How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

3,972 results for

Hip Injection

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

141. Analgesic Effect of Duloxetine on an Animal Model of Monosodium Iodoacetate-Induced Hip Osteoarthritis. (PubMed)

Analgesic Effect of Duloxetine on an Animal Model of Monosodium Iodoacetate-Induced Hip Osteoarthritis. We investigated the efficacy of duloxetine on hyperalgesia, histopathological and radiographic findings, pain-related sensory innervation of dorsal-root ganglia (DRG), and spinal changes in a rat model of induced hip osteoarthritis (OA). The right hip joints of male Sprague-Dawley rats (n = 6 rats/group) in the Sham group were injected with 25 μl of sterile saline and 25 μl of sterile saline (...) for ionized-calcium-binding adaptor molecule 1 (Iba1) in the dorsal horn of the spinal cord. MIA administration into the hip joint let to mechanical hyperalgesia of the ipsilateral hind paw (p < 0.05). A single injection of duloxetine significantly attenuated it in induced hip OA (p < 0.05) and suppressed the number of Iba1-ir microglia of the ipsilateral dorsal horn (p < 0.05). These results suggest that a single injection of duloxetine suppressed mechanical hyperalgesia and may influence the expression

2019 Journal of Orthopaedic Research

142. Randomised controlled trial: Epidural steroid injections are not effective for patients with lumbar spinal stenosis

were randomly assigned to either a standard ESI (glucocorticoids) with lidocaine, or an injection of lidocaine alone, with potential for a repeat study injection at 3 weeks. Twenty-six anaesthesiologists, physiatrists and radiologists experienced in epidural injections from 16 US sites performed the procedures. The primary outcomes assessed at 6 weeks were an average pain rating for buttock, hip or leg pain in the past week and functional impairment measured by the Roland-Morris Disability (...) Randomised controlled trial: Epidural steroid injections are not effective for patients with lumbar spinal stenosis Epidural steroid injections are not effective for patients with lumbar spinal stenosis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal

Full Text available with Trip Pro

2015 Evidence-Based Medicine

143. The efficacy of platelet-rich plasma injection in the management of hip osteoarthritis: a systematic review

The efficacy of platelet-rich plasma injection in the management of hip osteoarthritis: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation

2014 PROSPERO

144. Apixaban versus enoxaparin for thromboprophylaxis after total hip or knee arthroplasty: a meta-analysis of randomized controlled trials

Apixaban versus enoxaparin for thromboprophylaxis after total hip or knee arthroplasty: a meta-analysis of randomized controlled trials Apixaban versus enoxaparin for thromboprophylaxis after total hip or knee arthroplasty: a meta-analysis of randomized controlled trials Apixaban versus enoxaparin for thromboprophylaxis after total hip or knee arthroplasty: a meta-analysis of randomized controlled trials Li XM, Sun SG, Zhang WD CRD summary The authors concluded that available evidence suggested (...) that apixaban was more effective than recommended dose of enoxaparin and had a similar safety profile for thromboprophylaxis after hip and knee arthroplasty. The conclusions reflect the evidence presented and are reliable. Authors' objectives To compare the efficacy and safety of apixaban versus enoxaparin for prevention of venous thromboembolism after total hip or knee arthroplasty. Searching PubMed, The Cochrane Library, EMBASE, China Biological Medical Literature, Countries Journal full-text, VIP

2012 DARE.

145. Local Infiltration Analgesia in Hip and Knee Arthroplasty

of analgesics, such as opioids and nonsteroidal anti-inflammatory drugs (NSAIDs), and/or regional anesthetics, such as epidurals and femoral nerve blocks. (1-3) Pain management medications for patients undergoing total knee arthroplasty (TKA) or total hip arthroplasty (THA) can be administered through a number of different modalities such as oral, local injection, or epidural injection. (4) Local infiltration analgesia (LIA) is one such modality of pain management administered as a “cocktail (...) ((Intraarticular or knee* or hip? or intra-articular or periarticular or peri-articular or wound* or joint*) adj2 (injection* or infiltat* or infus* or instill*)).mp. [mp=ti, ab, tx, kw, ct, ot, sh, hw, tn, dm, mf, dv, nm, kf, ps, rs, ui] 18114 20 ((infiltra* or instill* or infus*) adj2 (analgesi* or an?esthesia*or ropivacaine or ketorolac or adrenaline or steroid* or magnesium sulphate or morphine or nonsteroidal anti-inflammatory or nsaid* or opiod* or anti-hyperalgesic* or pregabalin or s-ketamine

2013 Health Quality Ontario

146. Therapeutic hip injections: is the injection volume important? (PubMed)

Therapeutic hip injections: is the injection volume important? To assess whether an increased volume of local anaesthetic injection given with intra-articular steroids improves symptom relief in osteoarthritis of the hip.One hundred and ten patients with hip osteoarthritis were randomized into two groups (A and B). All patients were given 40 mg triamcinolone and 2 ml bupivicaine, and patients from group B were also given 6 ml of sterile water for injection. Change in WOMAC (Western Ontario (...) between the two groups at 3 months. There was also no statistical difference in pain symptoms between the two groups during the study period, measured at 2 weekly intervals. One hundred and two patients reached the study endpoint; eight patients who had bilateral hip injections were subsequently included in the analysis, and these patients did not alter the findings significantly.Published total injection volumes used for treating osteoarthritis of the hip with intra-articular steroids vary from 3

2012 Clinical radiology Controlled trial quality: uncertain

147. In Vitro Injection of Osteoporotic Cadaveric Femurs with a Triphasic Calcium-Based Implant Confers Immediate Biomechanical Integrity. (PubMed)

In Vitro Injection of Osteoporotic Cadaveric Femurs with a Triphasic Calcium-Based Implant Confers Immediate Biomechanical Integrity. Current pharmaceutical therapies can reduce hip fractures by up to 50%, but compliance to treatment is low and therapies take up to 18 months to reduce risk. Thus, alternative or complementary approaches to reduce the risk of hip fracture are needed. The AGN1 local osteo-enhancement procedure (LOEP) is one such alternative approach, as it is designed to locally (...) replace bone lost due to osteoporosis and provide immediate biomechanical benefit. This in vitro study evaluated the initial biomechanical impact of this treatment on human cadaveric femurs. We obtained 45 pairs of cadaveric femurs from women aged 77.8 ± 8.8 years. One femur of each pair was treated, while the contralateral femur served as an untreated control. Treatment included debridement, irrigation/suction, and injection of a triphasic calcium-based implant (AGN1). Mechanical testing

Full Text available with Trip Pro

2019 Journal of Orthopaedic Research

148. Effect of medications and epidural steroid injections on fractures in postmenopausal women with osteoporosis. (PubMed)

Effect of medications and epidural steroid injections on fractures in postmenopausal women with osteoporosis. Osteoporosis is a common problem, especially among postmenopausal women. Postmenopausal women with osteoporosis have major risk factors for osteoporotic fractures. The abuse of epidural steroid injections (ESIs) or the misunderstanding of their proper use could cause osteoporotic fractures. Therefore, we aimed to investigate whether ESIs are associated with osteoporotic fractures (...) %, respectively, in the hip joint.There was no significant difference in the incidences of osteoporotic fractures at the thoraco-lumbar spine and hip joint in postmenopausal women with osteoporosis between those who received ESIs (a mean of 6.2 ESIs, a cumulative dexamethasone dose of 31 mg) and those who did not, with both groups taking anti-osteoporotic medications for low back pain. Our data suggest that ESI treatment using a mean of 6.2 ESIs to deliver a maximum cumulative dexamethasone dose of 31 mg

Full Text available with Trip Pro

2019 Medicine

149. Daily subcutaneous Teriparatide injection increased bone mineral density of newly formed bone after tibia distraction osteogenesis, a randomized study. (PubMed)

Daily subcutaneous Teriparatide injection increased bone mineral density of newly formed bone after tibia distraction osteogenesis, a randomized study. Long bone defects are often treated by bone segment transport with the Ilizarov method requiring months spent with fixator mounted until bony consolidation of the newly formed bone. Shortening of consolidation would allow earlier fixator removal and earlier return to work. In pre-clinical studies parathyroid hormone, increased bone mineral (...) density and mechanical properties of regenerate bone formed during distraction osteogenesis. Clinical studies showed that Teriparatide accelerated fracture healing in patients with osteoporotic fracture of the pelvis, hip, wrist and shoulder. We hypothesized that rhPTH(1-34) (Teriparatide) administered to patients who had undergone distraction osteogenesis, would increase mineralization of the regenerate formed during the consolidation phase. Sixteen patients with tibial defects after infection

2019 Injury Controlled trial quality: uncertain

150. Effect of liraglutide on anthropometric measurements, sagittal abdominal diameter and adiponectin levels in people with type 2 diabetes treated with multiple daily insulin injections: evaluations from a randomized trial (MDI-liraglutide study 5). (PubMed)

diameter, waist circumference, waist-to-hip ratio and adiponectin levels in people with type 2 diabetes (T2D) treated with multiple daily insulin injections (MDI).In the multicentre, double-blind, placebo-controlled MDI-liraglutide trial, 124 individuals with T2D treated with MDI were randomized to either liraglutide or placebo. Basal values of weight, waist circumference, waist-to-hip ratio, sagittal abdominal diameter and adiponectin were compared with measurements at 12 and 24 weeks after (...) Effect of liraglutide on anthropometric measurements, sagittal abdominal diameter and adiponectin levels in people with type 2 diabetes treated with multiple daily insulin injections: evaluations from a randomized trial (MDI-liraglutide study 5). Use of the glucagon-like peptide 1 receptor agonist liraglutide has been shown to reduce weight. Different types of anthropometric measurements can be used to measure adiposity. This study evaluated the effect of liraglutide on sagittal abdominal

Full Text available with Trip Pro

2019 Obesity science & practice Controlled trial quality: uncertain

151. Platelet-Rich plasma Injection Management for Ankle osteoarthritis study (PRIMA): protocol of a Dutch multicentre, stratified, block-randomised, double-blind, placebo-controlled trial. (PubMed)

Platelet-Rich plasma Injection Management for Ankle osteoarthritis study (PRIMA): protocol of a Dutch multicentre, stratified, block-randomised, double-blind, placebo-controlled trial. Platelet-rich plasma (PRP) is a potentially efficacious treatment for ankle osteoarthritis (OA), but its use has not been examined in high-quality studies. Systematic reviews show that PRP injections significantly decrease pain and improve function in patients with knee OA. Ankle OA is more common than hip (...) or knee OA in the young active population; with a prevalence of 3.4%.PRP injections in ankle OA are shown to be safe and improve quality of life over time, but no randomised controlled trial has been conducted. Our randomised controlled trial will evaluate the efficacy of PRP injections for symptom reduction and functional improvement, compared with placebo, in the treatment of ankle (talocrural) OA.We will conduct the Platelet-Rich plasma Injection Management for Ankle OA study: a multicentre

Full Text available with Trip Pro

2019 BMJ open

152. Ranibizumab injection - Macular edema, secondary to retinal vein occlusion

Ranibizumab injection - Macular edema, secondary to retinal vein occlusion Common Drug Review CDEC Meeting – September 19, 2012 Notice of CDEC Final Recommendation – October 18, 2012 Page 1 of 6 © 2012 CADTH CDEC FINAL RECOMMENDATION RANIBIZUMAB (Lucentis – Novartis Pharmaceuticals Canada Inc.) New Indication: Macular Edema Secondary to Retinal Vein Occlusion Recommendation: The Canadian Drug Expert Committee (CDEC) recommends that ranibizumab be listed for patients meeting both (...) edema secondary to non-ischemic BRVO or CRVO (the BRAVO and CRUISE studies respectively), compared with sham, ranibizumab resulted in statistically significantly greater improvement in best corrected visual acuity at six months. 2. The cost-effectiveness estimates for ranibizumab were sensitive to changes in assumptions regarding the durability of the treatment effect, and the frequency and duration of ranibizumab use. When CDR considered higher numbers of injections, treatment duration beyond two

2012 Canadian Agency for Drugs and Technologies in Health - Common Drug Review

153. AbobotulinumtoxinA: A New Therapy for Hip Osteoarthritis. A Prospective Randomized Double-Blind Multicenter Study. (PubMed)

AbobotulinumtoxinA: A New Therapy for Hip Osteoarthritis. A Prospective Randomized Double-Blind Multicenter Study. Background: Hip Osteoarthritis (OA) causes pain and disability. Here we evaluate abobotulinumtoxinA (Dysport®) (AboBoNT-A) injections versus placebo as a novel treatment option to improve hip range of motion, pain and quality of life. Methods: This prospective randomized double-blind multicenter study (EudraCT # 2012-004890-25) recruited 46 outpatients with hip OA who were (...) randomized 2:1 to the Treatment Group (TG; 31 subjects), or the Placebo Group (PG; 15 subjects). The TG received 400 U of AboBoNT-A injected into the adductor muscles, and the PG received placebo solution. The primary endpoints were the difference in Harris Hip Score (HHS) and Visual Analogic Scale for pain (VAS) at Week 4 between groups (TG vs. PG). Secondary endpoints were the change from baseline in HHS, VAS pain, Medical Research Council scale for muscle strength (MRC) and Short Form scale (SF-36

Full Text available with Trip Pro

2018 Toxins Controlled trial quality: predicted high

154. Combination of magnesium sulphate and ropivacaine epidural analgesia for hip arthroplasty in dogs. (PubMed)

undergoing hip arthroplasty were allocated randomly to either group C (control, 1 mg kg-1epidural ropivacaine) or group M (magnesium, epidural injection of 1 mg kg-1 ropivacaine and 2 mg kg-1magnesium sulphate).All dogs were premedicated with intramuscular acepromazine. General anaesthesia was induced with propofol and maintained with isoflurane in oxygen. Intraoperatively, nociception was assessed based on changes in heart rate, respiratory rate and mean arterial pressure above baseline values (...) Combination of magnesium sulphate and ropivacaine epidural analgesia for hip arthroplasty in dogs. The aim of this study was to determine whether lumbosacral epidural administration of magnesium sulphate added to ropivacaine prolongs and improves perioperative analgesia, without adverse effects on motor block duration or hind limb neurological function, in dogs undergoing hip arthroplasty.Investigator-blind, controlled, randomized, prospective clinical trial.A group of 20 client-owned dogs

Full Text available with Trip Pro

2018 Veterinary anaesthesia and analgesia Controlled trial quality: uncertain

155. Unusual indication of Cell therapy for hip osteonecrosis after pregnancy (PubMed)

(MSC) injection obtained from bone marrow concentration. The average total number of MSCs (counted as number of colonies forming units-fibroblast) injected in the hip was 185 000 ± 65 000 cells (range 95 000-240 000 cells).At the most recent follow-up (average 15 years after hip surgery, range 8-25 years), among the 145 hips included in the study, 4 hips (2.7%) had collapsed and were treated with total hip arthroplasty (THA). Thirty-two of the 94 stage I had progressed to stage II; and 4 of the 51 (...) Unusual indication of Cell therapy for hip osteonecrosis after pregnancy Osteonecrosis is a rare event during or after pregnancy. Due to the low number of cases, there is no report of long-term results after conservative surgery in this population.From 1992 to 2010, 145 consecutive female patients with unilateral symptomatic (94 stage I and 51 stage II) left hip osteonecrosis (ON) related to pregnancy were treated between 4 and 16 months after delivery with percutaneous mesenchymal stem cell

Full Text available with Trip Pro

2018 SICOT-J

156. Silicone-Induced Foreign Body Reaction: An Unusual Differential Diagnosis of Posterolateral Hip Pain (PubMed)

Silicone-Induced Foreign Body Reaction: An Unusual Differential Diagnosis of Posterolateral Hip Pain Silicone injection is commonly used for soft tissue augmentation for esthetic purposes. It is not without complications.We present a case of a 31-year-old woman presenting with refractory left lateral hip pain. Magnetic resonance imaging of the patient's pelvis revealed innumerable small low signal foci throughout the gluteus maximus and overlying subcutaneous fat bilaterally consistent (...) with injectable material, possibly silicone.This case report emphasizes that silicone-induced granulomatosis must be considered in the differential diagnosis of hip pain when evaluating a patient who has had access to plastic surgery or clandestine operators.

Full Text available with Trip Pro

2018 Case reports in medicine

157. Traumatic Obturator Hip Dislocation with Marginal Femoral Head Fracture in a 15-Year-Old Adolescent: A High-Energy Trauma—A Case Report and a Review of the Literature (PubMed)

showed an avascular femoral head necrosis, for which we performed multiple retrograde femoral head drilling, completed by the injection of autologue stem cells from the iliaq crest. One year later, the patient has no hip pain, no joint limitation, and can practice BMX at a high level again. The purpose of this report is to make the physicians aware of this rare problem that may be damaging for hip function, especially in young people. (...) Traumatic Obturator Hip Dislocation with Marginal Femoral Head Fracture in a 15-Year-Old Adolescent: A High-Energy Trauma—A Case Report and a Review of the Literature We report the case of a 15-year-old boy brought to the emergency department after a bike accident, complaining of an isolated left hip pain. The X-rays showed an obturator hip dislocation treated by closed reduction under general anaesthesia, followed by 6 weeks of discharge. The follow-up MRI performed 6 weeks after the trauma

Full Text available with Trip Pro

2018 Case reports in orthopedics

158. Ultrasound-guided continuous fascia iliaca compartment block for pre-operative pain control in very elderly patients with hip fracture: A randomized controlled trial (PubMed)

Ultrasound-guided continuous fascia iliaca compartment block for pre-operative pain control in very elderly patients with hip fracture: A randomized controlled trial The present study presented the results of a prospective, randomized controlled trial. The present study enrolled 98 very elderly patients with hip fractures, complicated with at least one cardiovascular, neurological or pulmonary disease, of whom 10 patients were excluded. A total of 88 patients were randomly assigned into 2 (...) groups: i) The control group, receiving traditional analgesia including 50 mg Tramadol and 500 mg paracetamol orally three times a day from admission to surgery; and ii) the study group, receiving ultrasound-guided continuous fascia iliaca compartment block (CFICB), a single 50 ml 0.4% ropivacaine injection with continuous infusion of 0.2% ropivacaine at a dose of 5 ml/h from admission to surgery. The primary outcome measure of pain relief or pain intensity was assessed preoperatively and up to 48 h

Full Text available with Trip Pro

2018 Experimental and therapeutic medicine Controlled trial quality: uncertain

159. Extracapsular local infiltration analgesia in hip arthroscopy: a retrospective study (PubMed)

arthroscopy is unclear. The purpose of this retrospective study is to determine the efficacy of a single extracapsular injection of bupivacaine-epinephrine during hip arthroscopy in reducing the rate of elective postoperative femoral nerve blocks. A retrospective review of 100 consecutive patients who underwent primary hip arthroscopy at a single medical center was performed. The control group consisted of 50 patients before the implementation of the current LIA protocol, whereas another 50 patients (...) Extracapsular local infiltration analgesia in hip arthroscopy: a retrospective study Many hip arthroscopy patients experience significant pain in the immediate postoperative period. Although peripheral nerve blocks have demonstrated efficacy in alleviating some of this pain, they come with significant costs. Local infiltration analgesia (LIA) may be a significantly cheaper and efficacious treatment modality. Although LIA has been well studied in hip and knee arthroplasty, its efficacy in hip

Full Text available with Trip Pro

2018 Journal of hip preservation surgery

160. Safety Profile and Short-term Outcomes of BST-CarGel as an Adjunct to Microfracture for the Treatment of Chondral Lesions of the Hip (PubMed)

Safety Profile and Short-term Outcomes of BST-CarGel as an Adjunct to Microfracture for the Treatment of Chondral Lesions of the Hip Acetabular cartilage lesions are a common abnormality found in patients undergoing hip arthroscopic surgery and may cause pain and functional limitations. Several strategies have been developed to treat chondral defects, with no overwhelming success. Recently, BST-CarGel has gained interest as a scaffolding material that can be injected into the microfracture site (...) to stabilize the clot and facilitate cartilage repair.To perform a retrospective analysis of prospectively collected data to evaluate the safety profile and short-term clinical and radiographic outcomes of patients treated arthroscopically with BST-CarGel for acetabular chondral defects in conjunction with microfracture.Case series; Level of evidence, 4.A retrospective chart review was performed on all patients who underwent hip arthroscopic surgery by the senior surgeon to identify those who had BST

Full Text available with Trip Pro

2018 Orthopaedic journal of sports medicine

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>