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Hip Injection

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41. Retention of Human-Induced Pluripotent Stem Cells (hiPS) With Injectable HA Hydrogels for Vocal Fold Engineering. (PubMed)

Retention of Human-Induced Pluripotent Stem Cells (hiPS) With Injectable HA Hydrogels for Vocal Fold Engineering. One prospective treatment option for vocal fold scarring is regeneration with an engineered scaffold containing induced pluripotent stem cells (iPS). In the present study, we investigated the feasibility of utilizing an injectable hyaluronic acid (HA) scaffold encapsulated with human-iPS cell (hiPS) for regeneration of vocal folds.Thirty athymic nude rats underwent unilateral vocal (...) fold injury. Contralateral vocal folds served as uninjured controls. Hyaluronic acid hydrogel scaffold, HA hydrogel scaffold containing hiPS, and HA hydrogel scaffold containing hiPS with epidermal growth factor (EGF) were injected in both vocal folds immediately after surgery. One and 2 weeks after injection, larynges were excised for histology, immunohistochemistry, and fluorescence in situ hybridization (FISH).Presence of HA hydrogel was confirmed in vocal folds 1 and 2 weeks post injection

2017 Rhinology and Laryngology

42. A Cadaveric Study of Ultrasound-Guided Subpectineal Injectate Spread Around the Obturator Nerve and Its Hip Articular Branches. (PubMed)

A Cadaveric Study of Ultrasound-Guided Subpectineal Injectate Spread Around the Obturator Nerve and Its Hip Articular Branches. The femoral and obturator nerves are assumed to account for the primary nociceptive innervation of the hip joint capsule. The fascia iliaca compartment block and the so-called 3-in-1-block have been used in patients with hip fracture based on a presumption that local anesthetic spreads to anesthetize both the femoral and the obturator nerves. Evidence demonstrates (...) that this presumption is unfounded, and knowledge about the analgesic effect of obturator nerve blockade in hip fracture patients presurgically is thus nonexistent. The objectives of this cadaveric study were to investigate the proximal spread of the injectate resulting from the administration of an ultrasound-guided obturator nerve block and to evaluate the spread around the obturator nerve branches to the hip joint capsule.Fifteen milliliters of methylene blue was injected into the interfascial plane between

2017 Regional Anesthesia and Pain Medicine

43. Pain Control in Hip Arthroscopy: Comparing Lumbar Plexus Versus Peri-capsular Injection

Pain Control in Hip Arthroscopy: Comparing Lumbar Plexus Versus Peri-capsular Injection Pain Control in Hip Arthroscopy: Comparing Lumbar Plexus Versus Peri-capsular Injection - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Pain Control in Hip Arthroscopy: Comparing Lumbar Plexus Versus Peri-capsular Injection The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03244631 Recruitment Status : Active, not recruiting First Posted : August 9, 2017 Last Update Posted : March 22, 2019 Sponsor: Washington

2017 Clinical Trials

44. Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty. Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03347266 Recruitment Status : Completed First

2017 Clinical Trials

45. Ultrasound Diagnostic and Therapeutic Injections of the Hip and Groin (PubMed)

Ultrasound Diagnostic and Therapeutic Injections of the Hip and Groin Hip and groin pain often presents a diagnostic and therapeutic challenge. The differential diagnosis is extensive, comprising intra-articular and extra-articular pathology and referred pain from lumbar spine, knee and elsewhere in the pelvis. Various ultrasound-guided techniques have been described in the hip and groin region for diagnostic and therapeutic purposes. Ultrasound has many advantages over other imaging modalities (...) , including portability, lack of ionising radiation and real-time visualisation of soft tissues and neurovascular structures. Many studies have demonstrated the safety, accuracy and efficacy of ultrasound-guided techniques, although there is lack of standardisation regarding the injectates used and long-term benefit remains uncertain.

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2017 Journal of the Belgian Society of Radiology

46. Effects of periarticular injection on analgesic effects and NSAID use in total knee arthroplasty and total hip arthroplasty (PubMed)

Effects of periarticular injection on analgesic effects and NSAID use in total knee arthroplasty and total hip arthroplasty This study examined periarticular multimodal drug injection and the use of nonsteroidal anti-inflammatory drugs for an early analgesic effect after total knee arthroplasty and total hip arthroplasty. Patient satisfaction and benefits from the treatment were also assessed.A total of 110 patients who were scheduled to undergo total knee arthroplasty and 86 patients who were (...) scheduled to undergo total hip arthroplasty were divided into two groups, the study group and the control group. The study group received a periarticular multimodal drug injection during surgery. The control group received an equal volume of normal saline. All patients received an analgesia pump and a moderate dose of nonsteroidal anti-inflammatory drugs. Resting and motion Numeric Rating Scale scores, the Western Ontario and McMaster Universities Arthritis Index, knee or hip joint range of motion

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2017 Clinics

47. Retrospective Analysis of the Accuracy of Ultrasound-Guided Magnetic Resonance Arthrogram Injections of the Hip in the Office Setting (PubMed)

Retrospective Analysis of the Accuracy of Ultrasound-Guided Magnetic Resonance Arthrogram Injections of the Hip in the Office Setting Ultrasound (US)-guided intra-articular hip injections have been proposed in the literature to be accurate, reliable, and safe alternatives to fluoroscopy-guided injections.To evaluate the accuracy of US-guided magnetic resonance (MR) arthrogram injections of the hip performed in the office setting by a single orthopaedic surgeon and elucidate the potential (...) effects that patient age, sex, and body mass index (BMI) have on contrast placement.Case series; Level of evidence, 4.From a review of the senior author's office database, 89 patients (101 hips) who had US-guided MR arthrogram injections performed between December 2014 and June 2016 were identified. Official radiology reports were evaluated to determine whether extra-articular contrast was noted. Patient variables, including BMI, age, and sex, were evaluated between patients who had inappropriately

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2017 Orthopaedic journal of sports medicine

48. Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement

Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03119038 Recruitment Status : Terminated (Investigator no longer actively pursuing this study.) First Posted : April 18

2017 Clinical Trials

49. Outcomes of intra-articular corticosteroid injections for adolescents with hip pain (PubMed)

Outcomes of intra-articular corticosteroid injections for adolescents with hip pain Intra-articular injection of corticosteroid and anesthetic (CSI) is a useful diagnostic tool for hip pain secondary to labral tears or femoroacetabular impingement (FAI). However, the effectiveness of CSI as a stand-alone treatment for hip pain in adolescents is unknown. The purpose of this study is to evaluate the use of CSI for the treatment of hip pain and determine factors that may affect outcomes after (...) injection. Retrospective analysis of 18 patients and 19 hips that underwent fluoroscopic guided hip injection for the treatment of pain at a single institution from 2012 to 2015 was carried out in this study. Mean age at the time of injection was 15.1 years (range 13-17) with mean follow-up of 29.4 months. Fifty-two percent (10/19 hips) went on to surgery after the injection. Average time to surgical conversion was 12.8 months after CSI. Cam or pincer morphologies were present in 90% (9/10 hips

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2017 Journal of hip preservation surgery

50. Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Total Hip Arthroplasty: A Three-Arm Randomized Clinical Trial. (PubMed)

Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Total Hip Arthroplasty: A Three-Arm Randomized Clinical Trial. Debate surrounds the issue of whether peripheral nerve blockade or periarticular infiltration (PAI) should be employed within a contemporary, comprehensive multimodal analgesia pathway for total hip arthroplasty. We hypothesized that patients treated with a continuous posterior lumbar plexus block (PNB) would (...) report less pain and consume less opioid medication than those treated with PAI.This investigator-initiated, independently funded, 3-arm randomized clinical trial (RCT) performed at a single high-volume institution compared postoperative analgesia interventions for elective, unilateral primary total hip arthroplasty: (1) PNB; (2) PAI with ropivacaine, ketorolac, and epinephrine (PAI-R); and (3) PAI with liposomal bupivacaine, ketorolac, and epinephrine (PAI-L) using computerized randomization

2017 The Journal of Bone and Joint Surgery. American Volume Controlled trial quality: predicted high

51. Total Hip Arthroplasty: What Is the Best Perioperative Analgesic Modality?: Commentary on an article by Rebecca L. Johnson, MD, et al.: "Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacain (PubMed)

Total Hip Arthroplasty: What Is the Best Perioperative Analgesic Modality?: Commentary on an article by Rebecca L. Johnson, MD, et al.: "Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacain 29088049 2017 10 31 1535-1386 99 21 2017 Nov 01 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Total Hip Arthroplasty: What Is the Best Perioperative Analgesic Modality?: Commentary on an article by Rebecca L (...) . Johnson, MD, et al.: "Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Total Hip Arthroplasty. A Three-Arm Randomized Clinical Trial". e117 10.2106/JBJS.17.00978 Li Xinning X Sports Medicine and Shoulder Surgery, Department of Orthopaedic Surgery, Boston University School of Medicine, Boston, Massachusetts. eng Journal Article United States J Bone Joint Surg Am 0014030 0021-9355 2017 11 1 6 0 2017 11 1 6 0 2017 11 1 6 0

2017 The Journal of Bone and Joint Surgery. American Volume Controlled trial quality: uncertain

52. Hip Pain: Dry Needling Versus Cortisone Injections. (PubMed)

Hip Pain: Dry Needling Versus Cortisone Injections. Greater trochanteric pain syndrome (GTPS) is chronic, intermittent pain and tenderness on the outside of the hip. The medical community once thought that a swollen hip bursa was the source of such pain, which led to the use of corticosteroid injections to the bursa to help decrease swelling and pain. However, researchers now believe that injuries to the muscles and tendons around the hip are the actual cause of this pain, and that inflammation (...) is often not involved. A study published in the April 2017 issue of JOSPT explores dry needling as an alternative to cortisone injections to reduce pain and improve function in patients with GTPS. J Orthop Sports Phys Ther 2017;47(4):240. doi:10.2519/jospt.2017.0504.

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2017 The Journal of orthopaedic and sports physical therapy Controlled trial quality: uncertain

53. Treatment of Early Hip Osteoarthritis: Ultrasound-Guided Platelet Rich Plasma versus Hyaluronic Acid Injections in a Randomized Clinical Trial (PubMed)

Treatment of Early Hip Osteoarthritis: Ultrasound-Guided Platelet Rich Plasma versus Hyaluronic Acid Injections in a Randomized Clinical Trial Purpose  The aim of this study was to compare the clinical efficacy of ultrasound-guided intra-articular injections of autologous platelet rich plasma (PRP) versus hyaluronic acid (HA) for symptomatic early osteoarthritis (OA) of the hip. Methods  A prospective controlled double-blinded randomized trial on 80 patients with hip OA was conducted (...) . The patients were divided in two groups of 40 patients each: group 1 underwent three PRP intra-articular ultrasound-guided injections, whereas group 2 underwent three HA injections. WOMAC, VAS, and Harris Hip Score were evaluated for both groups before and at 6 and 12 months after treatment. Results  The two groups were comparable in age, sex, body mass index, and severity of hip OA. Both groups showed a significant improvement from baseline at 6-month and 12-month follow-ups for all the outcome measures

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2017 Joints Controlled trial quality: uncertain

54. The effectiveness of intra-articular injections of Hyalubrix® combined with exercise therapy in the treatment of hip osteoarthritis (PubMed)

The effectiveness of intra-articular injections of Hyalubrix® combined with exercise therapy in the treatment of hip osteoarthritis Osteoarthritis (OA) is the most common joint disorder in the elderly, causing significant pain which negatively affects mobility and quality of life. The aim of the study was to assess the effectiveness of ultrasound image-guided intra-articular injections of Hyalubrix® combined with exercise therapy in the treatment of hip osteoarthritis.This was a single site (...) for a total of 65 treated hips demonstrate a significant improvement in OA-related pain, hip disability, and patient's daily functioning as well as a reduction in NSAIDs intake. Patients suffering from hip OA seem to benefit from the treatment with Hyalubrix® injections plus exercise therapy.

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2017 Clinical Cases in Mineral and Bone Metabolism Controlled trial quality: uncertain

55. Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Total Hip Arthroplasty: A Three-Arm Randomized Clinical Trial. (PubMed)

Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Total Hip Arthroplasty: A Three-Arm Randomized Clinical Trial. Debate surrounds the issue of whether peripheral nerve blockade or periarticular infiltration (PAI) should be employed within a contemporary, comprehensive multimodal analgesia pathway for total hip arthroplasty. We hypothesized that patients treated with a continuous posterior lumbar plexus block (PNB) would (...) report less pain and consume less opioid medication than those treated with PAI.This investigator-initiated, independently funded, 3-arm randomized clinical trial (RCT) performed at a single high-volume institution compared postoperative analgesia interventions for elective, unilateral primary total hip arthroplasty: (1) PNB; (2) PAI with ropivacaine, ketorolac, and epinephrine (PAI-R); and (3) PAI with liposomal bupivacaine, ketorolac, and epinephrine (PAI-L) using computerized randomization

2017 The Journal of Bone and Joint Surgery. American Volume Controlled trial quality: predicted high

56. The Effectiveness of Platelet-Rich Plasma Injections in Gluteal Tendinopathy: A Randomized, Double-Blind Controlled Trial Comparing a Single Platelet-Rich Plasma Injection With a Single Corticosteroid Injection

The Effectiveness of Platelet-Rich Plasma Injections in Gluteal Tendinopathy: A Randomized, Double-Blind Controlled Trial Comparing a Single Platelet-Rich Plasma Injection With a Single Corticosteroid Injection Gluteus medius/minimus tendinopathy is a common cause of lateral hip pain or greater trochanteric pain syndrome.There would be no difference in the modified Harris Hip Score (mHHS) between a single platelet-rich plasma (PRP) injection compared with a corticosteroid injection (...) in the treatment of gluteal tendinopathy.Randomized controlled trial; Level of evidence, 1.There were 228 consecutive patients referred with gluteal tendinopathy who were screened to enroll 80 participants; 148 were excluded (refusal: n = 42; previous surgery or sciatica: n = 50; osteoarthritis, n = 17; full-thickness tendon tear, n = 17; other: n = 22). Participants were randomized (1:1) to receive either a blinded glucocorticoid or PRP injection intratendinously under ultrasound guidance. A pain

2018 EvidenceUpdates

57. Chemical thromboprophylaxis after hip fracture surgery

Chemical thromboprophylaxis after hip fracture surgery Rapid Review 1 Chemical thromboprophylaxis after hip fracture surgery Citation Yap G., Joseph C. & Melder A. 2018. Chemical thromboprophylaxis after hip fracture surgery: Rapid Literature Review. Centre for Clinical Effectiveness, Monash Health, Melbourne, Australia. Contact cce@monashhealth.org Background Few studies are available in the literature reporting on the prevention of venous thromboembolism in patients with a hip fracture (...) compared to those with hip arthroplasty [2] . The Director of Orthopaedic Surgery requested a review of the evidence around the most suitable chemical thromboprophylaxis for patients who have undergone hip surgery. Objectives To determine the recommended chemical thromboprophylaxis (choice, dose and duration) for patients after hip fracture surgery in the prevention of venous thromboembolism (VTE); and improvement outcomes related to deep vein thrombosis (DVT), pulmonary embolism (PE), bleeding

2019 Monash Health Evidence Reviews

58. Intra-Articular Hyaluronic Acid for Osteoarthritis of the Hip or Ankle: A Review of Clinical Effectiveness

to osteoarthritis in the hip, no significant differences in pain or adverse events were found when compared with placebo or with methylprednisolone and no differences in function or patients’ global assessment were found when compared with methylprednisolone. For osteoarthritis of the ankle, the injection of hyaluronic acid was significantly associated with an improvement in measures of pain and disability scores when compared with saline. The results of this review should be interpreted with consideration (...) Intra-Articular Hyaluronic Acid for Osteoarthritis of the Hip or Ankle: A Review of Clinical Effectiveness Intra-Articular Hyaluronic Acid for Osteoarthritis of the Hip or Ankle: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Intra-Articular Hyaluronic Acid for Osteoarthritis of the Hip or Ankle: A Review of Clinical Effectiveness Intra-Articular Hyaluronic Acid for Osteoarthritis of the Hip or Ankle: A Review of Clinical Effectiveness Last updated: July 11, 2019

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

59. Hip fracture

medication with oral or injectable placebo plus calcium and vitamin D in a double-blinded fashion. Secondary (Timed Up-and-Go [TUG] test, hip pain, Short Form [SF]-36 health status, and safety) and exploratory 2016 8. Comparative effectiveness of pain management interventions for hip fracture : a systematic review Comparative effectiveness of pain management interventions for hip fracture : a systematic review Comparative effectiveness of pain management interventions for hip fracture : a systematic (...) Hip fracture Top results for hip fracture - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2

2018 Trip Latest and Greatest

60. How Effective Is a Regional Nerve Block for Treating Pain Associated With Hip Fractures?

How Effective Is a Regional Nerve Block for Treating Pain Associated With Hip Fractures? TAKE-HOME MESSAGE Regional nerve blockade reduces pain on movement, risk of pneumonia, and time to ?rst mobilization among patients with hip fractures with no major complications. How Effective Is a Regional Nerve Block for Treating Pain Associated With Hip Fractures? EBEM Commentators Michael Gottlieb, MD, RDMS Nicholas Chien, MD Thomas Seagraves, MD Department of Emergency Medicine Rush University Medical (...) independently assessed potentially eligible randomized controlled trials for inclusion. Disagreements were resolved by discussion between the 2 reviewers. DATA EXTRACTION AND SYNTHESIS Two authors independently extracted data and resolved PAIN MANAGEMENT AND SEDATION/SYSTEMATIC REVIEW SNAPSHOT 378 Annals of Emergency Medicine Volume 71, no. 3 : March 2018at overall low or moderate risk of bias. Commentary Hip fractures are a common emer- gency department (ED) presenta- tion,withmorethan300,000visits

2018 Annals of Emergency Medicine Systematic Review Snapshots

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