How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

2,860 results for

Hyperpigmentation

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Progressive cribriform and zosteriform hyperpigmentation: a clinicopathologic study. (Abstract)

Progressive cribriform and zosteriform hyperpigmentation: a clinicopathologic study. Progressive cribriform and zosteriform hyperpigmentation (PCZH) is a disorder of pigmentation. Although several cases of PCZH have been reported, no clinicopathologic studies of the condition have been published in the English-language literature.The purpose of this study was to determine the clinical characteristics and histologic findings of PCZH.Between 1999 and 2009, 30 patients were diagnosed with PCZH

2012 International Journal of Dermatology

182. Hyperpigmentation and atrophy. (Abstract)

Hyperpigmentation and atrophy. We suspected a malignancy, but a conversation with the patient provided a telling clue.

2012 Journal of Family Practice

183. Leukodystrophy, skin hyperpigmentation, and adrenal atrophy: Siemerling-Creutzfeldt disease. Transmission through several generations in two families. Full Text available with Trip Pro

Leukodystrophy, skin hyperpigmentation, and adrenal atrophy: Siemerling-Creutzfeldt disease. Transmission through several generations in two families. Two apparently unrelated families with a history of leukodystrophy associated with adrenal insufficiency are presented. Only about 20 cases of this syndrome have been reported until now. It was first described by Siemerling and Creutzfeldt; therefore we propose the designation Siemerling-Creutzfeldt disease. Our pedigrees include 15 additional

1975 American Journal of Human Genetics

184. Hyperpigmentation associated with oxprenolol administration. Full Text available with Trip Pro

Hyperpigmentation associated with oxprenolol administration. 871864 1977 09 02 2018 11 13 0007-1447 2 6082 1977 Jul 30 British medical journal Br Med J Hyperpigmentation associated with oxprenolol administration. 296 Harrower A D AD Strong J A JA eng Case Reports Journal Article England Br Med J 0372673 0007-1447 519MXN9YZR Oxprenolol AIM IM Female Humans Middle Aged Oxprenolol adverse effects Pigmentation Disorders chemically induced 1977 7 30 1977 7 30 0 1 1977 7 30 0 0 ppublish 871864

1977 British medical journal

185. Hyperpigmentation of Skin Full Text available with Trip Pro

Hyperpigmentation of Skin 13969176 1998 11 01 2018 12 01 0007-1447 1 5347 1963 Jun 29 British medical journal Br Med J Hyperpigmentation of skin. A sign of vitamin-B12 deficiency. 1713-5 BAKER S J SJ IGNATIUS M M JOHNSON S S VAISH S K SK eng Journal Article England Br Med J 0372673 0007-1447 0 Vitamins OM Humans Hyperpigmentation Pigmentation Disorders Skin Vitamin B 12 Deficiency Vitamins PIGMENTATION DISORDERS VITAMIN B 12 DEFICIENCY 1963 6 29 1963 6 29 0 1 1963 6 29 0 0 ppublish 13969176

1963 British medical journal

186. An unusual case of non-malignant skin hyperpigmentation. Full Text available with Trip Pro

An unusual case of non-malignant skin hyperpigmentation. 534918 1980 05 14 2017 11 17 0007-1447 2 6205 1979 Dec 22-29 British medical journal Br Med J An unusual case of non-malignant skin hyperpigmentation. 1628-9 Potter A R AR eng Case Reports Journal Article England Br Med J 0372673 0007-1447 AIM IM Adult Animals Diagnosis, Differential Humans Insecta Male Melanoma diagnosis Pigmentation Disorders diagnosis etiology Skin Neoplasms diagnosis 1979 12 22 1979 12 22 0 1 1979 12 22 0 0 ppublish

1979 British medical journal

187. Hyperpigmentation

Hyperpigmentation Hyperpigmentation - Dermatologic Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / IN THIS TOPIC OTHER TOPICS IN THIS CHAPTER Test your knowledge Diagnostic Tests for Skin (...) Education NOTE: This is the Professional Version. CONSUMERS: Topic Resources Hyperpigmentation has multiple causes and may be focal or diffuse. Most cases are due to an increase in melanin production and deposition. (See also .) Focal hyperpigmentation is most often postinflammatory in nature, occurring after injury (eg, and ) or other causes of inflammation (eg, , ). Focal linear hyperpigmentation is commonly due to phytophotodermatitis, which is a phototoxic reaction that results from ultraviolet

2013 Merck Manual (19th Edition)

188. Hyperpigmentation in Laugier–Hunziker syndrome Full Text available with Trip Pro

Hyperpigmentation in Laugier–Hunziker syndrome 21825050 2011 12 07 2018 11 13 1488-2329 183 12 2011 Sep 06 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Hyperpigmentation in Laugier-Hunziker syndrome. 1402 10.1503/cmaj.110211 Ma Dong-Lai DL Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. mdonglai@public3.bta.net.cn Vano-Galvan Sergio S eng (...) Case Reports Journal Article 2011 08 08 Canada CMAJ 9711805 0820-3946 AIM IM Female Humans Hyperpigmentation pathology Lip pathology Middle Aged Mouth Mucosa pathology Nail Diseases pathology Syndrome Tongue pathology 2011 8 10 6 0 2011 8 10 6 0 2011 12 13 0 0 ppublish 21825050 cmaj.110211 10.1503/cmaj.110211 PMC3168631 Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003 Sep;96(3):288-92 12973285 Gut. 2010 Jul;59(7):975-86 20581245 Int J Dermatol. 2004 Aug;43(8):571-4 15304179

2011 CMAJ : Canadian Medical Association Journal

189. Hyperpigmentation in human solar lentigo is promoted by heparanase-induced loss of heparan sulfate chains at the dermal-epidermal junction. (Abstract)

Hyperpigmentation in human solar lentigo is promoted by heparanase-induced loss of heparan sulfate chains at the dermal-epidermal junction. Skin pigmentation induced by ultraviolet B radiation is caused in part by inflammation mediated by cytokines secreted from keratinocytes and fibroblasts in the irradiated area. Heparanase is also activated in the irradiated skin, and this leads to loss of heparan sulfate at the dermal-epidermal junction (DEJ), resulting in uncontrolled diffusion of heparan

2011 Journal of dermatological science

190. Postinflammatory hyperpigmentation: etiologic and therapeutic considerations. (Abstract)

Postinflammatory hyperpigmentation: etiologic and therapeutic considerations. Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis and sequela of a variety of inflammatory skin conditions. PIH can have a negative impact on a patient's quality of life, particularly for darker-skinned patients. Studies show that dyschromias, including PIH, are one of the most common presenting complaints of darker-skinned racial ethnic groups when visiting a dermatologist. This is likely due

2011 American journal of clinical dermatology

191. Tegafur-induced acral hyperpigmentation Full Text available with Trip Pro

Tegafur-induced acral hyperpigmentation Tegafur is a prodrug of 5-fluorouracil (5-FU) with a similar spectrum of antitumor activity. It is used in the treatment of advanced gastrointestinal neoplasms. Over 5-FU, tegafur has the advantage of oral administration and less hematologic toxicity. Gastrointestinal toxicity is its main dose-limiting factor. The cutaneous adverse effects of tegafur include mucositis, photosensitivity, diffuse or nail-restricted hyperpigmentation, palmoplantar (...) erythrodysesthesia syndrome, palmoplantar keratoderma, sclerodactyly and Raynaud phenomenon. We report here the case of a patient who developed acral hyperpigmentation during treatment with tegafur.

2011 Dermatology Reports

192. Management of Gingival Hyperpigmentation by Semiconductor Diode Laser Full Text available with Trip Pro

Management of Gingival Hyperpigmentation by Semiconductor Diode Laser Gingival hyperpigmentation is caused by excessive deposition of melanin in the basal and suprabasal cell layers of the epithelium. Although melanin pigmentation of the gingiva is completely benign, cosmetic concerns are common, particularly in patients having a very high smile line (gummy smile). Various depigmentation techniques have been employed, such as scalpel surgery, gingivectomy, gingivectomy with free gingival

2011 Journal of cutaneous and aesthetic surgery

193. Controversies on cosmetic outcomes in black women after breast conservation therapy: hyperperception or hyperpigmentation? Full Text available with Trip Pro

Controversies on cosmetic outcomes in black women after breast conservation therapy: hyperperception or hyperpigmentation? Multiple studies have reported inferior cosmetic outcomes after breast conservation surgery and adjuvant radiation therapy in black women. However, cosmetic analysis scales contemporarily utilized in the field of radiation oncology rely largely on subjective visual and tactile perception. These methods are undeniably fraught with intraobserver and interobserver variability

2011 Clinical, cosmetic and investigational dermatology

194. Long-Term Follow-Up of a Case of Cheek Hyperpigmentation Associated with McCune-Albright Syndrome Treated with Q-Switched Ruby Laser. (Abstract)

Long-Term Follow-Up of a Case of Cheek Hyperpigmentation Associated with McCune-Albright Syndrome Treated with Q-Switched Ruby Laser. 21272121 2011 04 19 2015 11 19 1524-4725 37 2 2011 Feb Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Long-term follow-up of a case of cheek hyperpigmentation associated with McCune-Albright syndrome treated with Q-switched ruby laser. 263-6 10.1111/j.1524-4725.2010.01864.x Ozawa Toshiyuki T (...) Department of Plastic and Reconstructive Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan. Tateishi Chiharu C Shirakawa Makiko M Murakami Emi E Ishii Masamitsu M Harada Teruichi T eng Case Reports Journal Article 2011 01 27 United States Dermatol Surg 9504371 1076-0512 IM Cheek Child Female Fibrous Dysplasia, Polyostotic complications pathology Follow-Up Studies Humans Hyperpigmentation etiology pathology radiotherapy Lasers, Solid-State therapeutic use Low-Level Light Therapy

2011 Dermatologic Surgery

195. Commentary: use of oral therapy for the prevention of postinflammatory hyperpigmentation. (Abstract)

Commentary: use of oral therapy for the prevention of postinflammatory hyperpigmentation. 21518099 2011 07 26 2013 11 21 1524-4725 37 5 2011 May Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Use of oral therapy for the prevention of postinflammatory hyperpigmentation. 611 10.1111/j.1524-4725.2011.01958.x McDaniel David H DH Institute of Anti-Aging Research, Eastern Virginia Medical School, Virginia Beach, Virginia, USA. mail (...) @lsvcv.com eng Comment Journal Article United States Dermatol Surg 9504371 1076-0512 0 Antifibrinolytic Agents 6T84R30KC1 Tranexamic Acid IM Dermatol Surg. 2011 May;37(5):605-10 21457392 Administration, Oral Antifibrinolytic Agents administration & dosage therapeutic use Humans Hyperpigmentation etiology prevention & control Inflammation etiology prevention & control Japan Lasers adverse effects Tranexamic Acid administration & dosage therapeutic use 2011 4 27 6 0 2011 4 27 6 0 2011 7 27 6 0 ppublish

2011 Dermatologic Surgery

196. Non-ablative 1550 nm fractional laser therapy not effective for erythema dyschromicum perstans and postinflammatory hyperpigmentation: a pilot study. (Abstract)

Non-ablative 1550 nm fractional laser therapy not effective for erythema dyschromicum perstans and postinflammatory hyperpigmentation: a pilot study. Erythema dyschromicum perstans and postinflammatory hyperpigmentation (PIH) are characterized by papillary dermal pigmentation or pigment incontinence. To date, no standard treatment is available. Fractional laser therapy (FLT) was recently reported to improve different pigment disorders.To assess the efficacy and safety of non-ablative FLT (...) in the treatment of erythema dyschromicum perstans and PIH.Eight patients with erythema dyschromicum perstans and six patients with PIH were included. In each patient, two similar test regions were randomized to receive either five fractional laser treatments in combination with intermittent daily topical bleaching or the same intermittent regimen of topical bleaching alone. Three months after the last treatment, improvement of hyperpigmentation was assessed by melanin index, reflectance spectroscopy

2011 Journal of Dermatological Treatment Controlled trial quality: uncertain

197. Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study. (Abstract)

Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study. Although there are few differences in the incidence and pathophysiology of acne across various races and ethnicities, there is some evidence that black patients may have larger sebaceous glands and increased sebum production. Of greater clinical relevance, patients with darker skin types are at increased risk for the development of post (...) -inflammatory hyperpigmentation (PIH), which some find as or more troubling than acne itself. This common and bothersome sequelum of acne can be difficult to manage in this population. Topical azelaic acid gel is recognized to have anti-tyrosinase activity, suggesting it may be a suitable treatment option for mild-to-moderate acne with associated moderate-to-severe PIH. This pilot study demonstrates the efficacy of topical AzA gel 15% when applied twice daily for the reduction of both acne and PIH. J

2011 Journal of drugs in dermatology : JDD

198. A prospective randomized controlled study of oral tranexamic acid for preventing postinflammatory hyperpigmentation after Q-switched ruby laser. Full Text available with Trip Pro

A prospective randomized controlled study of oral tranexamic acid for preventing postinflammatory hyperpigmentation after Q-switched ruby laser. Postinflammatory hyperpigmentation (PIH) is the most common skin complication in Asians after invasive cosmetic treatments.To determine whether oral tranexamic acid (TA) reduces the incidence of PIH after Q-switched ruby laser (QSRL) treatment.Thirty-two Japanese women underwent QSRL treatment for senile lentigines on the face. They were randomly

2011 Dermatologic Surgery Controlled trial quality: uncertain

199. Periorbital Hyperpigmentation in Asians: An Epidemiologic Study and a Proposed Classification. (Abstract)

Periorbital Hyperpigmentation in Asians: An Epidemiologic Study and a Proposed Classification. Periorbital hyperpigmentation (POH) presents with a dark area surrounding the eyelids. It is an ill-defined condition, and the pathogenesis can be multifactorial.This epidemiologic study was conducted to assess the prevalence of periorbital hyperpigmentation in Singapore in an attempt to propose a classification.One thousand consecutive patients attending the general dermatology clinic at the National (...) Skin Center were enrolled in the study to assess for POH, of whom 200 with POH were examined and investigated to define the cause of POH. The possible causes were determined according to a detailed history, clinical examination, and assessment by three dermatologists. The extent of the POH was measured using a mexameter.The commonest form of POH was the vascular type (41.8%), followed by constitutional (38.6%), postinflammatory hyperpigmentation (12%), and shadow effects (11.4%). The vascular type

2011 Dermatologic Surgery

200. Approach to reticulate hyperpigmentation. (Abstract)

Approach to reticulate hyperpigmentation. Reticulate hyperpigmentation is a feature of a number of conditions, which differ in age of onset and distribution of the lesions. Associated clinical findings (e.g. hair, nail, teeth, systemic involvement), are used to differentiate between the conditions. Histopathological examination is useful in some disorders. Diagnosing the disorders is important, because the underlying causes may be treatable, and some of the disorders are associated (...) with malignancies and life-threatening systemic involvement. In this review, I present a concise, systematic approach to the treatment of the patient with reticulate hyperpigmentation.© The Author(s). CED © 2011 British Association of Dermatologists.

2011 Clinical & Experimental Dermatology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>