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Hyperpigmentation

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81. Hyperpigmentation in Pregnancy

Hyperpigmentation in Pregnancy Hyperpigmentation in Pregnancy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Hyperpigmentation (...) in Pregnancy Hyperpigmentation in Pregnancy Aka: Hyperpigmentation in Pregnancy , Chadwick's Sign , Linea Nigra II. Physiology stimulating hormone rises in early pregnancy Increased deposition III. Signs: General Scarred areas and nevi darken Pigmented areas become more pigmented Areola Axilla External genitalia Anal region Linea Nigra IV. Signs: Specific Chadwick's Sign Darkened vulva and vagina or ( ) Dark areas under eyes and bridge nose Linea Nigra Dark midline low Images: Related links to external

2018 FP Notebook

82. Diffuse Hyperpigmentation

Diffuse Hyperpigmentation Diffuse Hyperpigmentation Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Diffuse Hyperpigmentation Diffuse (...) Hyperpigmentation Aka: Diffuse Hyperpigmentation , Melanism , Diffuse Hypermelanosis , Melanosis From Related Chapters II. Causes Excessive deposition: Excessive s: Phototoxic III. Signs Diffuse brown discoloration of skin pigmentation Accentuated areas Palmar creases Recent scars Pressure points at elbow, knee, and knuckles IV. Differential Diagnosis Localized Lesions (increased or s) See See Diffuse skin changes See See See Images: Related links to external sites (from Bing) These images are a random sampling

2018 FP Notebook

83. Hyperpigmentation

Hyperpigmentation Hyperpigmentation Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Hyperpigmentation Hyperpigmentation Aka (...) : Hyperpigmentation From Related Chapters II. Causes: Hyperpigmentation Localized Lesions (increased or s) See See s Diffuse skin changes See See See See systemic causes below III. Causes: Systemic conditions with Hyperpigmentation Skin Endocrine and Metabolic See ( Deposition) Porphyria Hemosiderin deposition in Gastrointestinal Disease Whipple's Disease ( deposition) Genitalia Heller-Nelson Syndrome Hematology and Oncology Neoplasm Nutrition Starvation Medications and toxins See (increased s) Images: Related

2018 FP Notebook

84. Medication Causes of Hyperpigmentation

Medication Causes of Hyperpigmentation Medication Causes of Hyperpigmentation Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Medication Causes of Hyperpigmentation Medication Causes of Hyperpigmentation Aka: Medication Causes of Hyperpigmentation , Hyperpigmentation Due to Medication , Drug Induced Hyperpigmentation From Related Chapters II. Causes ( ) Bismuth Bleomycin Busulfan Clofazimine Cyclophosphamide Daunorubicin Dibromomannitol Doxorubicin Gold Topical nitrogen mustard Phenothiazines Silver Zodovudine III. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing

2018 FP Notebook

85. Oral Mucosa Hyperpigmentation

Oral Mucosa Hyperpigmentation Oral Mucosa Hyperpigmentation Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Oral Mucosa (...) Hyperpigmentation Oral Mucosa Hyperpigmentation Aka: Oral Mucosa Hyperpigmentation , Melanin Pigmentation of Oral Mucosa From Related Chapters II. Causes May be associated with in autoimmune polyendocrinopathy- -ectodermal dystrophy syndrome Darker pigmentation related to ethnicity abuse 1 McCune-Albright Syndrome Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Oral Mucosa Hyperpigmentation." Click on the image (or right click) to open

2018 FP Notebook

86. Postinflammatory Hyperpigmentation Associated with Treatment of Solar Lentigines using a Q-Switched 532-nm Nd: YAG Laser: A Multicenter Survey. (Abstract)

Postinflammatory Hyperpigmentation Associated with Treatment of Solar Lentigines using a Q-Switched 532-nm Nd: YAG Laser: A Multicenter Survey. To characterize the risk factors of Korean patients for postinflammatory hyperpigmentation (PIH) during treatment of solar lentigines using a Q-switched 532-nm Nd: YAG (QS 532 NY) laser.The present retrospective multicenter study was conducted at the dermatology clinics of five tertiary hospitals in Korea. Between October 2007 and January 2013, 516

2016 Journal of Dermatological Treatment

87. Hyperpigmentation following the Blaschko's lines: a subtle cutaneous manifestation of Turner syndrome with complex mosaicism. (Abstract)

Hyperpigmentation following the Blaschko's lines: a subtle cutaneous manifestation of Turner syndrome with complex mosaicism. 27106053 2017 09 18 2017 09 18 1365-2133 175 6 2016 Dec The British journal of dermatology Br. J. Dermatol. Hyperpigmentation following the Blaschko's lines: a subtle cutaneous manifestation of Turner syndrome with complex mosaicism. 1379-1381 10.1111/bjd.14688 Deza G G Department of Dermatology, Department of Pathology, Hospital del Mar - Parc de Salut Mar, Barcelona (...) , Spain. Cancer Research Programme, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. Gilaberte M M Department of Dermatology, Department of Pathology, Hospital del Mar - Parc de Salut Mar, Barcelona, Spain. Pujol R M RM Department of Dermatology, Department of Pathology, Hospital del Mar - Parc de Salut Mar, Barcelona, Spain. eng Case Reports Letter 2016 10 07 England Br J Dermatol 0004041 0007-0963 IM Child, Preschool Female Humans Hyperpigmentation etiology pathology Mosaicism

2016 British Journal of Dermatology

88. Edema, Hyperpigmentation, Induration: 3 Skin Signs Heralding Danger in Patients on Maintenance Hemodialysis. (Full text)

Edema, Hyperpigmentation, Induration: 3 Skin Signs Heralding Danger in Patients on Maintenance Hemodialysis. Skin changes are common in patients on dialysis. This study focused on putative associations of specific skin findings with comorbidities and mortality.We performed a retrospective analysis of data from 508 patients on maintenance hemodialysis therapy in 7 centers in the German State of North Rhine Westphalia. Data had been collected by interview, from patient files, and from targeted (...) physical examination in an earlier prospective study screening hemodialysis patients for the presence of nephrogenic systemic fibrosis. While on dialysis, patients' extremities had been examined for any of the following: edematous skin at the lower extremities, hyperpigmentation, induration, and xerosis cutis. Our present data analyses focused on associated mortality and comorbidities.Five hundred eight patients (median age 71 years, range 20.0-95.9; n = 292 men) had agreed to participate

2016 Medicine PubMed abstract

89. Treatment of Persistent Facial Postinflammatory Hyperpigmentation With Novel Pulse-in-Pulse Mode Intense Pulsed Light. (Abstract)

Treatment of Persistent Facial Postinflammatory Hyperpigmentation With Novel Pulse-in-Pulse Mode Intense Pulsed Light. Postinflammatory hyperpigmentation (PIH) is an acquired hypermelanosis induced by various causes including inflammatory dermatoses, injury, or cosmetic procedures, such as lasers or chemical peels, and it tends to affect dark-skinned people with greater frequency and severity. There are a variety of treatment options for PIH, including topical agents, chemical peels, laser

2016 Dermatologic Surgery

90. The comparison between modified kligman formulation versus kligman formulation and intense pulsed light in the treatment of the post-burn hyperpigmentation. (Full text)

The comparison between modified kligman formulation versus kligman formulation and intense pulsed light in the treatment of the post-burn hyperpigmentation. Post inflammatory hyperpigmentation (PIH) is a common problem occurs following many dermatologic diseases and medical interventions. Different modalities including topical agents, lasers and intense pulsed light (IPL) are suggested for treatment of the post-burn PIH. In the current study, we evaluated the efficacy of IPL plus modified

2016 Advanced biomedical research Controlled trial quality: uncertain PubMed abstract

91. Minocycline-induced Hyperpigmentation (Full text)

Minocycline-induced Hyperpigmentation 27173498 2019 01 28 2019 01 28 1525-1497 32 1 2017 01 Journal of general internal medicine J Gen Intern Med Minocycline-induced Hyperpigmentation. 133 10.1007/s11606-016-3735-x Judson Timothy T Department of Internal Medicine, University of California, San Francisco, CA, USA. Mihara Kip K Emergency Department, San Francisco VA Medical Center, 4150 Clement Street, Mail code 111A3, San Francisco, CA, 94121, USA. Kip.mihara@va.gov. Department of Internal (...) Medicine, University of California, San Francisco, CA, USA. Kip.mihara@va.gov. eng Case Reports Journal Article 2016 05 12 United States J Gen Intern Med 8605834 0884-8734 0 Anti-Bacterial Agents FYY3R43WGO Minocycline IM Aged Anti-Bacterial Agents administration & dosage adverse effects Diagnosis, Differential Drug-Related Side Effects and Adverse Reactions diagnosis etiology Humans Hyperpigmentation chemically induced diagnosis Male Minocycline administration & dosage adverse effects Patient Care

2016 Journal of General Internal Medicine PubMed abstract

92. Periorbital Hyperpigmentation: A Comprehensive Review (Full text)

Periorbital Hyperpigmentation: A Comprehensive Review Periorbital hyperpigmentation is a commonly encountered condition. There is very little scientific data available on the clinical profile and pathogenesis of periorbital hyperpigmentation. Periorbital hyperpigmentation is caused by various exogenous and endogenous factors. The causative factors include genetic or heredity, excessive pigmentation, postinflammatory hyperpigmentation secondary to atopic and allergic contact dermatitis (...) , periorbital edema, excessive vascularity, shadowing due to skin laxity and tear trough associated with aging. There are a number of treatment options available for periorbital hyperpigmentation. Among the available alternatives to treat dark circles are topical depigmenting agents, such as hydroquinone, kojic acid, azelaic acid, and topical retinoic acid, and physical therapies, such as chemical peels, surgical corrections, and laser therapy, most of which are tried scientifically for melasma, another

2016 The Journal of clinical and aesthetic dermatology PubMed abstract

93. Anti-Melanogenic Potentials of Nanoparticles from Calli of Resveratrol-Enriched Rice against UVB-Induced Hyperpigmentation in Guinea Pig Skin (Full text)

Anti-Melanogenic Potentials of Nanoparticles from Calli of Resveratrol-Enriched Rice against UVB-Induced Hyperpigmentation in Guinea Pig Skin We already reported that genetically engineered resveratrol-enriched rice (RR) showed to down-regulate skin melanogenesis. To be developed to increase the bioactivity of RR using calli from plants, RR was adopted for mass production using plant tissue culture technologies. In addition, high-pressure homogenization (HPH) was used to increase (...) the biocompatibility and penetration of the calli from RR into the skin. We aimed to develop anti-melanogenic agents incorporating calli of RR (cRR) and nanoparticles by high-pressure homogenization, examining the synergistic effects on the inhibition of UVB-induced hyperpigmentation. Depigmentation was observed following topical application of micro-cRR, nano-calli of normal rice (cNR), and nano-cRR to ultraviolet B (UVB)-stimulated hyperpigmented guinea pig dorsal skin. Colorimetric analysis, tyrosinase

2016 Biomolecules & therapeutics PubMed abstract

94. An Unusual Case of Facial Hyperpigmentation Solved on Histopathology (Full text)

An Unusual Case of Facial Hyperpigmentation Solved on Histopathology 27790561 2018 11 13 2249-782X 10 9 2016 Sep Journal of clinical and diagnostic research : JCDR J Clin Diagn Res An Unusual Case of Facial Hyperpigmentation Solved on Histopathology. WL01-WL02 Agarwal Kiran K Director Professor, Department of Pathology, Lady Hardinge Medical College , New Delhi, India . Puri Vandana V Assistant Professor, Department of Pathology, Lady Hardinge Medical College , New Delhi, India . Goel Ruchika

2016 Journal of clinical and diagnostic research : JCDR PubMed abstract

95. Hyperpigmentation in a middle aged woman: a common yet underdiagnosed condition (Full text)

Hyperpigmentation in a middle aged woman: a common yet underdiagnosed condition 27406454 2016 07 13 2018 11 13 2000-9666 6 3 2016 Journal of community hospital internal medicine perspectives J Community Hosp Intern Med Perspect Hyperpigmentation in a middle aged woman: a common yet underdiagnosed condition. 31544 10.3402/jchimp.v6.31544 Melnick Stephen S Department of Internal Medicine, Reading Health System, West Reading, PA, USA; Stephen.melnick2@readinghealth.org. Lohani Saroj S Department

2016 Journal of community hospital internal medicine perspectives PubMed abstract

96. Mitten-Line Hyperpigmentation of an Infant (Full text)

Mitten-Line Hyperpigmentation of an Infant 27746653 2018 11 13 1013-9087 28 5 2016 Oct Annals of dermatology Ann Dermatol Mitten-Line Hyperpigmentation of an Infant. 653-654 Park Jin J Department of Dermatology, Chonbuk National University Medical School, Jeonju, Korea.; Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea. Park Su-Kyung SK Department of Dermatology, Chonbuk National

2016 Annals of dermatology PubMed abstract

97. Unusual case of hyperpigmentation secondary to irinotecan (Full text)

Unusual case of hyperpigmentation secondary to irinotecan 27793873 2017 03 06 2018 12 02 1757-790X 2016 2016 Oct 28 BMJ case reports BMJ Case Rep Unusual case of hyperpigmentation secondary to irinotecan. bcr2016217545 10.1136/bcr-2016-217545 Nestor Laura Aisling LA Department of Dermatology, Adelaide and Meath Hospital, Tallaght, Ireland. Flint Stephen S Department of Oral Medicine and Dentistry, Dublin Dental School and Hospital, Dublin, Ireland. Galvin Sheila S Department of Oral Medicine (...) & dosage Colorectal Neoplasms therapy Drug Eruptions etiology Female Humans Hyperpigmentation chemically induced Irinotecan Middle Aged Mouth Mucosa Nails Neoplasm Recurrence, Local drug therapy Conflicts of Interest: None declared. 2016 10 30 6 0 2017 3 7 6 0 2016 10 30 6 0 epublish 27793873 bcr-2016-217545 10.1136/bcr-2016-217545 PMC5093355 Drug Discov Today Dis Mech. 2008;5(2):e189-e199 19578486 J Pharm Bioallied Sci. 2015 Aug;7(Suppl 2):S403-8 26538887

2016 BMJ case reports PubMed abstract

98. Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation (Full text)

Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation Hyperpigmentation caused by melanin overproduction is a major skin disorder in humans. Inhibition of tyrosinase, a key regulator of melanin production, has been used as an effective strategy to treat hyperpigmentation. In this study, we investigated the use of solid lipid nanoparticles (SLNs) as a highly effective and nontoxic means to deliver (...) -induced melanogenesis, resulting in no change in the skin color of C57BL/6 mouse, compared with that observed in an MHY solution-treated group and an untreated control group. The antimelanogenic effect of MHY-SLNs was further confirmed through Fontana-Masson staining. Importantly, MHY-SLNs did not induce any toxic effects in the L929 cell line. Overall, these data indicate that MHY-SLNs show promise in the topical treatment of hyperpigmentation.

2016 Drug design, development and therapy PubMed abstract

99. Minocycline-Induced Cutaneous Hyperpigmentation in an Orthopedic Patient Population (Full text)

Minocycline-Induced Cutaneous Hyperpigmentation in an Orthopedic Patient Population Background.  The objectives of this study were to estimate the incidence and evaluate risk factors for development of minocycline-induced cutaneous hyperpigmentation in patients with orthopedic infections. Methods.  Patients with orthopedic infections evaluated at Mayo Clinic (Rochester, MN) and treated with minocycline from 1 January 2002 to 31 December 2011 were retrospectively identified. Long-term (...) minocycline suppression was defined as daily minocycline use for at least 3 months. A proportional hazards model was used to evaluate potential risk factors. Results.  Of 291 patients receiving long-term minocycline suppression, 54% (156 of 291) developed hyperpigmentation after a mean follow-up of 4.8 years (range, 0.3-13.2 years); 88% involved blue-gray pigmentation of normal skin that appeared most commonly in the lower (75%) and upper extremities (44%). The mean duration of minocycline therapy before

2016 Open forum infectious diseases PubMed abstract

100. Tigecycline Induced Hyperpigmentation of the Skin (Full text)

Tigecycline Induced Hyperpigmentation of the Skin 27011952 2016 03 25 2018 11 13 2328-8957 3 1 2016 Jan Open forum infectious diseases Open Forum Infect Dis Tigecycline Induced Hyperpigmentation of the Skin. ofw033 10.1093/ofid/ofw033 Vandecasteele S J SJ Departments of Nephrology and Infectious Diseases. De Ceulaer J J Maxillofacial Surgery. Wittouck E E Dermatology , AZ Sint-Jan Brugge-Oostende AV , Belgium. eng Journal Article 2016 02 17 United States Open Forum Infect Dis 101637045 2328

2016 Open forum infectious diseases PubMed abstract

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