes, and clinical approach. (PubMed)

Correction to: Neonatal hypertension: cases, causes, and clinical approach. The original version of this article unfortunately contained a mistake. Due to a production error, the wrong "Key summary points" were included. The correct key summary points are listed below.

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2019 Pediatric Nephrology

14. A successful pregnancy in a patient with secondary hypertension caused by adrenal adenoma: a case report. (PubMed)

A successful pregnancy in a patient with secondary hypertension caused by adrenal adenoma: a case report. Secondary hypertension is a rare complication in pregnancy that causes poor outcomes, such as preeclampsia, premature delivery, intrauterine growth retardation, stillbirths, spontaneous abortion or intrauterine death. Cushing's disease caused by an adrenal adenoma is rare during pregnancy and may be overlooked by obstetricians and physicians, but can lead to hypertension, diabetes mellitus (...) and an increased risk of fetal and maternal morbidity. Approximately 200 cases have been reported in the literature. Here, we report the successful management of a pregnant patient with Cushing's syndrome due to an adrenal adenoma.The 35-year-old Chinese female had no individual or family medical history of hypertension, and did not exhibit chronic kidney disease, diabetes mellitus, autoimmune and common endocrine diseases. Her blood pressure was elevated from the 16th week of gestation and was not controlled

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2019 BMC Pregnancy and Childbirth

15. Unhealthy changes in eating habits cause acute onset hypertension in the normotensive community-dwelling elderly-3 years cohort study. (PubMed)

Unhealthy changes in eating habits cause acute onset hypertension in the normotensive community-dwelling elderly-3 years cohort study. The aim of this study was to determine what lifestyle changes can predict acute onset hypertension in the normotensive community-dwelling elderly.This study targeted elderly people enrolled in National Health Insurance in Fukushima Prefecture, Japan. The subjects were 24,490 people who took all of the specific health examination conducted by National Health (...) Insurance in fiscal years 2013, 2014, and 2015 continuously and had a recorded systolic blood pressure (BP) <130 mm Hg and diastolic BP <85 mm Hg in the first 2 fiscal years. We examined their lifestyle changes for the first 2 fiscal years using the questionnaires given at the health examination. Multivariate Poisson regression analysis was conducted to examine the relationship between new-onset hypertension observed at the last examination and unhealthy lifestyle changes.The mean age of the subjects

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2019 Medicine

16. Is resistant hypertension an independent predictor of all-cause mortality in individuals with type 2 diabetes? A prospective cohort study. (PubMed)

Is resistant hypertension an independent predictor of all-cause mortality in individuals with type 2 diabetes? A prospective cohort study. Resistant hypertension is independently associated with an increased risk of death in the general hypertensive population. We assessed whether resistant hypertension is an independent predictor of all-cause mortality in individuals with type 2 diabetes from the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicentre Study.On 31 October 2015 (...) analyses were used to assess the association with all-cause mortality.Using the 130/80 mmHg targets for categorization, crude mortality rates and Kaplan-Meier estimates were highest among resistant hypertension participants, especially those with controlled resistant hypertension. As compared with resistant hypertension, risk for all-cause mortality was significantly lower for all the other groups, including individuals with controlled hypertension (hazard ratio 0.81 [95% confidence interval 0.74-0.89

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2019 BMC Medicine

17. Severe Arterial Hypertension from Cullin 3 Mutations Is Caused by Both Renal and Vascular Effects. (PubMed)

Severe Arterial Hypertension from Cullin 3 Mutations Is Caused by Both Renal and Vascular Effects. Mutations in four genes, WNK lysine deficient protein kinase 1 and 4 (WNK1 and WNK4), kelch like family member 3 (KLHL3), or Cullin 3 (CUL3), can result in familial hyperkalemic hypertension (FHHt), a rare Mendelian form of human arterial hypertension. Although all mutations result in an increased abundance of WNK1 or WNK4, all FHHt-causing CUL3 mutations, resulting in the skipping of exon 9, lead (...) involved in regulation of vascular tone, compared with aortas from control mice. We also observed increased RhoA abundance and t1/2 in Cul3∆9-expressing cells, caused by decreased ubiquitination.Mutations in Cul3 cause severe hypertension by affecting both renal and vascular function, the latter being associated with activation of RhoA.Copyright © 2019 by the American Society of Nephrology.

2019 Journal of the American Society of Nephrology

18. An Unusual Cause of Pulmonary Arterial Hypertension: Hydatid Cyst. (PubMed)

An Unusual Cause of Pulmonary Arterial Hypertension: Hydatid Cyst. Hydatid cyst is an important health problem throughout the world and it is caused by the larval form of Echinococcus granulosus. Although it is most commonly located in the liver and lungs, hydatid cyst can also affect other organs because the oncospheres spread through the bloodstream. The disease may have many different clinical presentations. Although it is a benign disease, sometimes it can cause serious morbidity and even (...) mortality. Here, the case of a 33-year-old male patient who underwent surgery for a right ventricle and bilateral lung hydatid cyst 9 years ago and had pulmonary hypertension is presented.Copyright © 2019. Published by Elsevier Inc.

2019 Annals of Thoracic Surgery

19. Risks of cause-specific mortality in offspring of pregnancies complicated by hypertensive disease of pregnancy. (PubMed)

Risks of cause-specific mortality in offspring of pregnancies complicated by hypertensive disease of pregnancy. Fetal environment has a substantial influence on an individual's health throughout their life course. Animal models of hypertensive disease of pregnancy have demonstrated adverse health outcomes among offspring exposed to hypertensive disease of pregnancy in utero. Although there are numerous descriptions of the neonatal, infant, and pediatric outcomes of human offspring affected (...) , or eclampsia. Offspring from these pregnancies (exposed) were matched to offspring of pregnancies without hypertensive disease of pregnancy (unexposed) by maternal age at delivery, birth year, sex, and multiple gestation. We also identified unexposed siblings of exposed offspring for a separate sibling analysis. Mortality follow-up of all offspring continued through 2016, at which time they would have been 49-69 years old. Adjusted hazard ratios for cause-specific mortality comparing exposed with unexposed

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2019 American Journal of Obstetrics and Gynecology

20. Pulmonary arterial hypertension caused by congenital extrahepatic portocaval shunt: a case report. (PubMed)

Pulmonary arterial hypertension caused by congenital extrahepatic portocaval shunt: a case report. Congenital extrahepatic portocaval shunt (CEPS), also known as Abernethy malformation, is an extremely rare anomaly of the splanchnic venous system, especially when accompanied by pulmonary arterial hypertension.We report a case of a 15-year-old female who was diagnosed with CEPS (Abernethy type Ib) accompanied by pulmonary arterial hypertension. This case was incidentally identified during (...) abdominal ultrasound examination and confirmed by mesenteric and splenic arteriography. During more than 4 years of follow-up, after receiving sildenafil (80 mg/day), the patient's condition improved in the first year after discharge. However, one year later, the patient's conditions start to deteriorate.This article presents a rare case of Abernethy malformation accompanied by pulmonary arterial hypertension, which can be diagnosed by using abdominal ultrasonography, portal vein computed tomography

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2019 BMC Cardiovascular Disorders

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