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Hyperpigmentation

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181. Commentary: use of oral therapy for the prevention of postinflammatory hyperpigmentation. (PubMed)

Commentary: use of oral therapy for the prevention of postinflammatory hyperpigmentation. 21518099 2011 07 26 2013 11 21 1524-4725 37 5 2011 May Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Use of oral therapy for the prevention of postinflammatory hyperpigmentation. 611 10.1111/j.1524-4725.2011.01958.x McDaniel David H DH Institute of Anti-Aging Research, Eastern Virginia Medical School, Virginia Beach, Virginia, USA. mail (...) @lsvcv.com eng Comment Journal Article United States Dermatol Surg 9504371 1076-0512 0 Antifibrinolytic Agents 6T84R30KC1 Tranexamic Acid IM Dermatol Surg. 2011 May;37(5):605-10 21457392 Administration, Oral Antifibrinolytic Agents administration & dosage therapeutic use Humans Hyperpigmentation etiology prevention & control Inflammation etiology prevention & control Japan Lasers adverse effects Tranexamic Acid administration & dosage therapeutic use 2011 4 27 6 0 2011 4 27 6 0 2011 7 27 6 0 ppublish

2011 Dermatologic Surgery

182. Periorbital Hyperpigmentation in Asians: An Epidemiologic Study and a Proposed Classification. (PubMed)

Periorbital Hyperpigmentation in Asians: An Epidemiologic Study and a Proposed Classification. Periorbital hyperpigmentation (POH) presents with a dark area surrounding the eyelids. It is an ill-defined condition, and the pathogenesis can be multifactorial.This epidemiologic study was conducted to assess the prevalence of periorbital hyperpigmentation in Singapore in an attempt to propose a classification.One thousand consecutive patients attending the general dermatology clinic at the National (...) Skin Center were enrolled in the study to assess for POH, of whom 200 with POH were examined and investigated to define the cause of POH. The possible causes were determined according to a detailed history, clinical examination, and assessment by three dermatologists. The extent of the POH was measured using a mexameter.The commonest form of POH was the vascular type (41.8%), followed by constitutional (38.6%), postinflammatory hyperpigmentation (12%), and shadow effects (11.4%). The vascular type

2011 Dermatologic Surgery

183. Long-Term Follow-Up of a Case of Cheek Hyperpigmentation Associated with McCune-Albright Syndrome Treated with Q-Switched Ruby Laser. (PubMed)

Long-Term Follow-Up of a Case of Cheek Hyperpigmentation Associated with McCune-Albright Syndrome Treated with Q-Switched Ruby Laser. 21272121 2011 04 19 2015 11 19 1524-4725 37 2 2011 Feb Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Long-term follow-up of a case of cheek hyperpigmentation associated with McCune-Albright syndrome treated with Q-switched ruby laser. 263-6 10.1111/j.1524-4725.2010.01864.x Ozawa Toshiyuki T (...) Department of Plastic and Reconstructive Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan. Tateishi Chiharu C Shirakawa Makiko M Murakami Emi E Ishii Masamitsu M Harada Teruichi T eng Case Reports Journal Article 2011 01 27 United States Dermatol Surg 9504371 1076-0512 IM Cheek Child Female Fibrous Dysplasia, Polyostotic complications pathology Follow-Up Studies Humans Hyperpigmentation etiology pathology radiotherapy Lasers, Solid-State therapeutic use Low-Level Light Therapy

2011 Dermatologic Surgery

184. Hyperpigmentation in human solar lentigo is promoted by heparanase-induced loss of heparan sulfate chains at the dermal-epidermal junction. (PubMed)

Hyperpigmentation in human solar lentigo is promoted by heparanase-induced loss of heparan sulfate chains at the dermal-epidermal junction. Skin pigmentation induced by ultraviolet B radiation is caused in part by inflammation mediated by cytokines secreted from keratinocytes and fibroblasts in the irradiated area. Heparanase is also activated in the irradiated skin, and this leads to loss of heparan sulfate at the dermal-epidermal junction (DEJ), resulting in uncontrolled diffusion of heparan

2011 Journal of dermatological science

185. Postinflammatory hyperpigmentation: etiologic and therapeutic considerations. (PubMed)

Postinflammatory hyperpigmentation: etiologic and therapeutic considerations. Postinflammatory hyperpigmentation (PIH) is a reactive hypermelanosis and sequela of a variety of inflammatory skin conditions. PIH can have a negative impact on a patient's quality of life, particularly for darker-skinned patients. Studies show that dyschromias, including PIH, are one of the most common presenting complaints of darker-skinned racial ethnic groups when visiting a dermatologist. This is likely due

2011 American journal of clinical dermatology

186. Hyperpigmentation in Laugier–Hunziker syndrome (PubMed)

Hyperpigmentation in Laugier–Hunziker syndrome 21825050 2011 12 07 2018 11 13 1488-2329 183 12 2011 Sep 06 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Hyperpigmentation in Laugier-Hunziker syndrome. 1402 10.1503/cmaj.110211 Ma Dong-Lai DL Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. mdonglai@public3.bta.net.cn Vano-Galvan Sergio S eng (...) Case Reports Journal Article 2011 08 08 Canada CMAJ 9711805 0820-3946 AIM IM Female Humans Hyperpigmentation pathology Lip pathology Middle Aged Mouth Mucosa pathology Nail Diseases pathology Syndrome Tongue pathology 2011 8 10 6 0 2011 8 10 6 0 2011 12 13 0 0 ppublish 21825050 cmaj.110211 10.1503/cmaj.110211 PMC3168631 Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003 Sep;96(3):288-92 12973285 Gut. 2010 Jul;59(7):975-86 20581245 Int J Dermatol. 2004 Aug;43(8):571-4 15304179

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2011 CMAJ : Canadian Medical Association Journal

187. Tegafur-induced acral hyperpigmentation (PubMed)

Tegafur-induced acral hyperpigmentation Tegafur is a prodrug of 5-fluorouracil (5-FU) with a similar spectrum of antitumor activity. It is used in the treatment of advanced gastrointestinal neoplasms. Over 5-FU, tegafur has the advantage of oral administration and less hematologic toxicity. Gastrointestinal toxicity is its main dose-limiting factor. The cutaneous adverse effects of tegafur include mucositis, photosensitivity, diffuse or nail-restricted hyperpigmentation, palmoplantar (...) erythrodysesthesia syndrome, palmoplantar keratoderma, sclerodactyly and Raynaud phenomenon. We report here the case of a patient who developed acral hyperpigmentation during treatment with tegafur.

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2011 Dermatology Reports

188. Long-Pulse Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment Improves Amiodarone-Induced Hyperpigmentation. (PubMed)

Long-Pulse Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment Improves Amiodarone-Induced Hyperpigmentation. 21707831 2012 01 05 2015 11 19 1524-4725 37 10 2011 Oct Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Long-pulse neodymium-doped yttrium aluminum garnet laser treatment improves amiodarone-induced hyperpigmentation. 1539-41 10.1111/j.1524-4725.2011.02083.x Bagheri Sepideh S Department of Dermatology, University (...) of California at Davis, Sacramento, California, USA. dbeisen@ucdavis.edu Eisen Daniel D eng Case Reports Journal Article 2011 06 24 United States Dermatol Surg 9504371 1076-0512 0 Anti-Arrhythmia Agents N3RQ532IUT Amiodarone IM Aged Amiodarone adverse effects Anti-Arrhythmia Agents adverse effects Face Humans Hyperpigmentation chemically induced radiotherapy Lasers, Solid-State therapeutic use Low-Level Light Therapy Male 2011 6 29 6 0 2011 6 29 6 0 2012 1 6 6 0 ppublish 21707831 10.1111/j.1524

2011 Dermatologic Surgery

189. Approach to reticulate hyperpigmentation. (PubMed)

Approach to reticulate hyperpigmentation. Reticulate hyperpigmentation is a feature of a number of conditions, which differ in age of onset and distribution of the lesions. Associated clinical findings (e.g. hair, nail, teeth, systemic involvement), are used to differentiate between the conditions. Histopathological examination is useful in some disorders. Diagnosing the disorders is important, because the underlying causes may be treatable, and some of the disorders are associated (...) with malignancies and life-threatening systemic involvement. In this review, I present a concise, systematic approach to the treatment of the patient with reticulate hyperpigmentation.© The Author(s). CED © 2011 British Association of Dermatologists.

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2011 Clinical & Experimental Dermatology

190. A prospective randomized controlled study of oral tranexamic acid for preventing postinflammatory hyperpigmentation after Q-switched ruby laser. (PubMed)

A prospective randomized controlled study of oral tranexamic acid for preventing postinflammatory hyperpigmentation after Q-switched ruby laser. Postinflammatory hyperpigmentation (PIH) is the most common skin complication in Asians after invasive cosmetic treatments.To determine whether oral tranexamic acid (TA) reduces the incidence of PIH after Q-switched ruby laser (QSRL) treatment.Thirty-two Japanese women underwent QSRL treatment for senile lentigines on the face. They were randomly

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2011 Dermatologic Surgery Controlled trial quality: uncertain

191. Non-ablative 1550 nm fractional laser therapy not effective for erythema dyschromicum perstans and postinflammatory hyperpigmentation: a pilot study. (PubMed)

Non-ablative 1550 nm fractional laser therapy not effective for erythema dyschromicum perstans and postinflammatory hyperpigmentation: a pilot study. Erythema dyschromicum perstans and postinflammatory hyperpigmentation (PIH) are characterized by papillary dermal pigmentation or pigment incontinence. To date, no standard treatment is available. Fractional laser therapy (FLT) was recently reported to improve different pigment disorders.To assess the efficacy and safety of non-ablative FLT (...) in the treatment of erythema dyschromicum perstans and PIH.Eight patients with erythema dyschromicum perstans and six patients with PIH were included. In each patient, two similar test regions were randomized to receive either five fractional laser treatments in combination with intermittent daily topical bleaching or the same intermittent regimen of topical bleaching alone. Three months after the last treatment, improvement of hyperpigmentation was assessed by melanin index, reflectance spectroscopy

2011 Journal of Dermatological Treatment Controlled trial quality: uncertain

192. Leukodystrophy, skin hyperpigmentation, and adrenal atrophy: Siemerling-Creutzfeldt disease. Transmission through several generations in two families. (PubMed)

Leukodystrophy, skin hyperpigmentation, and adrenal atrophy: Siemerling-Creutzfeldt disease. Transmission through several generations in two families. Two apparently unrelated families with a history of leukodystrophy associated with adrenal insufficiency are presented. Only about 20 cases of this syndrome have been reported until now. It was first described by Siemerling and Creutzfeldt; therefore we propose the designation Siemerling-Creutzfeldt disease. Our pedigrees include 15 additional

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1975 American Journal of Human Genetics

193. Hyperpigmentation associated with oxprenolol administration. (PubMed)

Hyperpigmentation associated with oxprenolol administration. 871864 1977 09 02 2018 11 13 0007-1447 2 6082 1977 Jul 30 British medical journal Br Med J Hyperpigmentation associated with oxprenolol administration. 296 Harrower A D AD Strong J A JA eng Case Reports Journal Article England Br Med J 0372673 0007-1447 519MXN9YZR Oxprenolol AIM IM Female Humans Middle Aged Oxprenolol adverse effects Pigmentation Disorders chemically induced 1977 7 30 1977 7 30 0 1 1977 7 30 0 0 ppublish 871864

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1977 British medical journal

194. Hyperpigmentation of Skin (PubMed)

Hyperpigmentation of Skin 13969176 1998 11 01 2018 12 01 0007-1447 1 5347 1963 Jun 29 British medical journal Br Med J Hyperpigmentation of skin. A sign of vitamin-B12 deficiency. 1713-5 BAKER S J SJ IGNATIUS M M JOHNSON S S VAISH S K SK eng Journal Article England Br Med J 0372673 0007-1447 0 Vitamins OM Humans Hyperpigmentation Pigmentation Disorders Skin Vitamin B 12 Deficiency Vitamins PIGMENTATION DISORDERS VITAMIN B 12 DEFICIENCY 1963 6 29 1963 6 29 0 1 1963 6 29 0 0 ppublish 13969176

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1963 British medical journal

195. An unusual case of non-malignant skin hyperpigmentation. (PubMed)

An unusual case of non-malignant skin hyperpigmentation. 534918 1980 05 14 2017 11 17 0007-1447 2 6205 1979 Dec 22-29 British medical journal Br Med J An unusual case of non-malignant skin hyperpigmentation. 1628-9 Potter A R AR eng Case Reports Journal Article England Br Med J 0372673 0007-1447 AIM IM Adult Animals Diagnosis, Differential Humans Insecta Male Melanoma diagnosis Pigmentation Disorders diagnosis etiology Skin Neoplasms diagnosis 1979 12 22 1979 12 22 0 1 1979 12 22 0 0 ppublish

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1979 British medical journal

196. Hyperpigmentation

Hyperpigmentation Hyperpigmentation - Dermatologic Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / IN THIS TOPIC OTHER TOPICS IN THIS CHAPTER Test your knowledge Diagnostic Tests for Skin (...) Education NOTE: This is the Professional Version. CONSUMERS: Topic Resources Hyperpigmentation has multiple causes and may be focal or diffuse. Most cases are due to an increase in melanin production and deposition. (See also .) Focal hyperpigmentation is most often postinflammatory in nature, occurring after injury (eg, and ) or other causes of inflammation (eg, , ). Focal linear hyperpigmentation is commonly due to phytophotodermatitis, which is a phototoxic reaction that results from ultraviolet

2013 Merck Manual (19th Edition)

197. An unusual case of capecitabine hyperpigmentation: Is hyperpigmentation a part of hand-foot syndrome or a separate entity? (PubMed)

An unusual case of capecitabine hyperpigmentation: Is hyperpigmentation a part of hand-foot syndrome or a separate entity? A 59-year-old man with adenocarcinoma of stomach was prescribed capecitabine as adjuvant chemotherapy. After two cycles of therapy, patient developed hyperpigmentation on hands and feet. Examination revealed a peculiar distribution of hyperpigmentation on hands and feet and in addition, hyperpigmented spots on the dorsum of tongue. Although hand-foot syndrome (HFS (...) ) to capecitabine solely manifesting as palmoplantar hyperpigmentation has been described earlier, this is probably the first instance wherein oral pigmentation has also been found in association. In addition, this finding lends support to the growing argument of hyperpigmentation being a separate entity: different from HFS, both therefore being separate adverse effects of the same drug.

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2010 Indian journal of pharmacology

198. Treatment of Facial Postinflammatory Hyperpigmentation with Facial Acne in Asian Patients Using a Novel Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser. (PubMed)

Treatment of Facial Postinflammatory Hyperpigmentation with Facial Acne in Asian Patients Using a Novel Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser. 20629692 2011 03 30 2011 02 14 1524-4725 36 9 2010 Sep Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Commentary: treatment of facial postinflammatory hyperpigmentation with facial acne in Asian patients using a novel Q-switched neodymium-doped yttrium aluminum garnet (...) laser. 1381 10.1111/j.1524-4725.2010.01644.x Metelitsa Andrei I AI SkinCare Physicians, Chestnut Hill, Massachusetts, USA. eng Comment Journal Article 2010 07 09 United States Dermatol Surg 9504371 1076-0512 IM Dermatol Surg. 2010 Sep;36(9):1374-80 20629693 Acne Vulgaris complications surgery Dermatitis etiology Face Humans Hyperpigmentation etiology surgery Lasers, Solid-State therapeutic use Skin Diseases etiology surgery 2010 7 16 6 0 2010 7 16 6 0 2011 3 31 6 0 ppublish 20629692 DSU1644 10.1111

2010 Dermatologic Surgery

199. Treatment of Facial Postinflammatory Hyperpigmentation with Facial Acne in Asian Patients Using a Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser. (PubMed)

Treatment of Facial Postinflammatory Hyperpigmentation with Facial Acne in Asian Patients Using a Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser. Postinflammatory hyperpigmentation (PIH) due to facial acne commonly occurs in Fitzpatrick skin types IV to VI and can have a considerable effect on quality of life. The sequelae in terms of pigmentation are often the main reason for consulting a dermatologist and take precedence over the acne itself.The purpose of this study was to evaluate

2010 Dermatologic Surgery

200. Application of a combined sulphorhodamine B and melanin assay to the evaluation of Chinese medicines and their constituent compounds for hyperpigmentation treatment. (PubMed)

Application of a combined sulphorhodamine B and melanin assay to the evaluation of Chinese medicines and their constituent compounds for hyperpigmentation treatment. To investigate the efficacy of traditional Chinese medicine (TCM) in the treatment of hyperpigmentation problems, extracts of herbs selected based on traditional Chinese medical literature were screened.Forty extracts were extracted from 10 selected herbs using hexane, dichloromethane, methanol and water. They were then screened

2010 Journal of Ethnopharmacology

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