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Hip Injection

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81. Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. Full Text available with Trip Pro

Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. The effectiveness of intra-articular platelet-rich plasma (PRP) injections has been evaluated in knee chondroplasty and osteoarthritis (OA); however, little evidence of its efficacy in hip OA exists.To compare the therapeutic efficacy of autologous PRP, hyaluronic acid (HA), or a combination of both (PRP+HA) in hip OA.Randomized (...) treatment. Secondary outcome measures were the Harris Hip Score, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and concentration of growth factors in PRP and their correlation with clinical outcomes. Clinical outcomes were evaluated by assessors and collectors blinded to the type of treatment administered.A total of 111 patients were randomly assigned to 3 groups and received 3 weekly injections of either PRP (44 patients), PRP+HA (31 patients), or HA (36 patients). At all

2016 The American Journal of Sports Medicine Controlled trial quality: predicted high

82. Assessment of Intraoperative Intra-articular Morphine and Clonidine Injection in the Acute Postoperative Period After Hip Arthroscopy Full Text available with Trip Pro

Assessment of Intraoperative Intra-articular Morphine and Clonidine Injection in the Acute Postoperative Period After Hip Arthroscopy Previous authors have suggested that intra-articular morphine and clonidine injections after knee arthroscopy have demonstrated equivocal analgesic effect in comparison with bupivacaine while circumventing the issue of chondrotoxicity. There have been no studies evaluating the effect of intra-articular morphine after hip arthroscopy.To evaluate the efficacy (...) discharge or in visual analog pain scores recorded immediately postoperatively and at 1 hour after surgery.Intraoperative intra-articular injection of morphine and clonidine significantly reduced the narcotic requirement during the postsurgical recovery period after hip arthroscopy. The reduction in postsurgical opioids may decrease adverse effects, improve overall pain management, and lead to better quality of recovery and improved patient satisfaction.

2016 Orthopaedic journal of sports medicine

83. Outcomes After Diagnostic Hip Injection. (Abstract)

Outcomes After Diagnostic Hip Injection. To provide a comprehensive review of outcomes associated with local anesthetic (LA) or LA and corticosteroid (CS) diagnostic hip injections, and how well response predicts subsequent operative success.A systematic review from database (PubMed, Medline, Scopus, Embase) inception to January 2015 for English-language articles reporting primary patient outcomes data was performed, excluding studies with >50% underlying osteoarthritis. Studies were assessed (...) by 2 reviewers who collected pertinent data.Seven studies were included, reporting on a total 337 patients undergoing diagnostic hip injection. The mean age was 34.4 years, with 5 studies reporting 94 (35.2%) males and 173 (64.8%) females. One study examined the rate of pain relief with LA (92.5%); 2 CS studies reported relief on a scale from 0% to 100% (no to complete relief), ranging from 61% to 82.3%; and 3 studies used 10-point pain scales, with a CS study noting a pain score of 1.0, an LA

2016 Arthroscopy

84. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations Full Text available with Trip Pro

Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations: Acta Orthopaedica: Vol 0, No 0 | Search in: Journal 6,974 Views 0 CrossRef citations to date Altmetric Articles Consensus statement for perioperative care in total (...) hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS ® ) Society recommendations , , , , , , & Published online: 30 Oct 2019 In this article Articles Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS ® ) Society recommendations Ljungqvist O , Scott M , Fearon K C . Enhanced Recovery After Surgery: a review . JAMA Surg 2017 ; 152(3): 292 – 8 . , , , ). For total hip (THR

2019 ERAS Society

85. Utility of Intra-articular Hip Injections for Femoroacetabular Impingement: A Systematic Review. Full Text available with Trip Pro

Utility of Intra-articular Hip Injections for Femoroacetabular Impingement: A Systematic Review. Femoroacetabular impingement (FAI) is a condition that is becoming increasingly recognized as a common etiology of hip pain in athletes, adolescents, and adults. However, history and clinical examination are often inconclusive in reaching a diagnosis, while imaging often detects asymptomatic abnormalities. Treatment has traditionally been limited to surgery, with the role of conservative management (...) remaining unclear.To evaluate the utility of the intra-articular hip injection in the diagnosis and management of FAI.Systematic review; Level of evidence, 4.MEDLINE, EMBASE, and PubMed databases were screened in duplicate for studies published between January 1946 and January 2014. Search terms included femoroacetabular impingement, hip impingement, and intra-articular injection. Quality assessment using the Methodological Index for Non-Randomized Studies (MINORS) scale was completed for all included

2015 Orthopaedic journal of sports medicine

86. Local infiltration analgesia is not improved by postoperative intra-articular bolus injections for pain after total hip arthroplasty. (Abstract)

Local infiltration analgesia is not improved by postoperative intra-articular bolus injections for pain after total hip arthroplasty. The effect of postoperative intra-articular bolus injections after total hip arthroplasty (THA) remains unclear. We tested the hypothesis that intra-articular bolus injections administered every 6 hours after surgery during the first 24 hours would significantly improve analgesia after THA.80 patients undergoing THA received high-volume local infiltration (...) analgesia (LIA; 200 mg ropivacaine and 30 mg ketorolac) followed by 4 intra-articular injections with either ropivacaine (100 mg) and ketorolac (15 mg) (the treatment group) or saline (the control group). The intra-articular injections were combined with 4 intravenous injections of either saline (treatment group) or 15 mg ketorolac (control group). All patients received morphine as patient-controlled analgesia (PCA). The primary outcome was consumption of intravenous morphine PCA and secondary outcomes

2015 Acta Orthopaedica Controlled trial quality: uncertain

87. Local infiltration analgesia is not improved by postoperative intra-articular bolus injections for pain after total hip arthroplasty. (Abstract)

Local infiltration analgesia is not improved by postoperative intra-articular bolus injections for pain after total hip arthroplasty.

2015 Acta Orthopaedica

88. Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy

Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02530151 Recruitment Status : Completed First Posted : August 20, 2015 Last Update Posted : September 13, 2017 Sponsor: Northwestern University

2015 Clinical Trials

89. A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip Arthroplasty

A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip Arthroplasty A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip Arthroplasty - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip Arthroplasty The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02543801 Recruitment Status : Completed First Posted : September 7, 2015 Last Update Posted : February 27, 2019 Sponsor: Kootenai Health

2015 Clinical Trials

90. Patient-controlled epidural analgesia or multimodal pain regimen with periarticular injection after total hip arthroplasty: a randomized, double-blind, placebo-controlled study. Full Text available with Trip Pro

Patient-controlled epidural analgesia or multimodal pain regimen with periarticular injection after total hip arthroplasty: a randomized, double-blind, placebo-controlled study. The optimal postoperative analgesia after primary total hip arthroplasty remains in question. This randomized, double-blind, placebo-controlled study compared the use of patient-controlled epidural analgesia (PCEA) with use of a multimodal pain regimen including periarticular injection (PAI). We hypothesized that PAI

2015 The Journal of Bone and Joint Surgery. American Volume Controlled trial quality: predicted high

91. The Efficacy of Platelet-Rich Plasma Injection in the Management of Hip Osteoarthritis: A Systematic Review Protocol. (Abstract)

The Efficacy of Platelet-Rich Plasma Injection in the Management of Hip Osteoarthritis: A Systematic Review Protocol. 26206142 2018 01 26 2018 12 02 1557-0681 14 2 2016 06 Musculoskeletal care Musculoskeletal Care The Efficacy of Platelet-Rich Plasma Injection in the Management of Hip Osteoarthritis: A Systematic Review Protocol. 121-5 10.1002/msc.1115 Medina-Porqueres Ivan I Department of Physical Therapy, University of Malaga, Malaga, Spain. Alvarez-Juarez Patricia P Department of Physical (...) Therapy, University of Malaga, Malaga, Spain. eng Journal Article 2015 07 24 England Musculoskeletal Care 101181344 1478-2189 IM Humans Injections, Intra-Articular Osteoarthritis, Hip therapy Platelet-Rich Plasma Systematic Reviews as Topic 2015 7 25 6 0 2015 7 25 6 0 2018 1 27 6 0 ppublish 26206142 10.1002/msc.1115

2015 Musculoskeletal care

92. A Novel and Practical Chromatographic “Fingerprint-ROC-SVM” Strategy Applied to Quality Analysis of Traditional Chinese Medicine Injections: Using KuDieZi Injection as a Case Study Full Text available with Trip Pro

, with the accuracy of 97.06%, was established by the optimized characteristic peaks and applied to monitor the quality of KDZ injection. As a result, the established model could sensitively and accurately distinguish the qualified products (QPs) with the unqualified products (UPs), high-temperature processed samples (HTPs) and high-illumination processed samples (HIPs) of KDZ injection, and the prediction accuracy was 100.00%, 93.75% and 100.00%, respectively. Furthermore, through the comparison with other (...) A Novel and Practical Chromatographic “Fingerprint-ROC-SVM” Strategy Applied to Quality Analysis of Traditional Chinese Medicine Injections: Using KuDieZi Injection as a Case Study Fingerprinting is widely and commonly used in the quality control of traditional Chinese medicine (TCM) injections. However, current studies informed that the fingerprint similarity evaluation was less sensitive and easily generated false positive results. For this reason, a novel and practical chromatographic

2017 Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

93. A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease

A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information (...) . Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does

2017 Clinical Trials

94. Efficacy of lateral- versus medial-approach hip joint capsule denervation as surgical treatments of the hip joint pain; a neuronal tract tracing study in the sheep. Full Text available with Trip Pro

tracing of sensory neurons innervating the capsule.Twenty adult male sheep (30-40 kg of body weight; Polish merino breed) were used in the study.The hip joint was denervated from medial (n = 5) or lateral (n = 5) surgical approaches. Immediately after denervation, the retrograde neural tract tracer Fast Blue (FB) was injected into the HJC. An additional ten animals (n = 5 for medial and n = 5 for lateral approach) received the same treatment without HJC denervation to provide the appropriate (...) Efficacy of lateral- versus medial-approach hip joint capsule denervation as surgical treatments of the hip joint pain; a neuronal tract tracing study in the sheep. To evaluate efficacy of denervation of the of the hip joint capsule (HJC), as a treatment of hip joint pain. Specifically, we tested the hypothesis that HJC denervation will significantly reduce the number of sensory neurons innervating the capsule.Denervation of the HJC from a medial or lateral approach was followed by retrograde

2018 PLoS ONE

95. Ranibizumab injection - Macular edema, secondary to retinal vein occlusion

Ranibizumab injection - Macular edema, secondary to retinal vein occlusion Common Drug Review CDEC Meeting – September 19, 2012 Notice of CDEC Final Recommendation – October 18, 2012 Page 1 of 6 © 2012 CADTH CDEC FINAL RECOMMENDATION RANIBIZUMAB (Lucentis – Novartis Pharmaceuticals Canada Inc.) New Indication: Macular Edema Secondary to Retinal Vein Occlusion Recommendation: The Canadian Drug Expert Committee (CDEC) recommends that ranibizumab be listed for patients meeting both (...) edema secondary to non-ischemic BRVO or CRVO (the BRAVO and CRUISE studies respectively), compared with sham, ranibizumab resulted in statistically significantly greater improvement in best corrected visual acuity at six months. 2. The cost-effectiveness estimates for ranibizumab were sensitive to changes in assumptions regarding the durability of the treatment effect, and the frequency and duration of ranibizumab use. When CDR considered higher numbers of injections, treatment duration beyond two

2012 Canadian Agency for Drugs and Technologies in Health - Common Drug Review

96. Can a Periarticular Levobupivacaine Injection Reduce Postoperative Opiate Consumption During Primary Hip Arthroplasty? Full Text available with Trip Pro

Can a Periarticular Levobupivacaine Injection Reduce Postoperative Opiate Consumption During Primary Hip Arthroplasty? Several reports have confirmed the ability of intraoperative periarticular injections to control pain after THA. However, these studies used differing combinations of analgesic agents and the contribution of each, including the local anesthetic agent, is uncertain. Understanding the independent effects of the various agents could assist in improved pain management after (...) in the levobupivacaine group, most notable in the first 12 hours after surgery: treatment group 11.5 mg vs control group 21.2 mg. We observed no differences in the frequency of postoperative nausea and vomiting or urinary retention.Our observations suggest periarticular injection of levobupivacaine can supplement available postoperative analgesic techniques and reduce postoperative morphine requirements after THA.Level I, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

2012 EvidenceUpdates Controlled trial quality: predicted high

97. American Association of Hip and Knee Surgeons Clinical Practice Guideline on Tranexamic Acid in Total Joint Arthroplasty

, Lopez-Picado A, Remon M, Fondarella A, Iriarte I, Bastida R, Rodríguez-Gascón A, Achaerandio M, Iturricastillo M, Aizpuru F, Valero C, Tobalina R, Hernanz R. Tranexamic Acid Compared with Placebo for Reducing Total Blood Loss in Hip Replacement Surgery: A Randomized Clinical Trial. In: Anesthesia and analgesia. 986. 2016 9. Lin P, Hsu C, Huang C, Chen W, Wang J. The blood-saving effect of tranexamic acid in minimally invasive total knee replacement: is an additional pre-operative injection effective (...) American Association of Hip and Knee Surgeons Clinical Practice Guideline on Tranexamic Acid in Total Joint Arthroplasty Tranexamic Acid in Total Joint Arthroplasty: The Endorsed Clinical Practice Guides of the American Association of Hip and Knee Surgeons, American Society of Regional Anesthesia and Pain Medicine, American Academy of Orthopaedic Surgeons, The Hip Society, and The Knee Society Fillingham YA 1 , Ramkumar DB 2 , Jevsevar DS 2 , Yates AJ 3 , Sayeed SA 4 , Sah AP 5 , Bini SA 6

2018 American Academy of Orthopaedic Surgeons

98. Monoclonal Antibodies for Osteoarthritis of the Hip or Knee

therapeutic options include non-pharmacologic therapy and topical analgesics, followed by oral analgesics and injectable agents, followed by surgery for end-stage disease. OA typically affects the knees, hips, hands, spine, and feet. Treatment with anti-nerve growth factors monoclonal antibodies (anti-NGFs) may improve joint pain and physical function, as nerve growth factor is associated with chronic pain conditions, and is elevated in the joints of patients with osteoarthritis. Within the indication (...) investigated as an intravenous infusion; a subcutaneous injection was subsequently developed. 18-26 The doses used in the completed phase III clinical trials for IV tanezumab were 2.5 mg, 5 mg, or 10 mg administered every eight weeks. 13 The doses used in the ongoing phase III clinical trials for SC tanezumab are 2.5 mg and 5 mg, administered every eight weeks. 39-41 Target Population For OA, tanezumab has been studied in adults with hip or knee OA who do not respond to or who are intolerant to currently

2018 CADTH - Issues in Emerging Health Technologies

99. Guideline for the management of knee and hip osteoarthritis

OA, with monitoring of possible adverse effects, then discontinue use if not effective. • Corticosteroid injections could be offered for short-term symptom relief for some people with knee and/or hip OA, but care should be taken with repeated injections because of potential harm. • Duloxetine could be considered for some people with knee and/or hip OA when other forms of pain relief are inadequate. • There is a strong recommendation against the use of the following – oral and transdermal opioids (...) – viscosupplementation injection for hip OA – doxycycline – strontium ranelate – interleukin-1 (IL-1) inhibitors – stem cell therapy. • There is a conditional recommendation against the use of the following – capsaicin for knee and/or hip OA – bisphosphonates – calcitonin – anti-nerve growth factor (NGF) – colchicine – methotrexate – viscosupplementation injection for knee OA – dextrose prolotherapy – omega 3 fatty acids – diacerein.3 Guideline for the management of knee and hip osteoarthritis Second edition • Due

2018 Clinical Practice Guidelines Portal

100. Glucocorticoid injections for greater trochanteric pain syndrome: a randomised double-blind placebo-controlled (GLUTEAL) trial. (Abstract)

2011 and May 2015. Inclusion criteria included lateral hip pain (LHP) for greater than 1 month, a LHP score of ≥ 4/10 and typical LHP reproduced by palpation of the greater trochanter. Participants were randomised in a 1:1 ratio to injection with a combination of local anaesthetic and GC (intervention) or injection with normal saline solution (placebo). The primary outcome of interest was the difference in pain intensity at 4 weeks post-injection between the two groups. Patients were followed for 6 (...) Glucocorticoid injections for greater trochanteric pain syndrome: a randomised double-blind placebo-controlled (GLUTEAL) trial. Small observational studies suggest that local glucocorticoid (GC) injection may be effective in the management of the greater trochanteric pain syndrome (GTPS). The objective was to perform the first randomised double-blind placebo-controlled trial to investigate the efficacy of local GC injection in the management of GTPS. The trial was conducted between November

2018 Clinical rheumatology Controlled trial quality: predicted high

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