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Hyperpigmentation

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141. Postinflammatory Hyperpigmentation (Overview)

Postinflammatory Hyperpigmentation (Overview) Postinflammatory Hyperpigmentation: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2OTE5MS1vdmVydmlldw== processing (...) > Postinflammatory Hyperpigmentation Updated: May 04, 2018 Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Postinflammatory Hyperpigmentation Overview Background Postinflammatory hyperpigmentation (PIH) is a frequently encountered problem and represents the sequelae of various cutaneous disorders as well as therapeutic interventions. [ ] This acquired excess of pigment can be attributed to various preceding disease processes that affect

2014 eMedicine.com

142. Postinflammatory Hyperpigmentation (Follow-up)

Postinflammatory Hyperpigmentation (Follow-up) Postinflammatory Hyperpigmentation Treatment & Management: Medical Care, Surgical Care, Prevention Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2OTE5MS10cmVhdG1lbnQ= processing > Postinflammatory Hyperpigmentation Treatment & Management Updated: May 04, 2018 Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Postinflammatory Hyperpigmentation Treatment Medical Care The treatment of postinflammatory hyperpigmentation (PIH) tends to be a difficult and prolonged process that often takes 6-12 months to achieve the desired results of depigmentation. Each of these treatment options potentially

2014 eMedicine.com

143. Postinflammatory Hyperpigmentation (Diagnosis)

Postinflammatory Hyperpigmentation (Diagnosis) Postinflammatory Hyperpigmentation: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2OTE5MS1vdmVydmlldw== processing (...) > Postinflammatory Hyperpigmentation Updated: May 04, 2018 Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Postinflammatory Hyperpigmentation Overview Background Postinflammatory hyperpigmentation (PIH) is a frequently encountered problem and represents the sequelae of various cutaneous disorders as well as therapeutic interventions. [ ] This acquired excess of pigment can be attributed to various preceding disease processes that affect

2014 eMedicine.com

144. Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. (Abstract)

Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. Skin lightening preparations are used by people all over the world for a diverse range of dermatologic indications. Hydroquinone (HQ) is the gold standard and remains the only prescription product available in the United States for the treatment of generalized facial hyperpigmentation. Irritation and the risk of exogenous (...) and distribution. A single-center, double-blind comparison clinical study of 18 subjects was conducted to evaluate the efficacy of the product in reducing ultraviolet-induced hyperpigmentation. Test sites were irradiated with 1.0, 1.5, 2.0, and 2.5 minimal erythema doses. After 5 days, to allow for pigmentation development, the product or 4% HQ cream was applied to the respective test sites, once daily for 4 weeks. Chroma Meter measurements (L* brightness) and standardized digital photographs were taken

2013 Journal of drugs in dermatology : JDD Controlled trial quality: uncertain

145. Generalized hyperpigmentation in Wilson's disease: An unusual association Full Text available with Trip Pro

Generalized hyperpigmentation in Wilson's disease: An unusual association Wilson's disease, an autosomal recessive disorder of copper metabolism, most commonly presents either with hepatic or neurological features. But, it may sometimes have certain atypical presentations posing diagnostic difficulties. We report here a case of Wilson's disease presenting with generalized hyperpigmentation of skin who also developed neurological manifestations subsequently. We aim to highlight the importance (...) of keeping Wilson's disease as one of the differentials in patients who present with hyperpigmentation and neurological symptoms compatible with copper deposits in the central nervous system and proceed for investigations accordingly.

2013 Journal of neurosciences in rural practice

146. Secondary hyperpigmentation during interferon alfa treatment for chronic hepatitis C virus infection. Full Text available with Trip Pro

Secondary hyperpigmentation during interferon alfa treatment for chronic hepatitis C virus infection. Interferon alfa remains the central treatment for chronic hepatitis C virus (HCV) infection. Cases of cutaneous and mucous hyperpigmentations during interferon alfa treatment have been reported, but they are considered rare adverse effects.To study the clinical presentation and frequency of hyperpigmentation in patients receiving interferon alfa treatment for chronic HCV infection.Prospective (...) with hyperpigmentation. Hyperpigmentation of the oral mucous membrane, acquired longitudinal melononychia, and hyperpigmentation of the face were each observed in 7 patients (9%). All patients with hyperpigmentation of the skin had skin type III or IV and worked outside without sun protection. The intensity of pigmentation was reported to decrease progressively when interferon treatment was discontinued. Most patients with hyperpigmentation of the oral mucosa also had melanonychia. However, patients

2013 JAMA dermatology (Chicago, Ill.)

147. Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. (Abstract)

Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. Skin lightening preparations are used by people all over the world for a diverse range of dermatologic indications. Hydroquinone (HQ) is the gold standard and remains the only prescription product available in the United States for the treatment of generalized facial hyperpigmentation. Irritation and the risk of exogenous (...) and distribution. A single-center, double-blind comparison clinical study of 18 subjects was conducted to evaluate the efficacy of the product in reducing ultraviolet-induced hyperpigmentation. Test sites were irradiated with 1.0, 1.5, 2.0, and 2.5 minimal erythema doses. After 5 days, to allow for pigmentation development, the product or 4% HQ cream was applied to the respective test sites, once daily for 4 weeks. Chroma Meter measurements (L* brightness) and standardized digital photographs were taken

2013 Journal of drugs in dermatology : JDD Controlled trial quality: uncertain

148. Efficacy and Safety of Biocellulose Sheet Containing Anti-hyperpigmentation Agent ("Biocellulose Mask", "Farhorm®") in Patients Receiving Laser Treatment

Efficacy and Safety of Biocellulose Sheet Containing Anti-hyperpigmentation Agent ("Biocellulose Mask", "Farhorm®") in Patients Receiving Laser Treatment Efficacy and Safety of Biocellulose Sheet Containing Anti-hyperpigmentation Agent ("Biocellulose Mask", "Farhorm®") in Patients Receiving Laser Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail (...) Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Efficacy and Safety of Biocellulose Sheet Containing Anti-hyperpigmentation Agent ("Biocellulose Mask", "Farhorm®") in Patients Receiving Laser Treatment The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government

2013 Clinical Trials

149. Facial hyperpigmentation: causes and treatment. (Abstract)

Facial hyperpigmentation: causes and treatment. By midcentury, the U.S.A. will be more ethnically and racially diverse. Skin of colour will soon constitute nearly one-half of the U.S. population, and a full understanding of skin conditions that affect this group is of great importance. Structural and functional differences in the skin, as well as the influence of cultural practices, produce variances in skin disease and presentation based on skin type. In the skin of colour population (...) , dyschromia is a growing concern, and a top chief complaint when patients present to the physician. A thorough understanding of the aetiology and management strategies of facial hyperpigmentation is of importance in caring for those afflicted and also in the development of new therapies. © 2013 The Authors BJD © 2013 British Association of Dermatologists.

2013 British Journal of Dermatology

150. Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study. Full Text available with Trip Pro

Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study. Axillary hyperpigmentation is a frequent cause of cosmetic consultations in dark-skinned women from tropical areas, including Latin America. Currently, there is no widely accepted treatment for the disorder, but it is usually treated with bleaching agents because it is considered a variant of inflammatory hyperpigmentation. The purpose of this study (...) was performed by histochemistry and immunohistochemistry, assisted by computerized morphometric analysis.Both niacinamide and desonide induced significant colorimetric improvement compared with placebo; however, desonide showed a better depigmenting effect than niacinamide. A good to excellent response was achieved in 24% of cases for niacinamide, 30% for desonide, and 6% for placebo. We observed a marked disruption of the basal membrane in axillary hyperpigmentation and an inflammatory infiltrate

2013 Clinical, cosmetic and investigational dermatology Controlled trial quality: uncertain

151. Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. (Abstract)

Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation. Skin lightening preparations are used by people all over the world for a diverse range of dermatologic indications. Hydroquinone (HQ) is the gold standard and remains the only prescription product available in the United States for the treatment of generalized facial hyperpigmentation. Irritation and the risk of exogenous (...) and distribution. A single-center, double-blind comparison clinical study of 18 subjects was conducted to evaluate the efficacy of the product in reducing ultraviolet-induced hyperpigmentation. Test sites were irradiated with 1.0, 1.5, 2.0, and 2.5 minimal erythema doses. After 5 days, to allow for pigmentation development, the product or 4% HQ cream was applied to the respective test sites, once daily for 4 weeks. Chroma Meter measurements (L* brightness) and standardized digital photographs were taken

2013 Journal of drugs in dermatology : JDD

152. Tolerance and efficacy of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison with 4% hydroquinone. (Abstract)

Tolerance and efficacy of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison with 4% hydroquinone. Hydroquinone (HQ) is the benchmark prescription agent for skin lightening. However, HQ use is recently banned in Europe and in parts of Asia because of potential long-term consequences, including carcinogenesis when orally consumed. This has resulted in development of alternative skin-lightening agents with comparable efficacy to HQ

2013 Journal of drugs in dermatology : JDD Controlled trial quality: uncertain

153. Pain and Hyperpigmentation of the Toes: A Quiz. Full Text available with Trip Pro

Pain and Hyperpigmentation of the Toes: A Quiz. 23756605 2014 09 11 2014 02 26 1651-2057 94 2 2014 Mar Acta dermato-venereologica Acta Derm. Venereol. Pain and hyperpigmentation of the toes: a quiz. Hyperpigmentation of the toes caused by millipedes. 253-4 10.2340/00015555-1645 Sampaio Felipe Maurício Soeiro FM Department of Dermatology, Oswaldo Cruz Foudation, 21940210 Rio de Janeiro, Brazil. felipemauricio@uol.com.br. Valviesse Vitor Ribeiro Gomes de Almeida VR Lyra-da-Silva Julia Ocampo JO (...) Mesquita Emerson Cicilini EC Brandão Luciana Gomes Pedro LG do Valle Antonio Carlos Francesconi AC eng Case Reports Journal Article Sweden Acta Derm Venereol 0370310 0001-5555 IM Animals Arthropods Bites and Stings complications Brazil Female Humans Hyperpigmentation etiology Pain etiology Toes Young Adult 2013 6 13 6 0 2013 6 13 6 0 2014 9 12 6 0 ppublish 23756605 10.2340/00015555-1645

2013 Acta Dermato-Venereologica

154. A Novel Germline KIT Mutation (p.L576P) in a Family Presenting With Juvenile Onset of Multiple Gastrointestinal Stromal Tumors, Skin Hyperpigmentations, and Esophageal Stenosis. (Abstract)

A Novel Germline KIT Mutation (p.L576P) in a Family Presenting With Juvenile Onset of Multiple Gastrointestinal Stromal Tumors, Skin Hyperpigmentations, and Esophageal Stenosis. Familial gastrointestinal stromal tumor (GIST) syndrome is a rare autosomal dominant genetic disorder. We report on a kindred in which 3 family members carry a germline mutation (c.1727T>C, p.L576P) in exon 11 of the KIT gene. This mutation was not reported so far in familial GISTs. Apart from multiple GISTs in 2

2013 American Journal of Surgical Pathology

155. Hyperpigmentation: types, diagnostics and targeted treatment options. (Abstract)

Hyperpigmentation: types, diagnostics and targeted treatment options. Pigment formation is highly complex. It is involved in inflammation, sun protection and many other processes. For practical purposes, such as exposure time for sun tanning, six skin types are distinguished according to Fitzpatrick, listed in decreasing lightness. The hyperpigmentation commonly occurs in Fitzpatrick skin types III to VI and can have a considerable impact on quality of life.In this article we will give

2013 Journal of the European Academy of Dermatology and Venereology

156. A focused review on acne-induced and aesthetic procedure-related postinflammatory hyperpigmentation in Asians. (Abstract)

A focused review on acne-induced and aesthetic procedure-related postinflammatory hyperpigmentation in Asians. Postinflammatory hyperpigmentation (PIH) is a common consequence following cutaneous inflammation in dark-skinned individuals with Fitzpatrick skin phototypes (SPTs) III-VI. The exact pathogenesis of this condition is unknown, but is believed to be an integral part of the normal response of the skin to inflammatory stimuli. PIH can last from months to years and may significantly impair

2013 Journal of the European Academy of Dermatology and Venereology

157. 4-n-butylresorcinol, a highly effective tyrosinase inhibitor for the topical treatment of hyperpigmentation. Full Text available with Trip Pro

4-n-butylresorcinol, a highly effective tyrosinase inhibitor for the topical treatment of hyperpigmentation. Hyperpigmentary disorders like melasma, actinic and senile lentigines are a major cosmetic concern. Therefore, many topical products are available, containing various active ingredients aiming to reduce melanin production and distribution. The most prominent target for inhibitors of hyperpigmentation is tyrosinase, the key regulator of melanin production. Many inhibitors of tyrosinase (...) , 4-n-butylresorcinol reduced visibly the appearance of age spots, while the control spots showed no improvement. A second study showed that 4-butylresorcinol was more effective than 4-hexylresorcinol and 4-phenylethylresorcinol.The present in vitro and in vivo data prove the high inhibitory capacity of 4-n-butylresorcinol on human tyrosinase activity, exceeding by far the potency of hydroquinone, arbutin and kojic acid. The resulting clinical improvement of skin hyperpigmentations reveals 4-n

2013 Journal of the European Academy of Dermatology and Venereology

158. Diltiazem-Associated Hyperpigmentation Full Text available with Trip Pro

Diltiazem-Associated Hyperpigmentation 23846341 2014 08 12 2018 11 13 1525-1497 28 12 2013 Dec Journal of general internal medicine J Gen Intern Med Diltiazem-associated hyperpigmentation. 1676 10.1007/s11606-013-2530-1 Campbell Michelle M Wayne State University School of Medicine, Detroit, MI, USA. Ahluwalia Jesleen J Watson Alice C AC eng Case Reports Journal Article 2013 07 12 United States J Gen Intern Med 8605834 0884-8734 0 Antihypertensive Agents EE92BBP03H Diltiazem IM Antihypertensive (...) Agents adverse effects Diltiazem adverse effects Female Humans Hyperpigmentation chemically induced diagnosis Middle Aged 2012 11 15 2013 06 10 2013 01 31 2013 7 13 6 0 2013 7 13 6 0 2014 8 13 6 0 ppublish 23846341 10.1007/s11606-013-2530-1 PMC3832732 J Dermatol. 2010 Sep;37(9):807-11 20883365 Dermatol Online J. 2011;17(7):14 21810399 Cutis. 2010 Aug;86(2):82-4 20919601

2013 Journal of General Internal Medicine

159. Mixed hyperpigmentation and hypopigmentation of iris and choroid in Chediak-Higashi syndrome. (Abstract)

Mixed hyperpigmentation and hypopigmentation of iris and choroid in Chediak-Higashi syndrome. An 8-year-old Taiwanese girl presented with hyperpigmentation and scattered hypopigmentation in her irides and choroids. Her skin showed hyperpigmentation with speckled hypopigmentation over cheeks and sun-exposed areas. Medical history was remarkable for frequent infectious episodes and lower extremity bruising. A peripheral blood smear revealed large inclusion bodies in the cytoplasm of neutrophils

2013 JAAPOS - Journal of the American Association for Pediatric Ophthalmology and Strabismus

160. Postinflammatory Hyperpigmentation

Postinflammatory Hyperpigmentation Postinflammatory Hyperpigmentation Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Postinflammatory (...) Hyperpigmentation Postinflammatory Hyperpigmentation Aka: Postinflammatory Hyperpigmentation From Related Chapters II. Definition response to inflammation on dark skin III. Pathophysiology Common complication following or inflammation in darker skin type (3 to 6) Local inflammation results in prostaglandin, leukotriene and thromboxane release Epidermal s hypertrophy, synthesizing IV. Causes: Common precipitating lesions Inflammation Laser therapy or V. Signs Irregular, dark s and patches at sites of injury

2015 FP Notebook

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