How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

2,860 results for

Hyperpigmentation

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

201. Long-Pulse Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment Improves Amiodarone-Induced Hyperpigmentation. (Abstract)

Long-Pulse Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment Improves Amiodarone-Induced Hyperpigmentation. 21707831 2012 01 05 2015 11 19 1524-4725 37 10 2011 Oct Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Long-pulse neodymium-doped yttrium aluminum garnet laser treatment improves amiodarone-induced hyperpigmentation. 1539-41 10.1111/j.1524-4725.2011.02083.x Bagheri Sepideh S Department of Dermatology, University (...) of California at Davis, Sacramento, California, USA. dbeisen@ucdavis.edu Eisen Daniel D eng Case Reports Journal Article 2011 06 24 United States Dermatol Surg 9504371 1076-0512 0 Anti-Arrhythmia Agents N3RQ532IUT Amiodarone IM Aged Amiodarone adverse effects Anti-Arrhythmia Agents adverse effects Face Humans Hyperpigmentation chemically induced radiotherapy Lasers, Solid-State therapeutic use Low-Level Light Therapy Male 2011 6 29 6 0 2011 6 29 6 0 2012 1 6 6 0 ppublish 21707831 10.1111/j.1524

2011 Dermatologic Surgery

203. Epidermolysis bullosa

combination of milia, scarring, and dystrophic nails absence of milia, scarring, and dystrophic nails exuberant granulation tissue herpetiform blistering pseudosyndactyly enamel hypoplasia reticulate hyperpigmentation muscular dystrophy tracheolaryngeal stenosis or stricture severe upper airway disease onset in mid or late childhood inverse (intertriginous), acral, or centripetal distribution of skin involvement severe cardiomyopathy Family history of EB Diagnostic investigations immunofluorescence

2019 BMJ Best Practice

204. Compression therapy for treating post-thrombotic syndrome. (Abstract)

Compression therapy for treating post-thrombotic syndrome. Post-thrombotic syndrome (PTS) is a long-term complication of deep vein thrombosis (DVT) characterised by chronic complaints such as oedema and skin changes including; venous ectasia, varicose veins, redness, eczema, hyperpigmentation, and in severe cases fibrosis of the subcutaneous adipose in the affected limb. These chronic complaints are the effects of venous outflow restriction that can cause symptoms such as heaviness, itching

2019 Cochrane

205. High-intensity focused ultrasound for symptomatic breast fibroadenoma

. A first-degree skin burn with hyperpigmentation visible after 6 months was reported in 1 woman of 7, who had more than 1 fibroadenoma, in the case series of 20 women treated by HIFU. 5.4 Hyperpigmentation of the skin was reported in 1 woman within days after the procedure in the case series of 42 women treated by HIFU. Hyperpigmentation of the skin was reported by 30% (6/20) of women treated by HIFU at 3 months and 20% (4/20) at 6 months in the non-randomised controlled study of 40 women. 5.5

2017 National Institute for Health and Clinical Excellence - Interventional Procedures

206. Radiation therapy for early Dupuytren's disease

weeks of follow-up. Erythema was reported in 2% (5/208) of patients in the case series of 135 patients at up to 1 year. 5.13 Weakness (subjective 10–20% reduction in strength) was reported in 3% (2/60) of sites in the case series of 33 patients within a median follow-up of 31 months. 5.14 Reduced nail health was reported in 3% (2/60) of sites in the case series of 33 patients within a median follow-up of 31 months. 5.15 Hyperpigmentation was reported in 3% (2/60) of sites in the case series of 33

2017 National Institute for Health and Clinical Excellence - Interventional Procedures

207. Diagnosis and Management of Acute Pulmonary Embolism Full Text available with Trip Pro

Plasminogen Activator for Occluded Coronary Arteries HAS-BLED Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly (>65 years), Drugs/alcohol concomitantly HERDOO2 Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30 kg/m 2 ; or Older age, ≥65 years H-FABP Heart-type fatty acid-binding protein HIV Human immunodeficiency virus HR Hazard ratio INR International

2019 European Society of Cardiology

208. Monkeypox

with: fever headache muscle aches backache swollen lymph nodes chills exhaustion Within 1 to 5 days after the appearance of fever, a rash develops, often beginning on the face then spreading to other parts of the body. The rash changes and goes through different stages before finally forming a scab which later falls off. Images of individual monkeypox lesions Notes areas of erythema and/or skin hyperpigmentation are often seen around discrete lesions lesions can vary in size and may be larger than those

2019 Public Health England

210. An unusual case of capecitabine hyperpigmentation: Is hyperpigmentation a part of hand-foot syndrome or a separate entity? Full Text available with Trip Pro

An unusual case of capecitabine hyperpigmentation: Is hyperpigmentation a part of hand-foot syndrome or a separate entity? A 59-year-old man with adenocarcinoma of stomach was prescribed capecitabine as adjuvant chemotherapy. After two cycles of therapy, patient developed hyperpigmentation on hands and feet. Examination revealed a peculiar distribution of hyperpigmentation on hands and feet and in addition, hyperpigmented spots on the dorsum of tongue. Although hand-foot syndrome (HFS (...) ) to capecitabine solely manifesting as palmoplantar hyperpigmentation has been described earlier, this is probably the first instance wherein oral pigmentation has also been found in association. In addition, this finding lends support to the growing argument of hyperpigmentation being a separate entity: different from HFS, both therefore being separate adverse effects of the same drug.

2010 Indian journal of pharmacology

211. Refractory extrapulmonary sarcoidosis: infliximab

involving several organs and causing severe symptoms and functional impairment. It is characterised by the presence of non-caseating granulomas (non-necrotising nodules of inflammation and scarring) in the organs. The lungs are affected in more than 90% of people with sarcoidosis (see the evidence summary on pulmonary sarcoidosis for more information). The skin is the second most commonly affected organ. Manifestations include hyperpigmentation, hypopigmentation, keloid reaction, lupus pernio (lesions

2017 National Institute for Health and Clinical Excellence - Advice

212. Adrenal suppression

or orthostatic symptoms myalgia or arthralgia abdominal pain cushingoid examination features hx of difficult-to-control diabetes or hypertension absence of hyperpigmentation or autoimmune stigmata typical features of underlying disease medroxyprogesterone acetate use hx of treatment for endogenous Cushing's syndrome hypotension with or without orthostasis systemic glucocorticoid administration high potency or dose of exogenous glucocorticoids local glucocorticoid administration glucocorticoid treatment >3

2018 BMJ Best Practice

213. Epidermolysis bullosa

combination of milia, scarring, and dystrophic nails absence of milia, scarring, and dystrophic nails exuberant granulation tissue herpetiform blistering pseudosyndactyly enamel hypoplasia reticulate hyperpigmentation muscular dystrophy tracheolaryngeal stenosis or stricture severe upper airway disease onset in mid or late childhood inverse (intertriginous), acral, or centripetal distribution of skin involvement severe cardiomyopathy Family history of EB Diagnostic investigations immunofluorescence

2018 BMJ Best Practice

214. Bullous pemphigoid

or urticarial lesions for weeks or months. In the bullous stage, characteristic, tense vesicles or bullae develop on apparently normal or erythematous skin of the pre-existing eczematous or urticarial eruption. If the blisters burst, the eroded, crusty areas slowly heal to leave post-inflammatory hyperpigmentation. The lesions are usually symmetrical and favour the flexural aspects of the extremities, lower trunk, and abdomen. The treatment goal is to decrease or stop blister formation, to promote healing

2018 BMJ Best Practice

215. Tropical sprue

]. History and exam prolonged exposure to an endemic area constitutional symptoms diarrhoea bloating foul-smelling, greasy stools swollen/sore tongue and lips glossitis numbness of fingers and toes abdominal cramping fever leg swelling hair loss cheilitis/angular stomatitis pedal oedema hyperactive bowel sounds/borborygmi hyperpigmentation/eczematous rash pallor dry eyes corneal xerosis night blindness decreased deep tendon reflexes/decreased vibratory sensation prolonged exposure to an endemic area HLA

2018 BMJ Best Practice

216. Melasma

. This is due to an increase in melanocyte activity and melanin deposition in the skin. Sunlight and hormonal influence are important factors in disease aetiology. Victor FC, Gelber J, Rao B. Melasma: a review. J Cutan Med Surg. 2004 Mar-Apr;8(2):97-102. http://www.ncbi.nlm.nih.gov/pubmed/15685388?tool=bestpractice.com History and exam centrofacial, malar, or mandibular distribution of muddy brown to grey hyperpigmentation female sex Fitzpatrick III to VI skin types UV radiation oral contraceptive pill

2018 BMJ Best Practice

217. Non-diabetic hypoglycaemia

unexplained weight gain unexplained weight loss hyperpigmentation hypotension short stature middle age female gender ethanol consumption bariatric surgery liver failure renal failure intense exercise fibromas sarcomas fibrosarcomas insulinoma adrenal insufficiency growth hormone deficiency hypopituitarism sepsis glycogen storage diseases anorexia nervosa malnutrition exogenous insulin ackee fruit ingestion haloperidol exposure quinine exposure quinolone exposure sulfonylurea exposure disopyramide exposure

2018 BMJ Best Practice

218. Addison's disease

Addison's disease Addison's disease - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Addison's disease Last reviewed: February 2019 Last updated: December 2018 Summary Presentation may be acute or insidious, with substantial fatigue and weakness associated with mucocutaneous hyperpigmentation, hypotension and/or postural hypotension, and salt craving. Adrenocorticotrophic hormone stimulation test is performed (...) in children is not specifically covered in this topic, but should result in referral to a paediatric endocrinology specialist. History and exam presence of risk factors fatigue anorexia weight loss hyperpigmentation salt craving nausea vomiting hypotension arthralgia and myalgia female sex adrenocortical autoantibodies adrenal haemorrhage autoimmune diseases tuberculosis (TB) non-TB bacterial infection fungal infection HIV drugs that inhibit cortisol production metastatic malignancy coeliac disease

2018 BMJ Best Practice

219. Contact dermatitis

lichenoid lesions corrosion or ulceration pustules and acneiform lesions social hx of exposure persistence of symptoms scaling lichenification crusting erythema multiforme cellulitic lesions leukoderma hypopigmentation hyperpigmentation purpura miliaria alopecia granulomatous lesions occupation with frequent exposure to water or caustic material atopic dermatitis Diagnostic investigations patch testing repeated open application test (ROAT) or provocative use test (PUT) skin biopsy reflectance confocal

2018 BMJ Best Practice

220. Overview of dermatitis

clearly delineated with sharp borders. Hyperpigmentation, fissuring, and scaling may also occur. Belsito DV. The diagnostic evaluation, treatment, and prevention of allergic contact dermatitis in the new millennium. J Allergy Clin Immunol. 2000 Mar;105(3):409-20. http://www.ncbi.nlm.nih.gov/pubmed/10719287?tool=bestpractice.com After an allergen or irritant is identified, the main goals of treatment are avoidance of future exposure and resolution of existing dermatitis. ICD is treated with exposure

2018 BMJ Best Practice

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>