How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

2,860 results for

Hyperpigmentation

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

41. Particular hyperpigmentation of the soft palate Full Text available with Trip Pro

Particular hyperpigmentation of the soft palate 30061965 2018 10 01 2018 10 01 1937-8688 29 2018 The Pan African medical journal Pan Afr Med J Particular hyperpigmentation of the soft palate. 187 10.11604/pamj.2018.29.187.15110 Casu Cinzia C Private Dental Practice, Cagliari, Italy. Viganò Luca L University of Milan, Department of Radiology, Milano, Italy. eng Case Reports Journal Article 2018 04 02 Uganda Pan Afr Med J 101517926 IM Female Humans Hyperpigmentation diagnosis pathology Middle

2018 The Pan African medical journal

42. WHAT THE MOST PREVALENT SYSTEMIC DISEASES ASSOACIATED WITH ORAL HYPERPIGMENTATION?

WHAT THE MOST PREVALENT SYSTEMIC DISEASES ASSOACIATED WITH ORAL HYPERPIGMENTATION? Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email

2020 PROSPERO

43. Paclitaxel-associated reticulate hyperpigmentation: Report and review of chemotherapy-induced reticulate hyperpigmentation Full Text available with Trip Pro

Paclitaxel-associated reticulate hyperpigmentation: Report and review of chemotherapy-induced reticulate hyperpigmentation Drug-induced reticulate hyperpigmentation is uncommon. Including the patient described in this report, chemotherapy-associated reticulate hyperpigmentation has only been described in ten individuals. This paper describes the features of a woman with recurrent and metastatic breast cancer who developed paclitaxel-induced reticulate hyperpigmentation and reviews (...) the characteristics of other oncology patients who developed reticulate hyperpigmentation from their antineoplastic treatment. A 55-year-old Taiwanese woman who developed reticulate hyperpigmentation on her abdomen, back and extremities after receiving her initial treatment for metastatic breast cancer with paclitaxel is described. The hyperpigmentation became darker with each subsequent administration of paclitaxel. The drug was discontinued after five courses and the pigment faded within two months. PubMed

2016 World journal of clinical cases

44. Minocycline-Induced Hyperpigmentation Mimicking Aortic Dissection. (Abstract)

Minocycline-Induced Hyperpigmentation Mimicking Aortic Dissection. Minocycline-induced hyperpigmentation of tissues has been documented previously, but extensive cardiovascular involvement is rarely described in literature. We report a case of marked cardiovascular hyperpigmentation resulting from approximately 4 years of minocycline exposure. We will highlight how intraoperative differentiation of minocycline-induced hyperpigmentation from more sinister causes of discoloration led

2017 Annals of Thoracic Surgery

45. Treatment of Postinflammatory Hyperpigmentation With a Combination of Glycolic Acid Peels and a Topical Regimen in Dark-Skinned Patients: A Comparative Study. (Abstract)

Treatment of Postinflammatory Hyperpigmentation With a Combination of Glycolic Acid Peels and a Topical Regimen in Dark-Skinned Patients: A Comparative Study. Facial postinflammatory hyperpigmentation (PIH) is challenging to manage in patients with skin of color because of the risk of subsequent treatment-related hyperpigmentation.To evaluate the safety and efficacy of combining glycolic acid (GA) peels with a modified Kligman formula (MKF) containing hydroquinone 2%, tretinoin 0.05 (...) %, and hydrocortisone 1% for the treatment of facial PIH in Indian patients.Thirty Indian patients (Fitzpatrick skin Types III-V) with facial PIH were randomly assigned to 2 groups of 15 each. One group received serial GA peels combined with an intervening topical regimen containing MKF. The other group received MKF alone. Results were evaluated by a clinical investigator at baseline and at the end of 21 weeks (3 weeks after treatment completion) using an objective scoring system, the Hyperpigmentation Area

2017 Dermatologic Surgery Controlled trial quality: uncertain

46. Sun-protective behaviors in patients with cutaneous hyperpigmentation: A cross-sectional study. (Abstract)

Sun-protective behaviors in patients with cutaneous hyperpigmentation: A cross-sectional study. Disorders of hyperpigmentation are seen commonly in clinical practice. Despite numerous studies investigating sun-protective habits among healthy persons, little is known about these behaviors within patient populations with hyperpigmentation disorders.We sought to examine photo-protective behaviors and their associations in individuals with disorders of hyperpigmentation.This cross-sectional study (...) was conducted with 404 adults who complained of cutaneous hyperpigmentation.About 67.5% reported using a product containing sunscreen, and 91% endorsed using one with a sun protection factor of 21 or higher. Among the participants, 48.5% were not sure if their sunscreen provided broad-spectrum protection, and only 7.6% reapplied every 2 hours. The odds of a patient with melasma using sunscreen were 6.7 times the odds of a patient with postinflammatory hyperpigmentation using sunscreen (P < .001). Additional

2017 Journal of American Academy of Dermatology

47. Bleomycin induced hyperpigmentation of skin Full Text available with Trip Pro

Bleomycin induced hyperpigmentation of skin 29519375 2018 11 14 1516-8484 40 1 2018 Jan - Mar Revista brasileira de hematologia e hemoterapia Rev Bras Hematol Hemoter Bleomycin induced hyperpigmentation of skin. 90-91 S1516-8484(17)30123-8 10.1016/j.bjhh.2017.08.005 Mishra Kundan K Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Electronic address: mishrak20@gmail.com. Jandial Aditya A Postgraduate Institute of Medical Education and Research (PGIMER

2017 Hematology, Transfusion and Cell Therapy

48. Hyperpigmentation of hard palate induced by chloroquine therapy Full Text available with Trip Pro

Hyperpigmentation of hard palate induced by chloroquine therapy The antimalarials are one of the most commonly prescribed drugs for conditions such as lupus erythematosus and rheumatoid arthritis, and the side effects, though infrequent, are well known. The antimalarial agent chloroquine diphosphate usually causes pigmentary changes in the oral mucosa characterized by a bluish-grey to black discolorations mainly in the hard palate. Considering only the hard palate hyperpigmentation caused (...) by chloroquine, to the best of our knowledge, only 13 cases have been reported in the English language literature. We described an additional case of palate hyperpigmentation related to the chronic use of chloroquine diphosphate in a 60-year-old Mexican woman. Although the diagnosis is usually made based on medication history and clinical presentation, a biopsy specimen may be helpful to confirm the diagnosis. Clinicians must be aware of these drugs and their adverse effects in order to make the correct

2017 Journal of clinical and experimental dentistry

49. Hyperpigmentation of the hard palate mucosa in a patient with chronic myeloid leukaemia taking imatinib Full Text available with Trip Pro

Hyperpigmentation of the hard palate mucosa in a patient with chronic myeloid leukaemia taking imatinib Imatinib mesylate is an inhibitor of the tyrosine kinase Bcr-Abl and a first-line treatment for Philadelphia chromosome-positive chronic myeloid leukaemia (CML). Dermatological side effects include superficial oedema, pustular eruption, lichenoid reactions, erythroderma, and skin rash. Depigmentation of the skin and/or mucosa is uncommon, and hyperpigmentation is rare.We present the case (...) of a 63-year-old Caucasian male with widespread hyperpigmentation of the hard palate associated with a 9-year history of imatinib therapy to treat CML. He did not complain of any symptoms. Clinical examination did not reveal any abnormal pigmentation of the skin or other region of the oral mucosa. He did not smoke cigarettes or drink alcohol. His medication regimen was a proton pump inhibitor, a beta-blocker, cardioaspirin, atorvastatin, and imatinib 400 mg/day. Histopathologically, melanin

2017 Maxillofacial Plastic and Reconstructive Surgery

50. Skin Hyperpigmentation as the Presenting Symptom of Subacute Combined Degeneration of the Spinal Cord Full Text available with Trip Pro

Skin Hyperpigmentation as the Presenting Symptom of Subacute Combined Degeneration of the Spinal Cord Vitamin B12 deficiency results in hematological, neurological, and rarely dermatological complications. Subacute combined degeneration of the cord is one of the neurological complications, and usually the presenting symptom is paresthesia. Herein, we report a case of a 46-year-old man with subacute combined degeneration presenting with knuckle hyperpigmentation.

2017 Case reports in neurological medicine

51. Levetiracetam-Induced Skin Hyperpigmentation: An Extremely Rare Undesirable Side Effect Full Text available with Trip Pro

Levetiracetam-Induced Skin Hyperpigmentation: An Extremely Rare Undesirable Side Effect Levetiracetam is one of the newer second-generation antiepileptic drugs with multiple mechanisms of action. Cutaneous side effects due to levetiracetam are rarely reported in the literature. In this article, we describe a patient with skin hyperpigmentation due to the treatment with levetiracetam with complete resolution after discontinuation of the medication. In addition, we review the topic (...) and hypothesize the mechanism behind this rare complication. To the best of our knowledge, this is the first report of skin hyperpigmentation as a side effect of levetiracetam in the literature. The prescribing physicians should inform the patients about all potential side effect of levetiracetam including skin hyperpigmentation. Similar to many undiagnosed conditions, increased awareness of their existence is the key to diagnosis. Early recognition and timely cessation of therapy are important to reverse

2017 Journal of epilepsy research

52. Asymptomatic Hyperpigmentation without Preceding Inflammation as a Clinical Feature of Citrus Fruits-Induced Phytophotodermatitis Full Text available with Trip Pro

Asymptomatic Hyperpigmentation without Preceding Inflammation as a Clinical Feature of Citrus Fruits-Induced Phytophotodermatitis Phytophotodermatitis is a condition that occurs by contact with plants containing phototoxic agents such as furocoumarins and psoralens with subsequent ultraviolet exposure. Phytophotodermatitis typically presents as sharply defined erythematous patches with occasional blistering, sometimes accompanied with pain or itching sensation. In some cases, however, sudden (...) appearance of asymptomatic hyperpigmentation can be the only clinical finding of phytophotodermatitis. Here, we present two patients with sudden development of asymptomatic pigmentation on their hand without preceding inflammation by the contact with citrus fruits containing photosensitizers and subsequent exposure to strong sunlight. As like these patients, phytophotodermatitis can present with only pigmentation without noticeable inflammation especially in dark skinned people. In such cases, physician

2017 Annals of dermatology

53. Dermatoscopic evaluation and histopathological correlation of acquired dermal macular hyperpigmentation. (Abstract)

Dermatoscopic evaluation and histopathological correlation of acquired dermal macular hyperpigmentation. Acquired dermal macular hyperpigmentation (ADMH) is a hypernym encompassing Riehl's melanosis, lichen planus pigmentosus, and ashy dermatoses that show significant clinicopathological overlap. We sought to describe the dermatoscopic features of ADMH and correlate them with histopathological findings.This was a prospective observational study performed in two phases. A detailed clinical

2017 International Journal of Dermatology

54. Postinflammatory Hyperpigmentation: Epidemiology, Clinical Presentation, Pathogenesis and Treatment. (Abstract)

Postinflammatory Hyperpigmentation: Epidemiology, Clinical Presentation, Pathogenesis and Treatment. Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis that develops following cutaneous inflammation. Common causes of PIH include intrinsic skin conditions (e.g., acne and eczema) as well as external insults to the skin, such as burn injuries and dermatologic procedures. PIH more commonly occurs in individuals with darker skin, for whom it is often a source of significant

2017 American journal of clinical dermatology

55. Postinflammatory hyperpigmentation: A comprehensive overview: Epidemiology, pathogenesis, clinical presentation, and noninvasive assessment technique. (Abstract)

Postinflammatory hyperpigmentation: A comprehensive overview: Epidemiology, pathogenesis, clinical presentation, and noninvasive assessment technique. Postinflammatory hyperpigmentation (PIH) commonly occurs after various endogenous and exogenous stimuli, especially in dark-skinned individuals. PIH is one of the most common complications of procedures performed using laser and other light sources. The severity of PIH is determined by the inherent skin color, degree and depth of inflammation (...) , degree of dermoepidermal junction disruption, inflammatory conditions, and the stability of melanocytes, leading to epidermal and dermal melanin pigment deposition. The depth of melanin pigment is the key factor to predict prognosis and treatment outcome. Epidermal hyperpigmentation fades more rapidly than dermal hyperpigmentation. Various inflammatory disorders can eventually result in PIH. The evaluation of pigmentation using noninvasive tools helps define the level of pigmentation in the skin

2017 Journal of American Academy of Dermatology

56. Postinflammatory hyperpigmentation: A comprehensive overview: Treatment options and prevention. (Abstract)

Postinflammatory hyperpigmentation: A comprehensive overview: Treatment options and prevention. Postinflammatory hyperpigmentation (PIH) occurs after various dermatoses, exogenous stimuli, and dermatologic procedures. The clinical course of PIH is chronic and unpredictable, although the probability of resolution of epidermal hyperpigmentation is better than those of dermal hyperpigmentation. PIH can be prevented or alleviated. When it does occur, the underlying inflammatory conditions should (...) . The second article in this 2-part continuing medical education series on PIH specifically addresses the evidence that supports medical and procedural treatments of PIH and other forms of acquired hyperpigmentation. It also describes a PIH model and provides an algorithm for clinical practice along with discussion about the prevention of PIH.Copyright © 2017 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

2017 Journal of American Academy of Dermatology

57. New data on hyperpigmentation disorders. Full Text available with Trip Pro

New data on hyperpigmentation disorders. Recently visible light (VL) and vascularization triggered by infrared light (IR) play a role in hyperpigmentation disorders of the skin. The aim of this article is to provide an update on the aetiology of hyperpigmentation disorders and means of prevention against UV, visible (VL) and infrared light (IR). The author conducted a literature review of the most recent data about hyperpigmentation disorders and means of prevention and protection. VL impacts (...) on pigmentation, especially in individuals with phototype III, IV or V and also causes the production of Reactive Oxygen Species (ROS), erythema and DNA damage through ROS production as well as photodermatoses. IR is supposed to be involved in melanogenesis throughout the activation of the endothelin receptor B and the mitogen-activated protein kinase, extracellular signal-regulated kinase (ERK)1/2, and protein (p)38. To protect from hyperpigmentation caused by VL, sunscreens containing iron oxides

2017 Journal of the European Academy of Dermatology and Venereology

58. A novel scale for measurement of acquired dermal macular hyperpigmentation (ADHM) severity. (Abstract)

A novel scale for measurement of acquired dermal macular hyperpigmentation (ADHM) severity. 29283460 2018 06 07 1468-3083 32 6 2018 Jun Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol A novel scale for measurement of acquired dermal macular hyperpigmentation severity. e251-e253 10.1111/jdv.14772 Vinay K K Department of Dermatology, Venereology and Leprology, PGIMER, Chandigarh, 160012, India. Dabas G G Department of Dermatology, Venereology

2017 Journal of the European Academy of Dermatology and Venereology

59. Hyperpigmentation after surgery for a deep dermal burn of the dorsum of the hand: partial-thickness debridement followed by medium split-thickness skin grafting vs full-thickness debridement followed by thick split-thickness skin grafting Full Text available with Trip Pro

Hyperpigmentation after surgery for a deep dermal burn of the dorsum of the hand: partial-thickness debridement followed by medium split-thickness skin grafting vs full-thickness debridement followed by thick split-thickness skin grafting Early excision and skin grafting are commonly used to treat deep dermal burns (DDBs) of the dorsum of the hand. Partial-thickness debridement (PTD) is one of the most commonly used procedures for the excision of burned tissue of the dorsum of the hand (...)  < 0.01). Quantitative skin color analyses in both the RGB and HSB color spaces showed that postoperative grafted skin was significantly darker than the adjacent control area in the PTD group, but not in the FTD group.There is a possibility that FTD followed by a thick STSG is an option that can reduce the risk of hyperpigmentation after surgery for DDB of the dorsum of the hand in Japanese patients. Further investigation is needed to clarify whether the FTD or the thick STSG or both are the factor

2016 Burns & trauma

60. Treatment of oral hyperpigmentation and gummy smile using lasers and role of plasma as a novel treatment technique in dentistry: An introductory review Full Text available with Trip Pro

Treatment of oral hyperpigmentation and gummy smile using lasers and role of plasma as a novel treatment technique in dentistry: An introductory review Gingival hyperpigmentation and the condition known as gummy smile are very common dental cosmetic problems. Gingival hyperpigmentation arises due to the excess presence of melanin in certain regions of the gums. In the case of gummy smile, more than the required amount of gingival tissue is exposed upon smiling. An aesthetically pleasing smile (...) should expose only a negligible amount of gingival tissue. Gummy smile and gingival hyperpigmentation can have detrimental effects on the aesthetic quality of a smile, and thereby a wide variety of treatment options must be taken into consideration depending patient outcome objectives. The use of a laser as a treatment modality is considered to be a promising option for such cases. We aim to explain the effects of using a laser on the gingiva and discuss the advantages and disadvantages of this type

2017 Oncotarget

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>