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Human Papilloma Virus Vaccine

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61. HPV Vaccination in Men: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines

, HPV vaccine, Human papilloma virus, Human papillomavirus, Men, Boys, male, males Files Rapid Response Summary with Critical Appraisal Published : March 24, 2017 Related Content Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter: (...) are immunocompromised and those with HIV. Additional evidence reviewed for this report has suggested there may be benefits to immunizing men over age 26, particularly high risk populations such as men who have sex with men, although more research is needed in this area. Economic analyses are generally favourable although are dependent on factors such as cost to purchase and administer the vaccine, and dosage schedules. Tags cancer, infectious diseases, vaccines, papillomavirus infections, papillomavirus vaccines

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

62. Knowledge, attitudes and beliefs about vaccination in primary healthcare workers involved in the administration of systematic childhood vaccines, Barcelona, 2016/17. Full Text available with Trip Pro

bivariate and multivariate analysis.ResultsCompleted surveys were returned by 277 (81%) of 342 eligible participants. A quarter of the respondents reported doubts about at least one vaccine in the recommended childhood vaccination calendar. Those with vaccine doubts chose the response option 'vaccine-hesitant' for every single key vaccine belief, knowledge and social norm. Specific vaccine knowledge was lacking in up to 40% of respondents and responses regarding the human papilloma virus vaccine were (...) /17, surveys were administered in person to every public primary care centre (PCC) with a paediatrics department (n = 41). Paediatricians and paediatric nurses responded to questions about disease susceptibility, severity, vaccine effectiveness, vaccine safety, confidence in organisations, key immunisation beliefs, and how they vaccinate or would vaccinate their own children. We used standard descriptive analysis to examine the distribution of key outcome and predictor variables and performed

2019 Euro Surveillance

63. "Saving lives": Adapting and adopting Human Papilloma Virus (HPV) vaccination in Austria. Full Text available with Trip Pro

"Saving lives": Adapting and adopting Human Papilloma Virus (HPV) vaccination in Austria. Vaccination against the sexually transmitted Human Papilloma Virus (HPV), a necessary agent for the development of cervical cancer, has triggered much debate. In Austria, HPV policy turned from "lagging behind" in 2008 into "Europe's frontrunner" by 2013. Drawing on qualitative research, the article shows how the vaccine was transformed and made "good enough" over the course of five years. By means (...) of tinkering and shifting storylines, policy officials and experts disassociated the vaccine from gender, vaccine manufacturers, and youth sexuality. Ultimately, the HPV vaccine functioned to strengthen the national immunization program. To this end, preventing an effective problematization of the extant screening program was essential. Copyright © 2016 The Author. Published by Elsevier Ltd.. All rights reserved.

2016 Social Science & Medicine

64. Is human papilloma virus vaccination effective for oral cancer? Full Text available with Trip Pro

Is human papilloma virus vaccination effective for oral cancer? 27847730 2017 08 16 2234-7550 42 5 2016 Oct Journal of the Korean Association of Oral and Maxillofacial Surgeons J Korean Assoc Oral Maxillofac Surg Is human papilloma virus vaccination effective for oral cancer? 241-242 Kim Young-Kyun YK 0000-0002-7268-3870 Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea. eng Editorial 2016 10 25 Korea (South) J Korean

2016 Journal of the Korean Association of Oral and Maxillofacial Surgeons

65. Two Cases of Acute Disseminated Encephalomyelitis Following Vaccination Against Human Papilloma Virus Full Text available with Trip Pro

Two Cases of Acute Disseminated Encephalomyelitis Following Vaccination Against Human Papilloma Virus We herein present two cases of acute disseminated encephalomyelitis (ADEM) following vaccination against human papilloma virus (HPV). Case 1 experienced diplopia and developed an unstable gait 14 days after a second vaccination of Cervarix. Brain magnetic resonance imaging (MRI) showed an isolated small, demyelinating lesion in the pontine tegmentum. Case 2 experienced a fever and limb (...) dysesthesia 16 days after a second vaccination of Gardasil. Brain MRI revealed hyperintense lesion in the pons with slight edema on a T2-weighted image. Both cases resolved completely. It is important to accumulate further data on confirmed cases of ADEM temporally associated with HPV vaccination.

2016 Internal Medicine

66. Murine hypothalamic destruction with vascular cell apoptosis subsequent to combined administration of human papilloma virus vaccine and pertussis toxin Full Text available with Trip Pro

Murine hypothalamic destruction with vascular cell apoptosis subsequent to combined administration of human papilloma virus vaccine and pertussis toxin Vaccination is the most powerful way to prevent human beings from contracting infectious diseases including viruses. In the case of the human papillomavirus (HPV) vaccine, an unexpectedly novel disease entity, HPV vaccination associated neuro-immunopathetic syndrome (HANS), has been reported and remains to be carefully verified. To elucidate (...) the mechanism of HANS, we applied a strategy similar to the active experimental autoimmune encephalitis (EAE) model - one of the most popular animal models used to induce maximum immunological change in the central nervous system. Surprisingly, mice vaccinated with pertussis toxin showed neurological phenotypes that include low responsiveness of the tail reflex and locomotive mobility. Pathological analyses revealed the damage to the hypothalamus and circumventricular regions around the third ventricle

2016 Scientific reports

67. A physician's reflection on the moral use of human papilloma virus vaccine Full Text available with Trip Pro

A physician's reflection on the moral use of human papilloma virus vaccine Controversies often surround the use of vaccines, particularly among the pediatric population. Often, the possible temporal relationship between vaccination and subsequent disease is at the center of the controversy. However, others have questioned the moral status of the human papilloma virus (HPV) vaccine because of some instances of state coercion and also the possibility that the vaccine may promote promiscuity (...) . This article addresses the moral status of the HPV vaccine from the perspective of a primary care physician and father of four daughters. Lay Summary: Parents are often asked by pediatricians for permission to vaccinate their children under the age of consent against the sexually transmitted virus HPV. This article addresses the medical and moral concerns about vaccination with some guiding principles to assist in a final decision.

2016 The Linacre Quarterly

68. Using Behavioral Risk Factor Data as a surveillance tool to monitor the prevalence of initiation, continuation and completion of Human Papilloma Virus vaccination in children Full Text available with Trip Pro

Using Behavioral Risk Factor Data as a surveillance tool to monitor the prevalence of initiation, continuation and completion of Human Papilloma Virus vaccination in children The Human Papilloma Virus ("HPV") is a common sexually transmitted disease that has infected approximately 79 million men and women in the United States alone. A vaccination is available but in order to be effective it must be received prior to becoming sexually active and recipients must complete a three-dose sequence (...) . In this article we explore the predisposing, enabling and need-based factors associated with parents' or guardians' decision to have their child initiate, continue and complete the Human Papilloma Virus (HPV) vaccine. The data file includes 5531 parents and guardians with presumptive knowledge regarding the number of HPV vaccination their child received. Data includes information on the child (e.g. child׳s age) as well as the adult respondent (e.g. health insurance status). A smaller subset of the dataset

2016 Data in brief

69. Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts

, however unique problems posed by large or extensive genital warts are not so easily solved and treatment of affected patients remains very challenging. Recurrences are common especially among immune-compromised women. This study will test whether giving the quadrivalent human papilloma virus (HPV) vaccine to women with extensive genital warts prior to surgical treatment will improve outcomes. Investigators hypothesize that pre-treatment with HPV vaccine can play a role in the control of both malignant (...) Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2016 Clinical Trials

70. Safety and Immunogenicity Study of Human Papilloma Virus Vaccine in Women Aged 9 to 30 and Men Aged 9 to 17

District Centre for Disease Control and Prevention. Recruitment status was: Not yet recruiting First Posted : September 5, 2016 Last Update Posted : September 5, 2016 Sponsor: Beijing Chaoyang District Centre for Disease Control and Prevention Information provided by (Responsible Party): Beijing Chaoyang District Centre for Disease Control and Prevention Study Details Study Description Go to Brief Summary: This study evaluates the safety of Tetravalent recombinant human papilloma virus vaccine (...) or disease Intervention/treatment Phase Cervical Cancer Biological: Tetravalent recombinant human papilloma virus vaccine (6,11,16,18 type) (Hansenula polymorpha) Biological: placebo Phase 1 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 135 participants Allocation: Randomized Intervention Model: Single Group Assignment Masking: Double (Participant, Investigator) Primary Purpose: Prevention Official Title: Random, Double Blind

2016 Clinical Trials

71. Recombinant Human Papillomavirus Nonavalent Vaccine in Preventing Human Papilloma Virus in Younger Healthy Participants

Recombinant Human Papillomavirus Nonavalent Vaccine in Preventing Human Papilloma Virus in Younger Healthy Participants Recombinant Human Papillomavirus Nonavalent Vaccine in Preventing Human Papilloma Virus in Younger Healthy Participants - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Recombinant Human Papillomavirus Nonavalent Vaccine in Preventing Human Papilloma Virus in Younger Healthy Participants The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02568566 Recruitment Status : Active

2015 Clinical Trials

72. Prevalence of high-risk human papilloma virus in women with high-grade squamous cell intraepithelial lesions in Botswana using Abbott RealTime HPV assay. Full Text available with Trip Pro

Prevalence of high-risk human papilloma virus in women with high-grade squamous cell intraepithelial lesions in Botswana using Abbott RealTime HPV assay. High-risk human papillomavirus (HR-HPV) has been demonstrated to be the necessary cause of cervical carcinoma. High-risk HPV detection has a prognostic significance for the women who are at increased risk of disease progression. HPV genotyping in cervical cancer precursor lesions is crucial for prevention and management of cervical cancer (...) in carcinoma, while HPV 16 was more prevalent in carcinomas than other HR-HPV genotypes.In this study, HPV 16 and other HR-HPV genotypes were commonly associated with HSIL but HPV 18 was uncommon among Botswana women. Our data highlights the need for multivalent HPV vaccines with cross coverage for other high risk HPV other than HPV 16 and 18.

2019 PLoS ONE

73. Oncogenic Viruses and Breast Cancer: Mouse Mammary Tumor Virus (MMTV), Bovine Leukemia Virus (BLV), Human Papilloma Virus (HPV), and Epstein–Barr Virus (EBV) Full Text available with Trip Pro

Oncogenic Viruses and Breast Cancer: Mouse Mammary Tumor Virus (MMTV), Bovine Leukemia Virus (BLV), Human Papilloma Virus (HPV), and Epstein–Barr Virus (EBV) Although the risk factors for breast cancer are well established, namely female gender, early menarche and late menopause plus the protective influence of early pregnancy, the underlying causes of breast cancer remain unknown. The development of substantial recent evidence indicates that a handful of viruses may have a role in breast (...) cancer. These viruses are mouse mammary tumor virus (MMTV), bovine leukemia virus (BLV), human papilloma viruses (HPVs), and Epstein-Barr virus (EBV-also known as human herpes virus type 4). Each of these viruses has documented oncogenic potential. The aim of this review is to inform the scientific and general community about this recent evidence.MMTV and human breast cancer-the evidence is detailed and comprehensive but cannot be regarded as conclusive. BLV and human breast cancer-the evidence

2018 Frontiers in oncology

74. Multi-Year Effect of Human Papillomavirus Vaccination on Recurrent Respiratory Papillomatosis. (Abstract)

Multi-Year Effect of Human Papillomavirus Vaccination on Recurrent Respiratory Papillomatosis. To examine whether human papilloma virus (HPV) vaccination in combination with surgical resection could suppress recurrence for an extended period of time in patients with recurrent respiratory papillomatosis (RRP).In a prospective case series, data of patients who received combination therapy comprising surgery and quadrivalent HPV vaccination (Gardasil; Merck & Co., West Point, PA) were collected (...) . Patients were followed up for RRP from March 2012 to July 2018 in an academic tertiary care center. The patients comprised 16 adults with RRP who were observed for >12 months after HPV vaccination, and whose HPV-DNA status was tested before and for >12 months after completion of combination therapy. The outcomes of this study were the severity score of larynx disease, tumor incidence rate, and relationship between this rate and HPV-DNA negative conversion after therapy.The severity score of laryngeal

2019 Laryngoscope

75. A link between human papilloma virus vaccination and primary ovarian insufficiency: current analysis. (Abstract)

A link between human papilloma virus vaccination and primary ovarian insufficiency: current analysis. The cause of primary ovarian insufficiency (POI) is multifactorial. Known causes include external factors such as chemotherapy, radiotherapy, exposure to endocrine-disrupting chemicals, infections that lead to a permanent insult to the ovary, autoimmune conditions, and genetic causes. An association between the quadrivalent antihuman papilloma vaccine (HPV4) and POI was recently suggested.An (...) increasing number of cases of POI post-HPV4 are being reported. Possible mechanisms for the suspected effect of HPV on female reproductive function are a toxic effect or an autoimmune response. The trigger could be the vaccine immunogen contents or the adjuvants, the latter are used to increase the immune reaction. The adjuvant in HPV4 contains aluminum. Animal models have shown aluminum exposure to inhibit expression of female reproductive hormones and to induce histologic changes in the ovaries

2015 Current Opinion in Obstetrics and Gynecology

76. High-sensitivity human papilloma virus genotyping reveals near universal positivity in anal squamous cell carcinoma: different implications for vaccine prevention and prognosis. (Abstract)

High-sensitivity human papilloma virus genotyping reveals near universal positivity in anal squamous cell carcinoma: different implications for vaccine prevention and prognosis. Characterisation of human papilloma virus (HPV) infection in anal squamous cell carcinoma (ASCC) may have dual importance: first, aetiological; second, prognostic, informing outcome after chemo-radiotherapy (CRT). We undertook HPV genotyping, and allelic characterisations, to evaluate the aetiological role of HPV while (...) for RFS (p < 0.0001) and OS (p = 0.002).In ASCC, near-universal HPV detection rates were demonstrated, higher than generally reported in the literature, and supporting the development of multivalent HPV vaccinations for prevention. By contrast, p16 negatively, but not HPV 16 genotype, is an independent adverse prognosticator after chemo-radiotherapy in patients with ASCC.Copyright © 2015. Published by Elsevier Ltd.

2015 European Journal of Cancer

77. Perceptions of Nigerian Women about Human Papilloma Virus, Cervical Cancer, and HPV Vaccine Full Text available with Trip Pro

Perceptions of Nigerian Women about Human Papilloma Virus, Cervical Cancer, and HPV Vaccine Background. Cervical cancer caused by human papilloma virus (HPV) though preventable has claimed the lives of many women worldwide. This study was embarked upon to evaluate the general knowledge and perceptions of Nigerian women on HPV, cervical cancer, and HPV vaccine. Methods. Structured questionnaires were administered to a cross section of 737 women randomly selected from the general population (...) in two southwestern States of Nigeria. Statistical analysis was done using SPSS computer software version 16. A P value >0.05 was considered statistically significant. Results. One hundred and seventy-six (23.9%) of the respondents had knowledge of HPV; 474 (64.3%) are aware of cervical cancer but only 136 (18.5%) know that HPV causes cervical cancer. 200 (27.1%) are aware that there is an HPV vaccine while 300 (40.7%) had knowledge of Pap smear test. Two hundred and sixty (35.3%) of the respondents

2015 Scientifica

78. Effective nonvaccine interventions to be considered alongside human papilloma virus vaccine delivery. (Abstract)

Effective nonvaccine interventions to be considered alongside human papilloma virus vaccine delivery. World Health Organization recommends that girls, ages 9-13 years, get the human papilloma virus (HPV) vaccine. Global Alliance for Vaccines Initiative, which provides low-cost vaccine to eligible countries, requires that an additional intervention to be offered alongside the vaccine. We systematically searched and assessed the published literature in lower- and middle-income countries (...) ) menstrual hygiene education; (7) sexual and reproductive health education; (8) human immunodeficiency virus prevention activities; and (9) condom promotion, condom use skill building, and demonstration. We found limited evidence of consistent positive impact. Iron supplementation reduced iron-deficiency anemia and raised serum ferritin levels. Promotion of physical activity lowered blood pressure and reduced weight gain. Sexual and reproductive health and human immunodeficiency virus interventions

2015 The Journal of Adolescent Health

79. Vaccine allergy testing

and gelatin. A question in the Ask the Expert archives addresses this issue (4). There is commercial testing available for IgE to alpha-gal, but Dr. Cummins feels comfortable with administering vaccine in individuals who can tolerate dairy (4). Quadrivalent papilloma virus and Hepatitis B vaccines may contain residual Saccharomces cerevisiae (baker’s yeast), but sensitivity is not proven to be responsible for reactions (5). Finally, testing with the vaccine itself, recognizing you will not be able (...) other than anaphylactic allergies (e.g., a history of contact allergy to latex gloves), vaccines supplied in vials or syringes that contain dry natural rubber or rubber latex may be administered." (ACIP General Recommendations on Immunization. 2011). American Association of Nurse Anesthetists 222 South Prospect Avenue Park Ridge, IL 60068 www.aana.com "Draw medication directly from opened multidose vials (remove stoppers) if medications are not available in ampoules." Guidelines for the Management

2020 American Academy of Allergy, Asthma & Immunology - Ask the Expert

80. Knowledge, attitudes, practices and willingness to vaccinate in preparation for the introduction of HPV vaccines in Bamako, Mali. Full Text available with Trip Pro

Knowledge, attitudes, practices and willingness to vaccinate in preparation for the introduction of HPV vaccines in Bamako, Mali. Although screening for pre-cancerous cervical lesions and human papilloma virus (HPV) vaccination are accepted and effective means to prevent cervical cancer, women in Mali have limited access to these interventions. In addition, cervical cancer prevention by HPV vaccination has been controversial in some settings. To reduce cervical cancer prevalence and increase (...) HPV vaccine uptake, it is important to understand the level of knowledge about cervical cancer screening and practices related to vaccination in at-risk populations. In this study, the level of knowledge about HPV and cervical cancer and attitudes towards vaccination were assessed among 301 participants (male and female, adults and adolescents) in a house-to-house survey in two urban neighborhoods in Bamako, Mali. The survey was combined with a brief educational session on HPV. Prior

2017 PLoS ONE

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