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High Pressure Injection Wound


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61. Side effects

pressure, osteoporosis, and development of diabetes mellitus. However (...) , whether a single steroid load during surgery has negative effects during the postoperative period has not yet been studied. OBJECTIVES: To assess the effects of a steroid load of dexamethasone on postoperative systemic or wound infection, delayed wound healing, and blood glucose change in adult surgical patients (with planned subgroup analysis of patients with and without diabetes). SEARCH METHODS: We searched MEDLINE, Embase (...) of evidence. If you wanted the latest trusted evidence on side effects or other clinical topics then use Trip today. This page lists the very latest high quality evidence on side effects and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months. What is Trip? Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice

2018 Trip Latest and Greatest

62. Nitroglycerin

of evidence. If you wanted the latest trusted evidence on nitroglycerin or other clinical topics then use Trip today. This page lists the very latest high quality evidence on nitroglycerin and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months. What is Trip? Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice (...) of STEMI prior to NTG administration. We sought to determine if NTG administration is more likely to be associated (...) with hypotension (systolic blood pressure < 90 mmHg) in inferior STEMI compared to non-inferior STEMI. We conducted a retrospective chart review of prehospital patients with chest pain of suspected cardiac origin and computer-interpreted prehospital ECGs indicating "ACUTE MI." We included all local STEMI cases identified as part of our STEMI registry. Univariate analysis was used

2018 Trip Latest and Greatest

63. Promethazine

of high-risk patients administered prophylactic ondansetron. All subjects enrolled were identified as high risk for PONV, administered general 2009 7. Ionophore-Based Potentiometric Sensors for the Flow-Injection Determination of Promethazine Hydrochloride in Pharmaceutical Formulations and Human Urine 22346617 2012 02 20 2012 07 09 2017 02 20 1424-8220 11 1 2011 Sensors (Basel, Switzerland) Sensors (Basel) Ionophore-based potentiometric sensors for the flow-injection determination of promethazine (...) wanted the latest trusted evidence on promethazine or other clinical topics then use Trip today. This page lists the very latest high quality evidence on promethazine and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months. What is Trip? Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care. Trip

2018 Trip Latest and Greatest

64. Hip fracture

of evidence. If you wanted the latest trusted evidence on hip fracture or other clinical topics then use Trip today. This page lists the very latest high quality evidence on hip fracture and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months. What is Trip? Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice (...) in older persons: an update Jenson C S Mak, Ian D Cameron and Lyn M March Med J Aust 2010; 192 (1): 37-41. Abstract (...) . Recommendations for time to surgery, thromboprophylaxis, anaesthesia, analgesia, prophylactic antibiotics, surgical fixation of fractures , nutritional status, mobilisation and rehabilitation have been updated. Also, recommendations regarding surgical wound closure, management of postoperative delirium, osteoporosis treatment and hip protectors have been added. The guidelines

2018 Trip Latest and Greatest

65. ESC/EACTS Guidelines on Myocardial Revascularization

contribution of the European Association for Percutaneous Cardiovascular Interventions (EAPCI) Table of contents Abbreviations and acronyms 90 1 Preamble 93 2 Introduction 94 2.1 What is new in the 2018 Guidelines? 95 3 Diagnostic tools to guide myocardial revascularization 96 3.1 Non-invasive diagnostic tools 96 3.1.1 Assessment of myocardial ischaemia 96 3.1.2 Assessment of myocardial viability in patients with heart failure and coronary artery disease 96 3.2 Invasive diagnostic tools 96 3.2.1 Pressure (...) -derived fractional flow reserve 96 Use of fractional flow reserve in patients with intermediate-grade coronary stenosis including left main stenosis 96 Use of fractional flow reserve to identify lesions requiring revascularization in patients with multivessel coronary artery disease undergoing percutaneous coronary intervention 97 Fractional flow reserve-guided management vs. medical therapy in patients with coronary artery disease 97 3.2.2 Other pressure-derived indices 97

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2018 European Society of Cardiology

66. Clinical Practice Guideline for the Management of Infantile Hemangiomas

who are at high risk require treatment with propranolol, it is advisable to use the lowest effective dose, slowly titrate the dose, and administer the drug 3 times daily (to minimize abrupt changes in blood pressure); comanagement with a pediatric neurologist is recommended. , , , Other patients who may require lower propranolol doses include those with progressive IH ulceration while receiving therapy and those who experience adverse effects (such as sleep disturbances). Key Action Statement 3C (...) , bronchospasm, bronchiolitis, and cold-induced wheezing), and a decrease in heart rate or blood pressure. Rates of clinically important harms (hypoglycemia, hypotension, bradycardia, and bronchospasm) varied widely across the studies, and the authors assigned a moderate SOE for the association of propranolol with both clinically important and minor harms (with high study limitations). Overall, harms did not cause treatment discontinuation. Our additional review yielded 8 reports that met inclusion criteria

2019 American Academy of Pediatrics

67. Primary postpartum haemorrhage

and maternal comfort o Repair ensuring bleeding at the apex of the laceration is secured o Refer to Queensland Clinical Guideline: Perineal Care 38 for repair principles Condition compromised · Treat shock [refer to Section 3.3 Resuscitation] o Apply pressure on the wound or bimanual compression o Assess analgesia requirements · Urgently transfer to OT for repair under anaesthetic o GA usually more appropriate when hemodynamically unstable Suboptimal wound visualisation · Transfer to OT · Maximise lighting (...) · Transfer to OT or to higher level facility as relevant · Refer to MHP flowchart Monitor: · Vital signs – assess for shock · Fundal tone · Vaginal blood loss · Haemoglobin Transfer as required to: · Postnatal area · Intensive care/high dependency · Higher level facility Postnatal care: · Provide psychological support: · Treat anaemia · Administer VTE prophylaxis o Monitor for DVT/PE · Follow-up and self-care advice Bleeding controlled? Coagulopathy may influence surgical decisions · Consider future

2019 Queensland Health

68. Iron Deficiency and Anaemia in Adults

>500 to 1000mg 250ml 15 minutes Note: For stability reasons, dilutions to concentrations less than 2mg iron/ml are not permissible. Ferinject must not be administered by the subcutaneous or intramuscular route. Minimum observation is required (pulse and blood pressure should be checked before and after infusion). Facilities for cardiorespiratory resuscitation and equipment for handling acute anaphylactic/anaphylactoid reactions should be available, including an injectable 1:1000 adrenaline solution (...) or irregular heartbeat. • Pounding or ‘whooshing’ in the ears. • Headache. • Cold hands or feet. • Pale skin. • Chest pain. • Lack of concentration. • Mouth ulcers or cracks at the corners of the mouth. • Slow or poor wound healing. • Tinnitus. (Arnott et al., 2013) Important questions to ask To determine the underlying cause of anaemia, questions about an individual’s lifestyle and medical history should be asked. These questions should cover the following areas. Diet Certain types of food preferences

2018 Royal College of Nursing

69. Global Vascular Guidelines for patients with chronic limb-threatening ischemia

CLTI should be referred urgently to a vascular specialist. Accurately staging the severity of limb threat is fundamental, and the Society for Vascular Surgery Threatened Limb Classification system, based on grading of Wounds, Ischemia, and foot Infection (WIfI) is endorsed. Objective hemodynamic testing, including toe pressures as the preferred measure, is required to assess CLTI. Evidence-based revascularization (EBR) hinges on three independent axes: Patient risk, Limb severity, and ANatomic (...) controlled trial SCS Spinal cord stimulation SF-12 12-Item Short-Form Health Survey SFA Superficial femoral artery SLI severe limb ischemia SCLI subcritical limb ischemia SVS Society for Vascular Surgery SYNTAX [System for coronary disease] TAP Target arterial path TBI Toe-brachial index TcP o 2 Transcutaneous oximetry TKA Through-knee amputation TP Toe pressure VascuQoL Vascular Quality of Life tool WFVS World Federation of Vascular Societies WIfI Wound, Ischemia, foot Infection Introduction Rationale

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2019 Society for Vascular Surgery

70. Clinical practice guideline on peri- and postoperative care of arteriovenous fistulas and grafts for haemodialysis in adults

of AV access creation or placement until AV access abandonment or permanent loss of the AV access (synonym: cumulative AV access survival; secondary assisted patency). Surveillance Overarching term referring to both clinical monitoring and technical surveillance of an AV access; it includes haemodialysis parameters such as pump speed, dialyser inlet and transmembrane pressure and indices of dialysis adequacy ( K t / V urea); sequential measurements with trend analysis of intra-access flow, dynamic (...) or static dialyser outlet pressure, AV access recirculation or AV access duplex ultrasound assessment. Technical surveillance Assessment of an AV access at regular intervals using a specialized apparatus; distinct from clinical monitoring. AV access Overarching term referring to both AV fistulas and AV grafts. AV access thrombosis Blood clot obstructing the AV access; indicates loss of anatomic, haemodynamic and clinical patency. AV fistula Surgically created autogenous vascular access used for chronic

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2019 European Renal Best Practice

71. Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures

to children. Abbreviations: AAP — American Academy of Pediatrics AAPD — American Academy of Pediatric Dentistry ASA — American Society of Anesthesiologists BIS — bispectral index CPAP — continuous positive airway pressure ECG — electrocardiography EEG — electroencephalogram/electroencephalography EMS — emergency medical services LMA — laryngeal mask airway MRI — magnetic resonance imaging OSA — obstructive sleep apnea PALS — pediatric advanced life support Introduction The number of diagnostic and minor (...) patients both during and after sedation for a procedure. The monitoring and care outlined may be exceeded at any time on the basis of the judgment of the responsible practitioner. Although intended to encourage high-quality patient care, adherence to the recommendations in this document cannot guarantee a specific patient outcome. However, structured sedation protocols designed to incorporate these safety principles have been widely implemented and shown to reduce morbidity. These practice

2019 American Academy of Pediatrics

72. Darvadstrocel (Alofisel) - non-active / mildly active luminal Crohn’s disease

Darvadstrocel (Alofisel) - non-active / mildly active luminal Crohn’s disease 1 Published 8 July 2019 1 SMC2115 darvadstrocel 30 million cells/6mL suspension for injection (Alofisel®) Takeda UK Ltd 7 December 2018 (Issued June 2019) The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use in NHSScotland. The advice is summarised as follows: ADVICE: following a full submission (...) to the administration of darvadstrocel, if setons are in place, they must be removed and the fistula tracts should be conditioned as follows: - identify the location of the internal openings. For this, it is recommended to inject sodium chloride 9mg/mL (0.9%) solution through the external openings until it gets through the internal openings. - perform a vigorous curettage of all fistula tracts, with special emphasis in the internal openings areas, using a metallic curette. - suture the internal openings to close

2019 Scottish Medicines Consortium

73. WHO consolidated guideline on self-care interventions for health: sexual and reproductive health and rights

122 95 116 89 112 122 98 92 112 123 77 4.4 Combating sexually transmitted infections (including HIV), reproductive tract infections, cervical cancer and other gynaecological morbidities 4.3 Eliminating unsafe abortion 4.2 Providing high- quality services for family planning, including infertility services 4.1 Improving antenatal care, delivery, postpartum and newborn care 5.1 Overview 6.1 Research on self-care contributing to WHO’s “triple billion” goals 7.1 Dissemination 5.4 Training needs (...) / AIDS [UNAIDS]), Lucinda O’Hanlon (Office of the United Nations High Commissioner for Human Rights [OHCHR]), Shaffiq Essajee (United Nations Children’s Fund [UNICEF]), Kenechukwu Esom (United Nations Development Programme [UNDP]), Ayman Abdelmohsen, Petra ten Hoope-Bender and Tim Sladden (United Nations Population Fund [UNFPA]) and David Wilson (World Bank). The following WHO staff members contributed as members of the WHO Guideline Steering Group (SG), which managed the guideline development

2019 World Health Organisation Guidelines

74. Compression therapy after invasive treatment of superficial veins of the lower extremities

of high stiffness around the leg, even when their individual components are elastic. This stiffness of elastic textiles results in an increase of sub-bandage pressure when patients stand up or when they walk. x 5 Kalodiki, E. Use of intermittent pneumatic compression in the treatment of venous ulcers. Future Cardio . 2007 ; 3 : 185–191 | | | Examples are “multilayer bandages” like Profore (Smith & Nephew, Memphis, Tenn), Comprifore (Jobst, Charlotte, NC), and Coban 2 (3M, St. Paul, Minn) as a “two (...) is that it provides even higher sub-bandage pressures in the upright body position and when the patient is walking, whereas the pressure is tolerably low during rest. x 7 Moffatt, C. Variability of pressure provided by sustained compression. Int Wound J . 2008 ; 5 : 259–265 | | | The effects of the intermittent pressure peaks during walking are comparable to those of intermittent pneumatic compression pumps, for which there is more evidence concerning hemodynamic efficacy published than for bandages. x 5 Kalodiki

2019 American Venous Forum

75. ACR–ASNR Practice Parameter for the Performance of Computed Tomography (CT) of the Brain

of Neuroradiology (ASNR), and the Society for Pediatric Radiology (SPR). Computed tomography (CT) is a technology that produces cross-sectional images of the body using x-rays. Computed tomography (CT) is utilized extensively in imaging of the brain. This practice parameter outlines the principles for performing high-quality CT imaging of the brain in pediatric and adult patients. There should be an effort to minimize radiation exposure, particularly in children. An alternate modality should be considered when (...) evaluation following surgical treatment of tumor, intracranial hemorrhage, or hemorrhagic lesions [30] 7. Treated or untreated vascular lesions [31,32] 8. Mental status change [33] 9. Increased intracranial pressure [3,4] 10. Headache [34,35] 11. Acute neurologic deficits [36] 12. Suspected intracranial infection [37-43] 13. Suspected hydrocephalus [44-46] 14. Certain congenital skull and brain lesions (such as, but not limited to, craniosynostosis, macrocephaly, and microcephaly) [6,47,48] 15

2019 American Society of Neuroradiology

76. Paediatric Urology

., et al. Correction of congenital penile curvature using modified tunical plication with absorbable sutures: the long-term outcome and patient satisfaction. Eur Urol, 2007. 52: 261. 271. Sasso, F., et al. Penile curvature: an update for management from 20 years experience in a high volume centre. Urologia, 2016. 83: 130. 272. Gittes, R.F., et al. Injection technique to induce penile erection. Urology, 1974. 4: 473. 273. Schultheiss, D., et al. Congenital and acquired penile deviation treated (...) therapy with LHRH and HCG in cryptorchid infants. Eur J Pediatr, 1993. 152 Suppl 2: S31. 66. Forest, M.G., et al. Effects of human chorionic gonadotropin, androgens, adrenocorticotropin hormone, dexamethasone and hyperprolactinemia on plasma sex steroid-binding protein. Ann N Y Acad Sci, 1988. 538: 214. 67. Aycan, Z., et al. Evaluation of low-dose hCG treatment for cryptorchidism. Turk J Pediatr, 2006. 48: 228. 68. Hesse, V., et al. Three injections of human chorionic gonadotropin are as effective

2019 European Association of Urology

77. Male Sexual Dysfunction

(penile rehabilitation) in the patient after brachytherapy for prostate cancer. Brachytherapy, 2012. 11: 87. 82. Cordeiro, E.R., et al. High-intensity focused ultrasound (HIFU) for definitive treatment of prostate cancer. BJU Int, 2012. 110: 1228. 83. Williams, S.B., et al. Comparative effectiveness of cryotherapy vs brachytherapy for localised prostate cancer. BJU Int, 2012. 110: E92. 84. Hatzichristou, D., et al. Diagnosing Sexual Dysfunction in Men and Women: Sexual History Taking and the Role (...) : reproducibility, evaluation criteria and the effect of sexual intercourse. J Urol, 1998. 159: 1921. 110. Hatzichristou, D.G., et al. Hemodynamic characterization of a functional erection. Arterial and corporeal veno-occlusive function in patients with a positive intracavernosal injection test. Eur Urol, 1999. 36: 60. 111. Sikka, S.C., et al. Standardization of vascular assessment of erectile dysfunction: standard operating procedures for duplex ultrasound. J Sex Med, 2013. 10: 120. 112. Pathak, R.A., et al

2019 European Association of Urology

78. Penile Cancer

. Cancer Incidence in Five Continents Vol. VIII. IARC Scientific Publication No. 155. Vol. Vol III. 2002, The International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon CEDEX 08, France. 16. Parkin, D.M., et al. Chapter 2: The burden of HPV-related cancers. Vaccine, 2006. 24 Suppl 3: S3/11. 17. Baldur-Felskov, B., et al. Increased incidence of penile cancer and high-grade penile intraepithelial neoplasia in Denmark 1978-2008: a nationwide population-based study. Cancer Causes (...) . Etiology of squamous cell carcinoma of the penis. Scand J Urol Nephrol Suppl, 2000: 189. 22. Maden, C., et al. History of circumcision, medical conditions, and sexual activity and risk of penile cancer. J Natl Cancer Inst, 1993. 85: 19. 23. Tsen, H.F., et al. Risk factors for penile cancer: results of a population-based case-control study in Los Angeles County (United States). Cancer Causes Control, 2001. 12: 267. 24. Afonso, L.A., et al. High Risk Human Papillomavirus Infection of the Foreskin

2019 European Association of Urology

79. Diagnosis and Prevention of Periprosthetic Joint Infections

Evidence-Based Clinical Practice Guidelines and Appropriate Use Criteria in a User-Friendly Format, Please Visit the OrthoGuidelines Web-Based App at or by downloading to your smartphone or tablet via the Apple and Google Play stores! 4 View the background material via the PJI CPG eAppendix 1 View data summaries via the PJI CPG eAppendix 2 Table of Contents Summary of Recommendations 6 Risk Factors for PJI 6 Injections Prior to Arthroplasty 7 Blood Tests for Preoperative (...) of the Recommendations 18 Voting on the Recommendations 18 Interpreting the Strength of Evidence 19 Peer Review 20 Public Commentary 20 The AAOS Clinical practice guideline Approval Process 20 Revision Plans 20 Clinical practice guideline Dissemination Plans 20 5 View the background material via the PJI CPG eAppendix 1 View data summaries via the PJI CPG eAppendix 2 Study Attrition Flowchart 21 Recommendations 22 Risk Factors for PJI 22 Injections Prior to Arthroplasty 31 Blood Tests for Preoperative Diagnosis 32

2019 American Academy of Orthopaedic Surgeons

80. Prostate Cancer

Broeck T., et al. A systematic review of oncological effectiveness and harms of primary local interventions for high-risk localized and locally advanced prostate cancer. PROSPERO International prospective register of systematic reviews, 2017. CRD42017078862 8. Willemse, P.M., et al. Systematic review of deferred treatment with curative intent for localised prostate cancer to explore heterogeneity of definitions, thresholds and criteria and clinical effectiveness. PROSPERO International prospective (...) . 29. Esposito, K., et al. Effect of metabolic syndrome and its components on prostate cancer risk: meta-analysis. J Endocrinol Invest, 2013. 36: 132. 30. Blanc-Lapierre, A., et al. Metabolic syndrome and prostate cancer risk in a population-based case-control study in Montreal, Canada. BMC Public Health, 2015. 15: 913. 31. Preston, M.A., et al. Metformin use and prostate cancer risk. Eur Urol, 2014. 66: 1012. 32. Freedland, S.J., et al. Statin use and risk of prostate cancer and high-grade

2019 European Association of Urology

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